4EAM

1.70A resolution structure of apo beta-glycosidase (W33G) from sulfolobus solfataricus

Summary for 4EAM

• Entry DOI: 10.2210/pdb4eam/pdb
• Related: 4EAN
• Descriptor: Beta-galactosidase, CHLORIDE ION, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (5 entities in total)
• Functional Keywords: glycoside hydrolase, chemical biology, allosteric activation, switchable enzyme, chemical rescue, hydrolase
• Biological source: Sulfolobus solfataricus P2
• Total number of polymer chains: 2
• Total formula weight: 114426.51

Authors

Lovell, S.,Battaile, K.P.,Deckert, K.,Brunner, L.C.,Budiardjo, S.J.,Karanicolas, J. (deposition date: 2012-03-22, release date: 2012-06-13, Last modification date: 2023-09-13)

• Primary citation: Deckert, K.,Budiardjo, S.J.,Brunner, L.C.,Lovell, S.,Karanicolas, J.; Designing allosteric control into enzymes by chemical rescue of structure.; J.Am.Chem.Soc., 134:10055-10060, 2012; PubMed: 22655749; DOI: 10.1021/ja301409g

Experimental method

X-RAY DIFFRACTION (1.7 Å)