6AGN
 
 | | Structure of HEWL co-crystallised with Cinnamaldehyde | | 分子名称: | (2E)-3-phenylprop-2-enal, (2Z)-3-phenylprop-2-enal, 1,2-ETHANEDIOL, ... | | 著者 | Seyedarabi, A, Seraj, Z. | | 登録日 | 2018-08-13 | | 公開日 | 2019-08-14 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.08 Å) | | 主引用文献 | The role of Cinnamaldehyde and Phenyl ethyl alcohol as two types of precipitants affecting protein hydration levels.
Int.J.Biol.Macromol., 146, 2019
|
|
6E5A
 | | PPARg in complex with compound 4b | | 分子名称: | (5Z)-5-({4-[(prop-2-yn-1-yl)oxy]phenyl}methylidene)-2-sulfanylidene-1,3-thiazolidin-4-one, Peroxisome proliferator-activated receptor gamma | | 著者 | Bruning, J.B, Chua, B.S.K. | | 登録日 | 2018-07-19 | | 公開日 | 2019-03-13 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Shooting three inflammatory targets with a single bullet: Novel multi-targeting anti-inflammatory glitazones.
Eur J Med Chem, 167, 2019
|
|
6E63
 | | Crystal structure of malaria transmission-blocking antigen Pfs48/45 6C in complex with antibody TB31F | | 分子名称: | GLYCEROL, Pf48/45, TB31F Fab heavy chain, ... | | 著者 | Kundu, P, Semesi, A, Julien, J.P. | | 登録日 | 2018-07-23 | | 公開日 | 2018-11-28 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural delineation of potent transmission-blocking epitope I on malaria antigen Pfs48/45.
Nat Commun, 9, 2018
|
|
6RIV
 | | Crystal structure of Alopecurus myosuroides GSTF | | 分子名称: | GLYCEROL, Glutathione transferase, S-Hydroxy-Glutathione, ... | | 著者 | Papageorgiou, A.C, Poudel, N. | | 登録日 | 2019-04-25 | | 公開日 | 2020-03-04 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.33 Å) | | 主引用文献 | Comparative structural and functional analysis of phi class glutathione transferases involved in multiple-herbicide resistance of grass weeds and crops.
Plant Physiol Biochem., 149, 2020
|
|
6RTA
 | |
5ILB
 | | Crystal structure of protease domain of Deg2 linked with the PDZ domain of Deg9 | | 分子名称: | Protease Do-like 2, chloroplastic,Protease Do-like 9 | | 著者 | Ouyang, M, Liu, L, Li, X.Y, Zhao, S, Zhang, L.X. | | 登録日 | 2016-03-04 | | 公開日 | 2017-03-08 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.852 Å) | | 主引用文献 | The crystal structure of Deg9 reveals a novel octameric-type HtrA protease
Nat Plants, 3, 2017
|
|
6RT9
 | |
6EE7
 | | Small tetraheme cytochrome c from Shewanella oneidensis | | 分子名称: | HEME C, Periplasmic tetraheme cytochrome c CctA, ZINC ION | | 著者 | Huang, J, Zarzycki, J, Ducat, D.C, Kramer, D.M. | | 登録日 | 2018-08-13 | | 公開日 | 2019-08-14 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.394 Å) | | 主引用文献 | Mesoscopic to Macroscopic Electron Transfer by Hopping in a Crystal Network of Cytochromes.
J.Am.Chem.Soc., 142, 2020
|
|
6EJ2
 | | BACE1 compound 28 | | 分子名称: | Beta-secretase 1, compound 28 | | 著者 | Johansson, P. | | 登録日 | 2017-09-20 | | 公開日 | 2018-04-18 | | 最終更新日 | 2018-05-09 | | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | | 主引用文献 | Toward beta-Secretase-1 Inhibitors with Improved Isoform Selectivity.
J. Med. Chem., 61, 2018
|
|
6S1S
 | | Crystal structure of AmpC from Pseudomonas aeruginosa in complex with [3-(2-carboxyvinyl)phenyl]boronic acid] inhibitor | | 分子名称: | (~{E})-3-[3-(dihydroxyboranyl)phenyl]prop-2-enoic acid, Beta-lactamase, PHOSPHATE ION | | 著者 | Kekez, I, Vicario, M, Bellio, P, Tosoni, E, Celenza, G, Blazquez, J, Tondi, D, Cendron, L. | | 登録日 | 2019-06-19 | | 公開日 | 2019-10-09 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Phenylboronic Acids Probing Molecular Recognition against Class A and Class C beta-lactamases.
Antibiotics, 8, 2019
|
|
6E64
 | |
4HU1
 | | Crystal structure of human carbonic anhydrase isozyme XIII with the inhibitor. | | 分子名称: | 1,2-ETHANEDIOL, 2,3,5,6-tetrafluoro-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide, Carbonic anhydrase 13, ... | | 著者 | Smirnov, A, Manakova, E, Grazulis, S. | | 登録日 | 2012-11-02 | | 公開日 | 2013-04-10 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | 4-Substituted-2,3,5,6-tetrafluorobenzenesulfonamides as inhibitors of carbonic anhydrases I, II, VII, XII, and XIII.
Bioorg.Med.Chem., 21, 2013
|
|
6RRO
 | |
5IF6
 | |
6RRL
 | |
6EJ3
 | | BACE1 compound 23 | | 分子名称: | (1r,4r)-4-methoxy-6'-(5-methyl-3-pyridinyl)-3'H-dispiro[cyclohexane-1,2'-indene-1',4''-[1,3]oxazol]-2''-amine, Beta-secretase 1 | | 著者 | Johansson, P. | | 登録日 | 2017-09-20 | | 公開日 | 2018-04-18 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Toward beta-Secretase-1 Inhibitors with Improved Isoform Selectivity.
J. Med. Chem., 61, 2018
|
|
6RSM
 | | Solution NMR structure of the peptide 12530 from medicinal leech Hirudo medicinalis in dodecylphosphocholine micelles | | 分子名称: | peptide 12530 | | 著者 | Talyzina, I.A, Nadezhdin, K.D, Grafskaia, E.N, Arseniev, A.S, Lazarev, V.N. | | 登録日 | 2019-05-21 | | 公開日 | 2019-07-24 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Medicinal leech antimicrobial peptides lacking toxicity represent a promising alternative strategy to combat antibiotic-resistant pathogens.
Eur.J.Med.Chem., 180, 2019
|
|
6SDT
 | |
4HT0
 | | Crystal structure of human carbonic anhydrase isozyme II with the inhibitor. | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-[(4,6-dimethylpyrimidin-2-yl)thio]-2,3,5,6-tetrafluorobenzenesulfonamide, Carbonic anhydrase 2, ... | | 著者 | Smirnov, A, Manakova, E, Grazulis, S. | | 登録日 | 2012-10-31 | | 公開日 | 2013-04-10 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | 4-Substituted-2,3,5,6-tetrafluorobenzenesulfonamides as inhibitors of carbonic anhydrases I, II, VII, XII, and XIII.
Bioorg.Med.Chem., 21, 2013
|
|
4HT2
 | | Crystal structure of human carbonic anhydrase isozyme XII with the inhibitor. | | 分子名称: | 1,2-ETHANEDIOL, 4-[(4,6-dimethylpyrimidin-2-yl)thio]-2,3,5,6-tetrafluorobenzenesulfonamide, Carbonic anhydrase 12, ... | | 著者 | Smirnov, A, Manakova, E, Grazulis, S. | | 登録日 | 2012-10-31 | | 公開日 | 2013-04-10 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | 4-Substituted-2,3,5,6-tetrafluorobenzenesulfonamides as inhibitors of carbonic anhydrases I, II, VII, XII, and XIII.
Bioorg.Med.Chem., 21, 2013
|
|
5IFK
 | | Purine nucleoside phosphorylase | | 分子名称: | HYPOXANTHINE, Purine nucleoside phosphorylase | | 著者 | Thakur, K.G, Priyanka, A. | | 登録日 | 2016-02-26 | | 公開日 | 2017-03-01 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.967 Å) | | 主引用文献 | Functional and Structural Characterization of Purine Nucleoside Phosphorylase from Kluyveromyces lactis and Its Potential Applications in Reducing Purine Content in Food
PLoS ONE, 11, 2016
|
|
6SDG
 | |
5IL9
 | | Crystal structure of Deg9 | | 分子名称: | GLYCEROL, Protease Do-like 9 | | 著者 | Ouyang, M, Liu, L, Li, X.Y, Zhao, S, Zhang, L.X. | | 登録日 | 2016-03-04 | | 公開日 | 2017-03-08 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The crystal structure of Deg9 reveals a novel octameric-type HtrA protease
Nat Plants, 3, 2017
|
|
4I7J
 | | T4 Lysozyme L99A/M102H with benzene bound | | 分子名称: | 2-HYDROXYETHYL DISULFIDE, ACETATE ION, BENZENE, ... | | 著者 | Merski, M, Shoichet, B.K. | | 登録日 | 2012-11-30 | | 公開日 | 2013-03-27 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | | 主引用文献 | The impact of introducing a histidine into an apolar cavity site on docking and ligand recognition.
J.Med.Chem., 56, 2013
|
|
6EKS
 | | Vibrio cholerae neuraminidase complexed with oseltamivir carboxylate | | 分子名称: | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, CALCIUM ION, GLYCEROL, ... | | 著者 | Schuetz, A, Heinemann, U. | | 登録日 | 2017-09-27 | | 公開日 | 2017-11-29 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Different Inhibitory Potencies of Oseltamivir Carboxylate, Zanamivir, and Several Tannins on Bacterial and Viral Neuraminidases as Assessed in a Cell-Free Fluorescence-Based Enzyme Inhibition Assay.
Molecules, 22, 2017
|
|
