PDB: 245011 件ウェブページステータス検索Chemie searchBIRD

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6LEI	Structure of D-carbamoylase from Nitratireductor indicus 分子名称: 1,2-ETHANEDIOL, N-carbamoyl-D-amino-acid hydrolase 著者 Ni, Y, Liu, Y.F, Xu, G.C. 登録日 2019-11-25 公開日 2020-10-28 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure-Guided Engineering of D-Carbamoylase Reveals a Key Loop at Substrate Entrance Tunnel Acs Catalysis, 10, 2020
7C3Y	Crystal structure of the N-terminal domain of human MdmX protein in complex with Nutlin3a 分子名称: 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, 4-({(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazol-1-yl}carbonyl)piperazin-2-one, Protein Mdm4 著者 Su, Z.D, Cheng, X.Y, Zhang, B.L, Kuang, Z.K, Yang, J, Li, Z.C, Yu, J.P, Zhao, Z.T, Cao, C.Z. 登録日 2020-05-14 公開日 2020-06-17 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.632 Å) 主引用文献 Crystal structure of the N-terminal domain of human MdmX protein in complex with Nutlin3a To Be Published
6LFX	Crystal structure of PCB4scFv(hN56D) in complex with PCB#77 分子名称: 1,2-bis(chloranyl)-4-(3-chloranyl-4-methoxy-phenyl)benzene, PCB4scFv(hN56D) 著者 Nakamura, T, Yamagata, Y, Morioka, H. 登録日 2019-12-03 公開日 2020-12-09 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.43 Å) 主引用文献 Crystal structure of PCB4scFv(hN56D) in complex with PCB#77 To Be Published
5CTI	Crystal structure of the type IX collagen NC2 hetero-trimerization domain with a guest fragment a2a1a1 of type I collagen (native form) 分子名称: Collagen alpha-1(I) chain,Collagen alpha-1(IX) chain, Collagen alpha-1(I) chain,Collagen alpha-3(IX) chain, Collagen alpha-2(I) chain,Collagen alpha-2(IX) chain, ... 著者 Boudko, S.P, Bachinger, H.P. 登録日 2015-07-24 公開日 2016-08-03 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.8994 Å) 主引用文献 Structural insight for chain selection and stagger control in collagen. Sci Rep, 6, 2016
1BJR	COMPLEX FORMED BETWEEN PROTEOLYTICALLY GENERATED LACTOFERRIN FRAGMENT AND PROTEINASE K 分子名称: CALCIUM ION, LACTOFERRIN, PROTEINASE K 著者 Singh, T.P, Sharma, S, Karthikeyan, S, Betzel, C, Bhatia, K.L. 登録日 1998-06-27 公開日 1998-11-04 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.44 Å) 主引用文献 Crystal structure of a complex formed between proteolytically-generated lactoferrin fragment and proteinase K. Proteins, 33, 1998
4NCY	In situ trypsin crystallized on a MiTeGen micromesh with imidazole ligand 分子名称: 1,2-ETHANEDIOL, BENZAMIDINE, CALCIUM ION, ... 著者 Yin, X, Scalia, A, Leroy, L, Cuttitta, C.M, Polizzo, G.M, Ericson, D.L, Roessler, C.G, Campos, O, Agarwal, R, Allaire, M, Orville, A.M, Jackimowicz, R, Ma, M.Y, Sweet, R.M, Soares, A.S. 登録日 2013-10-25 公開日 2014-04-09 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Hitting the target: fragment screening with acoustic in situ co-crystallization of proteins plus fragment libraries on pin-mounted data-collection micromeshes. Acta Crystallogr.,Sect.D, 70, 2014
4WY1	Crystal structure of human BACE-1 bound to Compound 24B 分子名称: (4aR,8aS)-8a-(2,4-difluorophenyl)-4,4a,5,6,8,8a-hexahydropyrano[3,4-d][1,3]thiazin-2-amine, Beta-secretase 1 著者 Vajdos, F.F, Parris, K. 登録日 2014-11-14 公開日 2015-03-04 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Discovery of a Series of Efficient, Centrally Efficacious BACE1 Inhibitors through Structure-Based Drug Design. J.Med.Chem., 58, 2015
2A7U	NMR solution structure of the E.coli F-ATPase delta subunit N-terminal domain in complex with alpha subunit N-terminal 22 residues 分子名称: ATP synthase alpha chain, ATP synthase delta chain 著者 Wilkens, S, Borchardt, D, Weber, J, Senior, A.E. 登録日 2005-07-06 公開日 2005-10-11 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Structural Characterization of the Interaction of the delta and alpha Subunits of the Escherichia coli F(1)F(0)-ATP Synthase by NMR Spectroscopy Biochemistry, 44, 2005
7EXK	An AA9 LPMO of Ceriporiopsis subvermispora 分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Nguyen, H, Kondo, K, Nagata, T, Katahira, M, Mikami, B. 登録日 2021-05-27 公開日 2022-05-04 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Functional and Structural Characterizations of Lytic Polysaccharide Monooxygenase, Which Cooperates Synergistically with Cellulases, from Ceriporiopsis subvermispora. Acs Sustain Chem Eng, 10, 2022
6KYJ	Hybrid-Rubisco (rice RbcL and sorghum RbcS) in complex with sulfate ions 分子名称: GLYCEROL, Ribulose bisphosphate carboxylase large chain, Ribulose bisphosphate carboxylase small chain, ... 著者 Matsumura, H, Yoshizawa, T, Tanaka, S, Yoshikawa, H. 登録日 2019-09-19 公開日 2020-09-16 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Hybrid Rubisco with Complete Replacement of Rice Rubisco Small Subunits by Sorghum Counterparts Confers C 4 Plant-like High Catalytic Activity. Mol Plant, 13, 2020
4X7E	Crystal structure of norovirus GII.10 P domain in complex with Nano-85 分子名称: 1,2-ETHANEDIOL, ACETATE ION, Capsid protein, ... 著者 Hansman, G.H, Koromyslova, A.D. 登録日 2014-12-09 公開日 2014-12-31 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Nanobody binding to a conserved epitope promotes norovirus particle disassembly. J.Virol., 89, 2015
6KZN	Crystal Structure Of VIM-2 Metallo-beta-lactamase In Complex With Inhibitor X2 分子名称: 2,5-diethyl-1-methyl-4-sulfamoyl-pyrrole-3-carboxylic acid, Beta-lactamase class B VIM-2, FORMIC ACID, ... 著者 Wachino, J. 登録日 2019-09-24 公開日 2020-02-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Sulfamoyl Heteroarylcarboxylic Acids as Promising Metallo-beta-Lactamase Inhibitors for Controlling Bacterial Carbapenem Resistance. Mbio, 11, 2020
1BRS	PROTEIN-PROTEIN RECOGNITION: CRYSTAL STRUCTURAL ANALYSIS OF A BARNASE-BARSTAR COMPLEX AT 2.0-A RESOLUTION 分子名称: BARNASE, BARSTAR 著者 Buckle, A.M, Schreiber, G, Fersht, A.R. 登録日 1994-03-11 公開日 1994-06-22 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Protein-protein recognition: crystal structural analysis of a barnase-barstar complex at 2.0-A resolution. Biochemistry, 33, 1994
8JUW	Human ATAD2 Walker B mutant-H3/H4K5Q complex, ATP state 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATPase family AAA domain-containing protein 2 著者 Cho, C, Song, J. 登録日 2023-06-27 公開日 2023-10-18 最終更新日 2025-06-18 実験手法 ELECTRON MICROSCOPY (3.79 Å) 主引用文献 Structure of the human ATAD2 AAA+ histone chaperone reveals mechanism of regulation and inter-subunit communication. Commun Biol, 6, 2023
1BTX	Episelection: Novel Ki ~Nanomolar Inhibitors of Serine Proteases Selected by Binding or Chemistry on an Enzyme Surface 分子名称: BETA-TRYPSIN, CALCIUM ION, N-(tert-butoxycarbonyl)-L-alanyl-N-[(1S)-5-amino-1-(diethoxyboranyl)pentyl]-L-valinamide 著者 Stroud, R.M, Katz, B.A, Finer-Moore, J. 登録日 1995-05-17 公開日 1995-10-15 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Episelection: novel Ki approximately nanomolar inhibitors of serine proteases selected by binding or chemistry on an enzyme surface. Biochemistry, 34, 1995
4X00	X-ray crystal structure of a putative aryl esterase from Burkholderia cenocepacia 分子名称: 1,2-ETHANEDIOL, FLUORIDE ION, GLYCEROL, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2014-11-20 公開日 2014-12-03 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 X-ray crystal structure of a putative aryl esterase from Burkholderia cenocepacia to be published
6F4W	Crystal structure of H. pylori purine nucleoside phosphorylase in complex with formycin A 分子名称: (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, Purine nucleoside phosphorylase DeoD-type 著者 Stefanic, Z. 登録日 2017-11-30 公開日 2018-02-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.293 Å) 主引用文献 Helicobacter pylori purine nucleoside phosphorylase shows new distribution patterns of open and closed active site conformations and unusual biochemical features. FEBS J., 285, 2018
7COV	Potato D-enzyme, native (substrate free) 分子名称: 4-alpha-glucanotransferase, chloroplastic/amyloplastic, CALCIUM ION, ... 著者 Unno, H, Imamura, K. 登録日 2020-08-05 公開日 2020-08-26 最終更新日 2025-03-12 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural analysis and reaction mechanism of the disproportionating enzyme (D-enzyme) from potato. Protein Sci., 29, 2020
6UOL	Y271G DNA polymerase beta substrate complex with a templating cytosine and incoming rGTP 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... 著者 Smith, M.R, Freudenthal, B.D. 登録日 2019-10-15 公開日 2020-01-08 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.936 Å) 主引用文献 Molecular and structural characterization of oxidized ribonucleotide insertion into DNA by human DNA polymerase beta. J.Biol.Chem., 295, 2020
4X0V	Structure of a GH5 family lichenase from Caldicellulosiruptor sp. F32 分子名称: Beta-1,3-1,4-glucanase 著者 Meng, D, Liu, X, Wang, X, Li, F, Feng, Y. 登録日 2014-11-24 公開日 2015-11-25 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.798 Å) 主引用文献 Structural Insights into the Substrate Specificity of a Glycoside Hydrolase Family 5 Lichenase from Caldicellulosiruptor sp. F32 Biochem. J., 2017
4NG3	Crystal structure of 5-carboxyvanillate decarboxylase from Sphingomonas paucimobilis complexed with 4-Hydroxy-3-methoxy-5-nitrobenzoic acid 分子名称: 1,2-ETHANEDIOL, 4-hydroxy-3-methoxy-5-nitrobenzoic acid, 5-carboxyvanillate decarboxylase, ... 著者 Fedorov, A.A, Fedorov, E.V, Vladimirova, A, Raushel, F.M, Almo, S.C. 登録日 2013-11-01 公開日 2013-11-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.751 Å) 主引用文献 Crystal structure of 5-carboxyvanillate decarboxylase from Sphingomonas paucimobilis complexed with 4-Hydroxy-3-methoxy-5-nitrobenzoic acid To be Published
5OA3	Human 40S-eIF2D-re-initiation complex 分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Weisser, M, Schaefer, T, Leibundgut, M, Boehringer, D, Aylett, C.H.S, Ban, N. 登録日 2017-06-20 公開日 2017-08-09 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Structural and Functional Insights into Human Re-initiation Complexes. Mol. Cell, 67, 2017
6L8L	C-Src in complex with ibrutinib 分子名称: 1-{(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl}prop-2-en-1-one, Proto-oncogene tyrosine-protein kinase Src 著者 Guo, M, Dai, S, Chen, L, Chen, Y. 登録日 2019-11-06 公開日 2020-11-11 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.888 Å) 主引用文献 Characterization of ibrutinib as a non-covalent inhibitor of SRC-family kinases. Bioorg.Med.Chem.Lett., 34, 2020
5VPX	I38T mutant of 2009 H1N1 PA Endonuclease in complex with RO-7 分子名称: 1-[(11S)-6,11-dihydrodibenzo[b,e]thiepin-11-yl]-5-hydroxy-3-[(2R)-1,1,1-trifluoropropan-2-yl]-2,3-dihydro-1H-pyrido[2,1-f][1,2,4]triazine-4,6-dione, MANGANESE (II) ION, Polymerase acidic protein, ... 著者 Kumar, G, White, S.W. 登録日 2017-05-06 公開日 2018-04-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.303 Å) 主引用文献 Identification of the I38T PA Substitution as a Resistance Marker for Next-Generation Influenza Virus Endonuclease Inhibitors. MBio, 9, 2018
4NMM	Crystal Structure of a G12C Oncogenic Variant of Human KRas Bound to a Novel GDP Competitive Covalent Inhibitor 分子名称: 5'-O-[(S)-{[(S)-[2-(acetylamino)ethoxy](hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]guanosine, GTPase KRas, MAGNESIUM ION 著者 Hunter, J.C, Gurbani, D, Lim, S.M, Westover, K.D. 登録日 2013-11-15 公開日 2014-06-04 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 In situ selectivity profiling and crystal structure of SML-8-73-1, an active site inhibitor of oncogenic K-Ras G12C. Proc.Natl.Acad.Sci.USA, 111, 2014

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