PDB: 84 件ウェブページステータス検索Chemie searchBIRD

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1OJ4	Ternary complex of 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 分子名称: 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL, 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE, CHLORIDE ION, ... 著者 Miallau, L, Alphey, M.S, Hunter, W.N. 登録日 2003-06-30 公開日 2003-07-31 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Biosynthesis of Isoprenoids: Crystal Structure of 4-Diphosphocytidyl-2C-Methyl-D-Erythritol Kinase Proc.Natl.Acad.Sci.USA, 100, 2003
2HFU	Crystal structure of L. major mevalonate kinase in complex with R-mevalonate 分子名称: (R)-MEVALONATE, Mevalonate kinase, putative 著者 Sgraja, T, Hunter, W.N. 登録日 2006-06-26 公開日 2007-04-17 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure, substrate recognition and reactivity of Leishmania major mevalonate kinase. Bmc Struct.Biol., 7, 2007
2HFS	Crystal structure of L. major mevalonate kinase 分子名称: Mevalonate kinase, putative 著者 Sgraja, T, Hunter, W.N. 登録日 2006-06-26 公開日 2007-04-17 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structure, substrate recognition and reactivity of Leishmania major mevalonate kinase. Bmc Struct.Biol., 7, 2007
2A2C	x-ray structure of human N-acetyl galactosamine kinase complexed with Mg-ADP and N-acetyl galactosamine 1-phosphate 分子名称: 2-acetamido-2-deoxy-1-O-phosphono-alpha-D-galactopyranose, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... 著者 Thoden, J.B, Holden, H.M. 登録日 2005-06-22 公開日 2005-07-26 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 The molecular architecture of human N-acetylgalactosamine kinase. J.Biol.Chem., 280, 2005
2R42	The Biochemical and Structural Basis for feedback Inhibition of Mevalonate Kinase and Isoprenoid Metabolism 分子名称: MAGNESIUM ION, Mevalonate kinase, S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE 著者 Fu, Z, Voynova, N.E, Miziorko, H.M, Kim, J.P. 登録日 2007-08-30 公開日 2008-06-24 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Biochemical and Structural Basis for Feedback Inhibition of Mevalonate Kinase and Isoprenoid Metabolism. Biochemistry, 47, 2008
2R3V	The Biochemical and Structural Basis for Feedback Inhibition of Mevalonate Kinase and Isoprenoid Metabolism 分子名称: Mevalonate kinase 著者 Fu, Z, Voynova, N.E, Miziorko, H.M, Kim, J.P. 登録日 2007-08-30 公開日 2008-06-24 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Biochemical and Structural Basis for Feedback Inhibition of Mevalonate Kinase and Isoprenoid Metabolism. Biochemistry, 47, 2008
4ED4	Crystal structure of IspE (4-diphosphocytidyl-2-C-methyl-D-erythritol kinase) from Mycobacterium abcessus, bound to ATP 分子名称: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, ADENOSINE-5'-TRIPHOSPHATE 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2012-03-26 公開日 2012-04-04 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
4EMD	Crystal structure of IspE (4-diphosphocytidyl-2-C-methyl-D-erythritol kinase) from Mycobacterium abcessus, bound to CMP and SO4 分子名称: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CYTIDINE-5'-MONOPHOSPHATE, SULFATE ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2012-04-11 公開日 2012-04-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
1K47	Crystal Structure of the Streptococcus pneumoniae Phosphomevalonate Kinase (PMK) 分子名称: phosphomevalonate kinase 著者 Romanowski, M.J, Bonanno, J.B, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2001-10-05 公開日 2002-05-08 最終更新日 2021-02-03 実験手法 X-RAY DIFFRACTION (2.42 Å) 主引用文献 Crystal structure of the Streptococcus pneumoniae phosphomevalonate kinase, a member of the GHMP kinase superfamily. Proteins, 47, 2002
6TEP	Crystal structure of a galactokinase from Bifidobacterium infantis in complex with ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Keenan, T, Parmeggiani, F, Fontenelle, C.Q, Malassis, J, Vendeville, J, Offen, W.A, Both, P, Huang, K, Marchesi, A, Heyam, A, Young, C, Charnock, S, Davies, G.J, Linclau, B, Flitsch, S.L, Fascione, M.A. 登録日 2019-11-12 公開日 2020-06-10 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Profiling Substrate Promiscuity of Wild-Type Sugar Kinases for Multi-fluorinated Monosaccharides. Cell Chem Biol, 27, 2020
6TEQ	Crystal structure of a galactokinase from Bifidobacterium infantis in complex with 2-deoxy-2-fluoro-galactose 分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-deoxy-2-fluoro-alpha-D-galactopyranose, ... 著者 Keenan, T, Parmeggiani, F, Fontenelle, C.Q, Malassis, J, Vendeville, J, Offen, W.A, Both, P, Huang, K, Marchesi, A, Heyam, A, Young, C, Charnock, S, Davies, G.J, Linclau, B, Flitsch, S.L, Fascione, M.A. 登録日 2019-11-12 公開日 2020-06-10 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.44 Å) 主引用文献 Profiling Substrate Promiscuity of Wild-Type Sugar Kinases for Multi-fluorinated Monosaccharides. Cell Chem Biol, 27, 2020
6TER	Crystal structure of a galactokinase from Bifidobacterium infantis in complex with Galactose 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Keenan, T, Parmeggiani, F, Fontenelle, C.Q, Malassis, J, Vendeville, J, Offen, W.A, Both, P, Huang, K, Marchesi, A, Heyam, A, Young, C, Charnock, S, Davies, G.J, Linclau, B, Flitsch, S.L, Fascione, M.A. 登録日 2019-11-12 公開日 2020-06-10 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Profiling Substrate Promiscuity of Wild-Type Sugar Kinases for Multi-fluorinated Monosaccharides. Cell Chem Biol, 27, 2020
1KKH	Crystal Structure of the Methanococcus jannaschii Mevalonate Kinase 分子名称: 1,4-DIETHYLENE DIOXIDE, Mevalonate Kinase 著者 Yang, D, Shipman, L.W, Roessner, C.A, Scott, A.I, Sacchettini, J.C. 登録日 2001-12-08 公開日 2002-03-27 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure of the Methanococcus jannaschii mevalonate kinase, a member of the GHMP kinase superfamily. J.Biol.Chem., 277, 2002
4HAC	Crystal Structure of the Mevalonate Kinase from an Archaeon Methanosarcina mazei 分子名称: MAGNESIUM ION, Mevalonate kinase 著者 Zhuang, N, Lee, K.H. 登録日 2012-09-26 公開日 2012-12-12 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Crystallization and preliminary X-ray diffraction analysis of mevalonate kinase from Methanosarcina mazei. Acta Crystallogr.,Sect.F, 68, 2012
2WW4	a triclinic crystal form of E. coli 4-diphosphocytidyl-2C-methyl-D- erythritol kinase 分子名称: 4-DIPHOSPHOCYTIDYL-2C-METHYL-D-ERYTHRITOL KINASE, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL 著者 Kalinowska-Tluscik, J, Miallau, L, Gabrielsen, M, Leonard, G.A, McSweeney, S.M, Hunter, W.N. 登録日 2009-10-21 公開日 2010-03-09 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A Triclinic Crystal Form of Escherichia Coli 4-Diphosphocytidyl-2C-Methyl-D-Erythritol Kinase and Reassessment of the Quaternary Structure. Acta Crystallogr.,Sect.F, 66, 2010
1KVK	The Structure of Binary complex between a Mammalian Mevalonate Kinase and ATP: Insights into the Reaction Mechanism and Human Inherited Disease 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, mevalonate kinase 著者 Fu, Z, Wang, M, Potter, D, Mizioko, H.M, Kim, J.J. 登録日 2002-01-26 公開日 2002-03-27 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The Structure of a Binary complex between a Mammalian Mevalonate Kinase and ATP: Insights into the Reaction Mechanism and Human Inherited Disease J.Biol.Chem., 277, 2002
4UT4	Burkholderia pseudomallei heptokinase WcbL, D-mannose complex. 分子名称: CHLORIDE ION, PUTATIVE SUGAR KINASE, alpha-D-mannopyranose 著者 Vivoli, M, Isupov, M.N, Nicholas, R, Hill, A, Scott, A, Kosma, P, Prior, J, Harmer, N.J. 登録日 2014-07-18 公開日 2016-01-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Unraveling the B.Pseudomallei Heptokinase Wcbl: From Structure to Drug Discovery. Chem.Biol., 22, 2015
3GON	Streptococcus pneumoniae Phosphomevalonate Kinase in Complex with Phosphomevalonate and AMPPNP 分子名称: (3R)-3-HYDROXY-3-METHYL-5-(PHOSPHONOOXY)PENTANOIC ACID, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... 著者 Andreassi, J.L, Bilder, P.W, Vetting, M.W, Roderick, S.L, Leyh, T.S. 登録日 2009-03-19 公開日 2009-07-21 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure of the ternary complex of phosphomevalonate kinase: the enzyme and its family Biochemistry, 48, 2009
4USK	Unravelling the B. pseudomallei heptokinase WcbL: from Structure to Drug Discovery. 分子名称: CHLORIDE ION, DIMETHYL SULFOXIDE, PUTATIVE SUGAR KINASE, ... 著者 Vivoli, M, Isupov, M.N, Nicholas, R, Hill, A, Scott, A, Kosma, P, Prior, J, Harmer, N.J. 登録日 2014-07-09 公開日 2016-01-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Unraveling the B.Pseudomallei Heptokinase Wcbl: From Structure to Drug Discovery. Chem.Biol., 22, 2015
4UTG	Burkholderia pseudomallei heptokinase WcbL,AMPPNP (ATP analogue) complex. 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, MAGNESIUM ION, ... 著者 Vivoli, M, Isupov, M.N, Nicholas, R, Hill, A, Scott, A, Kosma, P, Prior, J, Harmer, N.J. 登録日 2014-07-21 公開日 2016-01-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Unraveling the B.Pseudomallei Heptokinase Wcbl: From Structure to Drug Discovery. Chem.Biol., 22, 2015
8QC7	New monoclinic EcIspE 分子名称: 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL, 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Hamid, R. 登録日 2023-08-25 公開日 2024-09-11 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 New monoclinic EcIspE To Be Published
8QCC	E.coli IspE in complex with a ligand (1) 分子名称: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Hamid, R. 登録日 2023-08-25 公開日 2024-09-11 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 E.coli IspE in complex with a ligand (1) To Be Published
4USM	WcbL complex with glycerol bound to sugar site 分子名称: CHLORIDE ION, GLYCEROL, PUTATIVE SUGAR KINASE 著者 Vivoli, M, Isupov, M.N, Nicholas, R, Hill, A, Scott, A, Kosma, P, Prior, J, Harmer, N.J. 登録日 2014-07-10 公開日 2016-01-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Unraveling the B.Pseudomallei Heptokinase Wcbl: From Structure to Drug Discovery. Chem.Biol., 22, 2015
8QCO	E.coli IspE in complex with a ligand (3) 分子名称: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, ADENOSINE-5'-DIPHOSPHATE, ~{N}-[3-(4-azanyl-2-oxidanylidene-1~{H}-pyrimidin-5-yl)prop-2-ynyl]cyclopentanesulfonamide 著者 Hamid, R. 登録日 2023-08-28 公開日 2024-09-11 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 E.coli IspE in complex with a ligand (3) To Be Published
8QCN	E.coli IspE in complex with a ligand (2) 分子名称: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, ADENOSINE-5'-DIPHOSPHATE, ~{N}-[3-(4-azanyl-2-oxidanylidene-1~{H}-pyrimidin-5-yl)prop-2-ynyl]cyclopropanesulfonamide 著者 Hamid, R. 登録日 2023-08-27 公開日 2024-09-11 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 E.coli IspE in complex with a ligand (2) To Be Published

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