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7KPG
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BU of 7kpg by Molmil
Blocking Fab 25 anti-SIRP-alpha antibody in complex with SIRP-alpha Variant 1
分子名称: Heavy chain of Fab 25 anti-SIRP-alpha antibody, Light chain of Fab 25 anti-SIRP-alpha antibody, SULFATE ION, ...
著者Sim, J, Pons, J.
登録日2020-11-11
公開日2020-12-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Targeting the myeloid checkpoint receptor SIRP alpha potentiates innate and adaptive immune responses to promote anti-tumor activity.
J Hematol Oncol, 13, 2020
6VRR
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BU of 6vrr by Molmil
Crystal structure of a disease mutant of the Voltage-gated Sodium Channel Beta 2 subunit extracellular domain
分子名称: GLYCEROL, Sodium channel subunit beta-2
著者Das, S, Van Petegem, F.
登録日2020-02-09
公開日2020-08-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Biophysical Investigation of Sodium Channel Interaction with beta-Subunit Variants Associated with Arrhythmias.
Bioelectricity, 2, 2020
4WHD
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BU of 4whd by Molmil
Human CEACAM1 N-domain homodimer
分子名称: Carcinoembryonic antigen-related cell adhesion molecule 1, GLYCEROL, octyl beta-D-glucopyranoside
著者Kirouac, K.N, Prive, G.G.
登録日2014-09-22
公開日2015-10-07
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Human CEACAM1 N-domain homodimer
To Be Published
4WHC
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BU of 4whc by Molmil
Human CEACAM6 N-domain
分子名称: Carcinoembryonic antigen-related cell adhesion molecule 6, ZINC ION
著者Prive, G.G, Kirouac, K.N.
登録日2014-09-22
公開日2015-10-07
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.705 Å)
主引用文献Human CEACAM6 N-domain
To Be Published
8EQ6
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BU of 8eq6 by Molmil
PD1 signaling receptor bound to FAB Complex
分子名称: Antibody FAB heavy chain, Antibody FAB light chain, Programmed cell death protein 1
著者Bjorkelid, C, Paluch, C, Robertson, N.J.
登録日2022-10-07
公開日2023-10-11
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Antibody agonists trigger immune receptor signaling through local exclusion of receptor-type protein tyrosine phosphatases.
Immunity, 57, 2024
4WEN
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BU of 4wen by Molmil
Co-complex structure of the F4 fimbrial adhesin FaeG variant ac with llama single domain antibody V2
分子名称: Anti-F4+ETEC bacteria VHH variable region, K88 fimbrial protein AC
著者Moonens, K, Van den Broeck, I, Pardon, E, De Kerpel, M, Remaut, H, De Greve, H.
登録日2014-09-10
公開日2015-02-04
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Structural insight in the inhibition of adherence of F4 fimbriae producing enterotoxigenic Escherichia coli by llama single domain antibodies.
Vet. Res., 46, 2015
4WEM
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BU of 4wem by Molmil
Co-complex structure of the F4 fimbrial adhesin FaeG variant ac with llama single domain antibody V1
分子名称: Anti-F4+ETEC bacteria VHH variable region, K88 fimbrial protein AC, PHOSPHATE ION
著者Moonens, K, Van den Broeck, I, Pardon, E, De Kerpel, M, Remaut, H, De Greve, H.
登録日2014-09-10
公開日2015-02-04
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural insight in the inhibition of adherence of F4 fimbriae producing enterotoxigenic Escherichia coli by llama single domain antibodies.
Vet. Res., 46, 2015
4WTZ
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BU of 4wtz by Molmil
Human CEACAM6-CEACAM8 N-domain heterodimer complex
分子名称: Carcinoembryonic antigen-related cell adhesion molecule 6, Carcinoembryonic antigen-related cell adhesion molecule 8, NICKEL (II) ION
著者Kirouac, K.N, Prive, G.G.
登録日2014-10-30
公開日2015-11-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献Human CEACAM6-CEACAM8 N-domain heterodimer complex
To Be Published
4WEU
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BU of 4weu by Molmil
Co-complex structure of the F4 fimbrial adhesin FaeG variant ad with llama single domain antibody V3
分子名称: Anti-F4+ETEC bacteria VHH variable region, K88 fimbrial protein AD
著者Moonens, K, Van den Broeck, I, Pardon, E, De Kerpel, M, Remaut, H, De Greve, H.
登録日2014-09-11
公開日2015-02-04
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Structural insight in the inhibition of adherence of F4 fimbriae producing enterotoxigenic Escherichia coli by llama single domain antibodies.
Vet. Res., 46, 2015
8GY5
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BU of 8gy5 by Molmil
High-resolution structure of the cemiplimab Fab in complex with PD-1
分子名称: Programmed cell death protein 1, heavy chain, light chain
著者Heo, Y.-S, Jeong, T.J.
登録日2022-09-21
公開日2023-10-04
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献High-resolution structure of the cemiplimab Fab in complex with PD-1
To Be Published
5B8C
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BU of 5b8c by Molmil
High resolution structure of the human PD-1 in complex with pembrolizumab Fv
分子名称: Pembrolizumab heavy chain variable region (PemVH), Pembrolizumab light chain variable region (PemVL), Programmed cell death protein 1
著者Horita, S, Shimamura, T, Iwata, S, Nomura, N.
登録日2016-06-14
公開日2016-10-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.146 Å)
主引用文献High-resolution crystal structure of the therapeutic antibody pembrolizumab bound to the human PD-1
Sci Rep, 6, 2016
5AYQ
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BU of 5ayq by Molmil
Structure-based site-directed photo-crosslinking analyses of multimeric cell-adhesive interactions of VGSC beta subunits
分子名称: Sodium channel subunit beta-4
著者Shimizu, H.
登録日2015-09-01
公開日2016-06-08
最終更新日2020-02-19
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure-based site-directed photo-crosslinking analyses of multimeric cell-adhesive interactions of voltage-gated sodium channel beta subunits
Sci Rep, 6, 2016
5B21
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BU of 5b21 by Molmil
Dimer structure of murine Nectin-1 D1
分子名称: murine Nectin-1 D1
著者Sangawa, T, Takebe, K, Suzuki, M.
登録日2015-12-28
公開日2016-12-28
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Dimer structure of murine Nectin-1 D1
To Be Published
6HIG
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BU of 6hig by Molmil
hPD-1/NBO1a Fab complex
分子名称: Heavy Chain, Light Chain, Programmed cell death protein 1
著者Loredo-Varela, J.L, Fenwick, C, Pantaleo, G, Weissenhorn, W.
登録日2018-08-29
公開日2019-06-05
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Tumor suppression of novel anti-PD-1 antibodies mediated through CD28 costimulatory pathway.
J.Exp.Med., 216, 2019
6IGO
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BU of 6igo by Molmil
Crystal structure of myelin protein zero-like protein 1 (MPZL1)
分子名称: Myelin protein zero-like protein 1
著者Yu, T.
登録日2018-09-25
公開日2018-11-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.746 Å)
主引用文献Structural and biochemical studies of the extracellular domain of Myelin protein zero-like protein 1
Biochem. Biophys. Res. Commun., 506, 2018
6IGT
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BU of 6igt by Molmil
MPZL1 mutant - V145G, Q146K, P147T and G148S
分子名称: Myelin protein zero-like protein 1
著者Yu, T.
登録日2018-09-26
公開日2018-11-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.404 Å)
主引用文献Structural and biochemical studies of the extracellular domain of Myelin protein zero-like protein 1
Biochem. Biophys. Res. Commun., 506, 2018
6IGW
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BU of 6igw by Molmil
MPZL1 mutant - S86G, V145G, Q146K,P147T,G148S
分子名称: Myelin protein zero-like protein 1
著者Yu, T.
登録日2018-09-26
公開日2018-11-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.979 Å)
主引用文献Structural and biochemical studies of the extracellular domain of Myelin protein zero-like protein 1
Biochem. Biophys. Res. Commun., 506, 2018
1Q8M
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BU of 1q8m by Molmil
Crystal structure of the human myeloid cell activating receptor TREM-1
分子名称: GLUTATHIONE, SULFATE ION, triggering receptor expressed on myeloid cells 1
著者Radaev, S, Kattah, M, Rostro, B, Colonna, M, Sun, P.D.
登録日2003-08-21
公開日2003-12-09
最終更新日2022-12-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of the human myeloid cell activating receptor TREM-1
Structure, 11, 2003
1QBL
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BU of 1qbl by Molmil
FAB E8 (FABE8A) X-RAY STRUCTURE AT 2.26 ANGSTROM RESOLUTION
分子名称: FABE8A
著者Mylvaganam, S.E, Paterson, Y, Getzoff, E.D.
登録日1998-04-29
公開日1998-12-02
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Structural basis for the binding of an anti-cytochrome c antibody to its antigen: crystal structures of FabE8-cytochrome c complex to 1.8 A resolution and FabE8 to 2.26 A resolution.
J.Mol.Biol., 281, 1998
1QFP
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BU of 1qfp by Molmil
N-TERMINAL DOMAIN OF SIALOADHESIN (MOUSE)
分子名称: PROTEIN (SIALOADHESIN)
著者May, A.P, Robinson, R.C, Burtnick, L, Crocker, P.R, Jones, E.Y.
登録日1999-04-12
公開日1999-04-16
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of the N-terminal domain of sialoadhesin in complex with 3' sialyllactose at 1.85 A resolution.
Mol.Cell, 1, 1998
1QD0
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BU of 1qd0 by Molmil
CAMELID HEAVY CHAIN VARIABLE DOMAINS PROVIDE EFFICIENT COMBINING SITES TO HAPTENS
分子名称: 3-HYDROXY-7-(4-{1-[2-HYDROXY-3-(2-HYDROXY-5-SULFO-PHENYLAZO)-BENZYL]-2-SULFO-ETHYLAMINO}-[1,2,5]TRIAZIN-2-YLAMINO)-2-(2-HYDROXY-5-SULFO-PHENYLAZO)-NAPTHALENE-1,8-DISULFONIC ACID, COPPER (II) ION, VHH-R2 ANTI-RR6 ANTIBODY
著者Spinelli, S, Frenken, L.G.J, Hermans, P, Verrips, T, Brown, K, Tegoni, M, Cambillau, C.
登録日1999-07-08
公開日2000-07-19
最終更新日2018-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Camelid heavy-chain variable domains provide efficient combining sites to haptens.
Biochemistry, 39, 2000
1QA9
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BU of 1qa9 by Molmil
Structure of a Heterophilic Adhesion Complex Between the Human CD2 and CD58(LFA-3) Counter-Receptors
分子名称: HUMAN CD2 PROTEIN, HUMAN CD58 PROTEIN
著者Wang, J.-H, Smolyar, A, Tan, K, Liu, J.-H, Kim, M, Sun, Z.J, Wagner, G, Reinherz, E.L.
登録日1999-04-13
公開日1999-04-29
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure of a heterophilic adhesion complex between the human CD2 and CD58 (LFA-3) counterreceptors.
Cell(Cambridge,Mass.), 97, 1999
1QFO
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BU of 1qfo by Molmil
N-TERMINAL DOMAIN OF SIALOADHESIN (MOUSE) IN COMPLEX WITH 3'SIALYLLACTOSE
分子名称: N-acetyl-alpha-neuraminic acid, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, PROTEIN (SIALOADHESIN)
著者May, A.P, Robinson, R.C, Vinson, M, Crocker, P.R, Jones, E.Y.
登録日1999-04-12
公開日1999-04-16
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of the N-terminal domain of sialoadhesin in complex with 3' sialyllactose at 1.85 A resolution.
Mol.Cell, 1, 1998
6RPJ
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BU of 6rpj by Molmil
A Non-blocking anti-CTLA-4 Nanobody complexed with CTLA-4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, A non-blocking CTLA-4 nanobody, Cytotoxic T-lymphocyte protein 4, ...
著者Gao, H, Zhou, A, Zhang, F.
登録日2019-05-14
公開日2020-07-08
最終更新日2020-11-11
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献A Non-blocking anti-CTLA-4 Nanobody complexed with CTLA-4
To Be Published
6RQM
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A blocking anti-CTLA-4 Nanobody (KN044) complexed with CTLA-4
分子名称: A blocking anti-CTLA-4 nanobody (KN044), Cytotoxic T-lymphocyte protein 4
著者Zhang, F, Zhou, A, Gao, H.
登録日2019-05-16
公開日2020-07-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A blocking anti-CTLA-4 Nanobody (KN044) complexed with CTLA-4
To Be Published

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