7ENC
| TFIID-based PIC-Mediator holo-complex in fully-assembled state (hPIC-MED) | 分子名称: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | 著者 | Chen, X, Qi, Y, Wang, X, Wu, Z, Yin, X, Li, J, Liu, W, Xu, Y. | 登録日 | 2021-04-16 | 公開日 | 2021-05-26 | 最終更新日 | 2021-06-16 | 実験手法 | ELECTRON MICROSCOPY (4.13 Å) | 主引用文献 | Structures of the human Mediator and Mediator-bound preinitiation complex. Science, 372, 2021
|
|
7ENA
| TFIID-based PIC-Mediator holo-complex in pre-assembled state (pre-hPIC-MED) | 分子名称: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | 著者 | Chen, X, Qi, Y, Wang, X, Wu, Z, Yin, X, Li, J, Liu, W, Xu, Y. | 登録日 | 2021-04-16 | 公開日 | 2021-05-26 | 最終更新日 | 2021-06-16 | 実験手法 | ELECTRON MICROSCOPY (4.07 Å) | 主引用文献 | Structures of the human Mediator and Mediator-bound preinitiation complex. Science, 372, 2021
|
|
7EMF
| Human Mediator (deletion of MED1-IDR) in a Tail-extended conformation | 分子名称: | Isoform 2 of Mediator of RNA polymerase II transcription subunit 16, Isoform 2 of Mediator of RNA polymerase II transcription subunit 8, Mediator of RNA polymerase II transcription subunit 1, ... | 著者 | Yin, X, Li, J, Wu, Z, Liu, W, Xu, Y. | 登録日 | 2021-04-13 | 公開日 | 2021-05-05 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structures of the human Mediator and Mediator-bound preinitiation complex. Science, 372, 2021
|
|
7CNF
| |
6ZV4
| |
6ZV3
| TFIIS N-terminal domain (TND) from human MED26 | 分子名称: | Mediator of RNA polymerase II transcription subunit 26 | 著者 | Veverka, V. | 登録日 | 2020-07-23 | 公開日 | 2021-12-01 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | A ubiquitous disordered protein interaction module orchestrates transcription elongation. Science, 374, 2021
|
|
6ZV2
| TFIIS N-terminal domain (TND) from human PPP1R10 | 分子名称: | Serine/threonine-protein phosphatase 1 regulatory subunit 10 | 著者 | Veverka, V. | 登録日 | 2020-07-23 | 公開日 | 2021-12-01 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | A ubiquitous disordered protein interaction module orchestrates transcription elongation. Science, 374, 2021
|
|
6ZV1
| |
6ZUZ
| |
6ZUY
| Human TFIIS N-terminal domain (TND) | 分子名称: | Transcription elongation factor A protein 1 | 著者 | Veverka, V. | 登録日 | 2020-07-23 | 公開日 | 2021-12-01 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | A ubiquitous disordered protein interaction module orchestrates transcription elongation. Science, 374, 2021
|
|
6VTI
| Solution NMR structure of the N-terminal domain of the Serine/threonine-protein phosphatase 1 regulatory subunit 10, PPP1R10 | 分子名称: | Serine/threonine-protein phosphatase 1 regulatory subunit 10 | 著者 | Lemak, A, Wei, Y, Duan, S, Houliston, S, Penn, L.Z, Arrowsmith, C.H. | 登録日 | 2020-02-12 | 公開日 | 2020-02-26 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | The MYC oncoprotein directly interacts with its chromatin cofactor PNUTS to recruit PP1 phosphatase. Nucleic Acids Res., 50, 2022
|
|
6PX3
| Set2 bound to nucleosome | 分子名称: | DNA (145-MER), Histone H2B 1.1, Histone H3, ... | 著者 | Halic, M, Bilokapic, S. | 登録日 | 2019-07-24 | 公開日 | 2019-08-28 | 最終更新日 | 2019-09-04 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Nucleosome and ubiquitin position Set2 to methylate H3K36. Nat Commun, 10, 2019
|
|
6O9L
| Human holo-PIC in the closed state | 分子名称: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | 著者 | Yan, C.L, Dodd, T, He, Y, Tainer, J.A, Tsutakawa, S.E, Ivanov, I. | 登録日 | 2019-03-14 | 公開日 | 2019-05-29 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (7.2 Å) | 主引用文献 | Transcription preinitiation complex structure and dynamics provide insight into genetic diseases. Nat.Struct.Mol.Biol., 26, 2019
|
|
6NZO
| Set2 bound to nucleosome | 分子名称: | DNA (149-MER), Histone H2B 1.1, Histone H3, ... | 著者 | Halic, M, Bilokapic, S. | 登録日 | 2019-02-14 | 公開日 | 2019-08-28 | 最終更新日 | 2019-09-04 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Nucleosome and ubiquitin position Set2 to methylate H3K36. Nat Commun, 10, 2019
|
|
5ODD
| HUMAN MED26 N-TERMINAL DOMAIN (1-92) | 分子名称: | Mediator of RNA polymerase II transcription subunit 26 | 著者 | Lens, Z, Cantrelle, F.-X, Perruzini, R, Dewitte, F, Hanoulle, X, Villeret, V, Verger, A, Landrieu, I. | 登録日 | 2017-07-05 | 公開日 | 2017-11-29 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | 1H, 15N and 13C assignments of the N-terminal domain of the Mediator complex subunit MED26. Biomol.Nmr Assign., 10, 2016
|
|
5IYC
| Human core-PIC in the initial transcribing state | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ... | 著者 | He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. | 登録日 | 2016-03-24 | 公開日 | 2016-05-18 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Near-atomic resolution visualization of human transcription promoter opening. Nature, 533, 2016
|
|
5IYB
| Human core-PIC in the open state | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ... | 著者 | He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. | 登録日 | 2016-03-24 | 公開日 | 2016-05-18 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Near-atomic resolution visualization of human transcription promoter opening. Nature, 533, 2016
|
|
5IYA
| Human core-PIC in the closed state | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ... | 著者 | He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. | 登録日 | 2016-03-24 | 公開日 | 2016-05-18 | 最終更新日 | 2019-11-20 | 実験手法 | ELECTRON MICROSCOPY (5.4 Å) | 主引用文献 | Near-atomic resolution visualization of human transcription promoter opening. Nature, 533, 2016
|
|
5IY8
| Human holo-PIC in the initial transcribing state | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ... | 著者 | He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. | 登録日 | 2016-03-24 | 公開日 | 2016-05-18 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (7.9 Å) | 主引用文献 | Near-atomic resolution visualization of human transcription promoter opening. Nature, 533, 2016
|
|
5IY7
| Human holo-PIC in the open state | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ... | 著者 | He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. | 登録日 | 2016-03-24 | 公開日 | 2016-05-18 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (8.6 Å) | 主引用文献 | Near-atomic resolution visualization of human transcription promoter opening. Nature, 533, 2016
|
|
5IY6
| Human holo-PIC in the closed state | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ... | 著者 | He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. | 登録日 | 2016-03-24 | 公開日 | 2016-05-18 | 最終更新日 | 2019-11-20 | 実験手法 | ELECTRON MICROSCOPY (7.2 Å) | 主引用文献 | Near-atomic resolution visualization of human transcription promoter opening. Nature, 533, 2016
|
|
3OAK
| |
3O8Z
| |
3NFQ
| |
2XPP
| Crystal structure of a Spt6-Iws1(Spn1) complex from Encephalitozoon cuniculi, Form III | 分子名称: | CHROMATIN STRUCTURE MODULATOR, IWS1 | 著者 | Diebold, M.-L, Koch, M, Cura, V, Cavarelli, J, Romier, C. | 登録日 | 2010-08-27 | 公開日 | 2010-11-17 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | The Structure of an Iws1/Spt6 Complex Reveals an Interaction Domain Conserved in Tfiis, Elongin a and Med26 Embo J., 29, 2010
|
|