4Q7G
 
 | | 1.7 Angstrom Crystal Structure of leukotoxin LukD from Staphylococcus aureus. | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Leucotoxin LukDv | | 著者 | Minasov, G, Nocadello, S, Shuvalova, L, Shatsman, S, Kwon, K, Bagnoli, F, Falugi, F, Bottomley, M, Grandi, G, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2014-04-24 | | 公開日 | 2014-05-07 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structures of the components of the Staphylococcus aureus leukotoxin ED.
Acta Crystallogr D Struct Biol, 72, 2016
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4H56
 | | Crystal structure of the Clostridium perfringens NetB toxin in the membrane inserted form | | 分子名称: | Necrotic enteritis toxin B | | 著者 | Savva, C.G, Fernandes da Costa, S.P, Bokori-Brown, M, Naylor, C, Cole, A.R, Moss, D.S, Titball, R.W, Basak, A.K. | | 登録日 | 2012-09-18 | | 公開日 | 2012-12-26 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | | 主引用文献 | Molecular Architecture and Functional Analysis of NetB, a Pore-forming Toxin from Clostridium perfringens.
J.Biol.Chem., 288, 2013
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4I0N
 | | Pore forming protein | | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, Necrotic enteritis toxin B | | 著者 | Yan, X, Porter, C.J, Hardy, S.P, Steer, D, Smith, A.I, Quinset, N, Hughes, V, Cheung, J.K, Keyburn, A.L, Kaldhusdal, M, Moore, R.J, Bannam, T.L, Whisstock, J.C, Rood, J.I. | | 登録日 | 2012-11-16 | | 公開日 | 2013-03-20 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural and functional analysis of the pore-forming toxin NetB from Clostridium perfringens
MBio, 4, 2013
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4P24
 | | pore forming toxin | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Alpha-hemolysin | | 著者 | Sugawara, T, Yamashita, D, Tanaka, Y, Tanaka, I, Yao, M. | | 登録日 | 2014-03-01 | | 公開日 | 2015-03-11 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural basis for pore-forming mechanism of staphylococcal alpha-hemolysin.
Toxicon, 108, 2015
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4IDJ
 | | S.Aureus a-hemolysin monomer in complex with Fab | | 分子名称: | Alpha-hemolysin, Fab Heavy chain, Fab Light chain, ... | | 著者 | Strop, P. | | 登録日 | 2012-12-12 | | 公開日 | 2013-06-26 | | 最終更新日 | 2021-05-26 | | 実験手法 | X-RAY DIFFRACTION (3.36 Å) | | 主引用文献 | Mechanism of Action and In Vivo Efficacy of a Human-Derived Antibody against Staphylococcus aureus alpha-Hemolysin.
J.Mol.Biol., 425, 2013
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4IYC
 | | Structure of the T244A mutant of the PANTON-VALENTINE LEUCOCIDIN component from STAPHYLOCOCCUS AUREUS | | 分子名称: | LukS-PV | | 著者 | Maveyraud, L, Guerin, F, Lavnetie, B.J, Prevost, G, Mourey, L. | | 登録日 | 2013-01-28 | | 公開日 | 2014-01-29 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Residues essential for panton-valentine leukocidin s component binding to its cell receptor suggest both plasticity and adaptability in its interaction surface
Plos One, 9, 2014
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7P93
 | | Crystal Structure of leukotoxin LukE from Staphylococcus aureus in complex with a sulfated ACKR1 N-terminal peptide | | 分子名称: | Atypical chemokine receptor 1, Leucotoxin LukEv | | 著者 | Lambey, P, Hoh, F, Peysson, F, Granier, S, Leyrat, C. | | 登録日 | 2021-07-23 | | 公開日 | 2022-04-06 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Structural insights into recognition of chemokine receptors by Staphylococcus aureus leukotoxins.
Elife, 11, 2022
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7P8T
 | | Crystal Structure of leukotoxin LukE from Staphylococcus aureus at 1.5 Angstrom resolution | | 分子名称: | CHLORIDE ION, Leucotoxin LukEv | | 著者 | Lambey, P, Hoh, F, Granier, S, Leyrat, C. | | 登録日 | 2021-07-23 | | 公開日 | 2022-04-06 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.459 Å) | | 主引用文献 | Structural insights into recognition of chemokine receptors by Staphylococcus aureus leukotoxins.
Elife, 11, 2022
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7P8U
 | | Crystal Structure of leukotoxin LukE from Staphylococcus aureus in complex with p-cresyl sulfate | | 分子名称: | (4-methylphenyl) hydrogen sulfate, DI(HYDROXYETHYL)ETHER, IMIDAZOLE, ... | | 著者 | Lambey, P, Hoh, F, Peysson, F, Granier, S, Leyrat, C. | | 登録日 | 2021-07-23 | | 公開日 | 2022-04-06 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural insights into recognition of chemokine receptors by Staphylococcus aureus leukotoxins.
Elife, 11, 2022
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7P8S
 | | Crystal Structure of leukotoxin LukE from Staphylococcus aureus at 1.9 Angstrom resolution | | 分子名称: | (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, HEXAETHYLENE GLYCOL, Leucotoxin LukEv, ... | | 著者 | Lambey, P, Hoh, F, Granier, S, Leyrat, C. | | 登録日 | 2021-07-23 | | 公開日 | 2022-04-06 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural insights into recognition of chemokine receptors by Staphylococcus aureus leukotoxins.
Elife, 11, 2022
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7P8X
 | | Crystal Structure of leukotoxin LukE from Staphylococcus aureus in complex with a doubly sulfated CCR2 N-terminal peptide | | 分子名称: | C-C chemokine receptor type 2, IMIDAZOLE, Leucotoxin LukEv, ... | | 著者 | Lambey, P, Hoh, F, Peysson, F, Granier, S, Leyrat, C. | | 登録日 | 2021-07-23 | | 公開日 | 2022-04-06 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structural insights into recognition of chemokine receptors by Staphylococcus aureus leukotoxins.
Elife, 11, 2022
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3M3R
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3M4D
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3M2L
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3M4E
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3LKF
 | | LEUKOCIDIN F (HLGB) FROM STAPHYLOCOCCUS AUREUS WITH PHOSPHOCHOLINE BOUND | | 分子名称: | LEUKOCIDIN F SUBUNIT, PHOSPHOCHOLINE | | 著者 | Olson, R, Nariya, H, Yokota, K, Kamio, Y, Gouaux, J.E. | | 登録日 | 1998-07-28 | | 公開日 | 1999-07-28 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of staphylococcal LukF delineates conformational changes accompanying formation of a transmembrane channel.
Nat.Struct.Biol., 6, 1999
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6U2S
 | | Structure-based discovery of a novel small-molecule inhibitor of methicillin-resistant S. aureus | | 分子名称: | Bi-component leukocidin LukED subunit D, fos-choline-14 | | 著者 | Liu, J, Kozhaya, L, Torres, V.J, Unutmaz, D, Lu, M. | | 登録日 | 2019-08-20 | | 公開日 | 2020-03-25 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structure-based discovery of a small-molecule inhibitor of methicillin-resistantStaphylococcus aureusvirulence.
J.Biol.Chem., 295, 2020
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6U33
 | | Structure-based discovery of a novel small-molecule inhibitor of methicillin-resistant S. aureus | | 分子名称: | Bi-component leukocidin LukED subunit D, NICKEL (II) ION | | 著者 | Liu, J, Kozhaya, L, Torres, V.J, Unutmaz, D, Lu, M. | | 登録日 | 2019-08-21 | | 公開日 | 2020-03-25 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structure-based discovery of a small-molecule inhibitor of methicillin-resistantStaphylococcus aureusvirulence.
J.Biol.Chem., 295, 2020
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6U3F
 | | Structure-based discovery of a novel small-molecule inhibitor of methicillin-resistant S. aureus | | 分子名称: | Panton-Valentine Leucocidin F, SULFATE ION, fos-choline-14 | | 著者 | Liu, J, Kozhaya, L, Torres, V.J, Unutmaz, D, Lu, M. | | 登録日 | 2019-08-21 | | 公開日 | 2020-03-25 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Structure-based discovery of a small-molecule inhibitor of methicillin-resistantStaphylococcus aureusvirulence.
J.Biol.Chem., 295, 2020
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6U3T
 | | Structure-based discovery of a novel small-molecule inhibitor of methicillin-resistant S. aureus | | 分子名称: | Alpha-hemolysin, SULFATE ION, fos-choline-14 | | 著者 | Liu, J, Kozhaya, L, Torres, V.J, Unutmaz, D, Lu, M. | | 登録日 | 2019-08-22 | | 公開日 | 2020-03-25 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | | 主引用文献 | Structure-based discovery of a small-molecule inhibitor of methicillin-resistantStaphylococcus aureusvirulence.
J.Biol.Chem., 295, 2020
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6U4P
 | | Structure-based discovery of a novel small-molecule inhibitor of methicillin-resistant S. aureus | | 分子名称: | Alpha-hemolysin, SULFATE ION, fos-choline-14 | | 著者 | Liu, J, Kozhaya, L, Torres, V.J, Unutmaz, D, Lu, M. | | 登録日 | 2019-08-26 | | 公開日 | 2020-03-25 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | | 主引用文献 | Structure-based discovery of a small-molecule inhibitor of methicillin-resistantStaphylococcus aureusvirulence.
J.Biol.Chem., 295, 2020
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1XEZ
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7YL9
 | | Cryo-EM structure of complete transmembrane channel E289A mutant Vibrio cholerae Cytolysin | | 分子名称: | Hemolysin | | 著者 | Mondal, A.K, Sengupta, N, Singh, M, Biswas, R, Lata, K, Lahiri, I, Dutta, S, Chattopadhyay, K. | | 登録日 | 2022-07-25 | | 公開日 | 2022-08-31 | | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | | 主引用文献 | Cryo-EM structure of complete transmembrane channel E289A mutant Vibrio cholerae Cytolysin
J.Biol.Chem.
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3O44
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7O1Q
 | | Amyloid beta oligomer displayed on the alpha hemolysin scaffold | | 分子名称: | Alpha-hemolysin hybridized Abeta | | 著者 | Wu, J, Blum, T.B, Farrell, D.P, DiMaio, F, Abrahams, J.P, Luo, J. | | 登録日 | 2021-03-30 | | 公開日 | 2021-04-14 | | 最終更新日 | 2021-08-18 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Cryo-electron Microscopy Imaging of Alzheimer's Amyloid-beta 42 Oligomer Displayed on a Functionally and Structurally Relevant Scaffold.
Angew.Chem.Int.Ed.Engl., 60, 2021
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