3S1B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3s1b by Molmil](/molmil-images/mine/3s1b) | |
3RXF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3rxf by Molmil](/molmil-images/mine/3rxf) | Crystal structure of Trypsin complexed with 4-aminopyridine | 分子名称: | 4-AMINOPYRIDINE, CALCIUM ION, Cationic trypsin, ... | 著者 | Yamane, J, Yao, M, Zhou, Y, Tanaka, I. | 登録日 | 2011-05-10 | 公開日 | 2011-08-24 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | In-crystal affinity ranking of fragment hit compounds reveals a relationship with their inhibitory activities J.Appl.Crystallogr., 44, 2011
|
|
3RXG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3rxg by Molmil](/molmil-images/mine/3rxg) | Crystal structure of Trypsin complexed with 4-aminocyclohexanol | 分子名称: | CALCIUM ION, Cationic trypsin, DIMETHYL SULFOXIDE, ... | 著者 | Yamane, J, Yao, M, Zhou, Y, Tanaka, I. | 登録日 | 2011-05-10 | 公開日 | 2011-08-24 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | In-crystal affinity ranking of fragment hit compounds reveals a relationship with their inhibitory activities J.Appl.Crystallogr., 44, 2011
|
|
3RXT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3rxt by Molmil](/molmil-images/mine/3rxt) | Crystal structure of Trypsin complexed with (3-methoxyphenyl)methanamin (F04 and F03, cocktail experiment) | 分子名称: | 1-(3-methoxyphenyl)methanamine, CALCIUM ION, Cationic trypsin, ... | 著者 | Yamane, J, Yao, M, Zhou, Y, Tanaka, I. | 登録日 | 2011-05-10 | 公開日 | 2011-08-24 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | In-crystal affinity ranking of fragment hit compounds reveals a relationship with their inhibitory activities J.Appl.Crystallogr., 44, 2011
|
|
3RXC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3rxc by Molmil](/molmil-images/mine/3rxc) | Crystal structure of Trypsin complexed with 2-aminopyridine | 分子名称: | 2-AMINOPYRIDINE, CALCIUM ION, Cationic trypsin, ... | 著者 | Yamane, J, Yao, M, Zhou, Y, Tanaka, I. | 登録日 | 2011-05-10 | 公開日 | 2011-08-24 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | In-crystal affinity ranking of fragment hit compounds reveals a relationship with their inhibitory activities J.Appl.Crystallogr., 44, 2011
|
|
3RXQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3rxq by Molmil](/molmil-images/mine/3rxq) | Crystal structure of Trypsin complexed with benzamide (F01 and F05, cocktail experiment) | 分子名称: | BENZAMIDINE, CALCIUM ION, Cationic trypsin, ... | 著者 | Yamane, J, Yao, M, Zhou, Y, Tanaka, I. | 登録日 | 2011-05-10 | 公開日 | 2011-08-24 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | In-crystal affinity ranking of fragment hit compounds reveals a relationship with their inhibitory activities J.Appl.Crystallogr., 44, 2011
|
|
3B21
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3b21 by Molmil](/molmil-images/mine/3b21) | |
3ATM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3atm by Molmil](/molmil-images/mine/3atm) | Crystal structure of trypsin complexed with 2-(1H-indol-3-yl)ethanamine | 分子名称: | 2-(1H-INDOL-3-YL)ETHANAMINE, CALCIUM ION, Cationic trypsin, ... | 著者 | Yamane, J, Yao, M, Tanaka, I. | 登録日 | 2011-01-05 | 公開日 | 2011-08-24 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | In-crystal affinity ranking of fragment hit compounds reveals a relationship with their inhibitory activities J.Appl.Crystallogr., 44, 2011
|
|
3ASK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ask by Molmil](/molmil-images/mine/3ask) | Structure of UHRF1 in complex with histone tail | 分子名称: | E3 ubiquitin-protein ligase UHRF1, Histone H3.3, ZINC ION | 著者 | Arita, K, Sugita, K, Unoki, M, Hamamoto, R, Sekiyama, N, Tochio, H, Ariyoshi, M, Shirakawa, M. | 登録日 | 2010-12-16 | 公開日 | 2012-01-25 | 最終更新日 | 2013-06-05 | 実験手法 | X-RAY DIFFRACTION (2.904 Å) | 主引用文献 | Recognition of modification status on a histone H3 tail by linked histone reader modules of the epigenetic regulator UHRF1 Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
3ARA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ara by Molmil](/molmil-images/mine/3ara) | Discovery of Novel Uracil Derivatives as Potent Human dUTPase Inhibitors | 分子名称: | 1-[3-({(2R)-2-[hydroxy(diphenyl)methyl]pyrrolidin-1-yl}sulfonyl)propyl]pyrimidine-2,4(1H,3H)-dione, Deoxyuridine 5'-triphosphate nucleotidohydrolase, MAGNESIUM ION | 著者 | Chong, K.T, Miyakoshi, H, Miyahara, S, Fukuoka, M. | 登録日 | 2010-11-25 | 公開日 | 2010-12-08 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Synthesis and discovery of N-carbonylpyrrolidine- or N-sulfonylpyrrolidine-containing uracil derivatives as potent human deoxyuridine triphosphatase inhibitors J.Med.Chem., 55, 2012
|
|
3APF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3apf by Molmil](/molmil-images/mine/3apf) | Crystal structure of human PI3K-gamma in complex with CH5039699 | 分子名称: | 3-[7-(1H-benzimidazol-5-yl)-2-(morpholin-4-yl)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl]phenol, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, SULFATE ION | 著者 | Nakamura, M, Fukami, T.A, Miyazaki, T, Yoshida, M. | 登録日 | 2010-10-14 | 公開日 | 2011-04-13 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.82 Å) | 主引用文献 | Discovery and biological activity of a novel class I PI3K inhibitor, CH5132799 Bioorg.Med.Chem.Lett., 21, 2011
|
|
3ASL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3asl by Molmil](/molmil-images/mine/3asl) | Structure of UHRF1 in complex with histone tail | 分子名称: | 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase UHRF1, Histone H3.3, ... | 著者 | Arita, K, Sugita, K, Unoki, M, Hamamoto, R, Sekiyama, N, Tochio, H, Ariyoshi, M, Shirakawa, M. | 登録日 | 2010-12-16 | 公開日 | 2012-01-25 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | 主引用文献 | Recognition of modification status on a histone H3 tail by linked histone reader modules of the epigenetic regulator UHRF1 Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
3ASM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3asm by Molmil](/molmil-images/mine/3asm) | |
3S1Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3s1y by Molmil](/molmil-images/mine/3s1y) | AMP-C BETA-LACTAMASE (PSEUDOMONAS AERUGINOSA) in complex with a beta-lactamase inhibitor | 分子名称: | Beta-lactamase, CHLORIDE ION, ISOPROPYL ALCOHOL, ... | 著者 | Scapin, G, Lu, J, Fitzgerald, P.M.D, Sharma, N. | 登録日 | 2011-05-16 | 公開日 | 2011-06-29 | 最終更新日 | 2013-06-26 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Side chain SAR of bicyclic Beta-lactamase inhibitors (BLIs). 2. N-Alkylated and open chain analogs of MK-8712 Bioorg.Med.Chem.Lett., 21, 2011
|
|
3ARN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3arn by Molmil](/molmil-images/mine/3arn) | Human dUTPase in complex with novel uracil derivative | 分子名称: | Deoxyuridine 5'-triphosphate nucleotidohydrolase, MAGNESIUM ION, N-{5-[(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methoxy]-2-methylpentan-2-yl}benzenesulfonamide | 著者 | Chong, K.T, Miyahara, S, Miyakoshi, H, Fukuoka, M. | 登録日 | 2010-12-03 | 公開日 | 2010-12-15 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Discovery of a novel class of potent human deoxyuridine triphosphatase inhibitors remarkably enhancing the antitumor activity of thymidylate synthase inhibitors J.Med.Chem., 55, 2012
|
|
3ATL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3atl by Molmil](/molmil-images/mine/3atl) | Crystal structure of trypsin complexed with benzamidine | 分子名称: | BENZAMIDINE, CALCIUM ION, Cationic trypsin, ... | 著者 | Yamane, J, Yao, M, Tanaka, I. | 登録日 | 2011-01-05 | 公開日 | 2011-08-24 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | In-crystal affinity ranking of fragment hit compounds reveals a relationship with their inhibitory activities J.Appl.Crystallogr., 44, 2011
|
|
3BLB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3blb by Molmil](/molmil-images/mine/3blb) | |
3BUD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3bud by Molmil](/molmil-images/mine/3bud) | |
3B1M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3b1m by Molmil](/molmil-images/mine/3b1m) | Crystal structure of the PPARgamma-LBD complexed with a cercosporamide derivative modulator Cerco-A | 分子名称: | (9aS)-8-acetyl-N-[(2-ethylnaphthalen-1-yl)methyl]-1,7-dihydroxy-3-methoxy-9a-methyl-9-oxo-9,9a-dihydrodibenzo[b,d]furan-4-carboxamide, Peroxisome proliferator-activated receptor gamma, Peroxisome proliferator-activated receptor gamma coactivator 1-alpha | 著者 | Matsui, Y, Hiroyuki, H. | 登録日 | 2011-07-05 | 公開日 | 2011-08-24 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Pharmacology and in Vitro Profiling of a Novel Peroxisome Proliferator-Activated Receptor gamma Ligand, Cerco-A Biol.Pharm.Bull., 34, 2011
|
|
3B20
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3b20 by Molmil](/molmil-images/mine/3b20) | Crystal structure of Glyceraldehyde-3-Phosphate Dehydrogenase complexed with NADfrom Synechococcus elongatus" | 分子名称: | Glyceraldehyde 3-phosphate dehydrogenase (NADP+), NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION | 著者 | Matsumura, H, Kai, A, Maeda, T, Inoue, T. | 登録日 | 2011-07-17 | 公開日 | 2012-01-11 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.398 Å) | 主引用文献 | Structure Basis for the Regulation of Glyceraldehyde-3-Phosphate Dehydrogenase Activity via the Intrinsically Disordered Protein CP12. Structure, 19, 2011
|
|
3BVX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3bvx by Molmil](/molmil-images/mine/3bvx) | |
3RXS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3rxs by Molmil](/molmil-images/mine/3rxs) | Crystal structure of Trypsin complexed with (3-methoxyphenyl)methanamine (F04 and A06, cocktail experiment) | 分子名称: | 1-(3-methoxyphenyl)methanamine, CALCIUM ION, Cationic trypsin, ... | 著者 | Yamane, J, Yao, M, Zhou, Y, Tanaka, I. | 登録日 | 2011-05-10 | 公開日 | 2011-08-24 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | In-crystal affinity ranking of fragment hit compounds reveals a relationship with their inhibitory activities J.Appl.Crystallogr., 44, 2011
|
|
3RXE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3rxe by Molmil](/molmil-images/mine/3rxe) | Crystal structure of Trypsin complexed with benzamide | 分子名称: | BENZAMIDINE, CALCIUM ION, Cationic trypsin, ... | 著者 | Yamane, J, Yao, M, Zhou, Y, Tanaka, I. | 登録日 | 2011-05-10 | 公開日 | 2011-08-24 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | In-crystal affinity ranking of fragment hit compounds reveals a relationship with their inhibitory activities J.Appl.Crystallogr., 44, 2011
|
|
3RXR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3rxr by Molmil](/molmil-images/mine/3rxr) | Crystal structure of Trypsin complexed with cycloheptanamine (F01 and F03, cocktail experiment) | 分子名称: | CALCIUM ION, Cationic trypsin, DIMETHYL SULFOXIDE, ... | 著者 | Yamane, J, Yao, M, Zhou, Y, Tanaka, I. | 登録日 | 2011-05-10 | 公開日 | 2011-08-24 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | In-crystal affinity ranking of fragment hit compounds reveals a relationship with their inhibitory activities J.Appl.Crystallogr., 44, 2011
|
|
3BVV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3bvv by Molmil](/molmil-images/mine/3bvv) | Golgi mannosidase II D204A catalytic nucleophile mutant complex with METHYL ALPHA-D-MANNOPYRANOSYL-(1->3)-[6-THIO-ALPHA-D-MANNOPYRANOSYL-(1->6)]-BETA-D-MANNOPYRANOSIDE | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, Alpha-mannosidase 2, ... | 著者 | Kuntz, D.A, Rose, D.R. | 登録日 | 2008-01-07 | 公開日 | 2008-07-01 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Probing the substrate specificity of Golgi alpha-mannosidase II by use of synthetic oligosaccharides and a catalytic nucleophile mutant. J.Am.Chem.Soc., 130, 2008
|
|