6TEQ

Crystal structure of a galactokinase from Bifidobacterium infantis in complex with 2-deoxy-2-fluoro-galactose

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Galactokinase	polymer	429	45815.4	4	UniProt (B7GUI0) Pfam (PF10509) Pfam (PF00288) Pfam (PF08544) In PDB	Bifidobacterium longum subsp. infantis ATCC 15697 = JCM 1222 = DSM 20088
2	A	2-(N-MORPHOLINO)-ETHANESULFONIC ACID	non-polymer		195.2	2	Chemie (MES)
3	C, A, B, D	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	17	Chemie (PEG)
4	D, C, A, B	GLYCEROL	non-polymer		92.1	14	Chemie (GOL)
5	D, A, C, B	2-deoxy-2-fluoro-alpha-D-galactopyranose	non-polymer		182.1	4	Chemie (GAF)
6	A, C, B, D	2-deoxy-2-fluoro-beta-D-galactopyranose	non-polymer		182.1	4	Chemie (2FG)
7	B, D, A, C	CHLORIDE ION	non-polymer		35.5	7	Chemie (CL)
8	C, B	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
9	C	TRIETHYLENE GLYCOL	non-polymer		150.2	2	Chemie (PGE)
10		water	water		18.0	1571	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 416 (UniProt: B7GUI0)

PDB	External Database	Details
Lys 417	-	expression tag
Leu 418	-	expression tag
Ala 419	-	expression tag
Ala 420	-	expression tag
Ala 421	-	expression tag
Leu 422	-	expression tag
Glu 423	-	expression tag
His 424	-	expression tag
His 425	-	expression tag
His 426	-	expression tag
His 427	-	expression tag
His 428	-	expression tag
His 429	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	183261.5
Non-Polymers*	Number of molecules	52
	Total formula weight	5613.7
All*	Total formula weight	188875.2

*Water molecules are not included.