7Q8V
| Crystal structure of TTBK1 in complex with VNG2.73 (compound 42) | 分子名称: | PHOSPHATE ION, Tau-tubulin kinase 1, ~{N}-[4-(2-chloranylphenoxy)phenyl]-7~{H}-pyrrolo[2,3-d]pyrimidin-4-amine | 著者 | Chaikuad, A, Nozal, V, Martinez, A, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2021-11-11 | 公開日 | 2022-03-09 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | 主引用文献 | TDP-43 Modulation by Tau-Tubulin Kinase 1 Inhibitors: A New Avenue for Future Amyotrophic Lateral Sclerosis Therapy. J.Med.Chem., 65, 2022
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7Q8Y
| Crystal structure of TTBK2 in complex with VNG2.73 (compound 42) | 分子名称: | PHOSPHATE ION, Tau-tubulin kinase 2, ~{N}-[4-(2-chloranylphenoxy)phenyl]-7~{H}-pyrrolo[2,3-d]pyrimidin-4-amine | 著者 | Chaikuad, A, Nozal, V, Martinez, A, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2021-11-11 | 公開日 | 2022-03-09 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | TDP-43 Modulation by Tau-Tubulin Kinase 1 Inhibitors: A New Avenue for Future Amyotrophic Lateral Sclerosis Therapy. J.Med.Chem., 65, 2022
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7Q8Z
| Crystal structure of TTBK2 in complex with VNG1.33 (compound 27) | 分子名称: | PHOSPHATE ION, Tau-tubulin kinase 2, ~{N}-(4-phenoxyphenyl)-7~{H}-pyrrolo[2,3-d]pyrimidin-4-amine | 著者 | Chaikuad, A, Nozal, V, Martinez, A, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2021-11-11 | 公開日 | 2022-03-09 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | TDP-43 Modulation by Tau-Tubulin Kinase 1 Inhibitors: A New Avenue for Future Amyotrophic Lateral Sclerosis Therapy. J.Med.Chem., 65, 2022
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7Q8W
| Crystal structure of TTBK1 in complex with VNG1.35 (compound 23) | 分子名称: | 1,2-ETHANEDIOL, PHOSPHATE ION, Tau-tubulin kinase 1, ... | 著者 | Chaikuad, A, Nozal, V, Martinez, A, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2021-11-11 | 公開日 | 2022-03-09 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | TDP-43 Modulation by Tau-Tubulin Kinase 1 Inhibitors: A New Avenue for Future Amyotrophic Lateral Sclerosis Therapy. J.Med.Chem., 65, 2022
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7Q90
| Crystal structure of TTBK2 in complex with VNG1.63 (compound 32) | 分子名称: | PHOSPHATE ION, Tau-tubulin kinase 2, ~{N}-[4-(4-methoxyphenoxy)phenyl]-7~{H}-pyrrolo[2,3-d]pyrimidin-4-amine | 著者 | Chaikuad, A, Nozal, V, Martinez, A, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2021-11-11 | 公開日 | 2022-03-09 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | TDP-43 Modulation by Tau-Tubulin Kinase 1 Inhibitors: A New Avenue for Future Amyotrophic Lateral Sclerosis Therapy. J.Med.Chem., 65, 2022
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7Q8B
| Leishmania major actin filament in ADP-Pi state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, MAGNESIUM ION, ... | 著者 | Kotila, T, Muniyandi, S, Lappalainen, P, Huiskonen, J.T. | 登録日 | 2021-11-11 | 公開日 | 2022-05-18 | 最終更新日 | 2022-06-29 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural basis of rapid actin dynamics in the evolutionarily divergent Leishmania parasite. Nat Commun, 13, 2022
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7Q8C
| Leishmania major actin filament in ADP-state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, MAGNESIUM ION | 著者 | Kotila, T, Muniyandi, S, Lappalainen, P, Huiskonen, J.T. | 登録日 | 2021-11-11 | 公開日 | 2022-05-18 | 最終更新日 | 2022-06-29 | 実験手法 | ELECTRON MICROSCOPY (2.72 Å) | 主引用文献 | Structural basis of rapid actin dynamics in the evolutionarily divergent Leishmania parasite. Nat Commun, 13, 2022
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7Q8S
| Leishmania major ADP-actin filament decorated with Leishmania major cofilin | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADF/Cofilin, Actin, ... | 著者 | Kotila, T, Muniyandi, S, Lappalainen, P, Huiskonen, J.T. | 登録日 | 2021-11-11 | 公開日 | 2022-05-18 | 最終更新日 | 2022-06-29 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural basis of rapid actin dynamics in the evolutionarily divergent Leishmania parasite. Nat Commun, 13, 2022
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7VWC
| Cryo-EM structure of human very long-chain fatty acid ABC transporter ABCD1 | 分子名称: | Peroxisomal Membrane Protein related,ATP-binding cassette sub-family D member 1, [(2R)-3-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-2-oxidanyl-propyl] octadecanoate | 著者 | Chen, Z.P, Xu, D, Wang, L, Mao, Y.X, Yang, L, Cheng, M.T, Hou, W.T, Chen, Y.X, Zhou, C.Z. | 登録日 | 2021-11-10 | 公開日 | 2022-05-18 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.53 Å) | 主引用文献 | Structural basis of substrate recognition and translocation by human very long-chain fatty acid transporter ABCD1. Nat Commun, 13, 2022
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7SSB
| Co-structure of PKG1 regulatory domain with compound 33 | 分子名称: | 4-({(2S,3S)-3-[(1S)-1-(3,5-dichlorophenyl)-2-hydroxyethoxy]-2-phenylpiperidin-1-yl}methyl)-3-nitrobenzoic acid, cGMP-dependent protein kinase 1 | 著者 | Fischmann, T.O. | 登録日 | 2021-11-10 | 公開日 | 2022-08-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Optimization and Mechanistic Investigations of Novel Allosteric Activators of PKG1 alpha. J.Med.Chem., 65, 2022
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7SSA
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7Q89
| OleP mutant G92W in complex with 6DEB | 分子名称: | 6-DEOXYERYTHRONOLIDE B, Cytochrome P-450, FORMIC ACID, ... | 著者 | Savino, C, Montemiglio, L.C, Vallone, B, Exertier, C, Freda, I, Gugole, E. | 登録日 | 2021-11-10 | 公開日 | 2022-01-26 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Point Mutations at a Key Site Alter the Cytochrome P450 OleP Structural Dynamics. Biomolecules, 12, 2021
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7Q8A
| Crystal structure of tandem domain RRM1-2 of FUBP-interacting repressor (FIR) bound to FUSE ssDNA fragment | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(P*GP*T)-3'), Poly(U)-binding-splicing factor PUF60, ... | 著者 | Ni, X, Joerger, A.C, Chaikuad, A, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2021-11-10 | 公開日 | 2022-11-09 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Crystal structure of tandem domain RRM1-2 of FIR bound to FUSE ssDNA fragment To Be Published
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7VW7
| Crystal structure of the 2 ADP-AlF4-bound V1 complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | 著者 | Suzuki, K, Shekhar, M, Gupta, C, Singharoy, A, Murata, T. | 登録日 | 2021-11-09 | 公開日 | 2022-06-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.818 Å) | 主引用文献 | Revealing a Hidden Intermediate of Rotatory Catalysis with X-ray Crystallography and Molecular Simulations. Acs Cent.Sci., 8, 2022
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7Q6X
| OleP mutant S240Y in complex with 6DEB | 分子名称: | 6-DEOXYERYTHRONOLIDE B, Cytochrome P-450, FORMIC ACID, ... | 著者 | Savino, C, Montemiglio, L.C, Vallone, B, Exertier, C, Freda, I, Gugole, E. | 登録日 | 2021-11-09 | 公開日 | 2022-01-26 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Point Mutations at a Key Site Alter the Cytochrome P450 OleP Structural Dynamics. Biomolecules, 12, 2021
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7Q6R
| OleP mutant E89Y in complex with 6DEB | 分子名称: | 6-DEOXYERYTHRONOLIDE B, Cytochrome P-450, FORMIC ACID, ... | 著者 | Savino, C, Montemiglio, L.C, Vallone, B, Exertier, C, Freda, I, Gugole, E. | 登録日 | 2021-11-09 | 公開日 | 2022-01-26 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | 主引用文献 | Point Mutations at a Key Site Alter the Cytochrome P450 OleP Structural Dynamics. Biomolecules, 12, 2021
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7VVY
| TRA module of NuA4 | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin, Actin-related protein 4, ... | 著者 | Chen, Z, Qu, K. | 登録日 | 2021-11-09 | 公開日 | 2022-08-10 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structure of the NuA4 acetyltransferase complex bound to the nucleosome. Nature, 610, 2022
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7VVZ
| NuA4 bound to the nucleosome | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin, Actin-related protein 4, ... | 著者 | Qu, K, Chen, Z. | 登録日 | 2021-11-09 | 公開日 | 2022-08-10 | 最終更新日 | 2022-11-16 | 実験手法 | ELECTRON MICROSCOPY (8.8 Å) | 主引用文献 | Structure of the NuA4 acetyltransferase complex bound to the nucleosome. Nature, 610, 2022
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7Q7A
| Room temperature structure of RNase A at 120 MPa helium gas pressure in a sapphire capillary | 分子名称: | CHLORIDE ION, Ribonuclease pancreatic, SODIUM ION, ... | 著者 | Lieske, J, Guenther, S, Saouane, S, Meents, A. | 登録日 | 2021-11-09 | 公開日 | 2022-11-16 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | 主引用文献 | Fixed-target high-pressure macromolecular crystallography To Be Published
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7Q7C
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7Q77
| Room temperature structure of RNase A at 50 MPa helium gas pressure in a sapphire capillary | 分子名称: | CHLORIDE ION, Ribonuclease pancreatic, SODIUM ION, ... | 著者 | Lieske, J, Guenther, S, Saouane, S, Meents, A. | 登録日 | 2021-11-09 | 公開日 | 2022-11-16 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Fixed-target high-pressure macromolecular crystallography To Be Published
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7VW4
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7Q76
| Room temperature structure of RNase A at 22 MPa helium gas pressure in a sapphire capillary | 分子名称: | CHLORIDE ION, Ribonuclease pancreatic, SODIUM ION, ... | 著者 | Lieske, J, Guenther, S, Saouane, S, Meents, A. | 登録日 | 2021-11-09 | 公開日 | 2022-11-16 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Fixed-target high-pressure macromolecular crystallography To Be Published
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7Q79
| Room temperature structure of RNase A at 100 MPa helium gas pressure in a sapphire capillary | 分子名称: | CHLORIDE ION, Ribonuclease pancreatic, SODIUM ION, ... | 著者 | Lieske, J, Guenther, S, Saouane, S, Meents, A. | 登録日 | 2021-11-09 | 公開日 | 2022-11-16 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Fixed-target high-pressure macromolecular crystallography To Be Published
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7Q75
| Room temperature structure of RNase A at atmospheric pressure | 分子名称: | CHLORIDE ION, Ribonuclease pancreatic, SODIUM ION, ... | 著者 | Lieske, J, Guenther, S, Saouane, S, Meents, A. | 登録日 | 2021-11-09 | 公開日 | 2022-11-16 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Fixed-target high-pressure macromolecular crystallography To Be Published
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