PDB: 527 件ウェブページステータス検索Chemie searchBIRD

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3EMN	The Crystal Structure of Mouse VDAC1 at 2.3 A resolution 分子名称: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Voltage-dependent anion-selective channel protein 1 著者 Ujwal, R, Cascio, D, Colletier, J.-P, Faham, S, Zhang, J, Toro, L, Ping, P, Abramson, J. 登録日 2008-09-24 公開日 2008-12-16 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The crystal structure of mouse VDAC1 at 2.3 A resolution reveals mechanistic insights into metabolite gating Proc.Natl.Acad.Sci.USA, 105, 2008
7MSS	Human E105Qa GTP-specific succinyl-CoA synthetase complexed with succinate, magnesium ion and CoA 分子名称: COENZYME A, GLYCEROL, MAGNESIUM ION, ... 著者 Huang, J, Fraser, M.E. 登録日 2021-05-12 公開日 2022-10-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 The structure of succinyl-CoA synthetase bound to the succinyl-phosphate intermediate clarifies the catalytic mechanism of ATP-citrate lyase Acta Crystallogr.,Sect.F, 78, 2022
7MSR	Human E105Qa GTP-specific succinyl-CoA synthetase complexed with succinyl-phosphate, magnesium ion and desulfo-coenzyme A 分子名称: 1,2-ETHANEDIOL, 4-oxo-4-(phosphonooxy)butanoic acid, DESULFO-COENZYME A, ... 著者 Huang, J, Fraser, M.E. 登録日 2021-05-12 公開日 2022-10-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 The structure of succinyl-CoA synthetase bound to the succinyl-phosphate intermediate clarifies the catalytic mechanism of ATP-citrate lyase Acta Crystallogr.,Sect.F, 78, 2022
2QLF	Crystal Structure of Caspase-7 with inhibitor AC-DNLD-CHO 分子名称: Caspase-7, Inhibitor AC-DNLD-CHO, Peptide QGHGE 著者 Agniswamy, J, Fang, B, Weber, I. 登録日 2007-07-12 公開日 2007-08-28 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Plasticity of S2-S4 specificity pockets of executioner caspase-7 revealed by structural and kinetic analysis. Febs J., 274, 2007
2E2A	ASP81LEU ENZYME IIA FROM THE LACTOSE SPECIFIC PTS FROM LACTOCOCCUS LACTIS 分子名称: PROTEIN (ENZYME IIA) 著者 Sliz, P, Koch, B, Hengstenberg, W, Pai, E.F. 登録日 1999-05-14 公開日 2003-06-17 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of Asp81Leu Enzyme Iia from the Lactose Specific Pts from Lactococcus Lactis To be Published
2QLJ	Crystal Structure of Caspase-7 with Inhibitor AC-WEHD-CHO 分子名称: CITRIC ACID, Caspase-7, Inhibitor AC-WEHD-CHO, ... 著者 Agniswamy, J, Fang, B, Weber, I. 登録日 2007-07-12 公開日 2007-08-28 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Plasticity of S2-S4 specificity pockets of executioner caspase-7 revealed by structural and kinetic analysis. Febs J., 274, 2007
8J0O	cryo-EM structure of human EMC and VDAC 分子名称: ER membrane protein complex subunit 1, ER membrane protein complex subunit 10, ER membrane protein complex subunit 2, ... 著者 Li, M, Zhang, C, Wu, J, Lei, M. 登録日 2023-04-11 公開日 2024-04-03 最終更新日 2024-04-17 実験手法 ELECTRON MICROSCOPY (3.32 Å) 主引用文献 Structural insights into human EMC and its interaction with VDAC. Aging (Albany NY), 16, 2024
4HQ0	Crystal Structure of mutant form of Caspase-7 分子名称: Caspase-7 著者 Lee, Y, Kang, H.J, Bae, K.-H, Kim, S.J, Chung, S.J. 登録日 2012-10-25 公開日 2013-09-11 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural asymmetry of procaspase-7 bound to a specific inhibitor Acta Crystallogr.,Sect.D, 69, 2013
4JB8	Caspase-7 in Complex with DARPin C7_16 分子名称: Caspase-7 subunit p11, Caspase-7 subunit p20, DARPin C7_16 著者 Fluetsch, A, Seeger, M.A, Gruetter, M.G. 登録日 2013-02-19 公開日 2013-08-21 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Design, construction, and characterization of a second-generation DARPin library with reduced hydrophobicity. Protein Sci., 22, 2013
4JR2	Human procaspase-7/caspase-7 heterodimer bound to Ac-DEVD-CMK 分子名称: Ac-DEVD-CMK, CHLORIDE ION, Procaspase-7 著者 Thomsen, N.D, Wells, J.A. 登録日 2013-03-20 公開日 2013-05-08 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structural snapshots reveal distinct mechanisms of procaspase-3 and -7 activation. Proc.Natl.Acad.Sci.USA, 110, 2013
4JJ8	Caspase-3 specific unnatural amino acid peptides 分子名称: Caspase Inhibitor, Caspase-7 著者 Vickers, C.J, Gonzalez-Paez, G.E, Wolan, D.W. 登録日 2013-03-07 公開日 2013-06-12 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.937 Å) 主引用文献 Selective Detection of Caspase-3 versus Caspase-7 Using Activity-Based Probes with Key Unnatural Amino Acids. Acs Chem.Biol., 8, 2013
4JR1	Human procaspase-7 bound to Ac-DEVD-CMK 分子名称: Ac-DEVD-CMK, CHLORIDE ION, Procaspase-7 著者 Thomsen, N.D, Wells, J.A. 登録日 2013-03-20 公開日 2013-05-08 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.149 Å) 主引用文献 Structural snapshots reveal distinct mechanisms of procaspase-3 and -7 activation. Proc.Natl.Acad.Sci.USA, 110, 2013
4LSZ	Caspase-7 in Complex with DARPin D7.18 分子名称: Caspase-7 subunit p10, Caspase-7 subunit p20, DARPin D7.18 著者 Fluetsch, A, Lukarska, M, Gruetter, M.G. 登録日 2013-07-23 公開日 2014-07-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Combined inhibition of caspase 3 and caspase 7 by two highly selective DARPins slows down cellular demise. Biochem.J., 461, 2014
4ZVR	Caspase-7 Variant 4 (V4) with reprogrammed substrate specificity due to Y230V/W232Y/S234V/Q276D substitutions bound to DEVD inhibitor. 分子名称: Caspase-7, Peptide ACE-ASP-GLU-VAL-ASJ 著者 Hill, M.E, MacPherson, D.J, Hardy, J.A. 登録日 2015-05-18 公開日 2016-04-20 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Reprogramming Caspase-7 Specificity by Regio-Specific Mutations and Selection Provides Alternate Solutions for Substrate Recognition. Acs Chem.Biol., 11, 2016
3IBF	Crystal structure of unliganded caspase-7 分子名称: Caspase-7 著者 Agniswamy, J. 登録日 2009-07-15 公開日 2009-09-01 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Conformational similarity in the activation of caspase-3 and -7 revealed by the unliganded and inhibited structures of caspase-7. Apoptosis, 14, 2009
4ZVU	Caspase-7 wild-type bound to the caspase-6 cognate tetrapeptide inhibitor Ac-VEID-cho 分子名称: Caspase-7, Tetrapeptide Inhibitor Ac-VEID-CHO 著者 Hardy, J.A, MacPherson, D.J, Hill, M.E. 登録日 2015-05-18 公開日 2016-04-20 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.601 Å) 主引用文献 Reprogramming Caspase-7 Specificity by Regio-Specific Mutations and Selection Provides Alternate Solutions for Substrate Recognition. Acs Chem.Biol., 11, 2016
4ZVQ	Caspase-7 Variant 2 (V2) with reprogrammed substrate specificity due to Y230V/W232M/Q276C substitutions bound to VEID inhibitor. 分子名称: Caspase-7, Peptide ACE-VAL-GLU-ILE-ASA 著者 Hill, M.E, MacPherson, D.J, Hardy, J.A. 登録日 2015-05-18 公開日 2016-04-20 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Reprogramming Caspase-7 Specificity by Regio-Specific Mutations and Selection Provides Alternate Solutions for Substrate Recognition. Acs Chem.Biol., 11, 2016
3R5K	A designed redox-controlled caspase-7 分子名称: Caspase-7, FORMIC ACID 著者 Witkowski, W.A, Hardy, J.A. 登録日 2011-03-18 公開日 2011-06-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.86 Å) 主引用文献 A designed redox-controlled caspase. Protein Sci., 20, 2011
3H1P	Mature Caspase-7 I213A with DEVD-CHO inhibitor bound to active site 分子名称: Caspase-7, N-ACETYL-L-ALPHA-ASPARTYL-L-ALPHA-GLUTAMYL-N-[(2S)-1-CARBOXY-3-HYDROXYPROPAN-2-YL]-L-VALINAMIDE 著者 Witkowski, W.A, Hardy, J.A. 登録日 2009-04-13 公開日 2009-06-30 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 L2' loop is critical for caspase-7 active site formation. Protein Sci., 18, 2009
3RNT	CRYSTAL STRUCTURE OF GUANOSINE-FREE RIBONUCLEASE T1, COMPLEXED WITH VANADATE(V), SUGGESTS CONFORMATIONAL CHANGE UPON SUBSTRATE BINDING 分子名称: CALCIUM ION, RIBONUCLEASE T1, VANADATE ION 著者 Kostrewa, D, Choe, H.-W, Heinemann, U, Saenger, W. 登録日 1989-05-31 公開日 1989-10-15 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of guanosine-free ribonuclease T1, complexed with vanadate (V), suggests conformational change upon substrate binding. Biochemistry, 28, 1989
3IBC	Crystal Structure of Caspase-7 incomplex with Acetyl-YVAD-CHO 分子名称: Acetyl-YVAD-CHO, Caspase-7 著者 Agniswamy, J. 登録日 2009-07-15 公開日 2009-09-01 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Conformational similarity in the activation of caspase-3 and -7 revealed by the unliganded and inhibited structures of caspase-7. Apoptosis, 14, 2009
4ZVT	Caspase-7 Variant 1 (V1) with reprogrammed substrate specificity due to Y230A/W232M/S234N substitutions, bound to VEID inhibitor. 分子名称: Caspase-7, VEID inhibitor 著者 Hardy, J.A, MacPherson, D.J, Hill, M.E. 登録日 2015-05-18 公開日 2016-04-20 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Reprogramming Caspase-7 Specificity by Regio-Specific Mutations and Selection Provides Alternate Solutions for Substrate Recognition. Acs Chem.Biol., 11, 2016
4ZVP	Caspase-7 Variant 2 (V2) with reprogrammed substrate specificity due to Y230V/W232M/Q276C substitutions bound to DEVD inhibitor. 分子名称: Caspase-7, Peptide ACE-ASP-GLU-VAL-ASA 著者 Hill, M.E, MacPherson, D.J, Hardy, J.A. 登録日 2015-05-18 公開日 2016-04-20 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Reprogramming Caspase-7 Specificity by Regio-Specific Mutations and Selection Provides Alternate Solutions for Substrate Recognition. Acs Chem.Biol., 11, 2016
4ZVS	Caspase-7 Variant 1 (V1) with reprogrammed substrate specificity due to Y230A/W232M/S234N substitutions, bound to DEVD inhibitor. 分子名称: Caspase-7, DEVD inhibitor 著者 MacPherson, D.J, Hill, M.E, Hardy, J.A. 登録日 2015-05-18 公開日 2016-04-20 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Reprogramming Caspase-7 Specificity by Regio-Specific Mutations and Selection Provides Alternate Solutions for Substrate Recognition. Acs Chem.Biol., 11, 2016
4ZVO	Caspase-7 Variant 4 (V4) with reprogrammed substrate specificity due to Y230V/W232Y/S234V/Q276D substitutions bound to VEID inhibitor. 分子名称: Caspase-7, Peptide ACE-VAL-GLU-ILE-ASJ 著者 Hill, M.E, MacPherson, D.J, Hardy, J.A. 登録日 2015-05-18 公開日 2016-04-20 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Reprogramming Caspase-7 Specificity by Regio-Specific Mutations and Selection Provides Alternate Solutions for Substrate Recognition. Acs Chem.Biol., 11, 2016

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