6TEQ

Crystal structure of a galactokinase from Bifidobacterium infantis in complex with 2-deoxy-2-fluoro-galactose

Summary for 6TEQ

• Entry DOI: 10.2210/pdb6teq/pdb
• Descriptor: Galactokinase, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ... (10 entities in total)
• Functional Keywords: 2fgal, complex, galactokinase, transferase
• Biological source: Bifidobacterium longum subsp. infantis ATCC 15697 = JCM 1222 = DSM 20088
• Total number of polymer chains: 4
• Total formula weight: 188875.16

Authors

Keenan, T.,Parmeggiani, F.,Fontenelle, C.Q.,Malassis, J.,Vendeville, J.,Offen, W.A.,Both, P.,Huang, K.,Marchesi, A.,Heyam, A.,Young, C.,Charnock, S.,Davies, G.J.,Linclau, B.,Flitsch, S.L.,Fascione, M.A. (deposition date: 2019-11-12, release date: 2020-06-10, Last modification date: 2024-01-24)

• Primary citation: Keenan, T.,Parmeggiani, F.,Malassis, J.,Fontenelle, C.Q.,Vendeville, J.B.,Offen, W.,Both, P.,Huang, K.,Marchesi, A.,Heyam, A.,Young, C.,Charnock, S.J.,Davies, G.J.,Linclau, B.,Flitsch, S.L.,Fascione, M.A.; Profiling Substrate Promiscuity of Wild-Type Sugar Kinases for Multi-fluorinated Monosaccharides.; Cell Chem Biol, 27:1199-, 2020; PubMed: 32619452; DOI: 10.1016/j.chembiol.2020.06.005

Experimental method

X-RAY DIFFRACTION (1.44 Å)