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2KES
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Solution Structure of the Coiled-coil Domain of Synphilin-1
分子名称: Synphilin-1
著者Xie, Y.Y, Zhou, C.J, Zhou, Z.R, Hu, H.Y.
登録日2009-02-02
公開日2009-02-24
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Interaction with synphilin-1 promotes inclusion formation of alpha-synuclein: mechanistic insights and pathological implication.
Faseb J., 24, 2010
2KCF
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BU of 2kcf by Molmil
The NMR solution structure of the isolated Apo Pin1 WW domain
分子名称: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
著者Kowalski, J.A, Liu, K, Kelly, J.W.
登録日2008-12-19
公開日2009-01-13
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献NMR solution structure of the isolated Apo Pin1 WW domain: comparison to the x-ray crystal structures of Pin1
Biopolymers, 63, 2002
2KBU
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BU of 2kbu by Molmil
NMR solution structure of Pin1 WW domain mutant with beta turn mimic at position 12
分子名称: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
著者Fuller, A.A, Bhabha, G, Case, D.A.
登録日2008-12-08
公開日2009-07-07
最終更新日2024-07-10
実験手法SOLUTION NMR
主引用文献Evaluating beta-turn mimics as beta-sheet folding nucleators.
Proc.Natl.Acad.Sci.USA, 106, 2009
3AW6
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Crystal structure of tetragonal hen egg white lysozyme at 84.2% relative humidity
分子名称: ACETATE ION, CHLORIDE ION, Lysozyme C, ...
著者Takayama, Y, Nakasako, M.
登録日2011-03-11
公開日2011-03-30
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A few low-frequency normal modes predominantly contribute to conformational responses of hen egg white lysozyme in the tetragonal crystal to variations of molecular packing controlled by environmental humidity
Biophys.Chem., 159, 2011
3AW7
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BU of 3aw7 by Molmil
Crystal structure of tetragonal hen egg white lysozyme at 71.9% relative humidity
分子名称: ACETATE ION, CHLORIDE ION, Lysozyme C, ...
著者Takayama, Y, Nakasako, M.
登録日2011-03-11
公開日2011-03-30
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A few low-frequency normal modes predominantly contribute to conformational responses of hen egg white lysozyme in the tetragonal crystal to variations of molecular packing controlled by environmental humidity
Biophys.Chem., 159, 2011
3OJ8
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BU of 3oj8 by Molmil
Alpha-Ketoheterocycle Inhibitors of Fatty Acid Amide Hydrolase Containing Additional Conformational Contraints in the Acyl Side Chain
分子名称: (S)-[(2S)-6-phenoxy-1,2,3,4-tetrahydronaphthalen-2-yl](5-pyridin-2-yl-1,3-oxazol-2-yl)methanol, CHLORIDE ION, Fatty-acid amide hydrolase 1
著者Mileni, M, Stevens, R.C, Boger, D.L.
登録日2010-08-20
公開日2011-07-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献alpha-Ketoheterocycle Inhibitors of Fatty Acid Amide Hydrolase Containing Additional Conformational Contraints in the Acyl Side Chain
J.Med.Chem., 54, 2011
3UA1
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BU of 3ua1 by Molmil
Crystal structure of the cytochrome P4503A4-bromoergocryptine complex
分子名称: Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE, bromoergocryptine
著者Sevrioukova, I.F, Poulos, T.L.
登録日2011-10-20
公開日2011-12-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural and Mechanistic Insights into the Interaction of Cytochrome P4503A4 with Bromoergocryptine, a Type I Ligand.
J.Biol.Chem., 287, 2012
2N9E
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BU of 2n9e by Molmil
Structure of SUMO-2 bound to phosphorylated RAP80 SIM
分子名称: BRCA1-A complex subunit RAP80, Small ubiquitin-related modifier 2
著者Anamika, A, Spyracopoulos, L.
登録日2015-11-15
公開日2016-01-20
最終更新日2016-03-23
実験手法SOLUTION NMR
主引用文献Molecular Basis for Phosphorylation-dependent SUMO Recognition by the DNA Repair Protein RAP80.
J.Biol.Chem., 291, 2016
2LH0
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NMR structure of the histone-interacting N-terminal homodimeric region of Rtt106
分子名称: Histone chaperone RTT106
著者Hu, Q, Cui, G, Mer, G.
登録日2011-08-04
公開日2012-02-01
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural basis for recognition of H3K56-acetylated histone H3-H4 by the chaperone Rtt106.
Nature, 483, 2012
7SQM
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BU of 7sqm by Molmil
Discovery and Preclinical Pharmacology of INE963, A Potent and Fast-Acting Blood-Stage Antimalarial with a High Barrier to Resistance and Potential for Single-Dose Cure in Uncomplicated Malaria
分子名称: 1-[(4S)-5-(2,4-difluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]-4-methylpiperidin-4-amine, GLYCEROL, Serine/threonine-protein kinase haspin
著者Shu, W, Yokokawa, F.
登録日2021-11-05
公開日2021-12-29
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Failure of artesunate-mefloquine combination therapy for uncompli-cated Plasmodium falciparum malaria in southern Cambodia.
Malar. J., 2009, 8, 10, 2009
6M6I
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BU of 6m6i by Molmil
Structure of HSV2 B-capsid portal vertex
分子名称: Coiled coils chain 1, Coiled coils chain 2, Major capsid protein, ...
著者Wang, X.X, Wang, N.
登録日2020-03-14
公開日2021-03-10
実験手法ELECTRON MICROSCOPY (4.05 Å)
主引用文献Structures of the portal vertex reveal essential protein-protein interactions for Herpesvirus assembly and maturation.
Protein Cell, 11, 2020
6M6H
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Structure of HSV2 C-capsid portal vertex
分子名称: Capsid vertex component 1, Capsid vertex component 2, Large tegument protein deneddylase, ...
著者Wang, X.X, Wang, N.
登録日2020-03-14
公開日2021-03-24
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structures of the portal vertex reveal essential protein-protein interactions for Herpesvirus assembly and maturation.
Protein Cell, 11, 2020
6M6G
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Structure of HSV2 viron capsid portal vertex
分子名称: Capsid vertex component 1, Capsid vertex component 2, Coiled coils, ...
著者Wang, X.X, Wang, N.
登録日2020-03-14
公開日2021-03-24
実験手法ELECTRON MICROSCOPY (5.39 Å)
主引用文献Structures of the portal vertex reveal essential protein-protein interactions for Herpesvirus assembly and maturation.
Protein Cell, 11, 2020
4HC7
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BU of 4hc7 by Molmil
Crystal structure of the full DNA binding domain of GATA3-complex 2
分子名称: DNA (5'-D(*AP*AP*GP*GP*TP*TP*AP*TP*CP*TP*CP*TP*GP*AP*TP*TP*TP*AP*GP*G)-3'), DNA (5'-D(*TP*TP*CP*CP*TP*AP*AP*AP*TP*CP*AP*GP*AP*GP*AP*TP*AP*AP*CP*C)-3'), Trans-acting T-cell-specific transcription factor GATA-3, ...
著者Chen, Y, Bates, D.L, Dey, R, Chen, L.
登録日2012-09-28
公開日2012-12-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献DNA Binding by GATA Transcription Factor Suggests Mechanisms of DNA Looping and Long-Range Gene Regulation.
Cell Rep, 2, 2012
6Q1F
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BU of 6q1f by Molmil
Atomic structure of the Human Herpesvirus 6B Capsid and Capsid-Associated Tegument Complexes
分子名称: Large structural phosphoprotein, Major capsid protein, Small capsomere-interacting protein, ...
著者Zhang, Y.B, Liu, W, Li, Z.H, Kumar, V, Alvarez-Cabrera, A.L, Leibovitch, E, Cui, Y.X, Mei, Y, Bi, G.Q, Jacobson, S, Zhou, Z.H.
登録日2019-08-03
公開日2019-12-11
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (9 Å)
主引用文献Atomic structure of the human herpesvirus 6B capsid and capsid-associated tegument complexes.
Nat Commun, 10, 2019
4HC9
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DNA binding by GATA transcription factor-complex 3
分子名称: DNA (5'-D(*AP*AP*GP*GP*TP*TP*AP*TP*CP*TP*CP*TP*GP*AP*TP*TP*TP*AP*GP*G)-3'), DNA (5'-D(*TP*TP*CP*CP*TP*AP*AP*AP*TP*CP*AP*GP*AP*GP*AP*TP*AP*AP*CP*C)-3'), Trans-acting T-cell-specific transcription factor GATA-3, ...
著者Chen, Y, Bates, D.L, Dey, R, Chen, L.
登録日2012-09-28
公開日2012-12-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献DNA Binding by GATA Transcription Factor Suggests Mechanisms of DNA Looping and Long-Range Gene Regulation.
Cell Rep, 2, 2012
6NHJ
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BU of 6nhj by Molmil
Atomic structures and deletion mutant reveal different capsid-binding patterns and functional significance of tegument protein pp150 in murine and human cytomegaloviruses with implications for therapeutic development
分子名称: Major capsid protein, Minor capsid protein, Small capsomere-interacting protein, ...
著者Liu, W, Dai, X.H, Jih, J, Chan, K, Trang, P, Yu, X.K, Balogun, R, Mei, Y, Liu, F.Y, Zhou, Z.H.
登録日2018-12-22
公開日2019-03-06
最終更新日2019-11-27
実験手法ELECTRON MICROSCOPY (5 Å)
主引用文献Atomic structures and deletion mutant reveal different capsid-binding patterns and functional significance of tegument protein pp150 in murine and human cytomegaloviruses with implications for therapeutic development.
PLoS Pathog., 15, 2019
1FBI
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BU of 1fbi by Molmil
CRYSTAL STRUCTURE OF A CROSS-REACTION COMPLEX BETWEEN FAB F9.13.7 AND GUINEA-FOWL LYSOZYME
分子名称: GUINEA FOWL LYSOZYME, IGG1 F9.13.7 FAB (HEAVY CHAIN), IGG1 F9.13.7 FAB (LIGHT CHAIN)
著者Lescar, J, Alzari, P.M.
登録日1995-01-19
公開日1995-02-27
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of a cross-reaction complex between Fab F9.13.7 and guinea fowl lysozyme.
J.Biol.Chem., 270, 1995
6NRX
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Crystal structure of DIP-eta IG1 homodimer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Dpr-interacting protein eta, isoform B, ...
著者Cheng, S, Park, Y.J, Kurleto, J.D, Ozkan, E.
登録日2019-01-24
公開日2019-02-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Molecular basis of synaptic specificity by immunoglobulin superfamily receptors in Drosophila.
Elife, 8, 2019
6NRQ
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Crystal structure of Dpr10 IG1 bound to DIP-alpha IG1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Defective proboscis extension response 10, isoform A, ...
著者Cheng, S, Park, Y.J, Kurleto, J.D, Ozkan, E.
登録日2019-01-24
公開日2019-02-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Molecular basis of synaptic specificity by immunoglobulin superfamily receptors in Drosophila.
Elife, 8, 2019
6NRW
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Crystal structure of Dpr1 IG1 bound to DIP-eta IG1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Cheng, S, Park, Y.J, Kurleto, J.D, Ozkan, E.
登録日2019-01-24
公開日2019-02-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular basis of synaptic specificity by immunoglobulin superfamily receptors in Drosophila.
Elife, 8, 2019
6NYH
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Structure of human RIPK1 kinase domain in complex with GNE684
分子名称: (5S)-N-[(3S)-7-methoxy-1-methyl-2-oxo-2,3,4,5-tetrahydro-1H-pyrido[3,4-b]azepin-3-yl]-5-phenyl-6,7-dihydro-5H-pyrrolo[1,2-b][1,2,4]triazole-2-carboxamide, IODIDE ION, Receptor-interacting serine/threonine-protein kinase 1
著者Fong, R, Lupardus, P.J.
登録日2019-02-11
公開日2019-05-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献RIP1 inhibition blocks inflammatory diseases but not tumor growth or metastases.
Cell Death Differ., 27, 2020
4HCA
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DNA binding by GATA transcription factor-complex 1
分子名称: DNA (5'-D(*AP*AP*TP*GP*TP*CP*CP*AP*TP*CP*TP*GP*AP*TP*AP*AP*GP*AP*CP*G)-3'), DNA (5'-D(*TP*TP*CP*GP*TP*CP*TP*TP*AP*TP*CP*AP*GP*AP*TP*GP*GP*AP*CP*A)-3'), Trans-acting T-cell-specific transcription factor GATA-3, ...
著者Chen, Y, Bates, D.L, Dey, R, Chen, L.
登録日2012-09-28
公開日2012-12-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献DNA Binding by GATA Transcription Factor Suggests Mechanisms of DNA Looping and Long-Range Gene Regulation.
Cell Rep, 2, 2012
7UKH
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Human Kv4.2-KChIP2-DPP6 channel complex in an open state, intracellular region
分子名称: CALCIUM ION, Isoform 2 of Kv channel-interacting protein 2, Potassium voltage-gated channel subfamily D member 2, ...
著者Zhao, H, Dai, Y, Lee, C.H.
登録日2022-04-01
公開日2022-06-29
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (2.33 Å)
主引用文献Activation and closed-state inactivation mechanisms of the human voltage-gated K V 4 channel complexes.
Mol.Cell, 82, 2022
6OKO
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Crystal structure of mRIPK3 complexed with N-(3-fluoro-4-{1H-pyrrolo[2,3-b]pyridin-4-yloxy}phenyl)-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide
分子名称: 1-(4-fluorophenyl)-N-[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]-2-oxo-1,2-dihydropyridine-3-carboxamide, Receptor-interacting serine/threonine-protein kinase 3
著者Pokross, M.E.
登録日2019-04-14
公開日2019-07-17
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Identification of RIPK3 Type II Inhibitors Using High-Throughput Mechanistic Studies in Hit Triage.
Acs Med.Chem.Lett., 11, 2020

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件を2024-09-04に公開中

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