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1YZI
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A novel quaternary structure of human carbonmonoxy hemoglobin
分子名称: CARBON MONOXIDE, Hemoglobin alpha chain, Hemoglobin beta chain, ...
著者Safo, M.K, Abraham, D.J.
登録日2005-02-28
公開日2005-03-15
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献The enigma of the liganded hemoglobin end state: a novel quaternary structure of human carbonmonoxy hemoglobin.
Biochemistry, 44, 2005
2K0M
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BU of 2k0m by Molmil
Solution NMR structure of the uncharacterized protein from Rhodospirillum rubrum gene locus Rru_A0810. Northeast Structural Genomics Target RrR43
分子名称: Uncharacterized protein
著者Rossi, P, Wang, H, Jiang, M, Foote, E.L, Xiao, R, Liu, J, Swapna, G, Acton, T.B, Baran, M.C, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2008-02-04
公開日2008-02-19
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution NMR structure of the uncharacterized protein from Rhodospirillum rubrum gene locus Rru_A0810. Northeast Structural Genomics Target RrR43.
To be Published
2JS7
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BU of 2js7 by Molmil
Solution NMR structure of human myeloid differentiation primary response (MyD88). Northeast Structural Genomics target HR2869A
分子名称: Myeloid differentiation primary response protein MyD88
著者Rossi, P, Ramelot, T.A, Tao, X, Ciano, M, Ho, C, Ma, L.-C, Xiao, R, Acton, T.B, Kennedy, M.A, Tong, L, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2007-06-29
公開日2007-10-23
最終更新日2020-02-19
実験手法SOLUTION NMR
主引用文献Solution NMR Structure of Human Myeloid Differentiation Primary Response (MyD88).
To be Published
2JQH
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VPS4B MIT
分子名称: Vacuolar protein sorting-associating protein 4B
著者Stuchell-Brereton, M.D, Skalicky, J.J, Kieffer, C, Ghaffarian, S, Sundquist, W.I.
登録日2007-06-01
公開日2007-10-16
最終更新日2023-12-20
実験手法SOLUTION NMR
主引用文献ESCRT-III recognition by VPS4 ATPases.
Nature, 449, 2007
2JQK
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VPS4B MIT-CHMP2B Complex
分子名称: Charged multivesicular body protein 2b, Vacuolar protein sorting-associating protein 4B
著者Stuchell-Brereton, M.D, Skalicky, J.J, Kieffer, C, Ghaffarian, S, Sundquist, W.I.
登録日2007-06-02
公開日2007-10-16
最終更新日2023-12-20
実験手法SOLUTION NMR
主引用文献ESCRT-III recognition by VPS4 ATPases.
Nature, 449, 2007
2JXP
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BU of 2jxp by Molmil
Solution NMR structure of uncharacterized lipoprotein B from Nitrosomonas europaea. Northeast Structural Genomics target NeR45A
分子名称: Putative lipoprotein B
著者Rossi, P, Wang, D, Janjua, H, Owens, L, Xiao, R, Baran, M.C, Swapna, G, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2007-11-27
公開日2007-12-11
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution NMR structure of uncharacterized lipoprotein B from Nitrosomonas europaea.
To be Published
1XA9
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BU of 1xa9 by Molmil
Crystal structure of yellow fluorescent protein zFP538 K66M green mutant
分子名称: BETA-MERCAPTOETHANOL, fluorescent protein FP538
著者Remington, S.J, Wachter, R.M, Yarbrough, D.K, Branchaud, B, Anderson, D.C, Kallio, K, Lukyanov, K.A.
登録日2004-08-25
公開日2005-02-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献zFP538, a yellow-fluorescent protein from Zoanthus, contains a novel three-ring chromophore.
Biochemistry, 44, 2005
2B3W
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BU of 2b3w by Molmil
NMR structure of the E.coli protein YbiA, Northeast Structural Genomics target ET24.
分子名称: Hypothetical protein ybiA
著者Ramelot, T.A, Cort, J.R, Xiao, R, Shih, L.Y, Acton, T.B, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG)
登録日2005-09-21
公開日2005-11-01
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献NMR structure of the E.coli protein YbiA, Northeast Structural Genomics target ET24.
To be Published
2B6O
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BU of 2b6o by Molmil
Electron crystallographic structure of lens Aquaporin-0 (AQP0) (lens MIP) at 1.9A resolution, in a closed pore state
分子名称: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Lens fiber major intrinsic protein
著者Gonen, T, Cheng, Y, Sliz, P, Hiroaki, Y, Fujiyoshi, Y, Harrison, S.C, Walz, T.
登録日2005-10-03
公開日2005-12-06
最終更新日2023-08-23
実験手法ELECTRON CRYSTALLOGRAPHY (1.9 Å)
主引用文献Lipid-protein interactions in double-layered two-dimensional AQP0 crystals.
Nature, 438, 2005
1Z29
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Crystal Structures of SULT1A2 and SULT1A1*3: Implications in the bioactivation of N-hydroxy-2-acetylamino fluorine (OH-AAF)
分子名称: ACETIC ACID, ADENOSINE-3'-5'-DIPHOSPHATE, CALCIUM ION, ...
著者Lu, J, Li, H, Liu, M.C, Zhang, J, Li, M, An, X, Chang, W.
登録日2005-03-07
公開日2006-05-30
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structures of SULT1A2 and SULT1A1 *3: insights into the substrate inhibition and the role of Tyr149 in SULT1A2.
Biochem.Biophys.Res.Commun., 396, 2010
4HEE
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BU of 4hee by Molmil
Crystal structure of PPARgamma in complex with compound 13
分子名称: 5-benzyl-2-ethyl-3-{(1S)-5-[2-(1H-tetrazol-5-yl)phenyl]-2,3-dihydro-1H-inden-1-yl}-3,5-dihydro-4H-imidazo[4,5-c]pyridin-4-one, Nuclear receptor coactivator 1, Peroxisome proliferator-activated receptor gamma
著者Han, S.
登録日2012-10-03
公開日2013-08-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Design, synthesis, and evaluation of imidazo[4,5-c]pyridin-4-one derivatives with dual activity at angiotensin II type 1 receptor and peroxisome proliferator-activated receptor-gamma
Bioorg.Med.Chem.Lett., 23, 2013
4K9F
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BU of 4k9f by Molmil
Neutron structure of Perdeuterated Rubredoxin refined against 1.75 resolution data collected on the new IMAGINE instrument at HFIR, ORNL
分子名称: FE (III) ION, Rubredoxin
著者Munshi, P, Meilleur, F, Myles, D.
登録日2013-04-19
公開日2013-12-04
最終更新日2023-09-20
実験手法NEUTRON DIFFRACTION (1.75 Å)
主引用文献The IMAGINE instrument: first neutron protein structure and new capabilities for neutron macromolecular crystallography.
Acta Crystallogr.,Sect.D, 69, 2013
7NXD
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BU of 7nxd by Molmil
Cryo-EM structure of human integrin alpha5beta1 in the half-bent conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Schumacher, S, Dedden, D, Vazquez Nunez, R, Matoba, K, Takagi, J, Biertumpfel, C, Mizuno, N.
登録日2021-03-18
公開日2021-08-25
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Structural insights into integrin alpha 5 beta 1 opening by fibronectin ligand.
Sci Adv, 7, 2021
4DLJ
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BU of 4dlj by Molmil
Human p38 MAP kinase in complex with RL163
分子名称: 2-phenyl-N~4~-(2-phenylethyl)quinazoline-4,7-diamine, Mitogen-activated protein kinase 14
著者Gruetter, C, Termathe, M.
登録日2012-02-06
公開日2013-01-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Fluorophore labeled kinase detects ligands that bind within the MAPK insert of p38alpha kinase.
Plos One, 7, 2012
7OD1
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Crystal structure of RBR ubiquitin ligase ARIH2
分子名称: E3 ubiquitin-protein ligase ARIH2, ZINC ION
著者Kostrhon, S.P, Prabu, J.R, Schulman, B.A.
登録日2021-04-28
公開日2021-09-15
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献CUL5-ARIH2 E3-E3 ubiquitin ligase structure reveals cullin-specific NEDD8 activation.
Nat.Chem.Biol., 17, 2021
2D57
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Double layered 2D crystal structure of AQUAPORIN-4 (AQP4M23) at 3.2 a resolution by electron crystallography
分子名称: Aquaporin-4
著者Hiroaki, Y, Tani, K, Kamegawa, A, Gyobu, N, Nishikawa, K, Suzuki, H, Walz, T, Sasaki, S, Mitsuoka, K, Kimura, K, Mizoguchi, A, Fujiyoshi, Y.
登録日2005-10-29
公開日2006-01-31
最終更新日2023-11-08
実験手法ELECTRON CRYSTALLOGRAPHY (3.2 Å)
主引用文献Implications of the Aquaporin-4 Structure on Array Formation and Cell Adhesion
J.Mol.Biol., 355, 2005
4E6A
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p38a-PIA23 complex
分子名称: (2S)-2-methoxy-3-(octadecyloxy)propyl (1R,2R,3R,4S,6S)-2,3,4-trihydroxy-6-(2-methylpropoxy)cyclohexyl hydrogen (S)-phosphate, Mitogen-activated protein kinase 14
著者Livnah, O, Tzarum, N, Eisenberg-Domovich, Y.
登録日2012-03-15
公開日2012-10-31
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Lipid Molecules Induce p38 alpha Activation via a Novel Molecular Switch.
J.Mol.Biol., 424, 2012
4E5B
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Structure of p38a MAP kinase without BOG
分子名称: Mitogen-activated protein kinase 14
著者Livnah, O, Eisenberg-Domovich, Y, Tzarum, N.
登録日2012-03-14
公開日2012-10-31
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Lipid Molecules Induce p38 alpha Activation via a Novel Molecular Switch.
J.Mol.Biol., 424, 2012
4EH3
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Human p38 MAP kinase in complex with NP-F2 and RL87
分子名称: Mitogen-activated protein kinase 14, NARINGENIN, N~4~-cyclopropyl-2-phenylquinazoline-4,7-diamine
著者Over, B, Gruetter, C, Waldmann, H, Rauh, D.
登録日2012-04-02
公開日2012-12-05
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Natural-product-derived fragments for fragment-based ligand discovery.
Nat Chem, 5, 2012
4EH6
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Human p38 MAP kinase in complex with NP-F5 and RL87
分子名称: Mitogen-activated protein kinase 14, N-phenylpyridine-3-carboxamide, N~4~-cyclopropyl-2-phenylquinazoline-4,7-diamine
著者Over, B, Gruetter, C, Waldmann, H, Rauh, D.
登録日2012-04-02
公開日2012-12-05
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Natural-product-derived fragments for fragment-based ligand discovery.
Nat Chem, 5, 2012
7ONI
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Structure of Neddylated CUL5 C-terminal region-RBX2-ARIH2*
分子名称: Cullin-5, E3 ubiquitin-protein ligase ARIH2, NEDD8, ...
著者Kostrhon, S.P, prabu, J.R, Schulman, B.A.
登録日2021-05-25
公開日2021-09-15
最終更新日2021-10-06
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献CUL5-ARIH2 E3-E3 ubiquitin ligase structure reveals cullin-specific NEDD8 activation.
Nat.Chem.Biol., 17, 2021
4EH7
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Human p38 MAP kinase in complex with NP-F6 and RL87
分子名称: (3-phenoxyphenyl)methanol, Mitogen-activated protein kinase 14, N~4~-cyclopropyl-2-phenylquinazoline-4,7-diamine
著者Over, B, Gruetter, C, Waldmann, H, Rauh, D.
登録日2012-04-02
公開日2012-12-05
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Natural-product-derived fragments for fragment-based ligand discovery.
Nat Chem, 5, 2012
7P4Y
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GlnK2 from Methanothermococcus thermolithotrophicus in the apo state at a resolution of 2.3 A
分子名称: CHLORIDE ION, GlnK2 from Methanothermococcus thermolithotrophicus
著者Mueller, M.-C, Wagner, T.
登録日2021-07-13
公開日2021-10-06
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Oxoglutarate Binding Site and Regulatory Mechanism Are Conserved in Ammonium Transporter Inhibitors GlnKs from Methanococcales .
Int J Mol Sci, 22, 2021
7P4V
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GlnK1 from Methanothermococcus thermolithotrophicus with dADP at a resolution of 1.94 A
分子名称: 2'-DEOXYADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, GlnK1 from Methanothermococcus thermolithotrophicus
著者Mueller, M.-C, Wagner, T.
登録日2021-07-13
公開日2021-10-06
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献The Oxoglutarate Binding Site and Regulatory Mechanism Are Conserved in Ammonium Transporter Inhibitors GlnKs from Methanococcales .
Int J Mol Sci, 22, 2021
7P50
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GlnK2 from Methanothermococcus thermolithotrophicus in complex with Mg-ATP and 2-oxoglutarate at a resolution of 1.16 A
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-OXOGLUTARIC ACID, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Mueller, M.-C, Wagner, T.
登録日2021-07-13
公開日2021-10-06
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.16 Å)
主引用文献The Oxoglutarate Binding Site and Regulatory Mechanism Are Conserved in Ammonium Transporter Inhibitors GlnKs from Methanococcales .
Int J Mol Sci, 22, 2021

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