PDB: 1980 件ウェブページステータス検索Chemie searchBIRD

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6OJ4	In situ structure of rotavirus VP1 RNA-dependent RNA polymerase (DLP) 分子名称: Inner capsid protein VP2, RNA-directed RNA polymerase 著者 Jenni, S, Salgado, E.N, Herrmann, T, Li, Z, Grant, T, Grigorieff, N, Trapani, S, Estrozi, L.F, Harrison, S.C. 登録日 2019-04-10 公開日 2019-04-24 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 In situ Structure of Rotavirus VP1 RNA-Dependent RNA Polymerase. J.Mol.Biol., 431, 2019
1KHW	Crystal Structure of Rabbit Hemorrhagic Disease Virus RNA-dependent RNA polymerase complexed with Mn2+ 分子名称: MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE 著者 Ng, K.K, Cherney, M.M, Vazquez, A.L, Machin, A, Alonso, J.M, Parra, F, James, M.N. 登録日 2001-12-01 公開日 2002-01-16 最終更新日 2019-07-24 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structures of active and inactive conformations of a caliciviral RNA-dependent RNA polymerase. J.Biol.Chem., 277, 2002
3CDW	Crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase (3Dpol) in complex with protein primer VPg and a pyrophosphate 分子名称: ACETATE ION, CHLORIDE ION, GLYCEROL, ... 著者 Gruez, A, Selisko, B, Roberts, M, Bricogne, G, Bussetta, C, Canard, B. 登録日 2008-02-27 公開日 2008-07-22 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase in complex with its protein primer VPg confirms the existence of a second VPg binding site on Picornaviridae polymerases J.Virol., 82, 2008
3CDU	Crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase (3Dpol) in complex with a pyrophosphate 分子名称: ACETATE ION, CHLORIDE ION, GLYCEROL, ... 著者 Gruez, A, Selisko, B, Roberts, M, Bricogne, G, Bussetta, C, Canard, B. 登録日 2008-02-27 公開日 2008-07-22 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase in complex with its protein primer VPg confirms the existence of a second VPg binding site on Picornaviridae polymerases J.Virol., 82, 2008
1KHV	Crystal Structure of Rabbit Hemorrhagic Disease Virus RNA-dependent RNA polymerase complexed with Lu3+ 分子名称: LUTETIUM (III) ION, RNA-DIRECTED RNA POLYMERASE 著者 Ng, K.K, Cherney, M.M, Vazquez, A.L, Machin, A, Alonso, J.M, Parra, F, James, M.N. 登録日 2001-12-01 公開日 2002-01-16 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structures of active and inactive conformations of a caliciviral RNA-dependent RNA polymerase. J.Biol.Chem., 277, 2002
1UVJ	The structural basis for RNA specificity and Ca2 inhibition of an RNA-dependent RNA polymerase phi6p2 with 7nt RNA 分子名称: 5'-R(*UP*UP*CP*CP)-3', MANGANESE (II) ION, RNA-directed RNA polymerase 著者 Salgado, P.S, Makeyev, E.V, Butcher, S, Bamford, D, Stuart, D.I, Grimes, J.M. 登録日 2004-01-21 公開日 2004-02-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase. Structure, 12, 2004
1UVM	The structural basis for RNA specificity and Ca2 inhibition of an RNA-dependent RNA polymerase phi6p2 with 5NT RNA conformation A 分子名称: 5'-R(*UP*UP*UP*CP*CP)-3', MANGANESE (II) ION, RNA-directed RNA polymerase 著者 Salgado, P.S, Makeyev, E.V, Butcher, S, Bamford, D, Stuart, D.I, Grimes, J.M. 登録日 2004-01-21 公開日 2004-02-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase. Structure, 12, 2004
1UVI	The structural basis for RNA specificity and Ca2 inhibition of an RNA-dependent RNA polymerase phi6p2 with 6nt RNA 分子名称: 5'-R(*UP*UP*UP*UP*CP*CP)-3', MANGANESE (II) ION, RNA-directed RNA polymerase 著者 Salgado, P.S, Makeyev, E.V, Butcher, S, Bamford, D, Stuart, D.I, Grimes, J.M. 登録日 2004-01-21 公開日 2004-02-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase. Structure, 12, 2004
2JLG	STRUCTURAL EXPLANATION FOR THE ROLE OF MN IN THE ACTIVITY OF PHI6 RNA-DEPENDENT RNA POLYMERASE 分子名称: 5'-D(*DT DT DT DC DCP)-3', GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... 著者 Poranen, M.M, Salgado, P.S, Koivunen, M.R.L, Wright, S, Bamford, D.H, Stuart, D.I, Grimes, J.M. 登録日 2008-09-09 公開日 2008-11-04 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural Explanation for the Role of Mn2+ in the Activity of {Phi}6 RNA-Dependent RNA Polymerase. Nucleic Acids Res., 36, 2008
3MMP	Structure of the Qb replicase, an RNA-dependent RNA polymerase consisting of viral and host proteins 分子名称: (2S)-1-[3-{[(2R)-2-hydroxypropyl]oxy}-2,2-bis({[(2R)-2-hydroxypropyl]oxy}methyl)propoxy]propan-2-ol, Elongation factor Tu 2, Elongation factor Ts, ... 著者 Kidmose, R.T, Vasiliev, N.N, Chetverin, A.B, Knudsen, C.R, Andersen, G.R. 登録日 2010-04-20 公開日 2010-06-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of the Qbeta replicase, an RNA-dependent RNA polymerase consisting of viral and host proteins. Proc.Natl.Acad.Sci.USA, 107, 2010
1UVN	The structural basis for RNA specificity and Ca2 inhibition of an RNA-dependent RNA polymerase phi6p2 ca2+ inhibition complex 分子名称: 5'-R(*UP*UP*UP*UP*CP*CP)-3', CALCIUM ION, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Salgado, P.S, Makeyev, E.V, Butcher, S, Bamford, D, Stuart, D.I, Grimes, J.M. 登録日 2004-01-21 公開日 2004-02-26 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase. Structure, 12, 2004
1UVL	The structural basis for RNA specificity and Ca2 inhibition of an RNA-dependent RNA polymerase phi6p2 with 5nt RNA. Conformation B 分子名称: 5'-R(*UP*UP*UP*CP*CP)-3', MANGANESE (II) ION, RNA-directed RNA polymerase 著者 Salgado, P.S, Makeyev, E.V, Butcher, S, Bamford, D, Stuart, D.I, Grimes, J.M. 登録日 2004-01-21 公開日 2004-02-26 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase. Structure, 12, 2004
1UVK	The structural basis for RNA specificity and Ca2 inhibition of an RNA-dependent RNA polymerase phi6p2 dead-end complex 分子名称: GUANOSINE-5'-MONOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Salgado, P.S, Makeyev, E.V, Butcher, S, Bamford, D, Stuart, D.I, Grimes, J.M. 登録日 2004-01-21 公開日 2004-02-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase. Structure, 12, 2004
7BTF	SARS-CoV-2 RNA-dependent RNA polymerase in complex with cofactors in reduced condition 分子名称: Non-structural protein 7, Non-structural protein 8, RNA-directed RNA polymerase, ... 著者 Gao, Y, Yan, L, Huang, Y, Liu, F, Cao, L, Wang, T, Wang, Q, Lou, Z, Rao, Z. 登録日 2020-04-01 公開日 2020-04-08 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (2.95 Å) 主引用文献 Structure of the RNA-dependent RNA polymerase from COVID-19 virus. Science, 368, 2020
6M71	SARS-Cov-2 RNA-dependent RNA polymerase in complex with cofactors 分子名称: Non-structural protein 7, Non-structural protein 8, RNA-directed RNA polymerase 著者 Gao, Y, Yan, L, Huang, Y, Liu, F, Cao, L, Wang, T, Wang, Q, Lou, Z, Rao, Z. 登録日 2020-03-16 公開日 2020-04-01 最終更新日 2021-03-10 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structure of the RNA-dependent RNA polymerase from COVID-19 virus. Science, 368, 2020
7VW5	Crystal structures of alphavirus nonstructural protein 4 (nsP4) reveal an intrinsically dynamic RNA-dependent RNA polymerase fold 分子名称: MAGNESIUM ION, RNA-directed RNA polymerase nsP4 著者 Tan, Y.B, Luo, D. 登録日 2021-11-09 公開日 2022-02-16 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structures of alphavirus nonstructural protein 4 (nsP4) reveal an intrinsically dynamic RNA-dependent RNA polymerase fold. Nucleic Acids Res., 50, 2022
7VB4	A crystal structure of alphavirus nonstructural protein 4 (nsP4) reveals an intrinsically dynamic RNA-dependent RNA polymerase 分子名称: GLYCEROL, MAGNESIUM ION, RNA-directed RNA polymerase nsP4 著者 Tan, Y.B, Luo, D. 登録日 2021-08-30 公開日 2022-02-16 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Crystal structures of alphavirus nonstructural protein 4 (nsP4) reveal an intrinsically dynamic RNA-dependent RNA polymerase fold. Nucleic Acids Res., 50, 2022
5HMZ	Dengue serotype 3 RNA-dependent RNA polymerase bound to compound 23 分子名称: 5-(5-(3-hydroxyprop-1-yn-1-yl)thiophen-2-yl)-4-methoxy-2-methyl-N-(methylsulfonyl)benzamide, RNA-directed RNA polymerase NS5, ZINC ION 著者 Noble, C.G. 登録日 2016-01-17 公開日 2016-03-30 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Discovery of Potent Non-Nucleoside Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase from a Fragment Hit Using Structure-Based Drug Design J.Med.Chem., 59, 2016
5HMX	Dengue serotype 3 RNA-dependent RNA polymerase bound to compound 10 分子名称: 2,2'-(5-(thiophen-2-yl)-1,3-phenylene)diacetic acid, RNA-directed RNA polymerase NS5, ZINC ION 著者 Noble, C.G. 登録日 2016-01-17 公開日 2016-03-30 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Discovery of Potent Non-Nucleoside Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase from a Fragment Hit Using Structure-Based Drug Design J.Med.Chem., 59, 2016
5HN0	Dengue serotype 3 RNA-dependent RNA polymerase bound to compound 4 分子名称: (6-hydroxybiphenyl-3-yl)acetic acid, RNA-directed RNA polymerase NS5, ZINC ION 著者 Noble, C.G. 登録日 2016-01-17 公開日 2016-03-30 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Discovery of Potent Non-Nucleoside Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase from a Fragment Hit Using Structure-Based Drug Design. J.Med.Chem., 59, 2016
5HMY	Dengue serotype 3 RNA-dependent RNA polymerase bound to compound 15 分子名称: 2,2'-(5-(5-(3-hydroxyprop-1-yn-1-yl)thiophen-2-yl)-1,3-phenylene)diacetic acid, RNA-directed RNA polymerase NS5, ZINC ION 著者 Noble, C.G. 登録日 2016-01-17 公開日 2016-03-30 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Discovery of Potent Non-Nucleoside Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase from a Fragment Hit Using Structure-Based Drug Design. J.Med.Chem., 59, 2016
5HMW	Dengue serotype 3 RNA-dependent RNA polymerase bound to compound 5 分子名称: 2,2'-biphenyl-3,5-diyldiacetic acid, RNA-directed RNA polymerase NS5, ZINC ION 著者 Noble, C.G. 登録日 2016-01-17 公開日 2016-03-30 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Discovery of Potent Non-Nucleoside Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase from a Fragment Hit Using Structure-Based Drug Design J.Med.Chem., 59, 2016
4B02	The C-terminal Priming Domain is Strongly Associated with the Main Body of Bacteriophage phi6 RNA-Dependent RNA Polymerase 分子名称: MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE 著者 Sarin, L.P, Wright, S, Chen, Q, Degerth, L.H, Stuart, D.I, Grimes, J.M, Bamford, D.H, Poranen, M.M. 登録日 2012-06-27 公開日 2012-08-01 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 The C-Terminal Priming Domain is Strongly Associated with the Main Body of Bacteriophage Phi6 RNA-Dependent RNA Polymerase. Virology, 432, 2012
5CX6	Crystal structure of Thosea asigna virus RNA-dependent RNA polymerase (RdRP) complexed with CDP 分子名称: CYTIDINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... 著者 Ferrero, D.S, Buxaderas, M, Rodriguez, J.F, Verdaguer, N. 登録日 2015-07-28 公開日 2015-11-11 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The Structure of the RNA-Dependent RNA Polymerase of a Permutotetravirus Suggests a Link between Primer-Dependent and Primer-Independent Polymerases. Plos Pathog., 11, 2015
5CYR	Crystal structure of Thosea asigna virus RNA-dependent RNA polymerase (RdRP) complexed with ATP and ssRNA 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... 著者 Ferrero, D.S, Buxaderas, M, Rodriguez, J.F, Verdaguer, N. 登録日 2015-07-30 公開日 2015-11-11 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.504 Å) 主引用文献 The Structure of the RNA-Dependent RNA Polymerase of a Permutotetravirus Suggests a Link between Primer-Dependent and Primer-Independent Polymerases. Plos Pathog., 11, 2015

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