PDB: 4050 件ウェブページステータス検索Chemie searchBIRD

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7NPL	ALPHA-1 ANTITRYPSIN (C232S) COMPLEXED WITH cmpd 11 分子名称: Alpha-1-antitrypsin, GLYCEROL, N-((1S,2R)-1-(3-chloro-2-methylphenyl)-1-hydroxypentan-2-yl)-2-oxoindoline-4-carboxamide 著者 Chung, C. 登録日 2021-02-27 公開日 2021-04-07 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 The development of highly potent and selective small molecule correctors of Z alpha 1 -antitrypsin misfolding. Bioorg.Med.Chem.Lett., 41, 2021
7NPK	ALPHA-1 ANTITRYPSIN C232S COMPLEXED WITH CMPD3 分子名称: Alpha-1-antitrypsin, GLYCEROL, N-((1S,2R)-1-hydroxy-1-(o-tolyl)pentan-2-yl)-2-oxo-2,3-dihydrobenzo[d]oxazole-5-carboxamide 著者 Chung, C. 登録日 2021-02-27 公開日 2021-04-07 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 The development of highly potent and selective small molecule correctors of Z alpha 1 -antitrypsin misfolding. Bioorg.Med.Chem.Lett., 41, 2021
6H8M	Crystal structure of the third SRCR domain of Murine Neurotrypsin. 分子名称: Neurotrypsin 著者 Canciani, A, Forneris, F. 登録日 2018-08-02 公開日 2019-02-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural characterization of the third scavenger receptor cysteine-rich domain of murine neurotrypsin. Protein Sci., 28, 2019
1TGN	STRUCTURE OF BOVINE TRYPSINOGEN AT 1.9 ANGSTROMS RESOLUTION 分子名称: TRYPSINOGEN 著者 Kossiakoff, A.A, Stroud, R.M. 登録日 1979-09-19 公開日 1979-10-19 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structure of bovine trypsinogen at 1.9 A resolution. Biochemistry, 16, 1977
3DRU	Crystal Structure of Gly117Phe Alpha1-Antitrypsin 分子名称: Alpha-1-antitrypsin 著者 Gooptu, B, Nobeli, I, Purkiss, A, Phillips, R.L, Mallya, M, Lomas, D.A, Barrett, T.E. 登録日 2008-07-11 公開日 2009-03-31 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Crystallographic and cellular characterisation of two mechanisms stabilising the native fold of alpha1-antitrypsin: implications for disease and drug design. J.Mol.Biol., 387, 2009
4CAA	CLEAVED ANTICHYMOTRYPSIN T345R 分子名称: ANTICHYMOTRYPSIN 著者 Lukacs, C.M, Christianson, D.W. 登録日 1997-08-14 公開日 1998-02-25 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Engineering an anion-binding cavity in antichymotrypsin modulates the "spring-loaded" serpin-protease interaction. Biochemistry, 37, 1998
3T1P	Crystal structure of an alpha-1-antitrypsin trimer 分子名称: Alpha-1-antitrypsin 著者 Huntington, J.A, Yamasaki, M. 登録日 2011-07-22 公開日 2011-08-17 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.9 Å) 主引用文献 Molecular basis of alpha 1-antitrypsin deficiency revealed by the structure of a domain-swapped trimer. EMBO Rep., 12, 2011
1ATU	UNCLEAVED ALPHA-1-ANTITRYPSIN 分子名称: ALPHA-1-ANTITRYPSIN 著者 Ryu, S.-E, Choi, H.-J. 登録日 1997-05-11 公開日 1997-08-20 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The native strains in the hydrophobic core and flexible reactive loop of a serine protease inhibitor: crystal structure of an uncleaved alpha1-antitrypsin at 2.7 A. Structure, 4, 1996
5XOZ	Crystal structure of a Kunitz type trypsin inhibitor from Cicer arietinumL 分子名称: Trypsin protein inhibitor 2 著者 Bendre, A.D, Suresh, C.G, Ramasamy, S. 登録日 2017-05-31 公開日 2018-06-20 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural insights into the unique inhibitory mechanism of Kunitz type trypsin inhibitor from Cicer arietinum L. J.Biomol.Struct.Dyn., 37, 2019
4VGC	GAMMA-CHYMOTRYPSIN D-NAPHTHYL-1-ACETAMIDO BORONIC ACID INHIBITOR COMPLEX 分子名称: D-1-NAPHTHYL-2-ACETAMIDO-ETHANE BORONIC ACID, GAMMA CHYMOTRYPSIN, SULFATE ION 著者 Stoll, V.S, Eger, B.T, Hynes, R.C, Martichonok, V, Jones, J.B, Pai, E.F. 登録日 1997-05-01 公開日 1997-11-12 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes. Biochemistry, 37, 1998
1UTO	Trypsin specificity as elucidated by LIE calculations, X-ray structures and association constant measurements 分子名称: 2-PHENYLETHYLAMINE, CALCIUM ION, GLYCEROL, ... 著者 Leiros, H.-K.S, Brandsdal, B.O, Andersen, O.A, Os, V, Leiros, I, Helland, R, Otlewski, J, Willassen, N.P, Smalas, A.O. 登録日 2003-12-09 公開日 2004-01-15 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Trypsin Specificity as Elucidated by Lie Calculations, X-Ray Structures, and Association Constant Measurements Protein Sci., 13, 2004
6KV2	Crystal structure of trypsin inhibitor 1 from Senna obtusifolia 分子名称: Trypsin inhibitor 1 著者 Liao, H, Yu, Y. 登録日 2019-09-03 公開日 2020-02-19 実験手法 X-RAY DIFFRACTION (2.003 Å) 主引用文献 Structural and functional relationship of Cassia obtusifolia trypsin inhibitor to understand its digestive resistance against Pieris rapae. Int.J.Biol.Macromol., 148, 2020
2P8O	Crystal Structure of a Benzohydroxamic Acid/Vanadate complex bound to chymotrypsin A 分子名称: Chymotrypsin A chain A, Chymotrypsin A chain B, Chymotrypsin A chain C, ... 著者 Moulin, A, Bell, J.H, Pratt, R.F, Ringe, D. 登録日 2007-03-22 公開日 2007-05-08 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Inhibition of chymotrypsin by a complex of ortho-vanadate and benzohydroxamic Acid: structure of the inert complex and its mechanistic interpretation. Biochemistry, 46, 2007
7PH1	Trypsin in complex with BPTI mutant (2S)-2-amino-4-monofluorobutanoic acid 分子名称: CALCIUM ION, Cationic trypsin, GLYCEROL, ... 著者 Dimos, N, Leppkes, J, Koksch, B, Loll, B. 登録日 2021-08-16 公開日 2022-03-30 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.18 Å) 主引用文献 Water Network in the Binding Pocket of Fluorinated BPTI-Trypsin Complexes─Insights from Simulation and Experiment. J.Phys.Chem.B, 126, 2022
4U32	Human mesotrypsin complexed with HAI-2 Kunitz domain 1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Kunitz-type protease inhibitor 2, ... 著者 Wang, R, Soares, A.S, Radisky, E.S. 登録日 2014-07-18 公開日 2014-10-15 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Sequence and Conformational Specificity in Substrate Recognition: SEVERAL HUMAN KUNITZ PROTEASE INHIBITOR DOMAINS ARE SPECIFIC SUBSTRATES OF MESOTRYPSIN. J.Biol.Chem., 289, 2014
4U30	Human mesotrypsin complexed with bikunin Kunitz domain 2 分子名称: CALCIUM ION, Trypsin-3, Trypstatin 著者 Wang, R, Soares, A.S, Radisky, E.S. 登録日 2014-07-18 公開日 2014-10-15 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Sequence and Conformational Specificity in Substrate Recognition: SEVERAL HUMAN KUNITZ PROTEASE INHIBITOR DOMAINS ARE SPECIFIC SUBSTRATES OF MESOTRYPSIN. J.Biol.Chem., 289, 2014
7QIT	CRYSTAL STRUCTURE OF THE P1 trifluoroethylglycine (TfeGly) BPTI MUTANT- BOVINE CHYMOTRYPSIN COMPLEX 分子名称: Chymotrypsin A chain A, Chymotrypsin A chain B, Chymotrypsin A chain C, ... 著者 Dimos, N, Leppkes, J, Koksch, B, Wahl, M.C, Loll, B. 登録日 2021-12-15 公開日 2022-03-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Fluorine-induced polarity increases inhibitory activity of BPTI towards chymotrypsin. Rsc Chem Biol, 3, 2022
7QIQ	CRYSTAL STRUCTURE OF THE P1 aminobutanoic acid (ABU) BPTI MUTANT- BOVINE CHYMOTRYPSIN COMPLEX 分子名称: Chymotrypsin A chain A, Chymotrypsin A chain B, Chymotrypsin A chain C, ... 著者 Dimos, N, Leppkes, J, Koksch, B, Wahl, M.C, Loll, B. 登録日 2021-12-15 公開日 2022-03-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Fluorine-induced polarity increases inhibitory activity of BPTI towards chymotrypsin. Rsc Chem Biol, 3, 2022
7QIR	CRYSTAL STRUCTURE OF THE P1 monofluorethylglycine(MfeGly) BPTI MUTANT- BOVINE CHYMOTRYPSIN COMPLEX 分子名称: Chymotrypsin A chain A, Chymotrypsin A chain B, Chymotrypsin A chain C, ... 著者 Dimos, N, Leppkes, J, Koksch, B, Wahl, M.C, Loll, B. 登録日 2021-12-15 公開日 2022-03-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Fluorine-induced polarity increases inhibitory activity of BPTI towards chymotrypsin. Rsc Chem Biol, 3, 2022
7QIS	CRYSTAL STRUCTURE OF THE P1 difluoroethylglycine (DfeGly) BPTI MUTANT- BOVINE CHYMOTRYPSIN COMPLEX 分子名称: Chymotrypsin A chain A, Chymotrypsin A chain B, Chymotrypsin A chain C, ... 著者 Dimos, N, Leppkes, J, Koksch, B, Wahl, M.C, Loll, B. 登録日 2021-12-15 公開日 2022-03-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Fluorine-induced polarity increases inhibitory activity of BPTI towards chymotrypsin. Rsc Chem Biol, 3, 2022
5JYI	Trypsin bound with succinic acid at 1.9A 分子名称: CALCIUM ION, Cationic trypsin, SODIUM ION, ... 著者 Manohar, R, Kutumbarao, N.H.V, KarthiK, L, Malathy, P, Velmurugan, D, Gunasekaran, K. 登録日 2016-05-14 公開日 2016-07-06 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.914 Å) 主引用文献 Trypsin bound with succinic acid at 1.9A To Be Published
5CHA	THE REFINEMENT AND THE STRUCTURE OF THE DIMER OF ALPHA-*CHYMOTRYPSIN AT 1.67-*ANGSTROMS RESOLUTION 分子名称: ALPHA-CHYMOTRYPSIN A 著者 Blevins, R.A, Tulinsky, A. 登録日 1985-01-22 公開日 1985-04-01 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 The refinement and the structure of the dimer of alpha-chymotrypsin at 1.67-A resolution. J.Biol.Chem., 260, 1985
6YIX	Trypsin inhibitor in complex with bovine trypsin 分子名称: Cationic trypsin, DIMETHYL SULFOXIDE, SULFATE ION, ... 著者 Badran, M.J, Heine, A, Klebe, G. 登録日 2020-04-01 公開日 2020-12-02 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.31 Å) 主引用文献 Trypsin inhibitor in complex with bovine trypsin To Be Published
6YIV	Trypsin inhibitor in complex with bovine trypsin 分子名称: Cationic trypsin, DIMETHYL SULFOXIDE, SULFATE ION, ... 著者 Badran, M.J, Heine, A, Klebe, G. 登録日 2020-04-01 公開日 2020-12-02 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (0.95 Å) 主引用文献 Trypsin inhibitor in complex with bovine trypsin To Be Published
6YIW	Trypsin inhibitor in complex with bovine trypsin 分子名称: 1H-isoindol-3-amine, CALCIUM ION, Cationic trypsin, ... 著者 Badran, M.J, Heine, A, Klebe, G. 登録日 2020-04-01 公開日 2020-12-02 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (0.97 Å) 主引用文献 Trypsin inhibitor in complex with bovine trypsin To Be Published

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