PDB: 245011 件ウェブページステータス検索Chemie searchBIRD

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7ZPP	Cryo-EM structure of the MVV CSC intasome at 4.5A resolution 分子名称: Integrase, vDNA, non-transferred strand, ... 著者 Ballandras-Colas, A, Maskell, D, Pye, V.E, Locke, J, Swuec, S, Kotecha, A, Costa, A, Cherepanov, P. 登録日 2022-04-28 公開日 2022-05-11 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 A supramolecular assembly mediates lentiviral DNA integration Science, 355, 2017
7FSA	Structure of liver pyruvate kinase in complex with allosteric modulator 24 分子名称: (1M)-6-[4-(3-aminobenzene-1-sulfonyl)piperazine-1-sulfonyl][1,1'-biphenyl]-3,3',4,4'-tetrol, 1,6-di-O-phosphono-beta-D-fructofuranose, MAGNESIUM ION, ... 著者 Lulla, A, Nilsson, O, Brear, P, Nain-Perez, A, Grotli, M, Hyvonen, M. 登録日 2022-12-18 公開日 2023-04-12 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.909 Å) 主引用文献 Tuning liver pyruvate kinase activity up or down with a new class of allosteric modulators. Eur.J.Med.Chem., 250, 2023
4OYI	Human solAC Complexed with (4-Amino-furazan-3-yl)-phenyl-methanone 分子名称: (4-azanyl-1,2,5-oxadiazol-3-yl)-phenyl-methanone, Adenylate cyclase type 10, GLYCEROL 著者 Vinkovic, M. 登録日 2014-02-12 公開日 2014-04-02 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of human soluble adenylate cyclase reveals a distinct, highly flexible allosteric bicarbonate binding pocket. Chemmedchem, 9, 2014
6BG8	Shewanella frigidimarina ice-binding protein_1 DUF3494 Domain 分子名称: CHLORIDE ION, GLYCEROL, Ig domain protein, ... 著者 Vance, T.D.R, Davies, P.L. 登録日 2017-10-27 公開日 2018-03-07 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.59712946 Å) 主引用文献 An ice-binding and tandem beta-sandwich domain-containing protein in Shewanella frigidimarina is a potential new type of ice adhesin. FEBS J., 285, 2018
4OTI	Crystal Structure of PRK1 Catalytic Domain in Complex with Tofacitinib 分子名称: 3-{(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}-3-oxopropanenitrile, Serine/threonine-protein kinase N1 著者 Chamberlain, P.P, Delker, S, Pagarigan, B, Mahmoudi, A, Jackson, P, Abbassian, M, Muir, J, Raheja, N, Cathers, B. 登録日 2014-02-13 公開日 2014-08-27 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Crystal Structures of PRK1 in Complex with the Clinical Compounds Lestaurtinib and Tofacitinib Reveal Ligand Induced Conformational Changes. Plos One, 9, 2014
7ZNO	Crystal Structure of Unlinked NS2B_NS3 Protease from Zika Virus in Complex with Boronate Inhibitor MI-2270 分子名称: Serine protease NS3, Serine protease subunit NS2B, [(1R)-1-[[(2S)-6-azanyl-2-[[(2S)-6-azanyl-2-[2-[3-(4-carbamimidamido-3-oxidanylidene-pentyl)phenyl]ethanoylamino]hexanoyl]amino]hexanoyl]amino]-3-methyl-butyl]boronic acid 著者 Huber, S, Heine, A, Steinmetzer, T. 登録日 2022-04-21 公開日 2022-06-22 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Boroleucine-Derived Covalent Inhibitors of the ZIKV Protease. Chemmedchem, 18, 2023
6DA6	Crystal structure of the TtnD decarboxylase from the tautomycetin biosynthesis pathway of Streptomyces griseochromogenes, apo form at 2.6 A resolution (P212121) 分子名称: GLYCEROL, MAGNESIUM ION, UNKNOWN LIGAND, ... 著者 Han, L, Rudolf, J.D, Chang, C.-Y, Miller, M.D, Soman, J, Phillips Jr, G.N, Shen, B, Enzyme Discovery for Natural Product Biosynthesis (NatPro) 登録日 2018-05-01 公開日 2018-10-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 Biochemical and Structural Characterization of TtnD, a Prenylated FMN-Dependent Decarboxylase from the Tautomycetin Biosynthetic Pathway. ACS Chem. Biol., 13, 2018
7TXH	Human MRas Q71R in complex with human Shoc2 LRR domain M173I and human PP1Ca 分子名称: GLYCEROL, Leucine-rich repeat protein SHOC-2, MAGNESIUM ION, ... 著者 Hauseman, Z.J, Viscomi, J, Dhembi, A, Clark, K, King, D.A, Fodor, M. 登録日 2022-02-09 公開日 2022-06-22 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structure of the MRAS-SHOC2-PP1C phosphatase complex. Nature, 609, 2022
5GUS	Crystal structure of ASCH domain from Zymomonas mobilis 分子名称: 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, CHLORIDE ION, Helix-turn-helix domain-containing protein, ... 著者 Ha, S.C, Park, S.Y, Kim, J.S. 登録日 2016-08-31 公開日 2017-08-30 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.951 Å) 主引用文献 Crystal structure of an ASCH protein from Zymomonas mobilis and its ribonuclease activity specific for single-stranded RNA. Sci Rep, 7, 2017
4YA1	Yeast 20S proteasome beta2-H116N mutant 分子名称: CHLORIDE ION, MAGNESIUM ION, Probable proteasome subunit alpha type-7, ... 著者 Huber, E.M, Groll, M. 登録日 2015-02-17 公開日 2015-06-17 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors. J.Am.Chem.Soc., 137, 2015
4OBX	Crystal structure of yeast Coq5 in the apo form 分子名称: 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial, TRIS(HYDROXYETHYL)AMINOMETHANE 著者 Dai, Y.N, Zhou, K, Cao, D.D, Jiang, Y.L, Meng, F, Chi, C.B, Ren, Y.M, Chen, Y.X, Zhou, C.Z. 登録日 2014-01-07 公開日 2014-08-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structures and catalytic mechanism of the C-methyltransferase Coq5 provide insights into a key step of the yeast coenzyme Q synthesis pathway. Acta Crystallogr.,Sect.D, 70, 2014
8SWY	PARP4 ART domain bound to NADH 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, GLYCEROL, Protein mono-ADP-ribosyltransferase PARP4 著者 Frigon, L, Pascal, J.M. 登録日 2023-05-19 公開日 2023-11-08 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structural and biochemical analysis of the PARP1-homology region of PARP4/vault PARP. Nucleic Acids Res., 51, 2023
8YGZ	The Crystal Structure of TGF beta R2 kinase domain from Biortus. 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, TGF-beta receptor type-2 著者 Wang, F, Cheng, W, Lv, Z, Ju, C, Wang, J. 登録日 2024-02-27 公開日 2024-03-13 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The Crystal Structure of TGF beta R2 kinase domain from Biortus. To Be Published
6KWH	Crystal Structure Analysis of Endo-beta-1,4-xylanase II Complexed with Xylotriose 分子名称: Endo-1,4-beta-xylanase 2, IODIDE ION, beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose 著者 Li, C, Wan, Q. 登録日 2019-09-06 公開日 2021-07-14 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.808 Å) 主引用文献 X-ray crystallographic studies of family 11 xylanase Michaelis and product complexes: implications for the catalytic mechanism To Be Published
6BCX	mTORC1 structure refined to 3.0 angstroms 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4E-binding protein 1, MAGNESIUM ION, ... 著者 Pavletich, N.P, Yang, H. 登録日 2017-10-20 公開日 2017-12-20 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.23 Å) 主引用文献 Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40. Nature, 552, 2017
9GM5	OCCM maturation intermediate stalled with an Arginine Finger mutation in Mcm5: Conformer 1 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cell division cycle protein CDT1, ... 著者 Butryn, A, Costa, A. 登録日 2024-08-28 公開日 2025-03-05 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Unidirectional MCM translocation away from ORC drives origin licensing. Nat Commun, 16, 2025
8XPX	The Crystal Structure of PARP12 from Biortus. 分子名称: 1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Wang, F, Cheng, W, Lv, Z, Qi, J, Shen, Z. 登録日 2024-01-04 公開日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 The Crystal Structure of PARP12 from Biortus. To Be Published
8XS4	Cryo-EM structure of OSCA1.2-DOPC-1:20-contracted1 state 分子名称: Calcium permeable stress-gated cation channel 1 著者 Zhang, Y, Han, Y. 登録日 2024-01-08 公開日 2024-04-10 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3.23 Å) 主引用文献 Mechanical activation opens a lipid-lined pore in OSCA ion channels. Nature, 628, 2024
5JA9	Crystal structure of the HigB2 toxin in complex with Nb6 分子名称: 1,2-ETHANEDIOL, Nanobody 6, SULFATE ION, ... 著者 Hadzi, S, Loris, R. 登録日 2016-04-12 公開日 2017-04-05 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.849 Å) 主引用文献 Ribosome-dependent Vibrio cholerae mRNAse HigB2 is regulated by a beta-strand sliding mechanism. Nucleic Acids Res., 45, 2017
6HCE	Crystal structure of chicken riboflavin binding protein in "Apo" form at 2.5 A resolution 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... 著者 Loch, J.I, Lipowska, J, Lewinski, K. 登録日 2018-08-14 公開日 2018-08-29 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of chicken riboflavin binding protein in "Apo" form at 2.5 A resolution To Be Published
6BCU	Cryo-EM structure of the activated RHEB-mTORC1 refined to 3.4 angstrom 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4E-binding protein 1, GTP-binding protein Rheb, ... 著者 Pavletich, N.P, Yang, H. 登録日 2017-10-20 公開日 2017-12-20 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40. Nature, 552, 2017
3N6Y	Crystal structure of an immunoglobulin-like protein (PA1606) from PSEUDOMONAS AERUGINOSA at 1.50 A resolution 分子名称: SULFATE ION, TETRAETHYLENE GLYCOL, immunoglobulin-like protein 著者 Joint Center for Structural Genomics (JCSG) 登録日 2010-05-26 公開日 2010-07-21 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structure of an immunoglobulin-like protein (PA1606) from PSEUDOMONAS AERUGINOSA at 1.50 A resolution To be published
7SWH	Crystal Structure of Putative cystathionine gamma-synthase from Burkholderia pseudomallei in Complex with PLP 分子名称: 1,2-ETHANEDIOL, Putative cystathionine gamma-synthase 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2021-11-19 公開日 2021-12-01 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal Structure of Putative cystathionine gamma-synthase from Burkholderia pseudomallei in Complex with PLP to be published
6I0K	Structure of quinolinate synthase in complex with 4-mercaptophthalic acid 分子名称: 4-mercaptoidenecyclohexa-2,5-diene-1,2-dicarboxylic acid, CHLORIDE ION, IRON/SULFUR CLUSTER, ... 著者 Volbeda, A, Fontecilla-Camps, J.C. 登録日 2018-10-26 公開日 2019-03-20 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Design of specific inhibitors of quinolinate synthase based on [4Fe-4S] cluster coordination. Chem.Commun.(Camb.), 55, 2019
4Y9Y	Yeast 20S proteasome beta2-H116E mutant 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, Proteasome subunit alpha type-1, ... 著者 Huber, E.M, Groll, M. 登録日 2015-02-17 公開日 2015-06-17 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors. J.Am.Chem.Soc., 137, 2015

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