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1P7B
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Crystal structure of an inward rectifier potassium channel
分子名称: POTASSIUM ION, integral membrane channel and cytosolic domains
著者Kuo, A, Gulbis, J.M, Antcliff, J.F, Rahman, T, Lowe, E.D, Zimmer, J, Cuthbertson, J, Ashcroft, F.M, Ezaki, T, Doyle, D.A.
登録日2003-05-01
公開日2003-06-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.65 Å)
主引用文献Crystal structure of the potassium channel KirBac1.1 in the closed state.
Science, 300, 2003
5YKF
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Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS (3D class1 at 4.33A)
分子名称: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, ...
著者Chen, L, Wu, J.X.
登録日2017-10-14
公開日2018-04-18
最終更新日2019-11-06
実験手法ELECTRON MICROSCOPY (4.33 Å)
主引用文献Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
5YKG
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Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS (Class2 at 4.57A)
分子名称: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, ...
著者Chen, L, Wu, J.X.
登録日2017-10-14
公開日2018-04-18
最終更新日2018-06-13
実験手法ELECTRON MICROSCOPY (4.57 Å)
主引用文献Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
5YKE
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Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS (focused refinement on TM at 4.11A)
分子名称: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11
著者Chen, L, Wu, J.X.
登録日2017-10-14
公開日2018-04-18
最終更新日2018-06-13
実験手法ELECTRON MICROSCOPY (4.11 Å)
主引用文献Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
5YW9
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Structure of pancreatic ATP-sensitive potassium channel bound with ATPgammaS (class1 5.0A)
分子名称: ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
著者Chen, L, Wu, J.X.
登録日2017-11-29
公開日2018-05-02
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (5 Å)
主引用文献Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
5YWC
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Structure of pancreatic ATP-sensitive potassium channel bound with Mg-ADP (CTD class1 at 4.3A)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, ...
著者Chen, L, Wu, J.X.
登録日2017-11-29
公開日2018-05-02
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
5YW8
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Structure of pancreatic ATP-sensitive potassium channel bound with ATPgammaS (all particles at 4.4A)
分子名称: ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
著者Chen, L, Wu, J.X.
登録日2017-11-29
公開日2018-05-02
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
5YWA
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Structure of pancreatic ATP-sensitive potassium channel bound with ATPgammaS (CTD class 2 at 6.1A)
分子名称: ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
著者Chen, L, Wu, J.X.
登録日2017-11-29
公開日2018-05-02
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (6.1 Å)
主引用文献Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
5YWB
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Structure of pancreatic ATP-sensitive potassium channel bound with Mg-ADP (CTD class2 at 5.2A)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, ...
著者Chen, L, Wu, J.X.
登録日2017-11-29
公開日2018-05-30
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (5.2 Å)
主引用文献Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.
Protein Cell, 9, 2018
5WUA
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Structure of a Pancreatic ATP-sensitive Potassium Channel
分子名称: ATP-sensitive inward rectifier potassium channel 11,superfolder GFP, SUR1
著者Li, N, Wu, J.-X, Chen, L, Gao, N.
登録日2016-12-16
公開日2017-01-25
実験手法ELECTRON MICROSCOPY (5.6 Å)
主引用文献Structure of a Pancreatic ATP-Sensitive Potassium Channel
Cell, 168, 2017
2A9H
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NMR structural studies of a potassium channel / charybdotoxin complex
分子名称: Voltage-gated potassium channel, charybdotoxin
著者Yu, L, Sun, C, Song, D, Shen, J, Xu, N, Gunasekera, A, Hajduk, P.J, Olejniczak, E.T.
登録日2005-07-11
公開日2006-01-10
最終更新日2021-10-20
実験手法SOLUTION NMR
主引用文献Nuclear magnetic resonance structural studies of a potassium channel-charybdotoxin complex.
Biochemistry, 44, 2005
3STL
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KcsA potassium channel mutant Y82C with Cadmium bound
分子名称: CADMIUM ION, POTASSIUM ION, Voltage-gated potassium channel, ...
著者Raghuraman, H, Cordero-Morales, J, Jogini, V, Perozo, E.
登録日2011-07-11
公開日2012-04-18
最終更新日2012-10-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Mechanism of Cd(2+) Coordination during Slow Inactivation in Potassium Channels.
Structure, 20, 2012
4G28
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Calcium-calmodulin complexed with the calmodulin binding domain from a small conductance potassium channel splice variant and EBIO-1
分子名称: 1-ethyl-1,3-dihydro-2H-benzimidazol-2-one, CALCIUM ION, Calmodulin, ...
著者Zhang, M, Pascal, J.M, Zhang, J.-F.
登録日2012-07-11
公開日2012-09-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Identification of the functional binding pocket for compounds targeting small-conductance Ca(2+)-activated potassium channels.
Nat Commun, 3, 2012
4G27
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Calcium-calmodulin complexed with the calmodulin binding domain from a small conductance potassium channel splice variant and phenylurea
分子名称: 1-phenylurea, CALCIUM ION, Calmodulin, ...
著者Zhang, M, Pascal, J.M, Zhang, J.-F.
登録日2012-07-11
公開日2012-09-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Identification of the functional binding pocket for compounds targeting small-conductance Ca(2+)-activated potassium channels.
Nat Commun, 3, 2012
1HO2
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NMR STRUCTURE OF THE POTASSIUM CHANNEL FRAGMENT L45 IN MICELLES
分子名称: VOLTAGE-GATED POTASSIUM CHANNEL PROTEIN
著者Ohlenschlager, O, Hojo, H, Ramachandran, R, Gorlach, M, Haris, P.I.
登録日2000-12-08
公開日2002-06-05
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Three-dimensional structure of the S4-S5 segment of the Shaker potassium channel.
Biophys.J., 82, 2002
1HO7
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NMR STRUCTURE OF THE POTASSIUM CHANNEL FRAGMENT L45 IN TFE
分子名称: VOLTAGE-GATED POTASSIUM CHANNEL PROTEIN
著者Ohlenschlager, O, Hojo, H, Ramachandran, R, Gorlach, M, Haris, P.I.
登録日2000-12-10
公開日2002-06-05
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Three-dimensional structure of the S4-S5 segment of the Shaker potassium channel.
Biophys.J., 82, 2002
1QDV
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N-TERMINAL DOMAIN, VOLTAGE-GATED POTASSIUM CHANNEL KV1.2 RESIDUES 33-131
分子名称: KV1.2 VOLTAGE-GATED POTASSIUM CHANNEL
著者Minor Jr, D.L, Lin, Y.-F, Mobley, B.C, Yu, M, Jan, Y.N, Jan, L.Y, Berger, J.M.
登録日1999-07-10
公開日2000-09-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The polar T1 interface is linked to conformational changes that open the voltage-gated potassium channel.
Cell(Cambridge,Mass.), 102, 2000
1QDW
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N-TERMINAL DOMAIN, VOLTAGE-GATED POTASSIUM CHANNEL KV1.2 RESIDUES 33-119
分子名称: KV1.2 VOLTAGE-GATED POTASSIUM CHANNEL
著者Minor Jr, D.L, Lin, Y.-F, Mobley, B.C, Avelar, A, Jan, Y.N, Jan, L.Y, Berger, J.M.
登録日1999-07-10
公開日2000-09-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The polar T1 interface is linked to conformational changes that open the voltage-gated potassium channel.
Cell(Cambridge,Mass.), 102, 2000
9CHQ
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Cryo-EM structure of the human ether-a-go-go related K+ channel (hERG) in 3 mM K+
分子名称: Potassium voltage-gated channel subfamily H member 2
著者Lau, C.H.Y, Hunter, M.J, Vandenberg, J.I.
登録日2024-07-01
公開日2024-08-21
最終更新日2024-09-11
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Potassium dependent structural changes in the selectivity filter of HERG potassium channels.
Nat Commun, 15, 2024
9CHS
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Cryo-EM structure of the human ether-a-go-go related K+ channel (hERG) in 3 mM K+ without symmetry
分子名称: Potassium voltage-gated channel subfamily H member 2
著者Lau, C.H.Y, Hunter, M.J, Vandenberg, J.I.
登録日2024-07-01
公開日2024-08-21
最終更新日2024-09-11
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Potassium dependent structural changes in the selectivity filter of HERG potassium channels.
Nat Commun, 15, 2024
9CHP
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Cryo-EM structure of the human ether-a-go-go related K+ channel (hERG) in 300 mM K+
分子名称: Potassium voltage-gated channel subfamily H member 2
著者Lau, C.H.Y, Hunter, M.J, Vandenberg, J.I.
登録日2024-07-01
公開日2024-08-21
最終更新日2024-09-11
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Potassium dependent structural changes in the selectivity filter of HERG potassium channels.
Nat Commun, 15, 2024
9CHR
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BU of 9chr by Molmil
Cryo-EM structure of the human ether-a-go-go related K+ channel (hERG) in 300 mM K+ without symmetry
分子名称: Potassium voltage-gated channel subfamily H member 2
著者Lau, C.H.Y, Hunter, M.J, Vandenberg, J.I.
登録日2024-07-01
公開日2024-08-21
最終更新日2024-09-11
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Potassium dependent structural changes in the selectivity filter of HERG potassium channels.
Nat Commun, 15, 2024
8VCH
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Voltage gated potassium ion channel Kv1.2 W366F, C-type inactivated
分子名称: POTASSIUM ION, Potassium voltage-gated channel subfamily A member 2
著者Wu, Y, Sigworth, F.J.
登録日2023-12-14
公開日2024-07-10
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.55 Å)
主引用文献Cryo-EM structures of Kv1.2 potassium channels, conducting and non-conducting.
Biorxiv, 2024
5E1A
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Structure of KcsA with L24C/R117C mutations
分子名称: POTASSIUM ION, antibody Fab fragment heavy chain, antibody Fab fragment light chain, ...
著者Upadhyay, V, Kim, D.M, Nimigean, C.M.
登録日2015-09-29
公開日2016-07-13
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Conformational heterogeneity in closed and open states of the KcsA potassium channel in lipid bicelles.
J.Gen.Physiol., 148, 2016
4RUE
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Human K2P4.1 (TRAAK) potassium channel, G124I mutant
分子名称: POTASSIUM ION, Potassium channel subfamily K member 4
著者Lolicato, M, Minor, D.L.Jr.
登録日2014-11-19
公開日2014-12-17
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Transmembrane Helix Straightening and Buckling Underlies Activation of Mechanosensitive and Thermosensitive K2P Channels.
Neuron, 84, 2014

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