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4DTU
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BU of 4dtu by Molmil
RB69 DNA Polymerase Ternary Complex with dGTP Opposite an Abasic Site and ddC/dG as the Penultimate Base-pair
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ...
著者Xia, S, Wang, J, Konigsberg, W.H.
登録日2012-02-21
公開日2012-06-06
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Contribution of Partial Charge Interactions and Base Stacking to the Efficiency of Primer Extension at and beyond Abasic Sites in DNA.
Biochemistry, 51, 2012
8B8V
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BU of 8b8v by Molmil
Crystal structure of the Rabies virus RNA free nucleoprotein- phosphoprotein complex
分子名称: DI(HYDROXYETHYL)ETHER, Nucleoprotein, Phosphoprotein
著者Gerard, F.C.A, Jamin, M, Bourhis, J.M.
登録日2022-10-05
公開日2023-03-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure and Dynamics of the Unassembled Nucleoprotein of Rabies Virus in Complex with Its Phosphoprotein Chaperone Module.
Viruses, 14, 2022
4DTN
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BU of 4dtn by Molmil
RB69 DNA Polymerase Ternary Complex with dATP Opposite an Abasic Site and ddA/dT as the Penultimate Base-pair
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ...
著者Xia, S, Wang, J, Konigsberg, W.H.
登録日2012-02-21
公開日2012-06-06
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Contribution of Partial Charge Interactions and Base Stacking to the Efficiency of Primer Extension at and beyond Abasic Sites in DNA.
Biochemistry, 51, 2012
4DTS
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BU of 4dts by Molmil
RB69 DNA Polymerase Ternary Complex with dCTP Opposite an Abasic Site and ddC/dG as the Penultimate Base-pair
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ...
著者Xia, S, Wang, J, Konigsberg, W.H.
登録日2012-02-21
公開日2012-06-06
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Contribution of Partial Charge Interactions and Base Stacking to the Efficiency of Primer Extension at and beyond Abasic Sites in DNA.
Biochemistry, 51, 2012
1Q1H
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BU of 1q1h by Molmil
An extended winged helix domain in general transcription factor E/IIE alpha
分子名称: Transcription Factor E
著者Meinhart, A, Blobel, J, Cramer, P.
登録日2003-07-21
公開日2003-12-09
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献An Extended Winged Helix Domain in General Transcription Factor E/IIE alpha
J.Biol.Chem., 278, 2003
5V3H
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BU of 5v3h by Molmil
Crystal structure of SMYD2 with SAM and EPZ033294
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Boriack-Sjodin, P.A.
登録日2017-03-07
公開日2018-04-25
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Small molecule inhibitors and CRISPR/Cas9 mutagenesis demonstrate that SMYD2 and SMYD3 activity are dispensable for autonomous cancer cell proliferation.
Plos One, 13, 2018
3TN9
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BU of 3tn9 by Molmil
X-ray structure of the HRV2 empty capsid (B-particle)
分子名称: Protein VP1, Protein VP2, Protein VP3
著者Garriga, D, Pickl-Herk, A, Luque, D, Wruss, J, Caston, J.R, Blaas, D, Verdaguer, N.
登録日2011-09-01
公開日2012-03-28
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Insights into minor group rhinovirus uncoating: the X-ray structure of the HRV2 empty capsid.
Plos Pathog., 8, 2012
2OUG
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BU of 2oug by Molmil
Crystal structure of the RfaH transcription factor at 2.1A resolution
分子名称: Transcriptional activator rfaH
著者Vassylyev, D.G, Vassylyeva, M.N, Svetlov, V, Artsimovitch, I.
登録日2007-02-10
公開日2007-05-01
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for converting a general transcription factor into an operon-specific virulence regulator.
Mol.Cell, 26, 2007
6CKX
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BU of 6ckx by Molmil
Structure of CDK12/CycK in complex with a small molecule inhibitor N-(4-(1-methyl-1H-pyrazol-4-yl)phenyl)-N-((1r,4r)-4-(quinazolin-2-ylamino)cyclohexyl)acetamide
分子名称: Cyclin-K, Cyclin-dependent kinase 12, MAGNESIUM ION, ...
著者Klein, M.G.
登録日2018-03-01
公開日2018-08-29
最終更新日2018-09-26
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Discovery of 3-Benzyl-1-( trans-4-((5-cyanopyridin-2-yl)amino)cyclohexyl)-1-arylurea Derivatives as Novel and Selective Cyclin-Dependent Kinase 12 (CDK12) Inhibitors.
J. Med. Chem., 61, 2018
8D33
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BU of 8d33 by Molmil
Human mitochondrial DNA polymerase gamma ternary complex with GC basepair
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (25-MER), ...
著者Park, J, Yin, Y.W.
登録日2022-05-31
公開日2023-05-24
最終更新日2023-07-05
実験手法ELECTRON MICROSCOPY (2.46 Å)
主引用文献Pol gamma coordinates DNA synthesis and proofreading to ensure mitochondrial genome integrity.
Nat.Struct.Mol.Biol., 30, 2023
3BLH
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BU of 3blh by Molmil
Crystal Structure of Human CDK9/cyclinT1
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cell division protein kinase 9, Cyclin-T1
著者Baumli, S, Lolli, G, Lowe, E.D, Johnson, L.N.
登録日2007-12-11
公開日2008-07-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献The structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation
Embo J., 27, 2008
7M09
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BU of 7m09 by Molmil
Pre-catalytic quaternary complex of DNA Polymerase Lambda with blunt-ended DSB substrate and incoming dUMPNPP
分子名称: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CALCIUM ION, CHLORIDE ION, ...
著者Kaminski, A.M, Bebenek, K, Pedersen, L.C, Kunkel, T.A.
登録日2021-03-10
公開日2022-03-16
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Analysis of diverse double-strand break synapsis with Pol lambda reveals basis for unique substrate specificity in nonhomologous end-joining.
Nat Commun, 13, 2022
7M0D
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BU of 7m0d by Molmil
Pre-catalytic quaternary complex of DNA Polymerase Lambda with bound complementary DSB substrate and incoming dUMPNPP
分子名称: 1,2-ETHANEDIOL, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
著者Kaminski, A.M, Bebenek, K, Pedersen, L.C, Kunkel, T.A.
登録日2021-03-10
公開日2022-03-16
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Analysis of diverse double-strand break synapsis with Pol lambda reveals basis for unique substrate specificity in nonhomologous end-joining.
Nat Commun, 13, 2022
7M0B
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BU of 7m0b by Molmil
Pre-catalytic quaternary complex of DNA Polymerase Lambda with bound mismatched DSB and incoming dUMPNPP
分子名称: 1,2-ETHANEDIOL, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, ...
著者Kaminski, A.M, Bebenek, K, Pedersen, L.C, Kunkel, T.A.
登録日2021-03-10
公開日2022-03-16
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Analysis of diverse double-strand break synapsis with Pol lambda reveals basis for unique substrate specificity in nonhomologous end-joining.
Nat Commun, 13, 2022
3BLR
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BU of 3blr by Molmil
Crystal Structure of Human CDK9/cyclinT1 in complex with Flavopiridol
分子名称: 2-(2-CHLORO-PHENYL)-5,7-DIHYDROXY-8-(3-HYDROXY-1-METHYL-PIPERIDIN-4-YL)-4H-BENZOPYRAN-4-ONE, Cell division protein kinase 9, Cyclin-T1, ...
著者Baumli, S, Lolli, G, Lowe, E.D, Johnson, L.N.
登録日2007-12-11
公開日2008-07-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation
Embo J., 27, 2008
4C0B
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BU of 4c0b by Molmil
Structure of wild-type Clp1p-Pcf11p (454 -563) complex
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, MRNA CLEAVAGE AND POLYADENYLATION FACTOR CLP1, ...
著者Fribourg, S, Dupin, A.F.
登録日2013-08-01
公開日2014-02-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.77 Å)
主引用文献Structural basis for ATP loss by Clp1p in a G135R mutant protein.
Biochimie, 101, 2014
2IVX
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BU of 2ivx by Molmil
Crystal structure of human cyclin T2 at 1.8 A resolution
分子名称: 1,2-ETHANEDIOL, CYCLIN-T2
著者Debreczeni, J.E, Bullock, A.N, Fedorov, O, Savitsky, P, Berridge, G, Das, S, Pike, A.C.W, Turnbull, A, Ugochukwu, E, Papagrigoriou, E, Gorrec, F, Sundstrom, M, Edwards, A, Arrowsmith, C, Weigelt, J, von Delft, F, Knapp, S.
登録日2006-06-21
公開日2006-07-19
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation.
EMBO J., 27, 2008
5HBM
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BU of 5hbm by Molmil
Crystal Structure of a Dihydroxycoumarin RNase H Active-Site Inhibitor in Complex with HIV-1 Reverse Transcriptase
分子名称: (7,8-dihydroxy-2-oxo-2H-chromen-4-yl)acetic acid, 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, MANGANESE (II) ION, ...
著者Kirby, K.A, Sarafianos, S.G.
登録日2015-12-31
公開日2016-02-24
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.043 Å)
主引用文献Crystal Structure of a Dihydroxycoumarin RNase H Active-Site Inhibitor in Complex with HIV-1 Reverse Transcriptase
To Be Published
6DU3
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BU of 6du3 by Molmil
Structure of Scp1 D96N bound to REST-pS861/4 peptide
分子名称: Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, MAGNESIUM ION, REST-pS861
著者Burkholder, N.T, Mayfield, J.E, Yu, X, Irani, S, Arce, D.K, Jiang, F, Matthews, W, Xue, Y, Zhang, Y.J.
登録日2018-06-19
公開日2018-09-26
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Phosphatase activity of small C-terminal domain phosphatase 1 (SCP1) controls the stability of the key neuronal regulator RE1-silencing transcription factor (REST).
J. Biol. Chem., 293, 2018
6DU2
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BU of 6du2 by Molmil
Structure of Scp1 D96N bound to REST-pS861/4 peptide
分子名称: MAGNESIUM ION, REST-pS861/4, carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform X2
著者Burkholder, N.T, Mayfield, J.E, Yu, X, Irani, S, Arce, D.K, Jiang, F, Matthews, W, Xue, Y, Zhang, Y.J.
登録日2018-06-19
公開日2018-09-26
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Phosphatase activity of small C-terminal domain phosphatase 1 (SCP1) controls the stability of the key neuronal regulator RE1-silencing transcription factor (REST).
J. Biol. Chem., 293, 2018
3BLQ
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BU of 3blq by Molmil
Crystal Structure of Human CDK9/cyclinT1 in Complex with ATP
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-5'-TRIPHOSPHATE, Cell division protein kinase 9, ...
著者Baumli, S, Lolli, G, Lowe, E.D, Johnson, L.N.
登録日2007-12-11
公開日2008-07-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation
Embo J., 27, 2008
3RBD
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BU of 3rbd by Molmil
Dpo4 extension ternary complex with 3'-terminal primer C base opposite the 3-methylcytosine (m3c) lesion
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ...
著者Rechkoblit, O, Patel, D.J.
登録日2011-03-29
公開日2011-06-15
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.502 Å)
主引用文献Implications for damage recognition during Dpo4-mediated mutagenic bypass of m1G and m3C lesions.
Structure, 19, 2011
3RB4
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BU of 3rb4 by Molmil
Dpo4 extension ternary complex with 3'-terminal primer G base opposite the 3-methylcytosine (m3c) lesion
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*C*CP*TP*AP*AP*CP*(ME6)P*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*CP*C)-3'), ...
著者Rechkoblit, O, Patel, D.J.
登録日2011-03-28
公開日2011-06-15
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.805 Å)
主引用文献Implications for damage recognition during Dpo4-mediated mutagenic bypass of m1G and m3C lesions.
Structure, 19, 2011
3RB6
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BU of 3rb6 by Molmil
Dpo4 extension ternary complex with 3'-terminal primer A base opposite the 3-methylcytosine (m3c) lesion
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ...
著者Rechkoblit, O, Patel, D.J.
登録日2011-03-28
公開日2011-06-15
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Implications for damage recognition during Dpo4-mediated mutagenic bypass of m1G and m3C lesions.
Structure, 19, 2011
3RBE
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BU of 3rbe by Molmil
Dpo4 extension ternary complex with 3'-terminal primer t base opposite the 3-methylcytosine (m3c) lesion
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*C*CP*TP*AP*AP*CP*(ME6)P*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*CP*C)-3'), ...
著者Rechkoblit, O, Patel, D.J.
登録日2011-03-29
公開日2011-06-15
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Implications for damage recognition during Dpo4-mediated mutagenic bypass of m1G and m3C lesions.
Structure, 19, 2011

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