PDB: 5515 件ウェブページステータス検索Chemie searchBIRD

---

6QXG	Crystal structure of His-tag human thymidylate synthase (HT-hTS) in complex with FdUMP 分子名称: 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, SULFATE ION, Thymidylate synthase 著者 Pozzi, C, Mangani, M. 登録日 2019-03-07 公開日 2019-04-10 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 Structural Comparison ofEnterococcus faecalisand Human Thymidylate Synthase Complexes with the Substrate dUMP and Its Analogue FdUMP Provides Hints about Enzyme Conformational Variabilities. Molecules, 24, 2019
6QXS	Crystal structure of Enteroccocus faecalis thymidylate synthase (EfTS) in complex with FdUMP 分子名称: 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid, SULFATE ION, ... 著者 Pozzi, C, Mangani, M. 登録日 2019-03-07 公開日 2019-04-10 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.88 Å) 主引用文献 Structural Comparison ofEnterococcus faecalisand Human Thymidylate Synthase Complexes with the Substrate dUMP and Its Analogue FdUMP Provides Hints about Enzyme Conformational Variabilities. Molecules, 24, 2019
2LWT	NMR solution structure of PawS Derived Peptide 5 (PDP-5) 分子名称: PawS Derived Peptide 5 (PDP-5) 著者 Elliott, A.G, Mylne, J.S, Rosengren, K. 登録日 2012-08-06 公開日 2013-08-21 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Evolutionary origins of a bioactive peptide buried within Preproalbumin. Plant Cell, 26, 2014
2M0X	Solution structure of U14Ub1, an engineered ubiquitin variant with increased affinity for USP14 分子名称: engineered ubiquitin variant 著者 Phillips, A.H, Fairbrother, W.J, Corn, J.E. 登録日 2012-11-08 公開日 2013-06-26 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Conformational dynamics control ubiquitin-deubiquitinase interactions and influence in vivo signaling. Proc.Natl.Acad.Sci.USA, 110, 2013
6RAO	Cryo-EM structure of the anti-feeding prophage (AFP) baseplate, 6-fold symmetrised 分子名称: Afp1, Afp11, Afp12, ... 著者 Desfosses, A. 登録日 2019-04-06 公開日 2019-04-17 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Atomic structures of an entire contractile injection system in both the extended and contracted states. Nat Microbiol, 4, 2019
4DOI	Crystal structure of Arabidopsis thaliana chalcone isomerase At3g55120 (AtCHI) 分子名称: Chalcone--flavonone isomerase 1, NITRATE ION 著者 Noel, J.P, Louie, G.V, Bowman, M.E. 登録日 2012-02-09 公開日 2012-05-09 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Evolution of the chalcone-isomerase fold from fatty-acid binding to stereospecific catalysis. Nature, 485, 2012
4GLG	DNA dodecamer containing 5-methyl cytosine 分子名称: DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*(5CM)P*GP*CP*G)-3') 著者 Spingler, B, Renciuk, D, Vorlickova, M. 登録日 2012-08-14 公開日 2013-08-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Crystal structures of B-DNA dodecamer containing the epigenetic modifications 5-hydroxymethylcytosine or 5-methylcytosine. Nucleic Acids Res., 41, 2013
2JI5	Structure of UMP kinase from Pyrococcus furiosus complexed with UTP 分子名称: URIDINE 5'-TRIPHOSPHATE, URIDYLATE KINASE 著者 Marco-Marin, C, Rubio, V. 登録日 2007-02-26 公開日 2007-10-16 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 The Structure of Ump Kinase from Pyrococcus Furiosus Complexed with Utp To be Published
6RGL	Cryo-EM structure of the anti-feeding prophage (AFP) baseplate in contracted state 分子名称: Afp2, Afp3, Afp4 著者 Desfosses, A. 登録日 2019-04-16 公開日 2019-04-24 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (5.4 Å) 主引用文献 Atomic structures of an entire contractile injection system in both the extended and contracted states. Nat Microbiol, 4, 2019
2IDJ	Crystal Structure of Rat Glycine N-Methyltransferase Apoprotein, Monoclinic Form 分子名称: CALCIUM ION, Glycine N-methyltransferase 著者 Luka, Z, Pakhomova, S, Loukachevitch, L.V, Egli, M, Newcomer, M.E, Wagner, C. 登録日 2006-09-15 公開日 2006-12-19 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 5-methyltetrahydrofolate is bound in intersubunit areas of rat liver folate-binding protein glycine N-methyltransferase. J.Biol.Chem., 282, 2007
6RW0	Crystal structure of ANGEL2, a 2',3'-cyclic phosphatase 分子名称: GLYCEROL, MAGNESIUM ION, POTASSIUM ION, ... 著者 Kroupova, A, Jinek, M. 登録日 2019-06-03 公開日 2020-05-20 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 ANGEL2 is a member of the CCR4 family of deadenylases with 2',3'-cyclic phosphatase activity. Science, 369, 2020
6Q3F	CDK2 in complex with FragLite2 分子名称: 4-bromanylpyridin-2-amine, Cyclin-dependent kinase 2 著者 Wood, D.J, Martin, M.P, Noble, M.E.M. 登録日 2018-12-04 公開日 2019-03-20 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.18 Å) 主引用文献 FragLites-Minimal, Halogenated Fragments Displaying Pharmacophore Doublets. An Efficient Approach to Druggability Assessment and Hit Generation. J.Med.Chem., 62, 2019
4FIQ	Crystal structure of pyridoxal biosynthesis lyase PdxS from Pyrococcus horikoshii 分子名称: Pyridoxal biosynthesis lyase pdxS 著者 Matsuura, A, Yoon, J.Y, Yoon, H.J, Lee, H.H, Suh, S.W. 登録日 2012-06-11 公開日 2012-11-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure of pyridoxal biosynthesis lyase PdxS from Pyrococcus horikoshii. Mol.Cells, 34, 2012
6QF8	Solution NMR ensemble for human ubiquitin at 298K compiled using the CoMAND method 分子名称: Polyubiquitin-B 著者 ElGamacy, M, Truffault, V, Zhu, H, Coles, M. 登録日 2019-01-09 公開日 2019-04-10 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Mapping Local Conformational Landscapes of Proteins in Solution. Structure, 27, 2019
2IDK	Crystal Structure of Rat Glycine N-Methyltransferase Complexed With Folate 分子名称: 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID, Glycine N-methyltransferase 著者 Luka, Z, Pakhomova, S, Loukachevitch, L.V, Egli, M, Newcomer, M.E, Wagner, C. 登録日 2006-09-15 公開日 2006-12-19 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 5-methyltetrahydrofolate is bound in intersubunit areas of rat liver folate-binding protein glycine N-methyltransferase. J.Biol.Chem., 282, 2007
4FIR	Crystal structure of pyridoxal biosynthesis lyase PdxS from Pyrococcus 分子名称: Pyridoxal biosynthesis lyase pdxS, RIBOSE-5-PHOSPHATE 著者 Matsuura, A, Yoon, J.Y, Yoon, H.J, Lee, H.H, Suh, S.W. 登録日 2012-06-11 公開日 2012-11-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Crystal structure of pyridoxal biosynthesis lyase PdxS from Pyrococcus horikoshii. Mol.Cells, 34, 2012
6Q4D	CDK2 in complex with FragLite31 分子名称: 2-(4-bromanyl-2-methoxy-phenyl)ethanoic acid, Cyclin-dependent kinase 2 著者 Wood, D.J, Martin, M.P, Noble, M.E.M. 登録日 2018-12-05 公開日 2019-03-20 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.07 Å) 主引用文献 FragLites-Minimal, Halogenated Fragments Displaying Pharmacophore Doublets. An Efficient Approach to Druggability Assessment and Hit Generation. J.Med.Chem., 62, 2019
4GLC	DNA dodecamer containing 5-hydroxymethyl-cytosine 分子名称: DNA (5'-D(*CP*GP*(5HC)P*GP*AP*AP*TP*TP*CP*GP*CP*G)-3') 著者 Spingler, B, Renciuk, D, Vorlickova, M. 登録日 2012-08-14 公開日 2013-08-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.831 Å) 主引用文献 Crystal structures of B-DNA dodecamer containing the epigenetic modifications 5-hydroxymethylcytosine or 5-methylcytosine. Nucleic Acids Res., 41, 2013
6Q4C	CDK2 in complex with FragLite16 分子名称: 4-bromanyl-1,8-naphthyridine, Cyclin-dependent kinase 2 著者 Wood, D.J, Martin, M.P, Noble, M.E.M. 登録日 2018-12-05 公開日 2019-03-20 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 FragLites-Minimal, Halogenated Fragments Displaying Pharmacophore Doublets. An Efficient Approach to Druggability Assessment and Hit Generation. J.Med.Chem., 62, 2019
6Q4F	CDK2 in complex with FragLite32 分子名称: Cyclin-dependent kinase 2, PYRIDINE-2,6-DIAMINE 著者 Wood, D.J, Martin, M.P, Noble, M.E.M. 登録日 2018-12-05 公開日 2019-03-20 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.21 Å) 主引用文献 FragLites-Minimal, Halogenated Fragments Displaying Pharmacophore Doublets. An Efficient Approach to Druggability Assessment and Hit Generation. J.Med.Chem., 62, 2019
6Q0V	Structure of DDB1-DDA1-DCAF15 complex bound to tasisulam and RBM39 分子名称: DDB1- and CUL4-associated factor 15, DET1- and DDB1-associated protein 1, DNA damage-binding protein 1, ... 著者 Faust, T, Yoon, H, Nowak, R.P, Donovan, K.A, Li, Z, Cai, Q, Eleuteri, N.A, Zhang, T, Gray, N.S, Fischer, E.S. 登録日 2019-08-02 公開日 2019-11-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural complementarity facilitates E7820-mediated degradation of RBM39 by DCAF15. Nat.Chem.Biol., 16, 2020
6Q4A	CDK2 in complex with FragLite14 分子名称: 5-iodanylpyrimidine, CYCLIN-DEPENDENT KINASE 2 著者 Wood, D.J, Martin, M.P, Noble, M.E.M. 登録日 2018-12-05 公開日 2019-03-20 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.13 Å) 主引用文献 FragLites-Minimal, Halogenated Fragments Displaying Pharmacophore Doublets. An Efficient Approach to Druggability Assessment and Hit Generation. J.Med.Chem., 62, 2019
6Q4I	CDK2 in complex with FragLite35 分子名称: 2-[4-[(2-oxidanylidene-3~{H}-pyridin-4-yl)oxy]phenyl]ethanoic acid, Cyclin-dependent kinase 2, DIMETHYL SULFOXIDE 著者 Wood, D.J, Martin, M.P, Noble, M.E.M. 登録日 2018-12-05 公開日 2019-03-20 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.11 Å) 主引用文献 FragLites-Minimal, Halogenated Fragments Displaying Pharmacophore Doublets. An Efficient Approach to Druggability Assessment and Hit Generation. J.Med.Chem., 62, 2019
2M07	NMR structure of OmpX in DPC micelles 分子名称: Outer membrane protein X 著者 Hagn, F.X, Etzkorn, M, Raschle, T, Wagner, G, Membrane Protein Structures by Solution NMR (MPSbyNMR) 登録日 2012-10-21 公開日 2012-12-12 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Optimized phospholipid bilayer nanodiscs facilitate high-resolution structure determination of membrane proteins. J.Am.Chem.Soc., 135, 2013
4EAM	1.70A resolution structure of apo beta-glycosidase (W33G) from sulfolobus solfataricus 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-galactosidase, ... 著者 Lovell, S, Battaile, K.P, Deckert, K, Brunner, L.C, Budiardjo, S.J, Karanicolas, J. 登録日 2012-03-22 公開日 2012-06-13 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Designing allosteric control into enzymes by chemical rescue of structure. J.Am.Chem.Soc., 134, 2012

<200201202203204205206207208209210211212213214215>