7P8X

Crystal Structure of leukotoxin LukE from Staphylococcus aureus in complex with a doubly sulfated CCR2 N-terminal peptide

Summary for 7P8X

Entry DOI	10.2210/pdb7p8x/pdb
Descriptor	Leucotoxin LukEv, C-C chemokine receptor type 2, IMIDAZOLE, ... (5 entities in total)
Functional Keywords	leukotoxin, beta barrel pore forming toxin, cytolysis, hemolysis, toxin
Biological source	Staphylococcus aureus More
Total number of polymer chains	2
Total formula weight	35765.66
Authors	Lambey, P.,Hoh, F.,Peysson, F.,Granier, S.,Leyrat, C. (deposition date: 2021-07-23, release date: 2022-04-06, Last modification date: 2024-01-31)
Primary citation	Lambey, P.,Otun, O.,Cong, X.,Hoh, F.,Brunel, L.,Verdie, P.,Grison, C.M.,Peysson, F.,Jeannot, S.,Durroux, T.,Bechara, C.,Granier, S.,Leyrat, C. Structural insights into recognition of chemokine receptors by Staphylococcus aureus leukotoxins. Elife, 11:-, 2022 Cited by PubMed: 35311641 DOI: 10.7554/eLife.72555 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.4 Å)

Structure validation