PDB: 10243 件ウェブページステータス検索Chemie searchBIRD

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8K9I	Structure of CUL3-RBX1-KLHL22 complex without CUL3 NA motif 分子名称: Cullin-3, E3 ubiquitin-protein ligase RBX1, N-terminally processed, ... 著者 Wang, W, Ling, L, Dai, Z, Zuo, P, Yin, Y. 登録日 2023-08-01 公開日 2024-05-29 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 A conserved N-terminal motif of CUL3 contributes to assembly and E3 ligase activity of CRL3 KLHL22. Nat Commun, 15, 2024
8JE1	An asymmetry dimer of the Cul2-Rbx1-EloBC-FEM1B ubiquitin ligase complexed with BEX2 分子名称: Cullin-2, E3 ubiquitin-protein ligase RBX1, Elongin-B, ... 著者 Dai, Z, Liang, L, Yin, Y.X. 登録日 2023-05-15 公開日 2024-02-28 最終更新日 2024-04-03 実験手法 ELECTRON MICROSCOPY (3.95 Å) 主引用文献 Structural insights into the ubiquitylation strategy of the oligomeric CRL2 FEM1B E3 ubiquitin ligase. Embo J., 43, 2024
7QTM	Transition state analogue of small G protein in complex with relevant GAP 分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Rho GTPase-activating protein 1, ... 著者 Baumann, P, Jin, Y. 登録日 2022-01-14 公開日 2023-01-25 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Transition state analogue of small G protein in complex with relevant GAP To Be Published
8RQM	Alpha-synuclein amyloid fibrils 分子名称: Alpha-synuclein 著者 Saibil, H.R, Monistrol, J. 登録日 2024-01-18 公開日 2024-02-28 最終更新日 2025-04-16 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Stepwise recruitment of chaperone Hsc70 by DNAJB1 produces ordered arrays primed for bursts of amyloid fibril disassembly. Commun Biol, 8, 2025
8RRR	Alpha-synuclein amyloid fibril 分子名称: Alpha-synuclein 著者 Saibil, H.R, Monistrol, J. 登録日 2024-01-23 公開日 2024-02-28 最終更新日 2025-04-16 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Stepwise recruitment of chaperone Hsc70 by DNAJB1 produces ordered arrays primed for bursts of amyloid fibril disassembly. Commun Biol, 8, 2025
8RI9	Late alpha-Synuclein fibril structure from liquid-liquid phase separations. 分子名称: Alpha-synuclein 著者 De Simone, A, Barritt, J.D, Chen, S, Cascella, R, Cecchi, C, Bigi, A, Jarvis, J.A, Chiti, F, Dobson, C.M, Fusco, G. 登録日 2023-12-18 公開日 2024-03-06 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structure-Toxicity Relationship in Intermediate Fibrils from alpha-Synuclein Condensates. J.Am.Chem.Soc., 146, 2024
7PC5	The third PDZ domain of PDZD7 complexed with the PDZ-binding motif of EXOC4 分子名称: CALCIUM ION, Exocyst complex component 4, GLYCEROL, ... 著者 Cousido-Siah, A, Trave, G, Gogl, G. 登録日 2021-08-03 公開日 2022-04-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 A scalable strategy to solve structures of PDZ domains and their complexes. Acta Crystallogr D Struct Biol, 78, 2022
7PC4	The PDZ domain of SNTB1 complexed with the PDZ-binding motif of HTLV1-TAX1 分子名称: 1,2-ETHANEDIOL, Beta-1-syntrophin,Annexin A2, CALCIUM ION, ... 著者 Cousido-Siah, A, Trave, G, Gogl, G. 登録日 2021-08-03 公開日 2022-04-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 A scalable strategy to solve structures of PDZ domains and their complexes. Acta Crystallogr D Struct Biol, 78, 2022
7PC8	The PDZ domain of SNTG1 complexed with the phosphomimetic mutant PDZ-binding motif of RSK1 分子名称: CALCIUM ION, GLYCEROL, Gamma-1-syntrophin,Annexin A2, ... 著者 Cousido-Siah, A, Trave, G, Gogl, G. 登録日 2021-08-03 公開日 2022-04-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A scalable strategy to solve structures of PDZ domains and their complexes. Acta Crystallogr D Struct Biol, 78, 2022
7PCB	The PDZ domain of SNX27 fused with ANXA2 分子名称: CALCIUM ION, GLYCEROL, Sorting nexin-27,Annexin A2 著者 Cousido-Siah, A, Trave, G, Gogl, G. 登録日 2021-08-03 公開日 2022-04-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A scalable strategy to solve structures of PDZ domains and their complexes. Acta Crystallogr D Struct Biol, 78, 2022
7PC7	The PDZ domain of SNTG1 complexed with the acetylated PDZ-binding motif of PTEN 分子名称: CALCIUM ION, GLYCEROL, Gamma-1-syntrophin,Annexin A2, ... 著者 Cousido-Siah, A, Trave, G, Gogl, G. 登録日 2021-08-03 公開日 2022-04-20 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 A scalable strategy to solve structures of PDZ domains and their complexes. Acta Crystallogr D Struct Biol, 78, 2022
7PC9	The PDZ domain of SYNJ2BP complexed with the PDZ-binding motif of HTLV1-TAX1 分子名称: CALCIUM ION, Protein Tax-1, Synaptojanin-2-binding protein,Annexin A2 著者 Cousido-Siah, A, Trave, G, Gogl, G. 登録日 2021-08-03 公開日 2022-04-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 A scalable strategy to solve structures of PDZ domains and their complexes. Acta Crystallogr D Struct Biol, 78, 2022
7PC3	The second PDZ domain of DLG1 complexed with the PDZ-binding motif of HTLV1-TAX1 分子名称: CALCIUM ION, Disks large homolog 1,Annexin A2, GLYCEROL, ... 著者 Cousido-Siah, A, Trave, G, Gogl, G. 登録日 2021-08-03 公開日 2022-04-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 A scalable strategy to solve structures of PDZ domains and their complexes. Acta Crystallogr D Struct Biol, 78, 2022
7EZP	Indole-2-carboxylic acid derivatives as allosteric inhibitors of fructose-1,6-bisphosphatase 分子名称: 1,6-di-O-phosphono-beta-D-fructofuranose, 3-(3-hydroxy-3-oxopropyl)-5-(2-methylpropyl)-7-nitro-1H-indole-2-carboxylic acid, Fructose-1,6-bisphosphatase 1 著者 Wang, X.Y, Zhou, J, Xu, B.L. 登録日 2021-06-01 公開日 2022-06-01 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Discovery of Novel Indole Derivatives as Fructose-1,6-bisphosphatase Inhibitors and X-ray Cocrystal Structures Analysis. Acs Med.Chem.Lett., 13, 2022
7EZR	Indole-2-carboxylic acid derivatives as allosteric inhibitors of fructose-1,6-bisphosphatase 分子名称: 1,6-di-O-phosphono-beta-D-fructofuranose, 5-ethyl-7-nitro-3-[3-oxidanylidene-3-(thiophen-2-ylsulfonylamino)propyl]-1H-indole-2-carboxylic acid, Fructose-1,6-bisphosphatase 1 著者 Wang, X.Y, Zhou, J, Xu, B.L. 登録日 2021-06-01 公開日 2022-06-01 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.27 Å) 主引用文献 Discovery of Novel Indole Derivatives as Fructose-1,6-bisphosphatase Inhibitors and X-ray Cocrystal Structures Analysis. Acs Med.Chem.Lett., 13, 2022
7EZF	Indole-2-carboxylic acid derivatives as allosteric inhibitors of fructose-1,6-bisphosphatase 分子名称: 1,6-di-O-phosphono-beta-D-fructofuranose, 7-chloranyl-5-ethyl-3-(3-hydroxy-3-oxopropyl)-1H-indole-2-carboxylic acid, Fructose-1,6-bisphosphatase 1 著者 Wang, X.Y, Zhou, J, Xu, B.L. 登録日 2021-06-01 公開日 2022-06-01 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.76 Å) 主引用文献 Discovery of Novel Indole Derivatives as Fructose-1,6-bisphosphatase Inhibitors and X-ray Cocrystal Structures Analysis. Acs Med.Chem.Lett., 13, 2022
7P72	The PDZ domain of SNX27 complexed with the PDZ-binding motif of MERS-E 分子名称: CALCIUM ION, Envelope small membrane protein, GLYCEROL, ... 著者 Gogl, G, Cousido-Siah, A, Trave, G. 登録日 2021-07-19 公開日 2022-07-27 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Quantitative fragmentomics allow affinity mapping of interactomes. Nat Commun, 13, 2022
7P73	The PDZ domain of SYNJ2BP complexed with the PDZ-binding motif of HTLV1-TAX1 分子名称: CALCIUM ION, GLYCEROL, Protein Tax-1, ... 著者 Gogl, G, Cousido-Siah, A, Trave, G. 登録日 2021-07-19 公開日 2022-07-27 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Quantitative fragmentomics allow affinity mapping of interactomes. Nat Commun, 13, 2022
7P74	The PDZ domain of SYNJ2BP complexed with the phosphorylated PDZ-binding motif of RSK1 分子名称: CALCIUM ION, GLYCEROL, Ribosomal protein S6 kinase alpha-1, ... 著者 Gogl, G, Cousido-Siah, A, Trave, G. 登録日 2021-07-19 公開日 2022-07-27 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Quantitative fragmentomics allow affinity mapping of interactomes. Nat Commun, 13, 2022
7P70	The PDZ-domain of SNTB1 complexed with the PDZ-binding motif of HPV35-E6 分子名称: Beta-1-syntrophin,Annexin A2, CALCIUM ION, GLYCEROL, ... 著者 Gogl, G, Cousido-Siah, A, Trave, G. 登録日 2021-07-19 公開日 2022-07-27 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Quantitative fragmentomics allow affinity mapping of interactomes. Nat Commun, 13, 2022
7P71	The PDZ domain of MAGI1_2 complexed with the PDZ-binding motif of HPV35-E6 分子名称: CALCIUM ION, CITRIC ACID, GLYCEROL, ... 著者 Gogl, G, Cousido-Siah, A, Trave, G. 登録日 2021-07-19 公開日 2022-07-27 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Quantitative fragmentomics allow affinity mapping of interactomes. Nat Commun, 13, 2022
3DQV	Structural Insights into NEDD8 Activation of Cullin-RING Ligases: Conformational Control of Conjugation 分子名称: Cullin-5, NEDD8, Rbx1, ... 著者 Duda, D.M, Borg, L.A, Scott, D.C, Hunt, H.W, Hammel, M, Schulman, B.A. 登録日 2008-07-09 公開日 2008-09-30 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation. Cell(Cambridge,Mass.), 134, 2008
6P59	Crystal structure of SIVrcm Vif-CBFbeta-ELOB-ELOC complex 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Core-binding factor subunit beta, Elongin-B, ... 著者 Binning, J.M, Chesarino, N.M, Emerman, M, Gross, J.D. 登録日 2019-05-29 公開日 2019-12-25 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.942214 Å) 主引用文献 Structural Basis for a Species-Specific Determinant of an SIV Vif Protein toward Hominid APOBEC3G Antagonism. Cell Host Microbe, 26, 2019
7QQM	The PDZ domain of LRRC7 fused with ANXA2 分子名称: CALCIUM ION, GLYCEROL, Leucine-rich repeat-containing protein 7,Annexin A2 著者 Cousido-Siah, A, Trave, G, Gogl, G. 登録日 2022-01-10 公開日 2022-04-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 A scalable strategy to solve structures of PDZ domains and their complexes. Acta Crystallogr D Struct Biol, 78, 2022
7QQN	The PDZ domain of SNTG1 complexed with the acetylated PDZ-binding motif of TRPV3 分子名称: CALCIUM ION, GLYCEROL, Gamma-1-syntrophin,Annexin A2, ... 著者 Cousido-Siah, A, Trave, G, Gogl, G. 登録日 2022-01-10 公開日 2022-04-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 A scalable strategy to solve structures of PDZ domains and their complexes. Acta Crystallogr D Struct Biol, 78, 2022

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