Crystal structure of the HIV-2 neutralizing Fab fragment 7C8

Summary for 3NZ8

DescriptorMouse anti V3 antibody 7C8 Fab, heavy chain, Mouse anti V3 antibody 7C8 Fab, light chain, GLYCEROL, ... (4 entities in total)
Functional Keywordsantigen binding, antibody, fab, immunological, hiv-2, v3, gp125, immune system
Biological sourceMus musculus (mouse)
Total number of polymer chains4
Total molecular weight95858.79
Uchtenhagen, H.,Friemann, R.,Raszewski, G.,Spetz, A.-L.,Nilsson, L.,Achour, A. (deposition date: 2010-07-16, release date: 2011-05-18, Last modification date: 2018-01-24)
Primary citation
Uchtenhagen, H.,Friemann, R.,Raszewski, G.,Spetz, A.L.,Nilsson, L.,Achour, A.
Crystal Structure of the HIV-2 Neutralizing Fab Fragment 7C8 with High Specificity to the V3 Region of gp125.
Plos One, 6:e18767-e18767, 2011
PubMed: 21541316 (PDB entries with the same primary citation)
DOI: 10.1371/journal.pone.0018767
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2885 0.2% 4.6% 1.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-09-23