PDB: 30476 件ウェブページステータス検索Chemie searchBIRD

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7Z6F	Crystal structure of the substrate-binding protein YejA in complex with peptide fragment 分子名称: CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ... 著者 Beis, K, Qu, F. 登録日 2022-03-11 公開日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal structure of the substrate-binding protein YejA in complex with peptide fragment To Be Published
7SKW	Ab initio structure of triclinic lysozyme from electron-counted MicroED data 分子名称: Lysozyme C, NITRATE ION 著者 Martynowycz, M.W, Clabbers, M.T.B, Hattne, J, Gonen, T. 登録日 2021-10-21 公開日 2022-06-08 最終更新日 2022-06-22 実験手法 ELECTRON CRYSTALLOGRAPHY (0.87 Å) 主引用文献 Ab initio phasing macromolecular structures using electron-counted MicroED data. Nat.Methods, 19, 2022
4Q11	Crystal structure of Proteus mirabilis transcriptional regulator protein Crl at 1.95A resolution 分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Sigma factor-binding protein Crl 著者 Norel, F, Mayer, C, Saul, F.A, Haouz, A. 登録日 2014-04-02 公開日 2014-08-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural and functional features of Crl proteins and identification of conserved surface residues required for interaction with the RpoS/ sigma S subunit of RNA polymerase. Biochem.J., 463, 2014
7SJQ	Ex silico engineering of cystine-dense peptides yielding a potent bispecific T-cell engager 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cystine-dense peptide, GLYCEROL, ... 著者 Rupert, P.B, Strong, R. 登録日 2021-10-18 公開日 2022-06-08 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Ex silico engineering of cystine-dense peptides yielding a potent bispecific T cell engager. Sci Transl Med, 14, 2022
7Z68	Pseudomonas aeruginosa Elastase in complex with a Thiol based inhibitor (R-and S-configured) 分子名称: (2~{R})-~{N}-[4-[(2~{S},3~{R},4~{S},5~{R},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]sulfanylphenyl]-3-phenyl-2-sulfanyl-propanamide, CALCIUM ION, GLYCEROL, ... 著者 Klein, A, Hirsch, A. 登録日 2022-03-11 公開日 2023-09-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Dual inhibitors of Pseudomonas aeruginosa virulence factors LecA and LasB To Be Published
7Z8Z	Crystal structure of the MEILB2-BRME1 2:2 core complex 分子名称: Break repair meiotic recombinase recruitment factor 1, Heat shock factor 2-binding protein 著者 Gurusaran, M, Davies, O.R. 登録日 2022-03-19 公開日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 MEILB2-BRME1 acts as a DNA clamp upon dimerisation induced by BRCA2-binding in meiotic recombination. To Be Published
7SKX	Ab initio structure of proteinase K from electron-counted MicroED data 分子名称: 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, CALCIUM ION, Proteinase K 著者 Martynowycz, M.W, Clabbers, M.T.B, Hattne, J, Gonen, T. 登録日 2021-10-21 公開日 2022-06-08 最終更新日 2022-06-22 実験手法 ELECTRON CRYSTALLOGRAPHY (1.5 Å) 主引用文献 Ab initio phasing macromolecular structures using electron-counted MicroED data. Nat.Methods, 19, 2022
7SG5	Structure of PfCSP peptide 21 with antibody CIS43_Var2 分子名称: CIS43_Var2 Fab Heavy chain, CIS43_Var2 Fab Light chain, GLYCEROL, ... 著者 Tripathi, P, Kwong, P.D. 登録日 2021-10-05 公開日 2022-06-22 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Highly protective antimalarial antibodies via precision library generation and yeast display screening. J.Exp.Med., 219, 2022
7SG6	Structure of PfCSP peptide 21 with antibody CIS43_Var10 分子名称: CIS43_Var10 Fab Heavy chain, CIS43_Var10 Fab Light chain, GLYCEROL, ... 著者 Tripathi, P, Kwong, P.D. 登録日 2021-10-05 公開日 2022-06-22 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Highly protective antimalarial antibodies via precision library generation and yeast display screening. J.Exp.Med., 219, 2022
7ZAO	Structure of BPP43_05035 of Brachyspira pilosicoli 分子名称: MAGNESIUM ION, Sialidase (Neuraminidase) family protein-like protein 著者 Rajan, A, Gallego, P, Pelaseyed, T. 登録日 2022-03-22 公開日 2023-10-11 最終更新日 2024-04-24 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 BPP43_05035 is a Brachyspira pilosicoli cell surface adhesin that weakens the integrity of the epithelial barrier during infection Biorxiv, 2024
7RWW	Crystal structure of a Zn-bound RIDC1 variant 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Kakkis, A, Golub, E. 登録日 2021-08-20 公開日 2022-06-29 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Redox- and metal-directed structural diversification in designed metalloprotein assemblies. Chem.Commun.(Camb.), 58, 2022
7S6H	Human PARP1 deltaV687-E688 bound to NAD+ analog EB-47 and to a DNA double strand break. 分子名称: 1,2-ETHANEDIOL, 2-[4-[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]carbonylpiperazin-1-yl]-N-(1-oxidanylidene-2,3-dihydroisoindol-4-yl)ethanamide, DNA (5'-D(*CP*GP*AP*CP*G)-3'), ... 著者 Rouleau-Turcotte, E, Pascal, J.M. 登録日 2021-09-14 公開日 2022-06-29 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Captured snapshots of PARP1 in the active state reveal the mechanics of PARP1 allostery. Mol.Cell, 82, 2022
7ZET	Crystal structure of human Clusterin, crystal form I 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Clusterin, ... 著者 Yuste-Checa, P, Bracher, A, Hartl, F.U. 登録日 2022-03-31 公開日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of human Clusterin, crystal form I To be published
7RWU	Crystal structure of Ni-bound RIDC1 variant in the presence of reductant 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, HEME C, ... 著者 Kakkis, A, Golub, E. 登録日 2021-08-20 公開日 2022-06-29 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Redox- and metal-directed structural diversification in designed metalloprotein assemblies. Chem.Commun.(Camb.), 58, 2022
7S81	Structure of human PARP1 domains (Zn1, Zn3, WGR, HD) bound to a DNA double strand break. 分子名称: DNA (5'-D(*AP*TP*GP*CP*GP*GP*CP*CP*GP*CP*AP*T)-3'), Poly [ADP-ribose] polymerase 1, ZINC ION 著者 Rouleau-Turcotte, E, Pascal, J.M. 登録日 2021-09-17 公開日 2022-06-29 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Captured snapshots of PARP1 in the active state reveal the mechanics of PARP1 allostery. Mol.Cell, 82, 2022
7ZEU	Crystal structure of human Clusterin, crystal form II 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Clusterin 著者 Yuste-Checa, P, Bracher, A, Hartl, F.U. 登録日 2022-03-31 公開日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Crystal structure of human Clusterin, crystal form II To be published
7RWN	Crystal Structure of BPTF bromodomain in complex with 4-chloro-5-{4-[(dimethylamino)methyl]anilino}-2-methylpyridazin-3(2H)-one 分子名称: 1,2-ETHANEDIOL, 4-chloro-5-{4-[(dimethylamino)methyl]anilino}-2-methylpyridazin-3(2H)-one, Nucleosome-remodeling factor subunit BPTF 著者 Zahid, H, Buchholz, C, Johnson, J.A, Shi, K, Aihara, H, Pomerantz, W.C.K. 登録日 2021-08-20 公開日 2022-08-24 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.39 Å) 主引用文献 New Design Rules for Developing Potent Cell-Active Inhibitors of the Nucleosome Remodeling Factor (NURF) via BPTF Bromodomain Inhibition. J.Med.Chem., 64, 2021
7RUQ	Structure of the human GIGYF1-TNRC6C complex 分子名称: GRB10-interacting GYF protein 1, Trinucleotide repeat-containing gene 6C protein 著者 Sobti, M, Mead, B.J, Igreja, C, Stewart, A.G, Christie, M. 登録日 2021-08-18 公開日 2022-08-24 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Molecular basis for GIGYF-TNRC6 complex assembly. Rna, 29, 2023
7RV5	Crystal structure of the BCL6 BTB domain in complex with OICR-9287 分子名称: 2-[2-(4-benzylpiperidin-1-yl)-4-oxo-3,4-dihydro-7H-pyrrolo[2,3-d]pyrimidin-7-yl]-N-(3-chloropyridin-4-yl)acetamide, Isoform 2 of B-cell lymphoma 6 protein 著者 Kuntz, D.A, Prive, G.G. 登録日 2021-08-18 公開日 2022-08-24 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Structure of the BCL6 BTB domain To Be Published
7SKU	Nipah virus matrix protein in complex with PI(4,5)P2 分子名称: Matrix protein, SULFATE ION, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate 著者 Norris, M.J, Saphire, E.O. 登録日 2021-10-21 公開日 2022-08-24 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.117 Å) 主引用文献 Measles and Nipah virus assembly: Specific lipid binding drives matrix polymerization. Sci Adv, 8, 2022
7SKS	Crystal structure of measles virus matrix protein 分子名称: Matrix protein 著者 Norris, M.J, Saphire, E.O. 登録日 2021-10-21 公開日 2022-08-24 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.541 Å) 主引用文献 Measles and Nipah virus assembly: Specific lipid binding drives matrix polymerization. Sci Adv, 8, 2022
7SMD	p107 pocket domain complexed with EID1 peptide 分子名称: EP300-interacting inhibitor of differentiation 1, Retinoblastoma-like protein 1, SULFATE ION 著者 Putta, S, Fernandez, S.M, Tripathi, S.M, Muller, G.A, Rubin, S.M. 登録日 2021-10-25 公開日 2022-06-29 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structural basis for tunable affinity and specificity of LxCxE-dependent protein interactions with the retinoblastoma protein family. Structure, 30, 2022
7RWE	Crystal structure of CDK2 liganded with compound GPHR787 分子名称: 5-nitro-2-[(3-phenylpropyl)amino]benzoic acid, Cyclin-dependent kinase 2 著者 Sun, L, Schonbrunn, E. 登録日 2021-08-19 公開日 2022-08-24 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 Screening through Lead Optimization of High Affinity, Allosteric Cyclin-Dependent Kinase 2 (CDK2) Inhibitors as Male Contraceptives That Reduce Sperm Counts in Mice. J.Med.Chem., 66, 2023
7S6M	Human PARP1 deltaV687-E688 bound to a DNA double strand break. 分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*CP*GP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*CP*G)-3'), ... 著者 Rouleau-Turcotte, E, Pascal, J.M. 登録日 2021-09-14 公開日 2022-06-29 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Captured snapshots of PARP1 in the active state reveal the mechanics of PARP1 allostery. Mol.Cell, 82, 2022
7YPR	Structural basis of a superoxide dismutase from a tardigrade, Ramazzottius varieornatus strain YOKOZUNA-1. 分子名称: COPPER (II) ION, POTASSIUM ION, Superoxide dismutase [Cu-Zn], ... 著者 Sim, K.-S, Fukuda, Y, Inoue, T. 登録日 2022-08-04 公開日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.101 Å) 主引用文献 Structure of a superoxide dismutase from a tardigrade: Ramazzottius varieornatus strain YOKOZUNA-1. Acta Crystallogr.,Sect.F, 79, 2023

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