PDB: 17012 件ウェブページステータス検索Chemie searchBIRD

---

1BHX	X-RAY STRUCTURE OF THE COMPLEX OF HUMAN ALPHA THROMBIN WITH THE INHIBITOR SDZ 229-357 分子名称: 5-OXO-6-PHENYLMETHANESULFONYLAMINO-HEXAHYDRO-THIAZOLO[3,2-A]PYRIDINE-3-CARBOXYLIC ACID (3-GUANIDINO-PROPYL)-AMIDE, ALPHA THROMBIN 著者 Kallen, J. 登録日 1998-06-10 公開日 1998-11-04 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Rational design, synthesis, and X-ray structure of selective noncovalent thrombin inhibitors. J.Med.Chem., 41, 1998
1BFJ	SOLUTION STRUCTURE OF THE C-TERMINAL SH2 DOMAIN OF THE P85ALPHA REGULATORY SUBUNIT OF PHOSPHOINOSITIDE 3-KINASE, NMR, MINIMIZED AVERAGE STRUCTURE 分子名称: P85 ALPHA 著者 Siegal, G, Davis, B, Kristensen, S.M, Sankar, A, Linacre, J, Stein, R.C, Panayotou, G, Waterfield, M.D, Driscoll, P.C. 登録日 1997-11-18 公開日 1998-02-25 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structure of the C-terminal SH2 domain of the p85 alpha regulatory subunit of phosphoinositide 3-kinase. J.Mol.Biol., 276, 1998
1DZV	L-Fuculose-1-Phosphate Aldolase from Escherichia coli Mutant Y113F/Y209F 分子名称: BETA-MERCAPTOETHANOL, L-fuculose phosphate aldolase, SULFATE ION, ... 著者 Joerger, A.C, Schulz, G.E. 登録日 2000-03-07 公開日 2000-06-02 最終更新日 2019-09-25 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Catalytic Action of Fuculose 1-Phosphate Aldolase (Class II) as Derived from Structure-Directed Mutagenesis Biochemistry, 39, 2000
1E1V	HUMAN CYCLIN DEPENDENT KINASE 2 COMPLEXED WITH THE INHIBITOR NU2058 分子名称: 6-O-CYCLOHEXYLMETHYL GUANINE, CYCLIN-DEPENDENT PROTEIN KINASE 2 著者 Endicott, J.A, Noble, M.E.M, Johnson, L.N. 登録日 2000-05-11 公開日 2001-05-10 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Identification of Novel Purine and Pyrimidine Cyclin-Dependent Kinase Inhibitors with Distinct Molecular Interactions and Tumor Cell Growth Inhibition Profiles. J.Med.Chem., 43, 2000
4FIC	Kinase domain of cSrc in complex with a hinge region-binding fragment 分子名称: 6-phenyl[1,2,4]triazolo[1,5-a]pyrazin-2-amine, Proto-oncogene tyrosine-protein kinase Src 著者 Richters, A, Rauh, D. 登録日 2012-06-08 公開日 2013-04-10 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 De novo design of protein kinase inhibitors by in silico identification of hinge region-binding fragments. Acs Chem.Biol., 8, 2013
1DZU	L-Fuculose-1-Phosphate Aldolase from Escherichia coli Mutant T26A 分子名称: BETA-MERCAPTOETHANOL, L-fuculose phosphate aldolase, SULFATE ION, ... 著者 Joerger, A.C, Schulz, G.E. 登録日 2000-03-07 公開日 2000-06-02 最終更新日 2019-09-25 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Catalytic Action of Fuculose 1-Phosphate Aldolase (Class II) as Derived from Structure-Directed Mutagenesis Biochemistry, 39, 2000
1DZY	L-Fuculose-1-Phosphate Aldolase from Escherichia coli Mutant E214A 分子名称: BETA-MERCAPTOETHANOL, L-FUCULOSE-1-PHOSPHATE ALDOLASE, SULFATE ION, ... 著者 Joerger, A.C, Schulz, G.E. 登録日 2000-03-07 公開日 2000-06-02 最終更新日 2019-01-30 実験手法 X-RAY DIFFRACTION (2.44 Å) 主引用文献 Catalytic Action of Fuculose 1-Phosphate Aldolase (Class II) as Derived from Structure-Directed Mutagenesis Biochemistry, 39, 2000
4FIV	FIV PROTEASE COMPLEXED WITH AN INHIBITOR LP-130 分子名称: 4-[2-(2-ACETYLAMINO-3-NAPHTALEN-1-YL-PROPIONYLAMINO)-4-METHYL-PENTANOYLAMINO]-3-HYDROXY-6-METHYL-HEPTANOIC ACID [1-(1-CARBAMOYL-2-NAPHTHALEN-1-YL-ETHYLCARBAMOYL)-PROPYL]-AMIDE, FELINE IMMUNODEFICIENCY VIRUS PROTEASE 著者 Kervinen, J, Lubkowski, J, Zdanov, A, Wlodawer, A, Gustchina, A. 登録日 1998-07-15 公開日 1999-01-13 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Toward a universal inhibitor of retroviral proteases: comparative analysis of the interactions of LP-130 complexed with proteases from HIV-1, FIV, and EIAV. Protein Sci., 7, 1998
1CIS	CONTEXT DEPENDENCE OF PROTEIN SECONDARY STRUCTURE FORMATION. THE THREE-DIMENSIONAL STRUCTURE AND STABILITY OF A HYBRID BETWEEN CHYMOTRYPSIN INHIBITOR 2 AND HELIX E FROM SUBTILISIN CARLSBERG 分子名称: HYBRID PROTEIN FORMED FROM CHYMOTRYPSIN INHIBITOR-2 著者 Osmark, P, Sorensen, P, Poulsen, F.M. 登録日 1993-04-23 公開日 1993-10-31 最終更新日 2024-04-10 実験手法 SOLUTION NMR 主引用文献 Context dependence of protein secondary structure formation: the three-dimensional structure and stability of a hybrid between chymotrypsin inhibitor 2 and helix E from subtilisin Carlsberg. Biochemistry, 32, 1993
1DZZ	L-Fuculose-1-Phosphate Aldolase from Escherichia coli Mutant Y113F 分子名称: BETA-MERCAPTOETHANOL, L-fuculose phosphate aldolase, SULFATE ION, ... 著者 Joerger, A.C, Schulz, G.E. 登録日 2000-03-07 公開日 2000-06-02 最終更新日 2019-09-25 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Catalytic Action of Fuculose 1-Phosphate Aldolase (Class II) as Derived from Structure-Directed Mutagenesis Biochemistry, 39, 2000
4G2R	Crystal Structure of the carboxyltransferase subunit of ACC (AccD6) in complex with inhibitor haloxyfop from Mycobacterium tuberculosis 分子名称: (2R)-2-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid, AccD6, Carboxyltransferase beta-subunit of Acyl-CoA Carboxylase 著者 Reddy, M.C.M, Bruning, J.B, Thurman, C, Sherekar, M, Valluru, S, Ehrenfeld, H, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) 登録日 2012-07-12 公開日 2014-02-19 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Structure, Activity, and Inhibition of the Carboxyltransferase beta-Subunit of Acetyl Coenzyme A Carboxylase (AccD6) from Mycobacterium tuberculosis. Antimicrob.Agents Chemother., 58, 2014
1EIW	Solution structure of hypothetical protein MTH538 from Methanobacterium thermoautotrophicum 分子名称: HYPOTHETICAL PROTEIN MTH538 著者 Cort, J.R, Arrowsmith, C.H, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) 登録日 2000-02-29 公開日 2000-09-06 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structure-based functional classification of hypothetical protein MTH538 from Methanobacterium thermoautotrophicum. J.Mol.Biol., 302, 2000
3IFN	X-ray structure of amyloid beta peptide:antibody (Abeta1-40:12A11) complex 分子名称: 12A11 FAB antibody heavy chain, 12A11 FAB antibody light chain, Amyloid beta A4 protein 著者 Weis, W.I, Feinberg, H, Basi, G.S, Schenk, D. 登録日 2009-07-24 公開日 2009-11-17 最終更新日 2013-06-19 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural correlates of antibodies associated with acute reversal of amyloid beta-related behavioral deficits in a mouse model of Alzheimer disease. J.Biol.Chem., 285, 2010
3II9	Crystal structure of glutaryl-coa dehydrogenase from Burkholderia pseudomallei at 1.73 Angstrom 分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Glutaryl-CoA dehydrogenase, ... 著者 Ismagilov, R.F, Li, L, Du, W.B, Staker, B, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D), Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2009-07-31 公開日 2009-12-15 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 User-loaded SlipChip for equipment-free multiplexed nanoliter-scale experiments. J.Am.Chem.Soc., 132, 2010
3IK1	Lactobacillus casei Thymidylate Synthase in Ternary Complex with dUMP and the Phtalimidic Derivative 20C 分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 2-hydroxy-4-(4-methyl-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)benzoic acid, Thymidylate synthase 著者 Pozzi, C, Cancian, L, Leone, R, Luciani, R, Ferrari, S, Mangani, S, Costi, M.P. 登録日 2009-08-05 公開日 2010-08-11 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Identification of the binding modes of N-phenylphthalimides inhibiting bacterial thymidylate synthase through X-ray crystallography screening J.Med.Chem., 54, 2011
3IR2	Crystal structure of the APOBEC3G catalytic domain 分子名称: CHLORIDE ION, DNA dC->dU-editing enzyme APOBEC-3G, MAGNESIUM ION, ... 著者 Shandilya, S.M.D, Schiffer, C.A. 登録日 2009-08-21 公開日 2010-01-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal Structure of the APOBEC3G Catalytic Domain Reveals Potential Oligomerization Interfaces. Structure, 18, 2010
3IFO	X-ray structure of amyloid beta peptide:antibody (Abeta1-7:10D5) complex 分子名称: 10D5 FAB antibody heavy chain, 10D5 FAB antibody light chain, Amyloid beta A4 protein 著者 Weis, W.I, Feinberg, H, Basi, G.S, Schenk, D. 登録日 2009-07-24 公開日 2009-11-17 最終更新日 2013-09-25 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structural correlates of antibodies associated with acute reversal of amyloid beta-related behavioral deficits in a mouse model of Alzheimer disease. J.Biol.Chem., 285, 2010
3EFT	Crystal structure of the complex between Carbonic Anhydrase II and a spin-labeled sulfonamide incorporating TEMPO moiety 分子名称: 3-chloro-4-{[(1-hydroxy-2,2,6,6-tetramethylpiperidin-4-yl)carbamothioyl]amino}benzenesulfonamide, Carbonic anhydrase 2, MERCURY (II) ION, ... 著者 Temperini, C, Cecchi, A, Scozzafava, A, Supuran, C.T. 登録日 2008-09-10 公開日 2009-09-08 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Dissecting the Inhibition Mechanism of Cytosolic versus Transmembrane Carbonic Anhydrases by ESR J.Phys.Chem.B, 113, 2009
3IL1	Crystal structure of the AMPA subunit GluR2 bound to the allosteric modulator, IDRA-21 分子名称: (3S)-7-chloro-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide, GLUTAMIC ACID, Glutamate receptor 2, ... 著者 Ahmed, A.H, Ptak, C.P, Oswald, R.E. 登録日 2009-08-06 公開日 2009-09-15 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.998 Å) 主引用文献 Probing the allosteric modulator binding site of GluR2 with thiazide derivatives Biochemistry, 48, 2009
2RPF	RecO-bound ssDNA 分子名称: DNA (5'-D(*DTP*DAP*DCP*DG)-3') 著者 Masuda, T, Ito, Y, Shibata, T, Mikawa, T. 登録日 2008-05-15 公開日 2009-05-26 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 A non-canonical DNA structure enables homologous recombination in various genetic systems J.Biol.Chem., 284, 2009
3EDR	The crystal structure of caspase-7 in complex with Acetyl-LDESD-CHO 分子名称: Caspase-7, Inhibitor Ac-ldesd-cho peptide 著者 Agniswamy, J. 登録日 2008-09-03 公開日 2008-10-28 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Structural basis for executioner caspase recognition of P5 position in substrates. Apoptosis, 13, 2008
3ILT	Crystal structure of the AMPA subunit GluR2 bound to the allosteric modulator, trichlormethiazide 分子名称: 6-CHLORO-3-(DICHLOROMETHYL)-3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE-7-SULFONAMIDE 1,1-DIOXIDE, GLUTAMIC ACID, Glutamate receptor 2, ... 著者 Ahmed, A.H, Ptak, C.P, Oswald, R.E. 登録日 2009-08-07 公開日 2009-09-15 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.107 Å) 主引用文献 Probing the allosteric modulator binding site of GluR2 with thiazide derivatives Biochemistry, 48, 2009
3EJZ	Structure of E203V mutant E.coli Cl-/H+ exchanger, CLC-ec1 分子名称: BROMIDE ION, Fab fragment, Heavy chain, ... 著者 Lim, H.-H, Miller, C. 登録日 2008-09-18 公開日 2009-02-17 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Intracellular proton-transfer mutants in a CLC Cl-/H+ exchanger. J.Gen.Physiol., 133, 2009
3IFP	X-ray structure of amyloid beta peptide:antibody (Abeta1-7:12B4) complex 分子名称: 12B4 FAB antibody heavy chain, 12B4 FAB antibody light chain, Amyloid beta A4 protein 著者 Weis, W.I, Feinberg, H, Basi, G.S, Schenk, D. 登録日 2009-07-24 公開日 2009-11-17 最終更新日 2013-09-25 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Structural correlates of antibodies associated with acute reversal of amyloid beta-related behavioral deficits in a mouse model of Alzheimer disease. J.Biol.Chem., 285, 2010
3IK6	Crystal structure of the AMPA subunit GluR2 bound to the allosteric modulator, chlorothiazide 分子名称: 6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, GLUTAMIC ACID, Glutamate receptor 2, ... 著者 Ptak, C.P, Ahmed, A.H, Oswald, R.E. 登録日 2009-08-05 公開日 2009-09-15 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.101 Å) 主引用文献 Probing the allosteric modulator binding site of GluR2 with thiazide derivatives Biochemistry, 48, 2009

<222223224225226227228229230231232233234235236237>