7P8X

Crystal Structure of leukotoxin LukE from Staphylococcus aureus in complex with a doubly sulfated CCR2 N-terminal peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Leucotoxin LukEv	polymer	308	34686.7	1	UniProt (Q2FXB0) Pfam (PF07968) In PDB	Staphylococcus aureus	Variant of LukE
2	M	C-C chemokine receptor type 2	polymer	6	817.8	1	UniProt (P41597) In PDB	Homo sapiens	C-C CKR-2,CC-CKR-2,CCR-2,CCR2,Monocyte chemoattractant protein 1 receptor,MCP-1-R
3	A	IMIDAZOLE	non-polymer		69.1	1	Chemie (IMD)
4	A	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
5		water	water		18.0	295	Chemie (HOH)

Sequence modifications

A: 12 - 311 (UniProt: Q2FXB0)

PDB	External Database	Details
Met 11	-	initiating methionine
Lys 312	-	expression tag
His 313	-	expression tag
His 314	-	expression tag
His 315	-	expression tag
His 316	-	expression tag
His 317	-	expression tag
His 318	-	expression tag

M: 25 - 29 (UniProt: P41597)

PDB	External Database	Details
Ace 24	-	acetylation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	35504.4
Non-Polymers*	Number of molecules	3
	Total formula weight	261.2
All*	Total formula weight	35765.7

*Water molecules are not included.