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8K0G
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BU of 8k0g by Molmil
Cryo-EM structure of human 26S RP (Ed state) bound to K11/K48-branched ubiquitin (Ub) chain composed of four Ub.
分子名称: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ...
著者Hsu, S.T.D, Draczkowski, P, Wang, Y.S.
登録日2023-07-09
公開日2025-01-22
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Cryo-EM structure of human 26S proteasomal RP subcomplex bound with branched Ub chain.
To Be Published
1Z9C
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BU of 1z9c by Molmil
Crystal structure of OhrR bound to the ohrA promoter: Structure of MarR family protein with operator DNA
分子名称: DNA (29-MER), Organic hydroperoxide resistance transcriptional regulator
著者Hong, M, Fuangthong, M, Helmann, J.D, Brennan, R.G.
登録日2005-04-01
公開日2005-10-25
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Structure of an OhrR-ohrA Operator Complex Reveals the DNA Binding Mechanism of the MarR Family.
Mol.Cell, 20, 2005
5L4G
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BU of 5l4g by Molmil
The human 26S proteasome at 3.9 A
分子名称: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ...
著者Schweitzer, A, Aufderheide, A, Rudack, T, Beck, F.
登録日2016-05-25
公開日2016-09-07
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structure of the human 26S proteasome at a resolution of 3.9 angstrom.
Proc.Natl.Acad.Sci.USA, 113, 2016
5OAF
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BU of 5oaf by Molmil
Human Rvb1/Rvb2 heterohexamer in INO80 complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2
著者Aramayo, R.J, Bythell-Douglas, R, Ayala, R, Willhoft, O, Wigley, D, Zhang, X.
登録日2017-06-21
公開日2017-12-13
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.06 Å)
主引用文献Cryo-EM structures of the human INO80 chromatin-remodeling complex.
Nat. Struct. Mol. Biol., 25, 2018
5B33
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BU of 5b33 by Molmil
The crystal structure of the H2AZ nucleosome with H3.3.
分子名称: DNA (146-MER), Histone H2A.Z, Histone H2B type 1-J, ...
著者Horikoshi, N, Taguchi, H, Arimura, Y, Kurumizaka, H.
登録日2016-02-08
公開日2016-08-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.925 Å)
主引用文献Crystal structures of heterotypic nucleosomes containing histones H2A.Z and H2A.
Open Biology, 6, 2016
6YOS
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BU of 6yos by Molmil
Binary complex of 14-3-3 zeta with Glucocorticoid Receptor (GR) pT524 pS617 peptide
分子名称: 14-3-3 protein zeta/delta, Glucocorticoid receptor,Glucocorticoid receptor
著者Munier, C.C, Edman, K, Perry, M.W.D, Ottmann, C.
登録日2020-04-15
公開日2021-03-24
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Glucocorticoid receptor Thr524 phosphorylation by MINK1 induces interactions with 14-3-3 protein regulators.
J.Biol.Chem., 296, 2021
6YO8
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BU of 6yo8 by Molmil
Binary complex of 14-3-3 zeta with Glucocorticoid Receptor (GR) pT524 peptide
分子名称: 14-3-3 protein zeta/delta, Glucocorticoid receptor
著者Munier, C.C, Edman, K, Perry, M.W.D, Ottmann, C.
登録日2020-04-14
公開日2021-03-24
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Glucocorticoid receptor Thr524 phosphorylation by MINK1 induces interactions with 14-3-3 protein regulators.
J.Biol.Chem., 296, 2021
6YMO
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BU of 6ymo by Molmil
Binary complex of 14-3-3 zeta with Glucocorticoid Receptor (GR) pS617 peptide
分子名称: 14-3-3 protein zeta/delta, 2-HYDROXYBENZOIC ACID, Glucocorticoid receptor, ...
著者Munier, C.C, Edman, K, Perry, M.W.D, Ottmann, C.
登録日2020-04-09
公開日2021-03-24
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Glucocorticoid receptor Thr524 phosphorylation by MINK1 induces interactions with 14-3-3 protein regulators.
J.Biol.Chem., 296, 2021
6TWY
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BU of 6twy by Molmil
MAGI1_2 complexed with a phosphomimetic RSK1 peptide
分子名称: CALCIUM ION, CITRIC ACID, GLYCEROL, ...
著者Gogl, G, Cousido-Siah, A, Trave, G.
登録日2020-01-13
公開日2020-04-01
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Dual Specificity PDZ- and 14-3-3-Binding Motifs: A Structural and Interactomics Study.
Structure, 28, 2020
6L1U
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BU of 6l1u by Molmil
Cryo-EM structure of phosphorylated Tyr39 alpha-synuclein amyloid fibril
分子名称: Alpha-synuclein
著者Liu, C, Li, Y.M, Zhao, K, Lim, Y.J, Liu, Z.Y.
登録日2019-09-30
公開日2020-08-12
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (3.37 Å)
主引用文献Parkinson's disease-related phosphorylation at Tyr39 rearranges alpha-synuclein amyloid fibril structure revealed by cryo-EM.
Proc.Natl.Acad.Sci.USA, 117, 2020
6TWU
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BU of 6twu by Molmil
MAGI1_2 complexed with a phosphomimetic 16E6 peptide
分子名称: CALCIUM ION, CITRIC ACID, GLYCEROL, ...
著者Gogl, G, Cousido-Siah, A, Trave, G.
登録日2020-01-13
公開日2020-04-01
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Dual Specificity PDZ- and 14-3-3-Binding Motifs: A Structural and Interactomics Study.
Structure, 28, 2020
6EWW
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BU of 6eww by Molmil
Structure of 14-3-3 zeta in complex with CaMKK2 14-3-3 binding motif
分子名称: 14-3-3 protein zeta/delta, ARG-LYS-LEU-SEP-LEU-GLN-GLU-ARG
著者Lentini Santo, D, Obsilova, V, Obsil, T.
登録日2017-11-06
公開日2017-11-15
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.679 Å)
主引用文献14-3-3 protein directly interacts with the kinase domain of calcium/calmodulin-dependent protein kinase kinase (CaMKK2).
Biochim. Biophys. Acta, 1862, 2018
6F08
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BU of 6f08 by Molmil
14-3-3 zeta in complex with the human Son of sevenless homolog 1 (SOS1)
分子名称: 14-3-3 protein zeta/delta, PENTAETHYLENE GLYCOL, Son of sevenless homolog 1
著者Ballone, A, Centorrino, F, Ottmann, C, Guo, S, Leysen, S.
登録日2017-11-17
公開日2018-02-14
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural characterization of 14-3-3 zeta in complex with the human Son of sevenless homolog 1 (SOS1).
J. Struct. Biol., 202, 2018
6TWQ
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BU of 6twq by Molmil
MAGI1_2 complexed with a 16E6 peptide
分子名称: CALCIUM ION, CITRIC ACID, GLYCEROL, ...
著者Gogl, G, Cousido-Siah, A, Trave, G.
登録日2020-01-13
公開日2020-04-01
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Dual Specificity PDZ- and 14-3-3-Binding Motifs: A Structural and Interactomics Study.
Structure, 28, 2020
8USC
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BU of 8usc by Molmil
Nub1/Fat10-processing human 26S proteasome
分子名称: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, ...
著者Arkinson, C, Gee, C.L, Martin, A.
登録日2023-10-27
公開日2024-11-06
最終更新日2025-04-23
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献NUB1 traps unfolded FAT10 for ubiquitin-independent degradation by the 26S proteasome.
Nat.Struct.Mol.Biol., 2025
8SZK
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BU of 8szk by Molmil
The cryo-EM structure of PPP2R5A/HIV-1 Vif/CBFb/EloB/EloC complex
分子名称: Core-binding factor subunit beta, Elongin-B, Elongin-C, ...
著者Hu, Y, Xiong, Y.
登録日2023-05-30
公開日2024-06-05
最終更新日2025-05-28
実験手法ELECTRON MICROSCOPY (3.58 Å)
主引用文献Structural insights into PPP2R5A degradation by HIV-1 Vif.
Nat.Struct.Mol.Biol., 31, 2024
7QO1
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BU of 7qo1 by Molmil
complex of DNA ligase I and FEN1 on PCNA and DNA
分子名称: ADENOSINE MONOPHOSPHATE, DNA ligase 1, Flap endonuclease 1, ...
著者Blair, K, Tehseen, M, Raducanu, V.S, Shahid, T, Lancey, C, Cruehet, R, Hamdan, S, De Biasio, A.
登録日2021-12-23
公開日2023-01-11
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Mechanism of human Lig1 regulation by PCNA in Okazaki fragment sealing.
Nat Commun, 13, 2022
9E8G
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BU of 9e8g by Molmil
Nub1/Fat10-processing human 26S proteasome bound to Txnl1 with Rpt5 at top of spiral staircase
分子名称: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, ...
著者Arkinson, C, Gee, C.L, Martin, A.
登録日2024-11-05
公開日2024-12-04
実験手法ELECTRON MICROSCOPY (3.01 Å)
主引用文献Structural landscape of AAA+ ATPase motor states in the substrate-degrading human 26S proteasome reveals conformation-specific binding of TXNL1.
Biorxiv, 2024
9E8L
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BU of 9e8l by Molmil
Nub1/Fat10-processing human 26S proteasome bound to Txnl1 with Rpt4 at top of spiral staircase
分子名称: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, ...
著者Arkinson, C, Gee, C.L, Martin, A.
登録日2024-11-05
公開日2024-12-04
実験手法ELECTRON MICROSCOPY (3.59 Å)
主引用文献Structural landscape of AAA+ ATPase motor states in the substrate-degrading human 26S proteasome reveals conformation-specific binding of TXNL1.
Biorxiv, 2024
8EQV
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BU of 8eqv by Molmil
Cryo-EM structure of PRC2 in complex with the long isoform of AEBP2
分子名称: Histone-binding protein RBBP4, Histone-lysine N-methyltransferase EZH2, Polycomb protein EED, ...
著者Boudes, M, Zhang, Q, Flanigan, S.F, Davidovich, C.
登録日2022-10-09
公開日2024-07-31
最終更新日2025-06-04
実験手法ELECTRON MICROSCOPY (3.64 Å)
主引用文献To be updated
To Be Published
6TWX
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BU of 6twx by Molmil
MAGI1_2 complexed with a phosphorylated 16E6 peptide
分子名称: 16E6 peptide, CALCIUM ION, CITRIC ACID, ...
著者Gogl, G, Cousido-Siah, A, Trave, G.
登録日2020-01-13
公開日2020-04-01
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Dual Specificity PDZ- and 14-3-3-Binding Motifs: A Structural and Interactomics Study.
Structure, 28, 2020
9FQR
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BU of 9fqr by Molmil
96-nm repeat of axonemal doublet microtubules from bovine sperm
分子名称: A-kinase anchoring protein 14, ATP6V1F neighbor, Actin, ...
著者Leung, M.R, Sun, C, Zeng, J, Anderson, J.R, Niu, Q, Huang, W, Noteborn, W.E.M, Brown, A, Zeev-Ben-Mordehai, T, Zhang, R.
登録日2024-06-21
公開日2025-03-26
実験手法ELECTRON MICROSCOPY (5 Å)
主引用文献Structural diversity of axonemes across mammalian motile cilia.
Nature, 637, 2025
8VWT
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BU of 8vwt by Molmil
OGG1 bound to a nucleosome containing 8oxoG at SHL-6 (composite map)
分子名称: 601 I strand (non-damaged strand), 601 J strand (damaged strand), Histone H2A type 1, ...
著者Weaver, T.M, Ling, J.A, Freudenthal, B.D.
登録日2024-02-02
公開日2024-10-30
最終更新日2025-01-15
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Contributing factors to the oxidation-induced mutational landscape in human cells.
Nat Commun, 15, 2024
8VWV
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BU of 8vwv by Molmil
OGG1 bound to a nucleosome containing 8oxoG at SHL4 (composite map)
分子名称: 601 I strand (damaged strand), 601 J strand (non-damaged), Histone H2A type 1, ...
著者Weaver, T.M, Ling, J.A, Freudenthal, B.D.
登録日2024-02-02
公開日2024-10-30
最終更新日2025-01-15
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Contributing factors to the oxidation-induced mutational landscape in human cells.
Nat Commun, 15, 2024
8VPQ
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BU of 8vpq by Molmil
The structure of LSD1-CoREST-HDAC1 in complex with KBTBD4IPR310delinsTTYML
分子名称: Histone deacetylase 1, INOSITOL HEXAKISPHOSPHATE, Isoform 2 of Kelch repeat and BTB domain-containing protein 4, ...
著者Xie, X, Liau, B, Zheng, N.
登録日2024-01-16
公開日2024-11-27
最終更新日2025-06-11
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Converging mechanism of UM171 and KBTBD4 neomorphic cancer mutations.
Nature, 639, 2025

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件を2025-07-09に公開中

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