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1KGC
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Immune Receptor
分子名称: T-cell receptor alpha chain, T-cell receptor beta chain
著者Kjer-Nielsen, L, Clements, C.S, Brooks, A.G, Purcell, A.W, McCluskey, J, Rossjohn, J.
登録日2001-11-26
公開日2002-12-11
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The 1.5 A crystal structure of a highly selected antiviral T cell receptor provides evidence for a structural basis of immunodominance
STRUCTURE, 10, 2002
9CYL
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Structure of LAG3 loop1 deletion bound to the MHC class II molecule I-A(b)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Class-II-associated invariant chain peptide, H-2 class II histocompatibility antigen, ...
著者Ming, Q, Tran, T.H, Antfolk, D, Luca, V.C.
登録日2024-08-02
公開日2024-08-21
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (4.66 Å)
主引用文献Structural basis for mouse LAG3 interactions with the MHC class II molecule I-A b.
Nat Commun, 15, 2024
6P95
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Structure of Lassa virus glycoprotein in complex with Fab 25.6A
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Saphire, E.O, Hastie, K.M.
登録日2019-06-09
公開日2019-09-11
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Convergent Structures Illuminate Features for Germline Antibody Binding and Pan-Lassa Virus Neutralization.
Cell, 178, 2019
1KH7
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E. COLI ALKALINE PHOSPHATASE MUTANT (D153GD330N)
分子名称: MAGNESIUM ION, SULFATE ION, ZINC ION, ...
著者Le Du, M.H, Lamoure, C, Muller, B.H, Bulgakov, O.V, Lajeunesse, E.
登録日2001-11-29
公開日2002-03-27
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Artificial evolution of an enzyme active site: structural studies of three highly active mutants of Escherichia coli alkaline phosphatase.
J.Mol.Biol., 316, 2002
1KHL
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E. COLI ALKALINE PHOSPHATASE MUTANT (D153HD330N) COMPLEX WITH PHOSPHATE
分子名称: Alkaline Phosphatase, PHOSPHATE ION, ZINC ION
著者Le Du, M.H, Lamoure, C, Muller, B.H, Bulgakov, O.V, Lajeunesse, E, Menez, A, Boulain, J.C.
登録日2001-11-30
公開日2002-03-13
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Artificial evolution of an enzyme active site: structural studies of three highly active mutants of Escherichia coli alkaline phosphatase.
J.Mol.Biol., 316, 2002
1KXS
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NMR STUDY OF B-DNA CONTAINING A MODIFIED BASE PAIR: THE 2'-DEOXYADENOSINE 3-(2-HYDROXYETHYL-2'-DEOXYURIDINE)
分子名称: 5'-D(*CP*GP*TP*TP*TP*TP*AP*GP*AP*CP*TP*TP*GP*C)-3', 5'-D(*GP*CP*AP*AP*GP*TP*CP*(HEU)P*AP*AP*AP*AP*CP*G)-3'
著者Boulard, Y, Fazakerley, G.V, Sowers, L.C.
登録日2002-02-01
公開日2002-03-06
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The solution structure of an oligonucleotide duplex containing a 2'-deoxyadenosine-3-(2-hydroxyethyl)- 2'-deoxyuridine base pair determined by NMR and molecular dynamics studies.
Nucleic Acids Res., 30, 2002
1KFV
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Crystal Structure of Lactococcus lactis Formamido-pyrimidine DNA Glycosylase (alias Fpg or MutM) Non Covalently Bound to an AP Site Containing DNA.
分子名称: 5'-D(*CP*TP*CP*TP*TP*TP*(PDI)P*TP*TP*TP*CP*TP*C)-3', 5'-D(*GP*AP*GP*AP*AP*AP*CP*AP*AP*AP*GP*AP*G)-3', Formamido-pyrimidine DNA glycosylase, ...
著者Serre, L, Pereira de Jesus, K, Boiteux, S, Zelwer, C, Castaing, B.
登録日2001-11-23
公開日2002-06-14
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Crystal structure of the Lactococcus lactis formamidopyrimidine-DNA glycosylase bound to an abasic site analogue-containing DNA.
EMBO J., 21, 2002
7AB5
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Crystal structure of the Escherichia coli toxin-antitoxin system HipBST (HipT D233Q)
分子名称: Couple_hipA domain-containing protein, HipA_C domain-containing protein, Predicted transcriptional regulator, ...
著者Baerentsen, R.L, Brodersen, D.E.
登録日2020-09-06
公開日2022-01-12
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis for regulation of a tripartite toxin-antitoxin system by dual phosphorylation
Biorxiv, 2022
1KI1
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Guanine Nucleotide Exchange Region of Intersectin in Complex with Cdc42
分子名称: G25K GTP-binding protein, placental isoform, SULFATE ION, ...
著者Snyder, J.T, Pruitt, W.M, Der, C.J, Sondek, J.
登録日2001-12-02
公開日2002-05-29
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for the selective activation of Rho GTPases by Dbl exchange factors.
Nat.Struct.Biol., 9, 2002
6ZNC
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Structural basis of reactivation of oncogenic p53 mutants by a small molecule: methylene quinuclidinone (MQ). Human wild-type p53DBD bound to DNA and MQ: wt-DNA-MQ (I)
分子名称: (2~{R})-2-methyl-1-azabicyclo[2.2.2]octan-3-one, (2~{S})-2-methyl-1-azabicyclo[2.2.2]octan-3-one, Cellular tumor antigen p53, ...
著者Rozenberg, H, Degtjarik, O, Diskin-Posner, Y, Shakked, Z.
登録日2020-07-06
公開日2021-12-08
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Structural basis of reactivation of oncogenic p53 mutants by a small molecule: methylene quinuclidinone (MQ).
Nat Commun, 12, 2021
1KJV
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TAP-B-associated rat MHC class I molecule
分子名称: Mature alpha chain of major histocompatibility complex class I antigen (HEAVY CHAIN), SULFATE ION, beta-2-microglobulin, ...
著者Rudolph, M.G, Stevens, J, Speir, J.A, Trowsdale, J, Butcher, G.W, Joly, E, Wilson, I.A.
登録日2001-12-05
公開日2002-12-18
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Crystal structures of two rat MHC class Ia (RT1-A) molecules that are associated differentially with peptide transporter alleles TAP-A and TAP-B.
J.Mol.Biol., 324, 2002
1KKE
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Crystal Structure of Reovirus Attachment Protein Sigma1 Trimer
分子名称: SIGMA 1 PROTEIN
著者Chappell, J.D, Prota, A.E, Dermody, T.S, Stehle, T.
登録日2001-12-07
公開日2001-12-21
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of reovirus attachment protein sigma1 reveals evolutionary relationship to adenovirus fiber.
EMBO J., 21, 2002
1KKP
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Crystal Structure of Serine Hydroxymethyltransferase complexed with Serine
分子名称: PYRIDOXAL-5'-PHOSPHATE, SERINE, Serine Hydroxymethyltransferase
著者Trivedi, V, Gupta, A, Jala, V.R, Saravanan, P, Rao, G.S.J, Rao, N.A, Savithri, H.S, Subramanya, H.S.
登録日2001-12-10
公開日2002-07-10
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Crystal structure of binary and ternary complexes of serine hydroxymethyltransferase from Bacillus stearothermophilus: insights into the catalytic mechanism.
J.Biol.Chem., 277, 2002
7ADI
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KirBac3.1 W46R: role of a highly conserved tryptophan at the membrane-water interface of Kir channel
分子名称: Inward rectifier potassium channel Kirbac3.1, MAGNESIUM ION, POTASSIUM ION
著者Venien-Bryan, C, Fagnen, C, De Zorzi, R, Bannwarth, L, Oubella, I, Haouz, A.
登録日2020-09-15
公開日2022-01-12
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Integrative Study of the Structural and Dynamical Properties of a KirBac3.1 Mutant: Functional Implication of a Highly Conserved Tryptophan in the Transmembrane Domain.
Int J Mol Sci, 23, 2021
1KG6
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Crystal structure of the K142R mutant of E.coli MutY (core fragment)
分子名称: A/G-specific adenine glycosylase, GLYCEROL, IRON/SULFUR CLUSTER, ...
著者Gilboa, R, Kilshtein, A, Zharkov, D.O, Kycia, J.H, Gerchman, S.E, Grollman, A.P, Shoham, G.
登録日2001-11-26
公開日2002-11-26
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Analysis of the E.coli MutY DNA glycosylase structure and function by site-directed mutagenesis
To be Published
1KGN
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R2F from Corynebacterium Ammoniagenes in its oxidised, Fe containing, form
分子名称: FE (III) ION, Ribonucleotide reductase protein R2F
著者Hogbom, M, Huque, Y, Sjoberg, B.M, Nordlund, P.
登録日2001-11-28
公開日2001-12-21
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of the di-iron/radical protein of ribonucleotide reductase from Corynebacterium ammoniagenes.
Biochemistry, 41, 2002
1KHE
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PEPCK complex with nonhydrolyzable GTP analog, MAD data
分子名称: MANGANESE (II) ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, Phosphoenolpyruvate Carboxykinase, ...
著者Dunten, P, Belunis, C, Crowther, R, Hollfelder, K, Kammlott, U, Levin, W, Michel, H, Ramsey, G.B, Swain, A, Weber, D, Wertheimer, S.J.
登録日2001-11-29
公開日2002-02-27
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of human cytosolic phosphoenolpyruvate carboxykinase reveals a new GTP-binding site.
J.Mol.Biol., 316, 2002
7AB4
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Crystal structure of the Escherichia coli toxin-antitoxin system HipBST (HipT S59A)
分子名称: Couple_hipA domain-containing protein, HipA_C domain-containing protein, Predicted transcriptional regulator, ...
著者Baerentsen, R.L, Brodersen, D.E.
登録日2020-09-06
公開日2022-01-12
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (3.34 Å)
主引用文献Structural basis for regulation of a tripartite toxin-antitoxin system by dual phosphorylation
Biorxiv, 2022
7A3N
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Crystal structure of Zika virus envelope glycoprotein in complex with the Fab fragment of the broadly neutralizing human antibody EDE1 C10
分子名称: CALCIUM ION, Core protein, EDE1 C10 Fab
著者Sharma, A, Vaney, M.C, Guardado-Calvo, P, Duquerroy, S, Rouvinski, A, Rey, F.A.
登録日2020-08-18
公開日2021-12-08
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The epitope arrangement on flavivirus particles contributes to Mab C10's extraordinary neutralization breadth across Zika and dengue viruses.
Cell, 184, 2021
1KHR
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Crystal Structure of Vat(D) in Complex with Virginiamycin and Coenzyme A
分子名称: COENZYME A, STREPTOGRAMIN A ACETYLTRANSFERASE, VIRGINIAMYCIN M1
著者Sugantino, M, Roderick, S.L.
登録日2001-11-30
公開日2002-02-20
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of Vat(D): an acetyltransferase that inactivates streptogramin group A antibiotics.
Biochemistry, 41, 2002
1KL3
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an engineered streptavidin with improved affinity for the strep-tag II peptide : SAm1-StrepII
分子名称: strep-tag II peptide, streptavidin
著者Korndoerfer, I.P, Skerra, A.
登録日2001-12-11
公開日2002-04-03
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Improved affinity of engineered streptavidin for the Strep-tag II peptide is due to a fixed open conformation of the lid-like loop at the binding site.
Protein Sci., 11, 2002
1KLP
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The Solution Structure of Acyl Carrier Protein from Mycobacterium tuberculosis
分子名称: MEROMYCOLATE EXTENSION ACYL CARRIER PROTEIN
著者Wong, H.C, Liu, G, Zhang, Y.-M, Rock, C.O, Zheng, J.
登録日2001-12-12
公開日2002-06-07
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The solution structure of acyl carrier protein from Mycobacterium tuberculosis.
J.Biol.Chem., 277, 2002
7AB3
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Crystal structure of the Escherichia coli toxin-antitoxin system HipBST (HipT S57A)
分子名称: Couple_hipA domain-containing protein, HipA_C domain-containing protein, Predicted transcriptional regulator, ...
著者Baerentsen, R.L, Brodersen, D.E.
登録日2020-09-06
公開日2022-01-12
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for regulation of a tripartite toxin-antitoxin system by dual phosphorylation
Biorxiv, 2022
1KMP
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Crystal structure of the Outer Membrane Transporter FecA Complexed with Ferric Citrate
分子名称: CITRIC ACID, FE (III) ION, IRON(III) DICITRATE TRANSPORT PROTEIN FECA, ...
著者Ferguson, A.D, Chakraborty, R, Smith, B.S, Esser, L, van der Helm, D, Deisenhofer, J.
登録日2001-12-17
公開日2002-03-06
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis of gating by the outer membrane transporter FecA.
Science, 295, 2002
9CYM
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Structure of LAG3 bound to the MHC class II molecule I-A(b)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Class-II-associated invariant chain peptide, H-2 class II histocompatibility antigen, ...
著者Ming, Q, Antfolk, D, Tran, T.H, Luca, V.C.
登録日2024-08-02
公開日2024-08-21
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3.84 Å)
主引用文献Structural basis for mouse LAG3 interactions with the MHC class II molecule I-A b.
Nat Commun, 15, 2024

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