6AJM
 
 | | Crystal structure of apo AtaTR | | 分子名称: | DUF1778 domain-containing protein, N-acetyltransferase, TRIETHYLENE GLYCOL | | 著者 | Yashiro, Y, Yamashita, S, Tomita, K. | | 登録日 | 2018-08-28 | | 公開日 | 2019-01-02 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.604 Å) | | 主引用文献 | Crystal Structure of the Enterohemorrhagic Escherichia coli AtaT-AtaR Toxin-Antitoxin Complex.
Structure, 27, 2019
|
|
6OJS
 | | Crystal structure of TS-DHFR from Cryptosporidium hominis in complex with NADPH, FdUMP, MTX and 2-amino-4-oxo-4,7-dihydro-pyrrolo[2,3-d]pyrimidine-methyl-phenyl-D-glutamic acid | | 分子名称: | 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, Bifunctional dihydrofolate reductase-thymidylate synthase, METHOTREXATE, ... | | 著者 | Czyzyk, D.J, Anderson, K.S, Jorgensen, W.L, Valhondo, M. | | 登録日 | 2019-04-12 | | 公開日 | 2019-06-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.214 Å) | | 主引用文献 | Understanding the structural basis of species selective, stereospecific inhibition for Cryptosporidium and human thymidylate synthase.
Febs Lett., 593, 2019
|
|
1U0U
 | | An Aldol Switch Discovered in Stilbene Synthases Mediates Cyclization Specificity of Type III Polyketide Synthases: Pine stilbene synthase structure | | 分子名称: | Dihydropinosylvin synthase | | 著者 | Austin, M.B, Bowman, M.E, Ferrer, J.-L, Schroder, J, Noel, J.P. | | 登録日 | 2004-07-14 | | 公開日 | 2004-10-12 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | | 主引用文献 | An Aldol Switch Discovered in Stilbene Synthases Mediates Cyclization Specificity of Type III Polyketide Synthases
Chem.Biol., 11, 2004
|
|
4HNY
 | | Apo N-terminal acetyltransferase complex A | | 分子名称: | GLYCEROL, N-terminal acetyltransferase A complex catalytic subunit ARD1, N-terminal acetyltransferase A complex subunit NAT1, ... | | 著者 | Neubauer, J.L, Immormino, R.M, Dollins, D.E, Endo-Streeter, S.T, Pemble IV, C.W, York, J.D. | | 登録日 | 2012-10-21 | | 公開日 | 2014-03-26 | | 実験手法 | X-RAY DIFFRACTION (2.249 Å) | | 主引用文献 | The Protein Complex NatA Binds Inositol Hexakisphosphate and Exhibits Conformational Flexibility
To be Published
|
|
6ACS
 | | poly-cis-prenyltransferase | | 分子名称: | CITRIC ACID, Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific), GLYCEROL, ... | | 著者 | Ko, T.-P, Chen, Y. | | 登録日 | 2018-07-27 | | 公開日 | 2018-12-19 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Structure of undecaprenyl pyrophosphate synthase from Acinetobacter baumannii
Acta Crystallogr F Struct Biol Commun, 74, 2018
|
|
6AG5
 | |
1J3I
 | | Wild-type Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with WR99210, NADPH, and dUMP | | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 6,6-DIMETHYL-1-[3-(2,4,5-TRICHLOROPHENOXY)PROPOXY]-1,6-DIHYDRO-1,3,5-TRIAZINE-2,4-DIAMINE, Bifunctional dihydrofolate reductase-thymidylate synthase, ... | | 著者 | Yuvaniyama, J, Chitnumsub, P, Kamchonwongpaisan, S, Vanichtanankul, J, Sirawaraporn, W, Taylor, P, Walkinshaw, M, Yuthavong, Y. | | 登録日 | 2003-02-03 | | 公開日 | 2003-05-06 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | | 主引用文献 | Insights into antifolate resistance from malarial DHFR-TS structures.
NAT.STRUCT.BIOL., 10, 2003
|
|
1TSX
 | | THYMIDYLATE SYNTHASE R179E MUTANT | | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE | | 著者 | Finer-Moore, J, Stroud, R.M. | | 登録日 | 1995-12-05 | | 公開日 | 1996-03-08 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Contribution of a salt bridge to binding affinity and dUMP orientation to catalytic rate: mutation of a substrate-binding arginine in thymidylate synthase.
Protein Eng., 9, 1996
|
|
1IXQ
 | | Enzyme-Phosphate2 Complex of Pyridoxine 5'-Phosphate synthase | | 分子名称: | PHOSPHATE ION, Pyridoxine 5'-phosphate Synthase | | 著者 | Garrido-Franco, M, Laber, B, Huber, R, Clausen, T. | | 登録日 | 2002-06-28 | | 公開日 | 2003-02-11 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Enzyme-ligand complexes of pyridoxine 5'-phosphate synthase: implications for substrate binding and catalysis
J.MOL.BIOL., 321, 2002
|
|
1U7N
 | | Crystal Structure of the fatty acid/phospholipid synthesis protein PlsX from Enterococcus faecalis V583 | | 分子名称: | 1,2-ETHANEDIOL, ETHANOL, Fatty acid/phospholipid synthesis protein plsX | | 著者 | Kim, Y, Li, H, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2004-08-04 | | 公開日 | 2004-08-17 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Crystal structure of fatty acid/phospholipid synthesis protein PlsX from Enterococcus faecalis.
J.STRUCT.FUNCT.GENOM., 10, 2009
|
|
6ORA
 | | An Unexpected Intermediate in the Reaction Catalyzed by Quinolinate Synthase | | 分子名称: | (2~{Z})-2-(1-oxidanyl-3-oxidanylidene-propyl)iminobutanedioic acid, 2-hydroxy-N-[(1S)-1-hydroxy-3-oxopropyl]-L-aspartic acid, ACETATE ION, ... | | 著者 | Esakova, O.A, Grove, T.L, Silakov, A, Yennawar, N.H, Booker, S.J. | | 登録日 | 2019-04-29 | | 公開日 | 2019-08-21 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | An Unexpected Species Determined by X-ray Crystallography that May Represent an Intermediate in the Reaction Catalyzed by Quinolinate Synthase.
J.Am.Chem.Soc., 141, 2019
|
|
6OTW
 | | Crystallographic Structure of (HbII-HbIII)-O2 from Lucina pectinata at pH 5.0 | | 分子名称: | Hemoglobin II, Hemoglobin III, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Marchany-Rivera, D, Smith, C.A, Rodriguez-Perez, J.D, Lopez-Garriga, J. | | 登録日 | 2019-05-03 | | 公開日 | 2020-04-01 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.447 Å) | | 主引用文献 | Lucina pectinata oxyhemoglobin (II-III) heterodimer pH susceptibility.
J.Inorg.Biochem., 207, 2020
|
|
6OTY
 | | Crystallographic Structure of (HbII-HbIII)-O2 from Lucina pectinata at pH 4.0 | | 分子名称: | Hemoglobin II, Hemoglobin III, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Marchany-Rivera, D, Smith, C.A, Rodriguez-Perez, J.D, Lopez-Garriga, J. | | 登録日 | 2019-05-03 | | 公開日 | 2020-04-01 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.598 Å) | | 主引用文献 | Lucina pectinata oxyhemoglobin (II-III) heterodimer pH susceptibility.
J.Inorg.Biochem., 207, 2020
|
|
4LX9
 | |
1IJD
 | | Crystallographic Structure of the LH3 Complex from Rhodopseudomonas acidophila strain 7050 | | 分子名称: | BACTERIOCHLOROPHYLL A, LIGHT-HARVESTING PROTEIN B-800/820, ALPHA CHAIN, ... | | 著者 | McLuskey, K, Prince, S.M, Cogdell, R.J, Isaacs, N.W. | | 登録日 | 2001-04-25 | | 公開日 | 2001-10-17 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | The crystallographic structure of the B800-820 LH3 light-harvesting complex from the purple bacteria Rhodopseudomonas acidophila strain 7050.
Biochemistry, 40, 2001
|
|
2Z0Z
 | | Crystal structure of putative acetyltransferase | | 分子名称: | Putative uncharacterized protein TTHA1799, SULFATE ION | | 著者 | Murayama, K, Kato-Murayama, M, Terada, T, Kuramitsu, S, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-05-07 | | 公開日 | 2007-11-13 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Genetic Encoding of 3-Iodo-l-Tyrosine in Escherichia coli for Single-Wavelength Anomalous Dispersion Phasing in Protein Crystallography
Structure, 17, 2009
|
|
4HO1
 | |
6AOG
 | | Crystal structure of Toxoplasma gondii TS-DHFR complexed with NADPH, dUMP, PDDF, and 5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine (pyrimethamine) | | 分子名称: | 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 5-(4-CHLORO-PHENYL)-6-ETHYL-PYRIMIDINE-2,4-DIAMINE, ... | | 著者 | Thomas, S.B, Li, Y, Chen, Z, Lu, H. | | 登録日 | 2017-08-16 | | 公開日 | 2018-08-22 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Identification of selective, brain penetrant Toxoplasma gondii dihydrofolate reductase inhibitors for the treatment of toxoplasmosis
To Be Published
|
|
5X4Y
 | | Mutant human thymidylate synthase M190K crystallized in a sulfate-containing condition | | 分子名称: | SULFATE ION, Thymidylate synthase | | 著者 | Chen, D, Jansson, A, Larsson, A, Nordlund, P. | | 登録日 | 2017-02-14 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural analyses of human thymidylate synthase reveal a site that may control conformational switching between active and inactive states
J. Biol. Chem., 292, 2017
|
|
1UFH
 | | Structure of putative acetyltransferase, YYCN protein of Bacillus subtilis | | 分子名称: | YYCN protein | | 著者 | Taneja, B, Maar, S, Shuvalova, L, Collart, F.R, Anderson, W, Mondragon, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2003-05-29 | | 公開日 | 2003-06-24 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of the bacillus subtilis YYCN protein: a putative N-acetyltransferase
Proteins, 53, 2003
|
|
5X5Q
 | | Human thymidylate synthase complexed with dUMP and raltitrexed | | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, TOMUDEX, Thymidylate synthase | | 著者 | Chen, D, Jansson, A, Larsson, A, Nordlund, P. | | 登録日 | 2017-02-17 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | | 主引用文献 | Structural analyses of human thymidylate synthase reveal a site that may control conformational switching between active and inactive states
J. Biol. Chem., 292, 2017
|
|
6ARR
 | | Aspergillus fumigatus Cytosolic Thiolase: Apo enzyme in complex with cesium ions | | 分子名称: | Acetyl-CoA acetyltransferase, CESIUM ION, CHLORIDE ION, ... | | 著者 | Marshall, A.C, Bond, C.S, Bruning, J.B. | | 登録日 | 2017-08-23 | | 公開日 | 2018-05-30 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.822 Å) | | 主引用文献 | Structure of Aspergillus fumigatus Cytosolic Thiolase: Trapped Tetrahedral Reaction Intermediates and Activation by Monovalent Cations
Acs Catalysis, 8(3), 2018
|
|
5XA2
 | |
1J3K
 | | Quadruple mutant (N51I+C59R+S108N+I164L) Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with WR99210, NADPH, and dUMP | | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 6,6-DIMETHYL-1-[3-(2,4,5-TRICHLOROPHENOXY)PROPOXY]-1,6-DIHYDRO-1,3,5-TRIAZINE-2,4-DIAMINE, Bifunctional dihydrofolate reductase-thymidylate synthase, ... | | 著者 | Yuvaniyama, J, Chitnumsub, P, Kamchonwongpaisan, S, Vanichtanankul, J, Sirawaraporn, W, Taylor, P, Walkinshaw, M, Yuthavong, Y. | | 登録日 | 2003-02-03 | | 公開日 | 2003-05-06 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Insights into antifolate resistance from malarial DHFR-TS structures.
NAT.STRUCT.BIOL., 10, 2003
|
|
5XNH
 | | Crystal structure of the branched-chain polyamine synthase (BpsA) in complex with spermidine | | 分子名称: | FE (III) ION, N(4)-bis(aminopropyl)spermidine synthase, SPERMIDINE | | 著者 | Mizohata, E, Tse, K.M, Fujita, J, Inoue, T. | | 登録日 | 2017-05-22 | | 公開日 | 2017-10-04 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Active site geometry of a novel aminopropyltransferase for biosynthesis of hyperthermophile-specific branched-chain polyamine.
FEBS J., 284, 2017
|
|
