5KAY
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3B3X
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![BU of 3b3x by Molmil](/molmil-images/mine/3b3x) | Crystal structure of class A beta-lactamase of Bacillus licheniformis BS3 with aminocitrate | 分子名称: | 2-(carboxymethyl)-D-aspartic acid, Beta-lactamase | 著者 | Sauvage, E, Herman, R, Kerff, F, Charlier, P. | 登録日 | 2007-10-23 | 公開日 | 2007-11-13 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | 2-Aminopropane-1,2,3-tricarboxylic acid: Synthesis and co-crystallization with the class A beta-lactamase BS3 of Bacillus licheniformis Bioorg.Med.Chem.Lett., 18, 2008
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3BMQ
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![BU of 3bmq by Molmil](/molmil-images/mine/3bmq) | Structure of Pteridine Reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with cofactor (NADP+) and inhibitor (Compound AX5) | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 6-(benzylsulfanyl)pyrimidine-2,4-diamine, ACETATE ION, ... | 著者 | Martini, V.P, Iulek, J, Hunter, W.N. | 登録日 | 2007-12-13 | 公開日 | 2008-12-16 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure-based design of pteridine reductase inhibitors targeting african sleeping sickness and the leishmaniases. J.Med.Chem., 53, 2010
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5K8O
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![BU of 5k8o by Molmil](/molmil-images/mine/5k8o) | Mn2+/5NSA-bound 5-nitroanthranilate aminohydrolase | 分子名称: | 5-nitroanthranilic acid aminohydrolase, 5-nitrosalicylic acid, MANGANESE (II) ION | 著者 | Kalyoncu, S. | 登録日 | 2016-05-30 | 公開日 | 2016-10-05 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.893 Å) | 主引用文献 | Enzymatic hydrolysis by transition-metal-dependent nucleophilic aromatic substitution. Nat.Chem.Biol., 12, 2016
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5JYK
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![BU of 5jyk by Molmil](/molmil-images/mine/5jyk) | Deg9 crystal under 289K | 分子名称: | GLYCEROL, Protease Do-like 9 | 著者 | Ouyang, M, Zhang, L.X. | 登録日 | 2016-05-14 | 公開日 | 2017-05-31 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.297 Å) | 主引用文献 | The crystal structure of Deg9 reveals a novel octameric-type HtrA protease Nat Plants, 3, 2017
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1NOM
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5JZE
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![BU of 5jze by Molmil](/molmil-images/mine/5jze) | Erve virus viral OTU domain protease in complex with mouse ISG15 | 分子名称: | CITRATE ANION, RNA-dependent RNA polymerase, Ubiquitin-like protein ISG15, ... | 著者 | Deaton, M.K, Dzimianski, J.V, Pegan, S.D. | 登録日 | 2016-05-16 | 公開日 | 2016-10-19 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | 主引用文献 | Biochemical and Structural Insights into the Preference of Nairoviral DeISGylases for Interferon-Stimulated Gene Product 15 Originating from Certain Species. J.Virol., 90, 2016
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5K14
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![BU of 5k14 by Molmil](/molmil-images/mine/5k14) | HIV-1 Reverse Transcriptase in complex with a 2,6-difluorophenyl DAPY analog | 分子名称: | 4-{[4-(2,6-difluoro-4-methoxybenzene-1-carbonyl)pyrimidin-2-yl]amino}benzonitrile, HIV-1 reverse transcriptase (isolate LW123), HIV-1 reverse transcriptase(isolate HXB2) | 著者 | Lansdon, E.B. | 登録日 | 2016-05-17 | 公開日 | 2016-06-29 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.402 Å) | 主引用文献 | Novel (2,6-difluorophenyl)(2-(phenylamino)pyrimidin-4-yl)methanones with restricted conformation as potent non-nucleoside reverse transcriptase inhibitors against HIV-1. Eur.J.Med.Chem., 122, 2016
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2ZL1
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![BU of 2zl1 by Molmil](/molmil-images/mine/2zl1) | MP1-p14 Scaffolding complex | 分子名称: | Mitogen-activated protein kinase kinase 1-interacting protein 1, Mitogen-activated protein-binding protein-interacting protein | 著者 | Schrag, J.D, Cygler, M, Munger, C, Magloire, A. | 登録日 | 2008-04-02 | 公開日 | 2008-06-24 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Molecular dynamics-solvated interaction energy studies of protein-protein interactions: the MP1-p14 scaffolding complex. J.Mol.Biol., 379, 2008
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2ZLA
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![BU of 2zla by Molmil](/molmil-images/mine/2zla) | 2-Substituted-16-ene-22-thia-1alpha,25-dihydroxy-26,27-dimethyl-19-norvitamin D3 analogs: Synthesis, biological evaluation and crystal structure | 分子名称: | (1R,2S,3R,5Z,7E)-17-{(1R)-1-[(2-ethyl-2-hydroxybutyl)sulfanyl]ethyl}-2-(2-hydroxyethoxy)-9,10-secoestra-5,7,16-triene-1,3-diol, Coactivator peptide DRIP, Vitamin D3 receptor | 著者 | Shimizu, M, Miyamoto, Y, Nakabayashi, M, Masuno, H, Ikura, T, Ito, N. | 登録日 | 2008-04-04 | 公開日 | 2008-06-24 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | 2-Substituted-16-ene-22-thia-1alpha,25-dihydroxy-26,27-dimethyl-19-norvitamin D3 analogs: Synthesis, biological evaluation, and crystal structure Bioorg.Med.Chem., 16, 2008
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1OZ9
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![BU of 1oz9 by Molmil](/molmil-images/mine/1oz9) | Crystal structure of AQ_1354, a hypothetical protein from Aquifex aeolicus | 分子名称: | Hypothetical protein AQ_1354 | 著者 | Oganesyan, V, Busso, D, Brandsen, J, Chen, S, Jancarik, J, Kim, R, Kim, S.H, Berkeley Structural Genomics Center (BSGC) | 登録日 | 2003-04-08 | 公開日 | 2003-09-23 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.894 Å) | 主引用文献 | Structure of the hypothetical protein AQ_1354 from Aquifex aeolicus. Acta Crystallogr.,Sect.D, 59, 2003
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3BBR
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5KJF
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5KKR
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![BU of 5kkr by Molmil](/molmil-images/mine/5kkr) | KSR2:MEK1 Complex Bound to the Small Molecule APS-2-79 | 分子名称: | 6,7-dimethoxy-~{N}-(2-methyl-4-phenoxy-phenyl)quinazolin-4-amine, Dual specificity mitogen-activated protein kinase kinase 1, Kinase suppressor of Ras 2 | 著者 | Dhawan, N.S, Scopton, A.P, Dar, A.C. | 登録日 | 2016-06-22 | 公開日 | 2016-08-31 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.509 Å) | 主引用文献 | Small molecule stabilization of the KSR inactive state antagonizes oncogenic Ras signalling. Nature, 537, 2016
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1MCK
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![BU of 1mck by Molmil](/molmil-images/mine/1mck) | PRINCIPLES AND PITFALLS IN DESIGNING SITE DIRECTED PEPTIDE LIGANDS | 分子名称: | IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN), PEPTIDE N-ACETYL-D-GLU-L-HIS-D-PRO-NH2 | 著者 | Edmundson, A.B, Harris, D.L, Fan, Z.-C, Guddat, L.W. | 登録日 | 1993-02-25 | 公開日 | 1994-01-31 | 最終更新日 | 2017-11-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Principles and pitfalls in designing site-directed peptide ligands. Proteins, 16, 1993
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1MCH
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![BU of 1mch by Molmil](/molmil-images/mine/1mch) | PRINCIPLES AND PITFALLS IN DESIGNING SITE DIRECTED PEPTIDE LIGANDS | 分子名称: | IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN), PEPTIDE N-ACETYL-L-GLN-D-PHE-L-HIS-D-PRO-B-ALA-B-ALA-OH | 著者 | Edmundson, A.B, Harris, D.L, Fan, Z.-C, Guddat, L.W. | 登録日 | 1993-02-25 | 公開日 | 1994-01-31 | 最終更新日 | 2017-11-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Principles and pitfalls in designing site-directed peptide ligands. Proteins, 16, 1993
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1MCQ
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![BU of 1mcq by Molmil](/molmil-images/mine/1mcq) | PRINCIPLES AND PITFALLS IN DESIGNING SITE DIRECTED PEPTIDE LIGANDS | 分子名称: | IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN), PEPTIDE N-ACETYL-L-HIS-D-PRO-NH2 | 著者 | Edmundson, A.B, Harris, D.L, Fan, Z.-C, Guddat, L.W. | 登録日 | 1993-02-25 | 公開日 | 1994-01-31 | 最終更新日 | 2017-11-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Principles and pitfalls in designing site-directed peptide ligands. Proteins, 16, 1993
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3B87
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![BU of 3b87 by Molmil](/molmil-images/mine/3b87) | Complex of T57A Substituted Droposphila LUSH protein with Butanol | 分子名称: | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, ACETATE ION, General odorant-binding protein lush | 著者 | Jones, D.N.M, Thode, A.B. | 登録日 | 2007-10-31 | 公開日 | 2008-02-05 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The role of multiple hydrogen-bonding groups in specific alcohol binding sites in proteins: insights from structural studies of LUSH. J.Mol.Biol., 376, 2008
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5J75
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![BU of 5j75 by Molmil](/molmil-images/mine/5j75) | Fluorogen Activating Protein AM2.2 in complex with ML342 | 分子名称: | N,4-dimethyl-N-{2-oxo-2-[4-(pyridin-2-yl)piperazin-1-yl]ethyl}benzene-1-sulfonamide, PHOSPHATE ION, scFv AM2.2 | 著者 | Stanfield, R.L, Wilson, I.A, Wu, Y. | 登録日 | 2016-04-05 | 公開日 | 2016-05-04 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Discovery of Small-Molecule Nonfluorescent Inhibitors of Fluorogen-Fluorogen Activating Protein Binding Pair. J Biomol Screen, 21, 2016
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3BMC
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1MCB
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![BU of 1mcb by Molmil](/molmil-images/mine/1mcb) | PRINCIPLES AND PITFALLS IN DESIGNING SITE DIRECTED PEPTIDE LIGANDS | 分子名称: | IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN), PEPTIDE N-ACETYL-L-GLN-D-PHE-L-HIS-D-PRO-OH | 著者 | Edmundson, A.B, Harris, D.L, Fan, Z.-C, Guddat, L.W. | 登録日 | 1993-02-25 | 公開日 | 1994-01-31 | 最終更新日 | 2017-11-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Principles and pitfalls in designing site-directed peptide ligands. Proteins, 16, 1993
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1MCI
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![BU of 1mci by Molmil](/molmil-images/mine/1mci) | PRINCIPLES AND PITFALLS IN DESIGNING SITE DIRECTED PEPTIDE LIGANDS | 分子名称: | IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN), PEPTIDE N-ACETYL-D-PHE-L-HIS-D-PRO-OH | 著者 | Edmundson, A.B, Harris, D.L, Fan, Z.-C, Guddat, L.W. | 登録日 | 1993-02-25 | 公開日 | 1994-01-31 | 最終更新日 | 2017-11-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Principles and pitfalls in designing site-directed peptide ligands. Proteins, 16, 1993
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1MCS
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![BU of 1mcs by Molmil](/molmil-images/mine/1mcs) | PRINCIPLES AND PITFALLS IN DESIGNING SITE DIRECTED PEPTIDE LIGANDS | 分子名称: | IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN), PEPTIDE N-ACETYL-L-GLN-D-PHE-L-HIS-D-PRO-OH | 著者 | Edmundson, A.B, Harris, D.L, Fan, Z.-C, Guddat, L.W. | 登録日 | 1993-02-25 | 公開日 | 1994-01-31 | 最終更新日 | 2017-11-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Principles and pitfalls in designing site-directed peptide ligands. Proteins, 16, 1993
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5JMX
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![BU of 5jmx by Molmil](/molmil-images/mine/5jmx) | Crystal Structure of BcII metallo-beta-lactamase in complex with DZ-305 | 分子名称: | (2Z)-3-(4-fluorophenyl)-2-sulfanylprop-2-enoic acid, GLYCEROL, Metallo-beta-lactamase type 2, ... | 著者 | Stepanovs, D, McDonough, M.A, Schofield, C.J, Zhang, D, Brem, J. | 登録日 | 2016-04-29 | 公開日 | 2017-05-24 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | 主引用文献 | Structure activity relationship studies on rhodanines and derived enethiol inhibitors of metallo-beta-lactamases. Bioorg. Med. Chem., 26, 2018
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5J8I
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![BU of 5j8i by Molmil](/molmil-images/mine/5j8i) | Crystal structure of TL11-113 bound to TAK1-TAB1 | 分子名称: | Mitogen-activated protein kinase kinase kinase 7/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 chimera, N-{2-[(5-chloro-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)oxy]phenyl}prop-2-enamide | 著者 | Gurbani, D, Westover, K.D. | 登録日 | 2016-04-07 | 公開日 | 2017-02-15 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.404 Å) | 主引用文献 | Structure-guided development of covalent TAK1 inhibitors. Bioorg. Med. Chem., 25, 2017
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