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6ORN
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BU of 6orn by Molmil
Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch bNAb 10-1074
分子名称: 10-1074 antibody Fab heavy chain, 10-1074 antibody Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Abernathy, M.E, Gristick, H.B, Bjorkman, P.J.
登録日2019-04-30
公開日2019-06-12
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.05 Å)
主引用文献Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques.
Nature, 570, 2019
4KZE
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BU of 4kze by Molmil
Crystal structure of an RNA aptamer in complex with Fab
分子名称: BL3-6 Fab antibody, heavy chain, light chain, ...
著者Huang, H, Suslov, N.B, Li, N, Koldobskaya, Y, Rice, P.A, Piccirilli, J.A.
登録日2013-05-29
公開日2014-06-18
最終更新日2014-07-30
実験手法X-RAY DIFFRACTION (2.404 Å)
主引用文献A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore.
Nat.Chem.Biol., 10, 2014
1IGI
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BU of 1igi by Molmil
26-10 FAB:DIGOXIN COMPLEX-AFFINITY AND SPECIFICITY DUE TO SURFACE COMPLEMENTARITY
分子名称: IGG2A-KAPPA 26-10 FAB (HEAVY CHAIN), IGG2A-KAPPA 26-10 FAB (LIGHT CHAIN)
著者Jeffrey, P.D, Sheriff, S.
登録日1993-02-19
公開日1993-04-15
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献26-10 Fab-digoxin complex: affinity and specificity due to surface complementarity.
Proc.Natl.Acad.Sci.USA, 90, 1993
1IGJ
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BU of 1igj by Molmil
26-10 FAB:DIGOXIN COMPLEX-AFFINITY AND SPECIFICITY DUE TO SURFACE COMPLEMENTARITY
分子名称: DIGOXIN, IGG2A-KAPPA 26-10 FAB (HEAVY CHAIN), IGG2A-KAPPA 26-10 FAB (LIGHT CHAIN)
著者Jeffrey, P.D, Sheriff, S.
登録日1993-02-19
公開日1993-04-15
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献26-10 Fab-digoxin complex: affinity and specificity due to surface complementarity.
Proc.Natl.Acad.Sci.USA, 90, 1993
7STF
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BU of 7stf by Molmil
Structure of KRAS G12V/HLA-A*03:01 in complex with antibody fragment V2
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A alpha chain, ...
著者Wright, K.M, Gabelli, S.B, Miller, M.
登録日2021-11-12
公開日2023-05-31
最終更新日2023-10-25
実験手法ELECTRON MICROSCOPY (3.14 Å)
主引用文献Hydrophobic interactions dominate the recognition of a KRAS G12V neoantigen.
Nat Commun, 14, 2023
6ZEC
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BU of 6zec by Molmil
Crystal Structure of the Fab Fragment of a Glycosylated Lymphoma Antibody
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab fragment heavy chain, Fab fragment light chain, ...
著者Allen, J.D, Watanabe, Y, Crispin, M, Bowden, T.A.
登録日2020-06-16
公開日2021-06-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Insertion of atypical glycans into the tumor antigen-binding site identifies DLBCLs with distinct origin and behavior.
Blood, 138, 2021
7BXV
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BU of 7bxv by Molmil
11A1 antibody-peptide complex
分子名称: 1,2-ETHANEDIOL, Fab of the 11A1 antibody H chain, Fab of the 11A1 antibody L chain, ...
著者Irie, K, Irie, Y, Kita, A, Miki, K.
登録日2020-04-21
公開日2021-04-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献APOE epsilon 4 allele advances the age-dependent decline of amyloid beta clearance in the human cortex.
Biorxiv, 2022
8WO0
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BU of 8wo0 by Molmil
CryoEM structure of ZIKV rsNS1 filament
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Non-structural protein 1
著者Chew, B.L.A, Luo, D.
登録日2023-10-06
公開日2024-05-08
実験手法ELECTRON MICROSCOPY (8 Å)
主引用文献Structural basis of Zika virus NS1 multimerization and human antibody recognition
Npj Viruses, 2, 2024
8WNP
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BU of 8wnp by Molmil
ZIKV rsNS1 in complex with Fab AA12 and anti-fab nanobody
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-fab nanobody, Non-structural protein 1, ...
著者Chew, B.L.A, Luo, D.
登録日2023-10-06
公開日2024-05-08
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis of Zika virus NS1 multimerization and human antibody recognition
Npj Viruses, 2, 2024
8WO4
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BU of 8wo4 by Molmil
ZIKV rsNS1 in complex with Fab EB9 and anti-fab nanobody
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-fab nanobody, Non-structural protein 1, ...
著者Chew, B.L.A, Luo, D.
登録日2023-10-06
公開日2024-05-08
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis of Zika virus NS1 multimerization and human antibody recognition
Npj Viruses, 2, 2024
8WNU
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BU of 8wnu by Molmil
ZIKV rsNS1 in complex with Fab GB5 and anti-fab nanobody
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-fab nanobody, Non-structural protein 1, ...
著者Chew, B.L.A, Luo, D.
登録日2023-10-06
公開日2024-05-08
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural basis of Zika virus NS1 multimerization and human antibody recognition
Npj Viruses, 2, 2024
4KZD
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BU of 4kzd by Molmil
Crystal structure of an RNA aptamer in complex with fluorophore and Fab
分子名称: 4-(3,5-difluoro-4-hydroxybenzyl)-1,2-dimethyl-1H-imidazol-5-ol, BL3-6 Fab antibody, heavy chain, ...
著者Huang, H, Suslov, N.B, Li, N, Koldobskaya, Y, Rice, P.A, Piccirilli, J.A.
登録日2013-05-29
公開日2014-06-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.186 Å)
主引用文献A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore.
Nat.Chem.Biol., 10, 2014
6FFJ
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BU of 6ffj by Molmil
Anti-tumor antibody 14F7-derived single chain fragment variable (scFv)
分子名称: 14F7-derived scFv
著者Bjerregaard-Andersen, K, Heggelund, J.E, Krengel, U.
登録日2018-01-08
公開日2018-08-15
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of an L chain optimised 14F7 anti-ganglioside Fv suggests a unique tumour-specificity through an unusual H-chain CDR3 architecture.
Sci Rep, 8, 2018
4H0H
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BU of 4h0h by Molmil
Crystal structure of mimicry-recognizing 2D10 scFv with peptide
分子名称: 2D10 scFv, peptide
著者Tapryal, S, Gaur, V, Kaur, K.J, Salunke, D.M.
登録日2012-09-08
公開日2013-06-19
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural evaluation of a mimicry-recognizing paratope: plasticity in antigen-antibody interactions manifests in molecular mimicry.
J.Immunol., 191, 2013
4H0G
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BU of 4h0g by Molmil
Crystal structure of mimicry-recognizing native 2D10 scFv
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2D10 scFv
著者Tapryal, S, Gaur, V, Kaur, K.J, Salunke, D.M.
登録日2012-09-08
公開日2013-06-19
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural evaluation of a mimicry-recognizing paratope: plasticity in antigen-antibody interactions manifests in molecular mimicry.
J.Immunol., 191, 2013
1DBA
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BU of 1dba by Molmil
THREE-DIMENSIONAL STRUCTURE OF AN ANTI-STEROID FAB' AND PROGESTERONE-FAB' COMPLEX
分子名称: ETHANOL, IGG1-KAPPA DB3 FAB (HEAVY CHAIN), IGG1-KAPPA DB3 FAB (LIGHT CHAIN)
著者Arevalo, J.H, Wilson, I.A.
登録日1992-11-10
公開日1993-10-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Three-dimensional structure of an anti-steroid Fab' and progesterone-Fab' complex.
J.Mol.Biol., 231, 1993
1DBB
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BU of 1dbb by Molmil
THREE-DIMENSIONAL STRUCTURE OF AN ANTI-STEROID FAB' AND PROGESTERONE-FAB' COMPLEX
分子名称: IGG1-KAPPA DB3 FAB (HEAVY CHAIN), IGG1-KAPPA DB3 FAB (LIGHT CHAIN), PROGESTERONE
著者Arevalo, J.H, Wilson, I.A.
登録日1992-11-11
公開日1993-10-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Three-dimensional structure of an anti-steroid Fab' and progesterone-Fab' complex.
J.Mol.Biol., 231, 1993
8ELO
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BU of 8elo by Molmil
Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with antibody CC12.1 Fab and nanobody Nb-C4-225
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CC12.1 Fab heavy chain, CC12.1 Fab light chain, ...
著者Liu, H, Wilson, I.A.
登録日2022-09-26
公開日2023-07-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Fully synthetic platform to rapidly generate tetravalent bispecific nanobody-based immunoglobulins.
Proc.Natl.Acad.Sci.USA, 120, 2023
8ELQ
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BU of 8elq by Molmil
Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with antibody CC12.1 Fab and nanobody Nb-C4-255
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CC12.1 Fab heavy chain, CC12.1 Fab light chain, ...
著者Liu, H, Wilson, I.A.
登録日2022-09-26
公開日2023-07-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Fully synthetic platform to rapidly generate tetravalent bispecific nanobody-based immunoglobulins.
Proc.Natl.Acad.Sci.USA, 120, 2023
8ELP
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BU of 8elp by Molmil
Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with antibody CC12.1 Fab and nanobody Nb-C4-240
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CC12.1 Fab heavy chain, CC12.1 Fab light chain, ...
著者Liu, H, Wilson, I.A.
登録日2022-09-26
公開日2023-07-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.83 Å)
主引用文献Fully synthetic platform to rapidly generate tetravalent bispecific nanobody-based immunoglobulins.
Proc.Natl.Acad.Sci.USA, 120, 2023
1S78
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BU of 1s78 by Molmil
Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Pertuzumab Fab heavy chain, ...
著者Franklin, M.C, Carey, K.D, Vajdos, F.F, Leahy, D.J, de Vos, A.M, Sliwkowski, M.X.
登録日2004-01-29
公開日2004-04-27
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex.
Cancer Cell, 5, 2004
5CJQ
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BU of 5cjq by Molmil
Crystal structure of a trimeric influenza hemagglutinin stem in complex with an broadly neutralizing antibody CR9114
分子名称: CR9114 heavy chain, CR9114 light chain, Designed influenza hemagglutinin stem #4900, ...
著者Zhu, X, Wilson, I.A.
登録日2015-07-14
公開日2015-09-09
最終更新日2015-09-30
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献A stable trimeric influenza hemagglutinin stem as a broadly protective immunogen.
Science, 349, 2015
2FJF
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BU of 2fjf by Molmil
Structure of the G6 Fab, a phage derived VEGF binding Fab
分子名称: Heavy Chain of a VEGF binding Antibody, Light Chain of a VEGF binding Antibody
著者Wiesmann, C.
登録日2006-01-02
公開日2006-02-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structure-function studies of two synthetic anti-vascular endothelial growth factor Fabs and comparison with the Avastin Fab.
J.Biol.Chem., 281, 2006
5CJS
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BU of 5cjs by Molmil
Crystal structure of a monomeric influenza hemagglutinin stem in complex with an broadly neutralizing antibody CR9114
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CR9114 heavy chain, CR9114 light chain, ...
著者Zhu, X, Wilson, I.A.
登録日2015-07-15
公開日2015-09-09
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (4.3 Å)
主引用文献A stable trimeric influenza hemagglutinin stem as a broadly protective immunogen.
Science, 349, 2015
7A0X
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BU of 7a0x by Molmil
Structure of dimeric sodium proton antiporter NhaA, at pH 6.0, crystallized with chimeric Fab antibodies
分子名称: 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, ...
著者Fippel, A, Lentes, C.J, Mir, S.H, Wirth, C, Hunte, C.
登録日2020-08-11
公開日2022-02-23
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Molecular determinants for substrate uptake in electrogenic sodium/proton antiporters
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