PDB: 223532 件ウェブページステータス検索Chemie searchBIRD

---

1H3J	STRUCTURE OF RECOMBINANT COPRINUS CINEREUS PEROXIDASE DETERMINED TO 2.0 A 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, MAGNESIUM ION, ... 著者 Petersen, J.F.W, Houborg, K, Harris, P, Larsen, S. 登録日 2002-09-05 公開日 2003-06-12 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Impact of the Physical and Chemical Environment on the Molecular Structure of Coprinus Cinereus Peroxidase Acta Crystallogr.,Sect.D, 59, 2003
3BU5	Crystal structure of the insulin receptor kinase in complex with IRS2 KRLB peptide and ATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Insulin receptor substrate 2, MAGNESIUM ION, ... 著者 Wu, J, Hubbard, S.R. 登録日 2007-12-31 公開日 2008-02-19 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural and biochemical characterization of the KRLB region in insulin receptor substrate-2. Nat.Struct.Mol.Biol., 15, 2008
5JF5	Crystal structure of type 2 PDF from Streptococcus agalactiae in complex with inhibitor AT020 分子名称: (3R)-3-{3-[(2H-1,3-benzodioxol-5-yl)methyl]-1,2,4-oxadiazol-5-yl}-4-cyclopentyl-N-hydroxybutanamide, ACETATE ION, IMIDAZOLE, ... 著者 Fieulaine, S, Giglione, C, Meinnel, T. 登録日 2016-04-19 公開日 2016-11-30 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A unique peptide deformylase platform to rationally design and challenge novel active compounds. Sci Rep, 6, 2016
8H66	Crystal structure of human GCN5 histone acetyltransferase domain bound with propionyl-CoA 分子名称: Histone acetyltransferase KAT2A, propionyl Coenzyme A 著者 Li, N, Tao, Y.J, Guo, Y.R. 登録日 2022-10-15 公開日 2023-05-03 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Molecular Basis of KAT2A Selecting Acyl-CoA Cofactors for Histone Modifications. Res, 6, 2023
3BL0	Carbonic anhydrase inhibitors. Interaction of 2-N,N-Dimethylamino-1,3,4-thiadiazole-5-methanesulfonamide with twelve mammalian isoforms: kinetic and X-Ray crystallographic studies 分子名称: 1-[5-(dimethylamino)-1,3,4-thiadiazol-2-yl]methanesulfonamide, Carbonic anhydrase 2, MERCURIBENZOIC ACID, ... 著者 Temperini, C, Supuran, C.T, Blackburn, G.M. 登録日 2007-12-10 公開日 2008-01-22 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Carbonic anhydrase inhibitors. Interaction of 2-N,N-dimethylamino-1,3,4-thiadiazole-5-methanesulfonamide with 12 mammalian isoforms: kinetic and X-ray crystallographic studies. Bioorg.Med.Chem.Lett., 18, 2008
1QMQ	Optical detection of cytochrome P450 by sensitizer-linked substrates 分子名称: ACETATE ION, CYTOCHROME P450, DELTA-BIS(2,2'-BIPYRIDINE)-(5-METHYL-2-2'-BIPYRIDINE)-C9-ADAMANTANE RUTHENIUM (II), ... 著者 Crane, B.R, Dmochowski, I.J, Gray, H.B. 登録日 1999-10-05 公開日 2000-10-06 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Optical Detection of Cytochrome P450 by Sensitizer-Linked Substrates Proc.Natl.Acad.Sci.USA, 96, 1999
3BVS	Crystal Structure of Bacillus cereus Alkylpurine DNA Glycosylase AlkD 分子名称: Alkylpurine DNA Glycosylase AlkD 著者 Rubinson, E.H, Eichman, B.F. 登録日 2008-01-07 公開日 2008-07-15 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 A New Protein Architecture for Processing Alkylation Damaged DNA: The Crystal Structure of DNA Glycosylase AlkD. J.Mol.Biol., 381, 2008
5JG0	Staphylococcus aureus Dihydrofolate Reductase complexed with beta-NADPH and UCP1191 分子名称: 4-{6-[(2S)-4-(2,4-diamino-6-ethylpyrimidin-5-yl)but-3-yn-2-yl]-2H-1,3-benzodioxol-4-yl}benzoic acid, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Anderson, A.C, Reeve, S.M. 登録日 2016-04-19 公開日 2017-04-19 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.879 Å) 主引用文献 MRSA Isolates from United States Hospitals Carry dfrG and dfrK Resistance Genes and Succumb to Propargyl-Linked Antifolates. Cell Chem Biol, 23, 2016
5J59	Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor (Chem 1893) 分子名称: 5-chloro-N-(2-{[(3,5-dichlorophenyl)methyl]amino}ethyl)-N-methyl-3H-imidazo[4,5-b]pyridin-2-amine, GLYCEROL, METHIONINE, ... 著者 Barros-Alvarez, X, Hol, W.G.J. 登録日 2016-04-01 公開日 2017-01-25 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure-guided design of novel Trypanosoma brucei Methionyl-tRNA synthetase inhibitors. Eur J Med Chem, 124, 2016
1QNC	Crystal structure of the A(-31) Adenovirus major late promoter TATA box variant bound to wild-type TBP (Arabidopsis thaliana TBP isoform 2). TATA element recognition by the TATA box-binding protein has been conserved throughout evolution. 分子名称: DNA (5'-D(*GP*CP*AP*AP*TP*AP*AP*AP*AP*GP*GP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*CP*CP*TP*TP*TP*TP*AP*TP*TP*GP*C)-3'), TRANSCRIPTION INITIATION FACTOR TFIID-1 著者 Patikoglou, G.A, Kim, J.L, Sun, L, Yang, S.-H, Kodadek, T, Burley, S.K. 登録日 1999-10-14 公開日 2000-02-07 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 TATA Element Recognition by the TATA Box-Binding Protein Has Been Conserved Throughout Evolution Genes Dev., 13, 1999
5J5L	CRYSTAL STRUCTURE OF AFMP4P IN COMPLEX WITH ARACHIDONIC ACID 分子名称: ARACHIDONIC ACID, Uncharacterized protein 著者 Zhang, H, Hao, Q. 登録日 2016-04-03 公開日 2017-04-05 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 A Novel Class Of Virulence Factors In Penicillium Marneffei And Aspergillus Fumigatus Enhances Intracellular Survival In Monocytes By Arachidonic Acid Binding To Be Published
5JG7	Crystal structure of putative periplasmic binding protein from Salmonella typhimurium LT2 分子名称: Fur regulated Salmonella iron transporter, GLYCEROL 著者 Chang, C, Zhou, M, Shatsman, S, Joachimiak, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2016-04-19 公開日 2016-04-27 最終更新日 2016-07-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of putative periplasmic binding protein from Salmonella typhimurium LT2 To Be Published
5B25	Crystal structure of human PDE1B with inhibitor 3 分子名称: (11R,15S)-4-{[4-(6-fluoropyridin-2-yl)phenyl]methyl}-8-methyl-5-(phenylamino)-1,3,4,8,10-pentaazatetracyclo[7.6.0.02,6.011,15]pentadeca-2,5,9-trien-7-one, Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B, GLYCEROL, ... 著者 Ida, K, Lane, W, Snell, G, Sogabe, S. 登録日 2016-01-07 公開日 2016-02-03 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Discovery of Potent and Selective Inhibitors of Phosphodiesterase 1 for the Treatment of Cognitive Impairment Associated with Neurodegenerative and Neuropsychiatric Diseases J.Med.Chem., 59, 2016
5J5Z	Crystal structure of the D444V disease-causing mutant of the human dihydrolipoamide dehydrogenase 分子名称: Dihydrolipoyl dehydrogenase, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Szabo, E, Mizsei, R, Zambo, Z, Torocsik, B, Weiss, M.S, Adam-Vizi, V, Ambrus, A. 登録日 2016-04-04 公開日 2017-11-15 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Crystal structures of the disease-causing D444V mutant and the relevant wild type human dihydrolipoamide dehydrogenase. Free Radic. Biol. Med., 124, 2018
1QPH	CRYSTAL STRUCTURE OF THE A-DNA DODECAMER GACCACGTGGTC 分子名称: 5'-D(P*GP*AP*CP*CP*AP*CP*GP*TP*GP*GP*TP*CP)-3' 著者 Raaijmakers, H, Suck, D, Mayer, C. 登録日 1999-05-25 公開日 1999-05-27 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal Structure Analysis of the A-DNA Dodecamer GACCACGTGGTC To be Published
6VUZ	Crystal structure of Eis from Mycobacterium tuberculosis in complex with inhibitor SGT353 分子名称: 2-{[3-(piperidin-1-yl)propyl]sulfanyl}-6,7-dihydro-5H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-amine, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Punetha, A, Hou, C, Ngo, H.X, Garneau-Tsodikova, S, Tsodikov, O.V. 登録日 2020-02-16 公開日 2020-06-03 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structure-Guided Optimization of Inhibitors of Acetyltransferase Eis fromMycobacterium tuberculosis. Acs Chem.Biol., 15, 2020
5JH9	Crystal structure of prApe1 分子名称: CACODYLATE ION, Vacuolar aminopeptidase 1, ZINC ION 著者 Noda, N.N, Adachi, W, Inagaki, F. 登録日 2016-04-20 公開日 2016-06-29 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural Basis for Receptor-Mediated Selective Autophagy of Aminopeptidase I Aggregates Cell Rep, 16, 2016
7AGH	Crystal structure of SF kinase YihV from E. coli in complex with AMPPNP-Mg 分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Sulfofructose kinase 著者 Sharma, M, Davies, G.J, Jin, Y. 登録日 2020-09-22 公開日 2021-04-14 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.93 Å) 主引用文献 Molecular Basis of Sulfosugar Selectivity in Sulfoglycolysis. Acs Cent.Sci., 7, 2021
5IYD	Human core-PIC in the initial transcribing state (no IIS) 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ... 著者 He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. 登録日 2016-03-24 公開日 2016-05-18 最終更新日 2019-11-20 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Near-atomic resolution visualization of human transcription promoter opening. Nature, 533, 2016
7SF3	SARS-CoV-2 Main Protease (Mpro) in Complex with ML1006m 分子名称: (1R,2S,5S)-N-{(2S,3R)-3-hydroxy-4-(methylamino)-4-oxo-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase, CHLORIDE ION 著者 Westberg, M, Fernandez, D, Lin, M.Z. 登録日 2021-10-02 公開日 2022-10-05 最終更新日 2024-04-17 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 An orally bioavailable SARS-CoV-2 main protease inhibitor exhibits improved affinity and reduced sensitivity to mutations. Sci Transl Med, 16, 2024
6W39	Structure of unphosphorylated IRE1 in complex with G-1749 分子名称: Serine/threonine-protein kinase/endoribonuclease IRE1, ethyl ~{N}-[6-methyl-5-[3-[2-[[(3~{S})-piperidin-3-yl]amino]pyrimidin-4-yl]pyridin-2-yl]oxy-naphthalen-1-yl]carbamate 著者 Ferri, E, Wang, W, Joachim, R, Mortara, K. 登録日 2020-03-09 公開日 2020-12-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.736 Å) 主引用文献 Activation of the IRE1 RNase through remodeling of the kinase front pocket by ATP-competitive ligands. Nat Commun, 11, 2020
5IZE	Hantaan virus L protein cap-snatching endonuclease 分子名称: MANGANESE (III) ION, RNA-directed RNA polymerase L 著者 Reguera, J, Cusack, S. 登録日 2016-03-25 公開日 2016-06-29 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Comparative Structural and Functional Analysis of Bunyavirus and Arenavirus Cap-Snatching Endonucleases. Plos Pathog., 12, 2016
1QRI	X-RAY STRUCTURE OF THE DNA-ECO RI ENDONUCLEASE COMPLEXES WITH AN E144D MUTATION AT 2.7 A 分子名称: 5'-D(*TP*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', ECO RI ENDONCULEASE 著者 Choi, J, Kim, Y, Greene, P, Hager, P, Rosenberg, J.M. 登録日 1999-06-14 公開日 1999-06-23 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 X-Ray Structure of the DNA-Eco RI Endonuclease Complexes with the ED144 and RK145 Mutations To be Published
5IZH	Lassa virus L protein cap-snatching endonuclease. apo form 分子名称: RNA-directed RNA polymerase L 著者 Reguera, J, Cusack, S. 登録日 2016-03-25 公開日 2016-06-29 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Comparative Structural and Functional Analysis of Bunyavirus and Arenavirus Cap-Snatching Endonucleases. Plos Pathog., 12, 2016
7SFH	SARS-CoV-2 Main Protease (Mpro) in Complex with ML102 分子名称: (1R,2S,5S)-N-{(2S,3R)-4-amino-3-hydroxy-4-oxo-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl}-6,6-dimethyl-3-(3-phenylpropanoyl)-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase, CALCIUM ION 著者 Westberg, M, Fernandez, D, Lin, M.Z. 登録日 2021-10-03 公開日 2022-10-05 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Rational design of a new class of protease inhibitors for the potential treatment of coronavirus diseases To Be Published

<206207208209210211212213214215216217218219220221>