PDB: 41592 件ウェブページステータス検索Chemie searchBIRD

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8D2T	Zebrafish MFSD2A isoform B in inward open ligand-free conformation 分子名称: DODECYL-BETA-D-MALTOSIDE, FAB heavy chain, FAB light chain, ... 著者 Nguyen, C, Lei, H.T, Lai, L.T.F, Gallentino, M.J, Mu, X, Matthies, D, Gonen, T. 登録日 2022-05-30 公開日 2023-05-10 最終更新日 2023-05-24 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Lipid flipping in the omega-3 fatty-acid transporter. Nat Commun, 14, 2023
8D2X	Zebrafish MFSD2A isoform B in inward open ligand 3C conformation 分子名称: DODECYL-BETA-D-MALTOSIDE, FAB heavy chain, FAB light chain, ... 著者 Nguyen, C, Lei, H.T, Lai, L.T.F, Gallentino, M.J, Mu, X, Matthies, D, Gonen, T. 登録日 2022-05-30 公開日 2023-05-10 最終更新日 2023-05-24 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Lipid flipping in the omega-3 fatty-acid transporter. Nat Commun, 14, 2023
8D9H	gRAMP-TPR-CHAT match PFS target RNA(Craspase) 分子名称: CHAT domain protein, PHOSPHATE ION, RAMP superfamily protein, ... 著者 Hu, C, Nam, K.H, Schuler, G, Ke, A. 登録日 2022-06-09 公開日 2023-06-14 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Craspase is a CRISPR RNA-guided, RNA-activated protease. Science, 377, 2022
8D9E	gRAMP-match PFS target 分子名称: RAMP superfamily protein, RNA (36-MER), RNA (5'-R(P*UP*CP*CP*GP*GP*GP*GP*CP*AP*GP*AP*AP*AP*AP*UP*UP*GP*GP*GP*UP*A)-3'), ... 著者 Hu, C, Nam, K.H, Schuler, G, Ke, A. 登録日 2022-06-09 公開日 2023-06-14 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.76 Å) 主引用文献 Craspase is a CRISPR RNA-guided, RNA-activated protease. Science, 377, 2022
6U2K	EM structure of MPEG-1 (L425K, alpha conformation) soluble pre-pore complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Macrophage-expressed gene 1 protein 著者 Pang, S.S, Bayly-Jones, C. 登録日 2019-08-20 公開日 2019-09-25 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (2.93 Å) 主引用文献 The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1. Nat Commun, 10, 2019
8D97	Apo gRAMP 分子名称: RAMP superfamily protein, RNA (42-MER), ZINC ION 著者 Hu, C, Nam, K.H, Schuler, G, Ke, A. 登録日 2022-06-09 公開日 2023-06-14 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Craspase is a CRISPR RNA-guided, RNA-activated protease. Science, 377, 2022
8D9F	gRAMP-TPR-CHAT (Craspase) 分子名称: CHAT domain protein, RAMP superfamily protein, RNA (33-MER), ... 著者 Hu, C, Nam, K.H, Schuler, G, Ke, A. 登録日 2022-06-09 公開日 2023-06-14 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (2.71 Å) 主引用文献 Craspase is a CRISPR RNA-guided, RNA-activated protease. Science, 377, 2022
8D9G	gRAMP-TPR-CHAT Non match PFS target RNA(Craspase) 分子名称: CHAT domain protein, RAMP superfamily protein, RNA (36-MER), ... 著者 Hu, C, Nam, K.H, Schuler, G, Ke, A. 登録日 2022-06-09 公開日 2023-06-14 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (2.57 Å) 主引用文献 Craspase is a CRISPR RNA-guided, RNA-activated protease. Science, 377, 2022
8D9I	gRAMP non-matching PFS-with Mg 分子名称: RAMP superfamily protein, RNA (35-MER), RNA (5'-R(P*UP*CP*CP*GP*GP*GP*GP*CP*AP*GP*AP*AP*AP*AP*UP*UP*GP*GP*A)-3'), ... 著者 Hu, C, Nam, K.H, Schuler, G, Ke, A. 登録日 2022-06-09 公開日 2023-06-14 実験手法 ELECTRON MICROSCOPY (3.62 Å) 主引用文献 Craspase is a CRISPR RNA-guided, RNA-activated protease. Science, 377, 2022
8D0Y	Crystal Structure of HIV-1 BG505 SOSIPv8 Trimer in Complex with CD4bs targeting antibody 21N13 and interface targeting antibody 35O22 at 4.7 Angstrom 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22scFv Heavy Chain Variable, ... 著者 Xian, Y, Wilson, I.A. 登録日 2022-05-26 公開日 2023-07-19 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (4.7 Å) 主引用文献 The domain-swaped dimer of the HIV-1 CD4bs targeting antibody 21N13 To Be Published
8DS5	X-ray structure of the MK5890 Fab - CD27 antibody-antigen complex 分子名称: CADMIUM ION, CD27 antigen, MK-5890 Fab heavy chain, ... 著者 Fischmann, T.O. 登録日 2022-07-21 公開日 2022-09-28 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.926 Å) 主引用文献 Preclinical characterization and clinical translation of pharmacodynamic markers for MK-5890: a human CD27 activating antibody for cancer immunotherapy. J Immunother Cancer, 10, 2022
7OVU	Crystal structure of Arabidopsis thaliana NAT9 in complex with AcCoA 分子名称: ACETYL COENZYME *A, Acyl-CoA N-acyltransferases (NAT) superfamily protein 著者 Layer, D, Weyer, F.A, Kopp, J, Sinning, I. 登録日 2021-06-15 公開日 2022-12-21 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Crystal structure of the Arabidopsis thaliana N-acetyltransferase 9 To Be Published
7PHG	MaP OF P5C3RBD Interface 分子名称: Heavy ChaIn variable, Light ChaIn, Surface glycoprotein 著者 Perez, L. 登録日 2021-08-17 公開日 2021-10-13 最終更新日 2021-10-27 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 A highly potent antibody effective against SARS-CoV-2 variants of concern. Cell Rep, 37, 2021
4TSX	HIV-1 Integrase Catalytic Core Domain Mutant Complexed with Allosteric Inhibitor 分子名称: (2S)-tert-butoxy[4-(3,4-dihydro-2H-chromen-6-yl)-2-methylquinolin-3-yl]ethanoic acid, Integrase, SULFATE ION 著者 Feng, L, Kvaratskhelia, M. 登録日 2014-06-19 公開日 2014-12-17 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 The mechanism of H171T resistance reveals the importance of N -protonated His171 for the binding of allosteric inhibitor BI-D to HIV-1 integrase. Retrovirology, 11, 2014
7Q03	Ketol-acid reductoisomerase from Methanothermococcus thermolithotrophicus in the close state with NADP and Mg2+ 分子名称: 1,2-ETHANEDIOL, 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL, GLYCEROL, ... 著者 Lemaire, O.N, Mueller, M, Wagner, T. 登録日 2021-10-14 公開日 2021-12-08 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural Rearrangements of a Dodecameric Ketol-Acid Reductoisomerase Isolated from a Marine Thermophilic Methanogen. Biomolecules, 11, 2021
7Q07	Ketol-acid reductoisomerase from Methanothermococcus thermolithotrophicus in the open state with NADP and tartrate 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Ketol-Acid Reductoisomerase from Methanothermococcus thermolithotrophicus, ... 著者 Lemaire, O.N, Mueller, M, Wagner, T. 登録日 2021-10-14 公開日 2021-12-08 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural Rearrangements of a Dodecameric Ketol-Acid Reductoisomerase Isolated from a Marine Thermophilic Methanogen. Biomolecules, 11, 2021
5FWP	Atomic cryoEM structure of Hsp90-Cdc37-Cdk4 complex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CYCLIN-DEPENDENT KINASE 4, HEAT SHOCK PROTEIN HSP 90 BETA, ... 著者 Verba, K.A, Wang, R.Y.R, Arakawa, A, Liu, Y, Yokoyama, S, Agard, D.A. 登録日 2016-02-18 公開日 2016-10-26 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (7.2 Å) 主引用文献 Atomic Structure of Hsp90:Cdc37:Cdk4 Reveals that Hsp90 Traps and Stabilizes an Unfolded Kinase. Science, 352, 2016
2FYL	Haddock model of the complex between double module of LRP, CR56, and first domain of receptor associated protein, RAP-d1. 分子名称: Alpha-2-macroglobulin receptor-associated protein, CALCIUM ION, Low-density lipoprotein receptor-related protein 1 著者 Jensen, G.A, Andersen, O.M, Bonvin, A.M, Bjerrum-Bohr, I, Etzerodt, M, O'shea, C, Poulsen, F.M, Kragelund, B.B. 登録日 2006-02-08 公開日 2006-10-10 最終更新日 2022-03-09 実験手法 SOLUTION NMR 主引用文献 Binding Site Structure of One LRP-RAP Complex:Implications for a Common Ligand-Receptor Binding Motif. J.Mol.Biol., 362, 2006
7Q39	Ribonucleotide Reductase R2_genomic protein from Aquifex aeolicus 分子名称: FE (III) ION, Ribonucleoside-diphosphate reductase subunit beta 著者 Scaletti, E, Rehling, D, Stenmark, P. 登録日 2021-10-27 公開日 2022-04-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural and Biochemical Investigation of Class I Ribonucleotide Reductase from the Hyperthermophile Aquifex aeolicus. Biochemistry, 61, 2022
1BA5	DNA-BINDING DOMAIN OF HUMAN TELOMERIC PROTEIN, HTRF1, NMR, 18 STRUCTURES 分子名称: HTRF1 著者 Nishikawa, T, Nagadoi, A, Yoshimura, S, Aimoto, S, Nishimura, Y. 登録日 1998-04-22 公開日 1999-04-27 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structure of the DNA-binding domain of human telomeric protein, hTRF1. Structure, 6, 1998
7Q3C	Ribonucleotide Reductase AaR2 protein from Aquifex aeolicus 分子名称: FE (III) ION, Ribonucleoside-diphosphate reductase subunit beta 著者 Scaletti, E.R, Rehling, D, Stenmark, P. 登録日 2021-10-27 公開日 2022-04-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structural and Biochemical Investigation of Class I Ribonucleotide Reductase from the Hyperthermophile Aquifex aeolicus. Biochemistry, 61, 2022
7B93	Cryo-EM structure of mitochondrial complex I from Mus musculus inhibited by IACS-2858 at 3.0 A 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 1-[[3-(4-methylsulfonylpiperidin-1-yl)phenyl]methyl]-5-[3-[4-(trifluoromethyloxy)phenyl]-1,2,4-oxadiazol-5-yl]pyridin-2-one, ... 著者 Chung, I, Hirst, J. 登録日 2020-12-14 公開日 2021-05-26 実験手法 ELECTRON MICROSCOPY (3.04 Å) 主引用文献 Cork-in-bottle mechanism of inhibitor binding to mammalian complex I. Sci Adv, 7, 2021
8G7U	Cryo-EM structure of Riplet:RIG-I:dsRNA complex (end-semi-closed end) 分子名称: Antiviral innate immune response receptor RIG-I, E3 ubiquitin-protein ligase RNF135, ZINC ION, ... 著者 Wang, W, Pyle, A.M. 登録日 2023-02-17 公開日 2023-11-15 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 The E3 ligase Riplet promotes RIG-I signaling independent of RIG-I oligomerization. Nat Commun, 14, 2023
8G7T	Cryo-EM structure of Riplet:RIG-I:dsRNA complex (end-end) 分子名称: Antiviral innate immune response receptor RIG-I, E3 ubiquitin-protein ligase RNF135, ZINC ION, ... 著者 Wang, W, Pyle, A.M. 登録日 2023-02-17 公開日 2023-11-15 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 The E3 ligase Riplet promotes RIG-I signaling independent of RIG-I oligomerization. Nat Commun, 14, 2023
8G7V	Cryo-EM structure of Riplet:RIG-I:dsRNA complex (end-inter) 分子名称: Antiviral innate immune response receptor RIG-I, E3 ubiquitin-protein ligase RNF135, ZINC ION, ... 著者 Wang, W, Pyle, A.M. 登録日 2023-02-17 公開日 2023-11-15 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 The E3 ligase Riplet promotes RIG-I signaling independent of RIG-I oligomerization. Nat Commun, 14, 2023

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