PDB: 243911 件ウェブページステータス検索Chemie searchBIRD

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6D0I	ParT: Prs ADP-ribosylating toxin bound to cognate antitoxin ParS. L48M ParT, SeMet-substituted complex. 分子名称: GLYCEROL, ParS: COG5642 (DUF2384) antitoxin fragment, ParT: COG5654 (RES domain) toxin 著者 Piscotta, F.J, Jeffrey, P.D, Link, A.J. 登録日 2018-04-10 公開日 2019-01-09 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 ParST is a widespread toxin-antitoxin module that targets nucleotide metabolism. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6D17	Crystal structure of KPC-2 complexed with compound 3 分子名称: Carbapenem-hydrolyzing beta-lactamase KPC, GLYCEROL, [(6-oxo-2H,6H-[1,3]dioxolo[4,5-g][1]benzopyran-8-yl)methyl]phosphonic acid 著者 Pemberton, O.A, Chen, Y. 登録日 2018-04-11 公開日 2019-04-17 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Heteroaryl Phosphonates as Noncovalent Inhibitors of Both Serine- and Metallocarbapenemases. J.Med.Chem., 62, 2019
6D1R	Structure of Staphylococcus aureus RNase P protein at 2.0 angstrom 分子名称: Ribonuclease P protein component 著者 Ha, L, Colquhoun, J, Noinaj, N, Das, C, Dunman, P, Flaherty, D.P. 登録日 2018-04-12 公開日 2018-09-26 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.995 Å) 主引用文献 Crystal structure of the ribonuclease-P-protein subunit from Staphylococcus aureus. Acta Crystallogr F Struct Biol Commun, 74, 2018
6D20	Crystal structure of Tyrosine-protein kinase receptor in complex with 5-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4(3H)-one and 5-{[2,4-dichloro-5-(pyridin-2-yl)benzene-1-carbonyl]amino}-N-(2-hydroxy-2-methylpropyl)-1-phenyl-1H-pyrazole-3-carboxamide Inhibitors 分子名称: 5-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4(3H)-one, 5-{[2,4-dichloro-5-(pyridin-2-yl)benzene-1-carbonyl]amino}-N-(2-hydroxy-2-methylpropyl)-1-phenyl-1H-pyrazole-3-carboxamide, High affinity nerve growth factor receptor 著者 Greasley, S.E, Johnson, E, Kraus, M.L, Cronin, C.N. 登録日 2018-04-12 公開日 2018-05-02 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Discovery of Allosteric, Potent, Subtype Selective, and Peripherally Restricted TrkA Kinase Inhibitors. J. Med. Chem., 62, 2019
6D3H	FT_T dioxygenase with bound dichlorprop 分子名称: (2R)-2-(2,4-dichlorophenoxy)propanoic acid, 2-OXOGLUTARIC ACID, CHLORIDE ION, ... 著者 Rydel, T.J, Halls, C.E. 登録日 2018-04-16 公開日 2018-08-15 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Development of enzymes for robust aryloxyphenoxypropionate and synthetic auxin herbicide tolerance traits in maize and soybean crops. Pest Manag. Sci., 75, 2019
6CWP	X-ray crystal structure of Flavobacterium johnsoniae dimanganese(II) ribonucleotide reductase beta subunit (anaerobic) 分子名称: MANGANESE (II) ION, Ribonucleotide reductase, VAL-GLU-TYR-THR-LYS-HIS 著者 Maggiolo, A.O, Rose, H.R, Boal, A.K. 登録日 2018-03-30 公開日 2018-04-18 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Structural Basis for Superoxide Activation of Flavobacterium johnsoniae Class I Ribonucleotide Reductase and for Radical Initiation by Its Dimanganese Cofactor. Biochemistry, 57, 2018
6CUQ	Crystal structure of Macrophage migration inhibitory factor-like protein (EhMIF) from Entamoeba histolytica 分子名称: 1,2-ETHANEDIOL, Macrophage migration inhibitory factor-like protein 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2018-03-26 公開日 2018-04-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Crystal structure of Macrophage migration inhibitory factor-like protein (EhMIF) from Entamoeba histolytica to be published
6CXT	Crystal structure of FAD-dependent dehydrogenase 分子名称: 1,2-ETHANEDIOL, Alpha/beta hydrolase fold protein, Butyryl-CoA dehydrogenase, ... 著者 Agarwal, V. 登録日 2018-04-04 公開日 2019-01-16 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Insights into Thiotemplated Pyrrole Biosynthesis Gained from the Crystal Structure of Flavin-Dependent Oxidase in Complex with Carrier Protein. Biochemistry, 58, 2019
6CVO	Human Aprataxin (Aptx) bound to nicked RNA-DNA, AMP and Zn product complex 分子名称: ADENOSINE MONOPHOSPHATE, Aprataxin, BETA-MERCAPTOETHANOL, ... 著者 Schellenberg, M.J, Tumbale, P.P, Williams, R.S. 登録日 2018-03-28 公開日 2018-08-29 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Mechanism of APTX nicked DNA sensing and pleiotropic inactivation in neurodegenerative disease. EMBO J., 37, 2018
6CY4	RNA octamer containing 2'-OMe, 4'- Cbeta-OMe U. 分子名称: RNA (5'-R(*(CBV)P*GP*AP*AP*(UOB)P*UP*CP*G)-3') 著者 Harp, J.M, Egli, M. 登録日 2018-04-04 公開日 2018-08-29 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.851 Å) 主引用文献 Structural basis for the synergy of 4'- and 2'-modifications on siRNA nuclease resistance, thermal stability and RNAi activity. Nucleic Acids Res., 46, 2018
6CVZ	Crystal structure of the WD40-repeat of RFWD3 分子名称: E3 ubiquitin-protein ligase RFWD3, MAGNESIUM ION 著者 DONG, A, LOPPNAU, P, SEITOVA, A, HUTCHINSON, A, TEMPEL, W, WEI, Y, Bountra, C, Arrowsmith, C.H, Edwards, A.M, BROWN, P.J, TONG, Y, Structural Genomics Consortium (SGC) 登録日 2018-03-29 公開日 2018-06-27 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Target highlights in CASP13: Experimental target structures through the eyes of their authors. Proteins, 87, 2019
6CWC	Crystal structure of SpaA-SLH 分子名称: CHLORIDE ION, SULFATE ION, Surface (S-) layer glycoprotein 著者 Blackler, R.J, Evans, S.V. 登録日 2018-03-30 公開日 2018-08-15 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural basis of cell wall anchoring by SLH domains in Paenibacillus alvei. Nat Commun, 9, 2018
6CYP	Crystal structure analysis of the H75I mutant of Superoxide Dismutase from Trichoderma reesei 分子名称: FE (III) ION, Superoxide dismutase 著者 Mendoza Rengifo, E, Ferreira Jr, J.R.S, Garratt, R.C. 登録日 2018-04-06 公開日 2018-10-10 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure of Mn Superoxide Dismutase double mutant (G74Q+Q149G) from Trichoderma reesei To Be Published
6CZQ	A V-to-F substitution in SK2 channels causes Ca2+ hypersensitivity and improves locomotion in a C. elegans ALS model 分子名称: CALCIUM ION, Calmodulin-1, SULFATE ION, ... 著者 Nam, Y.W, Zhang, M. 登録日 2018-04-09 公開日 2018-08-01 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 A V-to-F substitution in SK2 channels causes Ca2+hypersensitivity and improves locomotion in a C. elegans ALS model. Sci Rep, 8, 2018
8IIY	Crystal structure of MBP fused GAS41 YEATS domain in complex with H3K14ac peptide 分子名称: GLYCEROL, Histone H3.1, Maltodextrin-binding protein,YEATS domain-containing protein 4, ... 著者 Kikuchi, M, Umehara, T. 登録日 2023-02-24 公開日 2023-11-01 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 GAS41 promotes H2A.Z deposition through recognition of the N terminus of histone H3 by the YEATS domain. Proc.Natl.Acad.Sci.USA, 120, 2023
6D18	Crystal structure of KPC-2 complexed with compound 6 分子名称: Carbapenem-hydrolyzing beta-lactamase KPC, GLYCEROL, [(5,7-dimethyl-2-oxo-2H-1-benzopyran-4-yl)methyl]phosphonic acid 著者 Pemberton, O.A, Chen, Y. 登録日 2018-04-11 公開日 2019-04-17 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Heteroaryl Phosphonates as Noncovalent Inhibitors of Both Serine- and Metallocarbapenemases. J.Med.Chem., 62, 2019
8IIZ	Crystal structure of MBP fused GAS41 YEATS domain in complex with H3K27ac peptide 分子名称: GLYCEROL, Histone H3.1, Maltodextrin-binding protein,YEATS domain-containing protein 4, ... 著者 Kikuchi, M, Umehara, T. 登録日 2023-02-24 公開日 2023-11-01 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 GAS41 promotes H2A.Z deposition through recognition of the N terminus of histone H3 by the YEATS domain. Proc.Natl.Acad.Sci.USA, 120, 2023
6D47	Crystal structure of a DNA polymerase III subunit beta DnaN sliding clamp from Mycobacterium marinum 分子名称: Beta sliding clamp 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2018-04-17 公開日 2018-05-02 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Crystal structure of a DNA polymerase III subunit beta DnaN sliding clamp from Mycobacterium marinum To Be Published
8IN1	beta-glucosidase protein from Aplysia kurodai 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-Glucosidase, alpha-L-fucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Sun, X.M, Ye, Y.X, Kato, K, Yu, J, Yao, M. 登録日 2023-03-08 公開日 2023-11-15 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis of EHEP-mediated offense against phlorotannin-induced defense from brown algae to protect aku BGL activity. Elife, 12, 2023
6CXS	Crystal Structure of Clostridium perfringens beta-glucuronidase bound with a novel, potent inhibitor 4-(8-(piperazin-1-yl)-1,2,3,4-tetrahydro-[1,2,3]triazino[4',5':4,5]thieno[2,3-c]isoquinolin-5-yl)morpholine 分子名称: 4-(8-(piperazin-1-yl)-1,2,3,4-tetrahydro-[1,2,3]triazino[4',5':4,5]thieno[2,3-c]isoquinolin-5-yl)morpholine, Beta-glucuronidase, Maltose/maltodextrin-binding periplasmic protein 著者 Wallace, B.D, Redinbo, M.R. 登録日 2018-04-04 公開日 2019-04-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Targeted inhibition of gut bacterial beta-glucuronidase activity enhances anticancer drug efficacy. Proc.Natl.Acad.Sci.USA, 2020
6CYO	Crystal structure of human UBE2A (RAD6A) 分子名称: Ubiquitin-conjugating enzyme E2 A 著者 Ranzani, A.T, de Oliveira, J.F. 登録日 2018-04-06 公開日 2018-12-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Mechanistic insights revealed by a UBE2A mutation linked to intellectual disability. Nat. Chem. Biol., 15, 2019
6CYS	Crystal structure analysis of the D150G mutant of Superoxide Dismutase from Trichoderma reesei 分子名称: FE (III) ION, Superoxide dismutase 著者 Mendoza Rengifo, E, Garratt, R.C, Ferreira Jr, J.R.S. 登録日 2018-04-06 公開日 2018-10-10 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal structure analysis of the D150G mutant of Superoxide Dismutase from Trichoderma reesei To Be Published
6D14	Zebrafish TRAP1 bound to AMPPNP and calcium in the asymmetric closed state 分子名称: CALCIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, TNF receptor-associated protein 1 著者 Elnatan, D, Agard, D.A. 登録日 2018-04-11 公開日 2018-04-25 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Calcium binding to a remote site can replace magnesium as cofactor for mitochondrial Hsp90 (TRAP1) ATPase activity. J.Biol.Chem., 293, 2018
6D1Z	Crystal structure of Tyrosine-protein kinase receptor in complex with 5-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4(3H)-one Inhibitor 分子名称: 5-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4(3H)-one, 5-{[5-(6-aminopyridin-2-yl)-2-chlorobenzene-1-carbonyl]amino}-1-phenyl-1H-pyrazole-3-carboxamide, GLYCEROL, ... 著者 Greasley, S.E, Johnson, E, Kraus, M.L, Cronin, C.N. 登録日 2018-04-12 公開日 2018-05-02 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Discovery of Allosteric, Potent, Subtype Selective, and Peripherally Restricted TrkA Kinase Inhibitors. J. Med. Chem., 62, 2019
1M1J	Crystal structure of native chicken fibrinogen with two different bound ligands 分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Yang, Z, Kollman, J.M, Pandi, L, Doolittle, R.F. 登録日 2002-06-19 公開日 2002-06-26 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal Structure of Native Chicken Fibrinogen at 2.7 A Resolution Biochemistry, 40, 2001

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