7P8X
Crystal Structure of leukotoxin LukE from Staphylococcus aureus in complex with a doubly sulfated CCR2 N-terminal peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Leucotoxin LukEv | polymer | 308 | 34686.7 | 1 | UniProt (Q2FXB0) Pfam (PF07968) | Staphylococcus aureus | Variant of LukE |
| 2 | B (M) | C-C chemokine receptor type 2 | polymer | 6 | 817.8 | 1 | UniProt (P41597) | Homo sapiens | C-C CKR-2,CC-CKR-2,CCR-2,CCR2,Monocyte chemoattractant protein 1 receptor,MCP-1-R |
| 3 | C (A) | IMIDAZOLE | non-polymer | 69.1 | 1 | Chemie (IMD) | |||
| 4 | D, E (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | F, G (A, M) | water | water | 18.0 | 295 | Chemie (HOH) |
Sequence modifications
A: 12 - 311 (UniProt: Q2FXB0)
M: 25 - 29 (UniProt: P41597)
| PDB | External Database | Details |
|---|---|---|
| Met 11 | - | initiating methionine |
| Lys 312 | - | expression tag |
| His 313 | - | expression tag |
| His 314 | - | expression tag |
| His 315 | - | expression tag |
| His 316 | - | expression tag |
| His 317 | - | expression tag |
| His 318 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ace 24 | - | acetylation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35504.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 261.2 | |
| All* | Total formula weight | 35765.7 |
