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6XKT
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BU of 6xkt by Molmil
R. capsulatus cyt bc1 with both FeS proteins in c position (CIII2 c-c)
分子名称: Cytochrome b, Cytochrome c1, FE2/S2 (INORGANIC) CLUSTER, ...
著者Steimle, S, Van Eeuwen, T, Ozturk, Y, Kim, H.J, Braitbard, M, Selamoglu, N, Garcia, B.A, Schneidman-Duhovny, D, Murakami, K, Daldal, F.
登録日2020-06-27
公開日2020-12-30
最終更新日2021-03-03
実験手法ELECTRON MICROSCOPY (3.75 Å)
主引用文献Cryo-EM structures of engineered active bc 1 -cbb 3 type CIII 2 CIV super-complexes and electronic communication between the complexes.
Nat Commun, 12, 2021
6XKU
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BU of 6xku by Molmil
R. capsulatus cyt bc1 with one FeS protein in b position and one in c position (CIII2 b-c)
分子名称: Cytochrome b, Cytochrome c1, FE2/S2 (INORGANIC) CLUSTER, ...
著者Steimle, S, Van Eeuwen, T, Ozturk, Y, Kim, H.J, Braitbard, M, Selamoglu, N, Garcia, B.A, Schneidman-Duhovny, D, Murakami, K, Daldal, F.
登録日2020-06-27
公開日2020-12-30
最終更新日2021-03-03
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Cryo-EM structures of engineered active bc 1 -cbb 3 type CIII 2 CIV super-complexes and electronic communication between the complexes.
Nat Commun, 12, 2021
6XKZ
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BU of 6xkz by Molmil
R. capsulatus CIII2CIV tripartite super-complex, conformation B (SC-1B)
分子名称: COPPER (II) ION, Cbb3-type cytochrome c oxidase subunit CcoP,Cytochrome c-type cyt cy, Cytochrome b, ...
著者Steimle, S, Van Eeuwen, T, Ozturk, Y, Kim, H.J, Braitbard, M, Selamoglu, N, Garcia, B.A, Schneidman-Duhovny, D, Murakami, K, Daldal, F.
登録日2020-06-27
公開日2020-12-30
最終更新日2021-03-03
実験手法ELECTRON MICROSCOPY (7.2 Å)
主引用文献Cryo-EM structures of engineered active bc 1 -cbb 3 type CIII 2 CIV super-complexes and electronic communication between the complexes.
Nat Commun, 12, 2021
7ME6
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BU of 7me6 by Molmil
Structure of the apo form of YcnI
分子名称: MALONATE ION, Uncharacterized protein YcnI
著者Damle, M, Fisher, O.S.
登録日2021-04-06
公開日2021-08-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.053 Å)
主引用文献The YcnI protein from Bacillus subtilis contains a copper-binding domain.
J.Biol.Chem., 297, 2021
7MEK
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BU of 7mek by Molmil
Structure of copper bound to Ycnl
分子名称: COPPER (II) ION, Uncharacterized protein YcnI
著者Damle, M, Fisher, O.S.
登録日2021-04-06
公開日2021-08-18
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献The YcnI protein from Bacillus subtilis contains a copper-binding domain.
J.Biol.Chem., 297, 2021
2KOT
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BU of 2kot by Molmil
Solution structure of S100A13 with a drug amlexanox
分子名称: 2-amino-7-(1-methylethyl)-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid, Protein S100-A13
著者Rani, S.G, Mohan, S.K, Yu, C.
登録日2009-09-30
公開日2010-03-09
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Molecular level interactions of S100A13 with amlexanox: inhibitor for the formation of multi-protein complex in non-classical pathway of the acidic fibroblast growth factor
Biochemistry, 2010
4WBO
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BU of 4wbo by Molmil
Bovine G Protein Coupled Receptor Kinase 1 in Complex with Amlexanox
分子名称: 2-amino-7-(1-methylethyl)-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid, CHLORIDE ION, Rhodopsin kinase
著者Homan, K.T, Tesmer, J.J.G.
登録日2014-09-03
公開日2014-11-05
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Identification and characterization of amlexanox as a g protein-coupled receptor kinase 5 inhibitor.
Molecules, 19, 2014
3ST0
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BU of 3st0 by Molmil
Engineered medium-affinity halide-binding protein derived from YFP: halide-free
分子名称: 1,2-ETHANEDIOL, FORMIC ACID, Green fluorescent protein
著者Wang, W, Grimley, J.S, Beese, L.S, Hellinga, H.W.
登録日2011-07-08
公開日2012-07-11
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.19 Å)
主引用文献Visualization of Synaptic Inhibition with an Optogenetic Sensor Developed by Cell-Free Protein Engineering Automation.
J.Neurosci., 33, 2013
3SV5
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BU of 3sv5 by Molmil
Engineered medium-affinity halide-binding protein derived from YFP: iodide complex
分子名称: 1,2-ETHANEDIOL, FORMIC ACID, Green fluorescent protein, ...
著者Wang, W, Grimley, J.S, Beese, L.S, Hellinga, H.W.
登録日2011-07-12
公開日2012-07-18
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Visualization of Synaptic Inhibition with an Optogenetic Sensor Developed by Cell-Free Protein Engineering Automation.
J.Neurosci., 33, 2013
5W5V
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BU of 5w5v by Molmil
TBK1 co-crystal structure with amlexanox
分子名称: 2-amino-7-(1-methylethyl)-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid, Serine/threonine-protein kinase TBK1
著者Beyett, T.S, Tesmer, J.J.G.
登録日2017-06-15
公開日2018-06-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.645 Å)
主引用文献Carboxylic Acid Derivatives of Amlexanox Display Enhanced Potency toward TBK1 and IKKepsilonand Reveal Mechanisms for Selective Inhibition.
Mol. Pharmacol., 94, 2018
6BOE
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BU of 6boe by Molmil
TBK1 in complex with amide-coupled tetrazole analog of amlexanox
分子名称: 2-amino-5-oxo-7-(propan-2-yl)-N-(1H-tetrazol-5-yl)-5H-[1]benzopyrano[2,3-b]pyridine-3-carboxamide, Serine/threonine-protein kinase TBK1
著者Beyett, T.S, Tesmer, J.J.G.
登録日2017-11-19
公開日2018-09-26
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.598 Å)
主引用文献Carboxylic Acid Derivatives of Amlexanox Display Enhanced Potency toward TBK1 and IKKepsilonand Reveal Mechanisms for Selective Inhibition.
Mol. Pharmacol., 94, 2018
6BOD
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BU of 6bod by Molmil
TBK1 in complex with ethyl ester analog of amlexanox
分子名称: Serine/threonine-protein kinase TBK1, ethyl 2-amino-5-oxo-7-(propan-2-yl)-5H-[1]benzopyrano[2,3-b]pyridine-3-carboxylate
著者Beyett, T.S, Tesmer, J.J.G.
登録日2017-11-19
公開日2018-09-26
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.197 Å)
主引用文献Carboxylic Acid Derivatives of Amlexanox Display Enhanced Potency toward TBK1 and IKKepsilonand Reveal Mechanisms for Selective Inhibition.
Mol. Pharmacol., 94, 2018
6BNY
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BU of 6bny by Molmil
TBK1 in complex with tetrazole analog of amlexanox
分子名称: 2-amino-7-(propan-2-yl)-3-(1H-tetrazol-5-yl)-5H-[1]benzopyrano[2,3-b]pyridin-5-one, Serine/threonine-protein kinase TBK1
著者Beyett, T.S, Tesmer, J.J.G.
登録日2017-11-17
公開日2018-09-26
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.341 Å)
主引用文献Carboxylic Acid Derivatives of Amlexanox Display Enhanced Potency toward TBK1 and IKKepsilonand Reveal Mechanisms for Selective Inhibition.
Mol. Pharmacol., 94, 2018
6H2Y
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BU of 6h2y by Molmil
human Fab 1E6 bound to fHbp variant 3 from Neisseria meningitidis serogroup B
分子名称: 1,2-ETHANEDIOL, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, DI(HYDROXYETHYL)ETHER, ...
著者Veggi, D, Bianchi, F, Cozzi, R, Malito, E, Bottomley, M.J.
登録日2018-07-17
公開日2019-08-14
最終更新日2020-02-26
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Cocrystal structure of meningococcal factor H binding protein variant 3 reveals a new crossprotective epitope recognized by human mAb 1E6.
Faseb J., 33, 2019
6N75
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BU of 6n75 by Molmil
Crystal Structure of ATPase delta1-79 Spa47 E287A
分子名称: ATP synthase SpaL/MxiB
著者Morales, Y, Olsen, K.J, Johnson, S.J, Demler, H.J, Dickenson, N.E.
登録日2018-11-27
公開日2019-06-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.991 Å)
主引用文献Interfacial amino acids support Spa47 oligomerization and shigella type three secretion system activation.
Proteins, 87, 2019
6N6L
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BU of 6n6l by Molmil
Crystal Structure of ATPase delta 1-79 Spa47 R189A R191A mutant
分子名称: ATP synthase SpaL/MxiB, SULFATE ION
著者Morales, Y, Johnson, S.J, Demler, H.J, Dickenson, N.E.
登録日2018-11-26
公開日2019-06-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Interfacial amino acids support Spa47 oligomerization and shigella type three secretion system activation.
Proteins, 87, 2019
6N6Z
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BU of 6n6z by Molmil
Crystal Structure of ATPase delta 1-79 Spa47 R189E
分子名称: Probable ATP synthase SpaL/MxiB
著者Morales, Y, Johnson, S.J, Demler, H.J, Dickenson, N.E.
登録日2018-11-27
公開日2019-06-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.642 Å)
主引用文献Interfacial amino acids support Spa47 oligomerization and shigella type three secretion system activation.
Proteins, 87, 2019
6N71
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BU of 6n71 by Molmil
Crystal Structure of ATPase delta1-79 Spa47 R191E
分子名称: Probable ATP synthase SpaL/MxiB
著者Morales, Y, Olsen, K.J, Johnson, S.J, Demler, H.J, Dickenson, N.E.
登録日2018-11-27
公開日2019-06-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Interfacial amino acids support Spa47 oligomerization and shigella type three secretion system activation.
Proteins, 87, 2019
6N74
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BU of 6n74 by Molmil
Crystal Structure of ATPase delta1-79 Spa47 R271E
分子名称: ATP synthase SpaL/MxiB, SULFATE ION
著者Morales, Y, Johnson, S.J, Demler, H.J, Dickenson, N.E.
登録日2018-11-27
公開日2019-06-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.852 Å)
主引用文献Interfacial amino acids support Spa47 oligomerization and shigella type three secretion system activation.
Proteins, 87, 2019
6N70
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BU of 6n70 by Molmil
Crystal Structure of ATPase delta1-79 Spa47 R191A
分子名称: ATP synthase SpaL/MxiB
著者Morales, Y, Olsen, K.J, Johnson, S.J, Demler, H.J, Dickenson, N.E.
登録日2018-11-27
公開日2019-06-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.738 Å)
主引用文献Interfacial amino acids support Spa47 oligomerization and shigella type three secretion system activation.
Proteins, 87, 2019
6N6M
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BU of 6n6m by Molmil
Crystal Structure of ATPase delta1-79 Spa47 R189A
分子名称: ATP synthase SpaL/MxiB, SULFATE ION
著者Morales, Y, Johnson, S.J, Demler, H.J, Dickenson, N.E.
登録日2018-11-26
公開日2019-06-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.788 Å)
主引用文献Interfacial amino acids support Spa47 oligomerization and shigella type three secretion system activation.
Proteins, 87, 2019
6N72
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BU of 6n72 by Molmil
Crystal Structure of ATPase delta1-79 Spa47 E267R
分子名称: ATP synthase SpaL/MxiB
著者Morales, Y, Johnson, S.J, Demler, H.J, Dickenson, N.E.
登録日2018-11-27
公開日2019-06-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.735 Å)
主引用文献Interfacial amino acids support Spa47 oligomerization and shigella type three secretion system activation.
Proteins, 87, 2019
6N76
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BU of 6n76 by Molmil
Crystal Structure of ATPase delta1-79 Spa47 E287R
分子名称: ATP synthase SpaL/MxiB
著者Morales, Y, Johnson, S.J, Demler, H.J, Dickenson, N.E.
登録日2018-11-27
公開日2019-06-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.892 Å)
主引用文献Interfacial amino acids support Spa47 oligomerization and shigella type three secretion system activation.
Proteins, 87, 2019
6N73
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BU of 6n73 by Molmil
Crystal Structure of ATPase delta1-79 Spa47 R271A
分子名称: ATP synthase SpaL/MxiB
著者Morales, Y, Johnson, S.J, Demler, H.J, Dickenson, N.E.
登録日2018-11-27
公開日2019-06-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.398 Å)
主引用文献Interfacial amino acids support Spa47 oligomerization and shigella type three secretion system activation.
Proteins, 87, 2019
8PJB
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BU of 8pjb by Molmil
Cryo-EM structure of MLE in complex with UUC RNA and ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, Dosage compensation regulator, MAGNESIUM ION, ...
著者Jagtap, P.K.A, Hennig, J.
登録日2023-06-23
公開日2023-11-01
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.62 Å)
主引用文献Structural basis of RNA-induced autoregulation of the DExH-type RNA helicase maleless.
Mol.Cell, 83, 2023

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件を2024-10-16に公開中

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