PDB: 245011 件ウェブページステータス検索Chemie searchBIRD

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4O6B	Dengue Type2 Virus Non-structural protein 1 (NS1) Form 1 crystal 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Non-structural protein 1 著者 Akey, D.L, Smith, J.L. 登録日 2013-12-20 公開日 2014-02-19 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (3.0005 Å) 主引用文献 Flavivirus NS1 structures reveal surfaces for associations with membranes and the immune system. Science, 343, 2014
4O1D	Structural Basis for Resistance to Diverse Classes of NAMPT Inhibitors 分子名称: (2E)-N-{4-[1-(benzenecarbonyl)piperidin-4-yl]butyl}-3-(pyridin-3-yl)prop-2-enamide, 1,2-ETHANEDIOL, Nicotinamide phosphoribosyltransferase, ... 著者 Oh, A, Coons, M, Brillantes, B, Wang, W. 登録日 2013-12-15 公開日 2014-10-22 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.705 Å) 主引用文献 Structural Basis for Resistance to Diverse Classes of NAMPT Inhibitors. Plos One, 9, 2014
2X4R	Crystal structure of MHC CLass I HLA-A2.1 bound to Cytomegalovirus (CMV) pp65 epitope 分子名称: 65 KDA PHOSPHOPROTEIN, BETA-2-MICROGLOBULIN, GLYCEROL, ... 著者 Celie, P.H.N, Toebes, M, Rodenko, B, Ovaa, H, Perrakis, A, Schumacher, T.N.M. 登録日 2010-02-02 公開日 2010-03-02 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Uv-Induced Ligand Exchange in Mhc Class I Protein Crystals. J.Am.Chem.Soc., 131, 2009
7YGG	Crystal structure of human CD47 in complex with engineered SIRPa.D1(N80A) 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Leukocyte surface antigen CD47, ... 著者 Yu, J, Tian, W. 登録日 2022-07-11 公開日 2022-10-19 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.76 Å) 主引用文献 Crystal Structure of Human CD47 in Complex with Engineered SIRP alpha.D1(N80A). Molecules, 27, 2022
8JRD	Chalcone synthase from Glycine max (L.) Merr (soybean) complexed with naringenin and coenzyme A 分子名称: 1,2-ETHANEDIOL, COENZYME A, DI(HYDROXYETHYL)ETHER, ... 著者 Waki, T, Imaizumi, R, Nakata, S, Yanai, T, Takeshita, K, Sakai, N, Kataoka, K, Yamamoto, M, Nakayama, T, Yamashita, S. 登録日 2023-06-16 公開日 2024-06-19 最終更新日 2024-07-17 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Structural insights into catalytic promiscuity of chalcone synthase from Glycine max (L.) Merr.: Coenzyme A-induced alteration of product specificity. Biochem.Biophys.Res.Commun., 718, 2024
7SV6	Crystal structure of SpaA-SLH/G46A/G109A in complex with 4,6-Pyr-beta-D-ManNAc-(1->4)-beta-D-GlcNAcOMe 分子名称: Surface (S-) layer glycoprotein, methyl 2-acetamido-4-O-{2-acetamido-4,6-O-[(1S)-1-carboxyethylidene]-2-deoxy-beta-D-mannopyranosyl}-2-deoxy-beta-D-glucopyranoside 著者 Legg, M.S.G, Evans, S.V. 登録日 2021-11-18 公開日 2022-03-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 The S-layer homology domains of Paenibacillus alvei surface protein SpaA bind to cell wall polysaccharide through the terminal monosaccharide residue. J.Biol.Chem., 298, 2022
7SV3	Crystal structure of SpaA-SLH in complex with 4,6-Pyr-beta-D-ManNAc-(1->4)-beta-D-GlcNAcOMe 分子名称: Surface (S-) layer glycoprotein, methyl 2-acetamido-4-O-{2-acetamido-4,6-O-[(1S)-1-carboxyethylidene]-2-deoxy-beta-D-mannopyranosyl}-2-deoxy-beta-D-glucopyranoside 著者 Legg, M.S.G, Evans, S.V. 登録日 2021-11-18 公開日 2022-03-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The S-layer homology domains of Paenibacillus alvei surface protein SpaA bind to cell wall polysaccharide through the terminal monosaccharide residue. J.Biol.Chem., 298, 2022
6TZV	Crystal Structure of the carboxyltransferase subunit of ACC (AccD6) in complex with inhibitor Phenyl-Cyclodiaone from Mycobacterium tuberculosis 分子名称: 4'-[(6-chloro-1,3-benzothiazol-2-yl)oxy]-6-hydroxy-4,4-dimethyl-4,5-dihydro[1,1'-biphenyl]-2(3H)-one, Probable propionyl-CoA carboxylase beta chain 6 著者 Reddy, M.C.M, Zhou, N, Sacchettini, J, TB Structural Genomics Consortium (TBSGC) 登録日 2019-08-13 公開日 2020-08-19 最終更新日 2025-11-12 実験手法 X-RAY DIFFRACTION (2.388 Å) 主引用文献 Novel herbicidal derivatives that inhibit carboxyltransferase subunit of the acetyl-CoA carboxylase in Mycobacterium tuberculosis To Be Published
6U10	Crystal Structure of the metallo-beta-lactamase L1 from Stenotrophomonas maltophilia in the complex with the inhibitor captopril 分子名称: 1,2-ETHANEDIOL, FORMIC ACID, L-CAPTOPRIL, ... 著者 Kim, Y, Maltseva, N, Endres, M, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2019-08-15 公開日 2019-09-11 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal Structure of the metallo-beta-lactamase L1 from Stenotrophomonas maltophilia in the complex with the inhibitor captopril. To Be Published
6FG3	Structure of Ryanodine receptor 1 in nanodiscs in the presence of calcium, ATP and ryanodine 分子名称: CALCIUM ION, Ryanodine receptor 1, ZINC ION 著者 Willegems, K, Efremov, R.G. 登録日 2018-01-09 公開日 2018-08-08 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (7.3 Å) 主引用文献 Influence of Lipid Mimetics on Gating of Ryanodine Receptor. Structure, 26, 2018
6FKY	Crystal structure of zebrafish Sirtuin 5 in complex with 3-(benzylthio)succinyl-CPS1 peptide 分子名称: (2~{R})-2-(phenylmethylsulfanyl)butanedioic acid, (2~{S})-2-(phenylmethylsulfanyl)butanedioic acid, 1,2-ETHANEDIOL, ... 著者 Pannek, M, Steegborn, C. 登録日 2018-01-25 公開日 2018-03-21 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.98 Å) 主引用文献 Potent and Selective Inhibitors of Human Sirtuin 5. J. Med. Chem., 61, 2018
9H8C	Human CDK8/Cyclin-C complex with inhibitor 2-9 分子名称: 1,2-ETHANEDIOL, 4-[(3~{S})-3-[2-[(3~{R})-3-fluoranylpyrrolidin-1-yl]pyrimidin-4-yl]piperidin-1-yl]carbonyl-1~{H}-pyrrole-2-carbonitrile, Cyclin-C, ... 著者 Somers, D.O. 登録日 2024-10-29 公開日 2025-01-22 最終更新日 2025-02-05 実験手法 X-RAY DIFFRACTION (2.573 Å) 主引用文献 Phenotype-Led Identification of IL-10 Upregulators in Human CD4 + T-cells and Elucidation of Their Pharmacology as Highly Selective CDK8/CDK19 Inhibitors. J.Med.Chem., 68, 2025
8YBC	Crystal structure of coiled coil domain of Golm1 (Golgi membrane protein 1) 分子名称: Golgi membrane protein 1 著者 Xie, X, Bai, W.F, Shi, N. 登録日 2024-02-12 公開日 2025-02-12 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 The first structure of human Golm1 coiled coil domain reveals an unexpected tetramer and highlights its structural diversity. Int.J.Biol.Macromol., 275, 2024
6GFQ	cyanobacterial GAPDH with NAD and CP12 bound 分子名称: CP12 polypeptide, Glyceraldehyde-3-phosphate dehydrogenase, MAGNESIUM ION, ... 著者 McFarlane, C.R, Murray, J.W. 登録日 2018-05-01 公開日 2019-05-08 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structural basis of light-induced redox regulation in the Calvin-Benson cycle in cyanobacteria. Proc.Natl.Acad.Sci.USA, 116, 2019
6BXA	Crystal structure of N-terminal fragment of Zebrafish Toll-Like Receptor 5 (TLR5) with Lamprey Variable Lymphocyte Receptor 2 (VLR2) bound 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Gunn, R.J, Wilson, I.A, Cooper, M.D, Herrin, B.R. 登録日 2017-12-18 公開日 2018-05-09 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.298 Å) 主引用文献 VLR Recognition of TLR5 Expands the Molecular Characterization of Protein Antigen Binding by Non-Ig-based Antibodies. J. Mol. Biol., 430, 2018
9H8S	Human CDK8/Cyclin-C complex with inhibitor 3-7 分子名称: 1,2-ETHANEDIOL, 4-[(3~{S},5~{R})-3-[2-[(3~{R})-3-fluoranylpyrrolidin-1-yl]pyrimidin-4-yl]-5-methoxy-piperidin-1-yl]carbonyl-1~{H}-pyrrole-2-carbonitrile, CHLORIDE ION, ... 著者 Somers, D.O. 登録日 2024-10-29 公開日 2025-01-22 最終更新日 2025-02-05 実験手法 X-RAY DIFFRACTION (2.157 Å) 主引用文献 Phenotype-Led Identification of IL-10 Upregulators in Human CD4 + T-cells and Elucidation of Their Pharmacology as Highly Selective CDK8/CDK19 Inhibitors. J.Med.Chem., 68, 2025
7Y5Y	X-ray Structure of Stay-Green (SGR) from Anaerolineae bacterium. 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PHOSPHATE ION, ... 著者 Dey, D, Nishijima, M, Kurisu, G, Tanaka, H, Ito, H. 登録日 2022-06-18 公開日 2022-10-19 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal structure and reaction mechanism of a bacterial Mg-dechelatase homolog from the Chloroflexi Anaerolineae. Protein Sci., 31, 2022
6GI4	Structure of Lytic Transglycosylase MltE mutant S75A from E.coli 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Endo-type membrane-bound lytic murein transglycosylase A 著者 Batuecas, M.T, Hermoso, J.A. 登録日 2018-05-09 公開日 2018-10-10 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 A Structural Dissection of the Active Site of the Lytic Transglycosylase MltE from Escherichia coli. Biochemistry, 57, 2018
8KFU	Crystal structure of ZmMOC1 in complex with a nicked Holliday junction soaked in Mn2+ for 180 seconds 分子名称: 1,2-ETHANEDIOL, DNA (25-MER), DNA (33-MER), ... 著者 Zhang, D, Luo, Z, Lin, Z. 登録日 2023-08-16 公開日 2024-06-26 最終更新日 2024-07-03 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 MOC1 cleaves Holliday junctions through a cooperative nick and counter-nick mechanism mediated by metal ions. Nat Commun, 15, 2024
5EUQ	Crystal structure of an engineered construct of phosphatidylinositol 4 kinase III beta with a potent and selective inhibitor in complex with GDP loaded Rab11 分子名称: GUANOSINE-5'-DIPHOSPHATE, Phosphatidylinositol 4-kinase beta, Ras-related protein Rab-11A, ... 著者 Burke, J.E, Fowler, M.L. 登録日 2015-11-19 公開日 2016-02-24 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Design and Structural Characterization of Potent and Selective Inhibitors of Phosphatidylinositol 4 Kinase III beta. J.Med.Chem., 59, 2016
8KFW	Crystal structure of ZmMOC1 K229A in complex with a nicked Holliday junction soaked in Mn2+ for 600 seconds 分子名称: 1,2-ETHANEDIOL, DNA (26-MER), DNA (33-MER), ... 著者 Zhang, D, Luo, Z, Lin, Z. 登録日 2023-08-16 公開日 2024-06-26 最終更新日 2024-07-03 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 MOC1 cleaves Holliday junctions through a cooperative nick and counter-nick mechanism mediated by metal ions. Nat Commun, 15, 2024
6TVB	Crystal structure of the haemagglutinin from a transmissible H10N7 seal influenza virus isolated in Netherland in complex with human receptor analogue 6'-SLN 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, ... 著者 Zhang, J, Xiong, X, Purkiss, A, Walker, P, Gamblin, S, Skehel, J.J. 登録日 2020-01-09 公開日 2020-10-21 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Hemagglutinin Traits Determine Transmission of Avian A/H10N7 Influenza Virus between Mammals. Cell Host Microbe, 28, 2020
6C18	FGFR1 kinase complex with inhibitor SN37115 分子名称: 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-{(3S)-1-[(2E)-4-(dimethylamino)but-2-enoyl]pyrrolidin-3-yl}-7-[(propan-2-yl)amino]-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-one, Fibroblast growth factor receptor 1, SULFATE ION 著者 Yosaatmadja, Y, Smaill, J.B, Squire, C.J. 登録日 2018-01-04 公開日 2019-01-16 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Understanding the structural requirements for covalent inhibition of FGFR1-3 To Be Published
7YWJ	Crystal structure of an engineered TycA variant, TycA pPLA (L313P) 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, SULFATE ION, ... 著者 Mittl, P, Camus, A, Truong, G, Markert, G, Hilvert, D. 登録日 2022-02-14 公開日 2022-09-21 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.749 Å) 主引用文献 Reprogramming Nonribosomal Peptide Synthetases for Site-Specific Insertion of alpha-Hydroxy Acids. J.Am.Chem.Soc., 144, 2022
6M8V	Crystal structure of UbiX-like FMN prenyltransferase MJ0101 from Methanocaldococcus jannaschii, FMN complex 分子名称: FLAVIN MONONUCLEOTIDE, Flavin prenyltransferase UbiX, GLYCEROL, ... 著者 Stogios, P.J, Skarina, T, Khusnutdinova, A, Wawrzak, Z, Yakunin, A.F, Savchenko, A. 登録日 2018-08-22 公開日 2020-02-26 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.221 Å) 主引用文献 Crystal structure of UbiX-like FMN prenyltransferase MJ0101 from Methanocaldococcus jannaschii, FMN complex To Be Published

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