5CXZ
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![BU of 5cxz by Molmil](/molmil-images/mine/5cxz) | SYK catalytic domain complexed with naphthyridine inhibitor | 分子名称: | CHLORIDE ION, GLYCEROL, N-{7-[4-(dimethylamino)phenyl]-1,6-naphthyridin-5-yl}propane-1,3-diamine, ... | 著者 | Thoma, G, Veenstra, S, Strang, R, Blanz, J, Vangrevelinghe, E, Berghausen, J, Lee, C.C, Zerwes, H.-G. | 登録日 | 2015-07-29 | 公開日 | 2015-09-16 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Orally bioavailable Syk inhibitors with activity in a rat PK/PD model. Bioorg.Med.Chem.Lett., 25, 2015
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5V5B
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![BU of 5v5b by Molmil](/molmil-images/mine/5v5b) | KVQIINKKLD, Structure of the amyloid spine from microtubule associated protein tau Repeat 2 | 分子名称: | Microtubule-associated protein tau | 著者 | Seidler, P.M, Sawaya, M.R, Rodriguez, J.A, Eisenberg, D.S, Cascio, D, Boyer, D.R. | 登録日 | 2017-03-13 | 公開日 | 2018-02-07 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.5 Å) | 主引用文献 | Structure-based inhibitors of tau aggregation. Nat Chem, 10, 2018
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5D5X
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![BU of 5d5x by Molmil](/molmil-images/mine/5d5x) | Crystal structure of Chaetomium thermophilum Skn7 with SSRE DNA | 分子名称: | Putative transcription factor, SSRE DNA strand 1, SSRE DNA strand 2 | 著者 | Neudegger, T, Verghese, J, Hayer-Hartl, M, Hartl, F.U, Bracher, A. | 登録日 | 2015-08-11 | 公開日 | 2015-12-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure of human heat-shock transcription factor 1 in complex with DNA. Nat.Struct.Mol.Biol., 23, 2016
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5D5V
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![BU of 5d5v by Molmil](/molmil-images/mine/5d5v) | Crystal structure of human Hsf1 with Satellite III repeat DNA | 分子名称: | DNA, Heat shock factor protein 1, MAGNESIUM ION | 著者 | Neudegger, T, Verghese, J, Hayer-Hartl, M, Hartl, F.U, Bracher, A. | 登録日 | 2015-08-11 | 公開日 | 2015-12-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Structure of human heat-shock transcription factor 1 in complex with DNA. Nat.Struct.Mol.Biol., 23, 2016
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4ZZV
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![BU of 4zzv by Molmil](/molmil-images/mine/4zzv) | Geotrichum candidum Cel7A apo structure at 1.4A | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CELLOBIOHYDROLASE I, ... | 著者 | Borisova, A.S, Stahlberg, J. | 登録日 | 2015-04-14 | 公開日 | 2015-09-23 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | 主引用文献 | Sequencing, Biochemical Characterization, Crystal Structure and Molecular Dynamics of Cellobiohydrolase Cel7A from Geotrichum Candidum 3C. FEBS J., 282, 2015
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5A8Z
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![BU of 5a8z by Molmil](/molmil-images/mine/5a8z) | Crystal Structure of human neutrophil elastase in complex with a dihydropyrimidone inhibitor | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[(4R)-7-methyl-2,5-bis(oxidanylidene)-1-[3-(trifluoromethyl)phenyl]-3,4,6,8-tetrahydropyrimido[4,5-d]pyridazin-4-yl]benzenecarbonitrile, Neutrophil elastase, ... | 著者 | von Nussbaum, F, Li, V.M, Meibom, D, Anlauf, S, Bechem, M, Delbeck, M, Gerisch, M, Harrenga, A, Karthaus, D, Lang, D, Lustig, K, Mittendorf, J, Schaefer, M, Schaefer, S, Schamberger, J. | 登録日 | 2015-07-17 | 公開日 | 2016-08-03 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Potent and Selective Human Neutrophil Elastase Inhibitors with Novel Equatorial Ring Topology: in vivo Efficacy of the Polar Pyrimidopyridazine BAY-8040 in a Pulmonary Arterial Hypertension Rat Model. ChemMedChem, 11, 2016
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7PWF
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![BU of 7pwf by Molmil](/molmil-images/mine/7pwf) | Cryo-EM structure of small subunit of Giardia lamblia ribosome at 2.9 A resolution | 分子名称: | 40S ribosomal protein S21, 40S ribosomal protein S25, 40S ribosomal protein S26, ... | 著者 | Hiregange, D.G, Rivalta, A, Bose, T, Breiner-Goldstein, E, Samiya, S, Cimicata, G, Kulakova, L, Zimmerman, E, Bashan, A, Herzberg, O, Yonath, A. | 登録日 | 2021-10-06 | 公開日 | 2022-05-25 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | 主引用文献 | Cryo-EM structure of the ancient eukaryotic ribosome from the human parasite Giardia lamblia. Nucleic Acids Res., 50, 2022
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5A7R
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![BU of 5a7r by Molmil](/molmil-images/mine/5a7r) | Human poly(ADP-ribose) glycohydrolase in complex with synthetic dimeric ADP-ribose | 分子名称: | BETA-MERCAPTOETHANOL, GLYCEROL, POLY(ADP-RIBOSE) GLYCOHYDROLASE, ... | 著者 | Lambrecht, M.J, Brichacek, M, Barkauskaite, E, Ariza, A, Ahel, I, Hergenrother, P.J. | 登録日 | 2015-07-09 | 公開日 | 2015-07-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Synthesis of Dimeric Adp-Ribose and its Structure with Human Poly(Adp-Ribose) Glycohydrolase. J.Am.Chem.Soc., 137, 2015
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5D5W
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![BU of 5d5w by Molmil](/molmil-images/mine/5d5w) | Crystal structure of Chaetomium thermophilum Skn7 with HSE DNA | 分子名称: | HSE DNA, Putative transcription factor | 著者 | Neudegger, T, Verghese, J, Hayer-Hartl, M, Hartl, F.U, Bracher, A. | 登録日 | 2015-08-11 | 公開日 | 2015-12-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structure of human heat-shock transcription factor 1 in complex with DNA. Nat.Struct.Mol.Biol., 23, 2016
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5D5Z
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![BU of 5d5z by Molmil](/molmil-images/mine/5d5z) | Structure of Chaetomium thermophilum Skn7 coiled-coil domain, crystal form II | 分子名称: | Putative transcription factor | 著者 | Neudegger, T, Verghese, J, Hayer-Hartl, M, Bracher, A, Hartl, F.U. | 登録日 | 2015-08-11 | 公開日 | 2015-12-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure of human heat-shock transcription factor 1 in complex with DNA. Nat.Struct.Mol.Biol., 23, 2016
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5DBN
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![BU of 5dbn by Molmil](/molmil-images/mine/5dbn) | Crystal structure of AtoDA complex | 分子名称: | Acetate CoA-transferase subunit alpha, Acetate CoA-transferase subunit beta, CHLORIDE ION, ... | 著者 | Arbing, M.A, Koo, C.W, Shin, A, Medrano-Soto, A, Eisenberg, D. | 登録日 | 2015-08-21 | 公開日 | 2016-08-24 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.549 Å) | 主引用文献 | Crystal structure of AtoDA complex To Be Published
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7R5Z
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6WPI
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![BU of 6wpi by Molmil](/molmil-images/mine/6wpi) | Crystal structure of Nop9 in complex with ITS1 RNA | 分子名称: | 3,3',3''-phosphanetriyltripropanoic acid, GLYCEROL, Nucleolar protein 9, ... | 著者 | Zhang, J, Qiu, C, Hall, T.M.T. | 登録日 | 2020-04-27 | 公開日 | 2020-05-20 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.02 Å) | 主引用文献 | Nop9 recognizes structured and single-stranded RNA elements of preribosomal RNA. Rna, 26, 2020
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5D5Y
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![BU of 5d5y by Molmil](/molmil-images/mine/5d5y) | Structure of Chaetomium thermophilum Skn7 coiled-coil domain, crystal form I | 分子名称: | Putative transcription factor | 著者 | Neudegger, T, Verghese, J, Hayer-Hartl, M, Hartl, F.U, Bracher, A. | 登録日 | 2015-08-11 | 公開日 | 2015-12-30 | 最終更新日 | 2016-02-10 | 実験手法 | X-RAY DIFFRACTION (1.03 Å) | 主引用文献 | Structure of human heat-shock transcription factor 1 in complex with DNA. Nat.Struct.Mol.Biol., 23, 2016
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5D2A
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![BU of 5d2a by Molmil](/molmil-images/mine/5d2a) | Bifunctional dendrimers | 分子名称: | 3,7-anhydro-2,8-dideoxy-L-glycero-D-gluco-octonic acid, CALCIUM ION, Fucose-binding lectin, ... | 著者 | Michaud, G, Visini, R, Stocker, A, Darbre, T, Reymond, J.L. | 登録日 | 2015-08-05 | 公開日 | 2016-02-10 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.134 Å) | 主引用文献 | Overcoming antibiotic resistance inPseudomonas aeruginosabiofilms using glycopeptide dendrimers. Chem Sci, 7, 2016
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5D5U
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![BU of 5d5u by Molmil](/molmil-images/mine/5d5u) | Crystal structure of human Hsf1 with HSE DNA | 分子名称: | Heat shock Element DNA, Heat shock factor protein 1 | 著者 | Neudegger, T, Verghese, J, Hayer-Hartl, M, Hartl, F.U, Bracher, A. | 登録日 | 2015-08-11 | 公開日 | 2015-12-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | 主引用文献 | Structure of human heat-shock transcription factor 1 in complex with DNA. Nat.Struct.Mol.Biol., 23, 2016
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5D60
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![BU of 5d60 by Molmil](/molmil-images/mine/5d60) | Structure of Chaetomium thermophilum Skn7 coiled-coil domain, crystal form III | 分子名称: | Putative transcription factor | 著者 | Neudegger, T, Verghese, J, Hayer-Hartl, M, Hartl, F.U, Bracher, A. | 登録日 | 2015-08-11 | 公開日 | 2016-06-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure of human heat-shock transcription factor 1 in complex with DNA. Nat.Struct.Mol.Biol., 23, 2016
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5DEA
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![BU of 5dea by Molmil](/molmil-images/mine/5dea) | Crystal structure of the complex between human FMRP RGG motif and G-quadruplex RNA, cesium bound form. | 分子名称: | CESIUM ION, Fragile X mental retardation protein 1, POTASSIUM ION, ... | 著者 | Vasilyev, N, Polonskaia, A, Darnell, J.C, Darnell, R.B, Patel, D.J, Serganov, A. | 登録日 | 2015-08-25 | 公開日 | 2015-09-23 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.7973 Å) | 主引用文献 | Crystal structure reveals specific recognition of a G-quadruplex RNA by a beta-turn in the RGG motif of FMRP. Proc.Natl.Acad.Sci.USA, 112, 2015
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5DAD
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![BU of 5dad by Molmil](/molmil-images/mine/5dad) | Crystal Structure of Human KEAP1 BTB Domain in Complex with Small Molecule TX64014 | 分子名称: | (6aS,7S,10aS)-8-hydroxy-4-methoxy-2,7,10a-trimethyl-5,6,6a,7,10,10a-hexahydrobenzo[h]quinazoline-9-carbonitrile, Kelch-like ECH-associated protein 1 | 著者 | Huerta, C, Jiang, X, Trevino, I, Bender, C.F, Swinger, K.K, Stoll, V.S, Ferguson, D.A, Thomas, P.J, Probst, B, Dulubova, I, Visnick, M, Wigley, W.C. | 登録日 | 2015-08-19 | 公開日 | 2016-08-10 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | Characterization of novel small-molecule NRF2 activators: Structural and biochemical validation of stereospecific KEAP1 binding. Biochim.Biophys.Acta, 1860, 2016
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5DE8
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![BU of 5de8 by Molmil](/molmil-images/mine/5de8) | Crystal structure of the complex between human FMRP RGG motif and G-quadruplex RNA, iridium hexammine bound form. | 分子名称: | Fragile X mental retardation protein 1, IRIDIUM HEXAMMINE ION, POTASSIUM ION, ... | 著者 | Vasilyev, N, Polonskaia, A, Darnell, J.C, Darnell, R.B, Patel, D.J, Serganov, A. | 登録日 | 2015-08-25 | 公開日 | 2015-09-23 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3.1003 Å) | 主引用文献 | Crystal structure reveals specific recognition of a G-quadruplex RNA by a beta-turn in the RGG motif of FMRP. Proc.Natl.Acad.Sci.USA, 112, 2015
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7R0H
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![BU of 7r0h by Molmil](/molmil-images/mine/7r0h) | STRUCTURAL BASIS OF ION UPTAKE IN COPPER-TRANSPORTING P1B-TYPE ATPASES | 分子名称: | COPPER (II) ION, Putative copper-exporting P-type ATPase A | 著者 | Salustros, N, Groenberg, C, Wang, K, Gourdon, P. | 登録日 | 2022-02-02 | 公開日 | 2022-09-14 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.31 Å) | 主引用文献 | Structural basis of ion uptake in copper-transporting P 1B -type ATPases. Nat Commun, 13, 2022
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7R0I
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![BU of 7r0i by Molmil](/molmil-images/mine/7r0i) | STRUCTURAL BASIS OF ION UPTAKE IN COPPER-TRANSPORTING P1B-TYPE ATPASES | 分子名称: | MAGNESIUM ION, POTASSIUM ION, Putative copper-exporting P-type ATPase A | 著者 | Salustros, N, Groenberg, C, Wang, K, Gourdon, P. | 登録日 | 2022-02-02 | 公開日 | 2022-09-14 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural basis of ion uptake in copper-transporting P 1B -type ATPases. Nat Commun, 13, 2022
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7R0G
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7RK5
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![BU of 7rk5 by Molmil](/molmil-images/mine/7rk5) | |
7RK4
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![BU of 7rk4 by Molmil](/molmil-images/mine/7rk4) | |