3RXR

Crystal structure of Trypsin complexed with cycloheptanamine (F01 and F03, cocktail experiment)

Summary for 3RXR

Entry DOI	10.2210/pdb3rxr/pdb
Related	3ATI 3ATK 3ATL 3ATM 3RXA 3RXB 3RXC 3RXD 3RXE 3RXF 3RXG 3RXH 3RXI 3RXJ 3RXK 3RXL 3RXM 3RXO 3RXP 3RXQ 3RXS 3RXT 3RXU 3RXV
Descriptor	Cationic trypsin, CALCIUM ION, DIMETHYL SULFOXIDE, ... (5 entities in total)
Functional Keywords	trypsin-like serine proteases, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Bos taurus (bovine)
Cellular location	Secreted, extracellular space: P00760
Total number of polymer chains	1
Total formula weight	23868.23
Authors	Yamane, J.,Yao, M.,Zhou, Y.,Tanaka, I. (deposition date: 2011-05-10, release date: 2011-08-24, Last modification date: 2024-10-30)
Primary citation	Yamane, J.,Yao, M.,Zhou, Y.,Hiramatsu, Y.,Fujiwara, K.,Yamaguchi, T.,Yamaguchi, H.,Togame, H.,Tsujishita, H.,Takemoto, H.,Tanaka, I. In-crystal affinity ranking of fragment hit compounds reveals a relationship with their inhibitory activities J.Appl.Crystallogr., 44:798-804, 2011 Cited by DOI: 10.1107/S0021889811017717 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.72 Å)

Structure validation