2UU7
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![BU of 2uu7 by Molmil](/molmil-images/mine/2uu7) | |
4ACF
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![BU of 4acf by Molmil](/molmil-images/mine/4acf) | CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS GLUTAMINE SYNTHETASE IN COMPLEX WITH IMIDAZOPYRIDINE INHIBITOR ((4-(6-BROMO-3-(BUTYLAMINO)IMIDAZO(1,2-A)PYRIDIN-2-YL)PHENOXY) ACETIC ACID) AND L-METHIONINE-S-SULFOXIMINE PHOSPHATE. | 分子名称: | CHLORIDE ION, GLUTAMINE SYNTHETASE 1, L-METHIONINE-S-SULFOXIMINE PHOSPHATE, ... | 著者 | Nilsson, M.T, Mowbray, S.L. | 登録日 | 2011-12-15 | 公開日 | 2012-10-24 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Synthesis, Biological Evaluation and X-Ray Crystallographic Studies of Imidazo(1,2-A)Pyridine-Based Mycobacterium Tuberculosis Glutamine Synthetase Inhibitors Medchemcomm, 3, 2012
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2OJW
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![BU of 2ojw by Molmil](/molmil-images/mine/2ojw) | Crystal structure of human glutamine synthetase in complex with ADP and phosphate | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, GLYCEROL, ... | 著者 | Karlberg, T, Uppenberg, J, Arrowsmith, C, Berglund, H, Busam, R.D, Collins, R, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hallberg, B.M, Hammarstrom, M, Hogbom, M, Johansson, I, Kotenyova, T, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, Van Den Berg, S, Wallden, K, Weigelt, J, Holmberg-Schiavone, L, Structural Genomics Consortium (SGC) | 登録日 | 2007-01-15 | 公開日 | 2007-03-13 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Crystal structures of mammalian glutamine synthetases illustrate substrate-induced conformational changes and provide opportunities for drug and herbicide design. J.Mol.Biol., 375, 2008
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2WGS
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![BU of 2wgs by Molmil](/molmil-images/mine/2wgs) | Crystal structure of Mycobacterium Tuberculosis Glutamine Synthetase in complex with a purine analogue inhibitor. | 分子名称: | 1-(3,4-dichlorobenzyl)-3,7-dimethyl-8-morpholin-4-yl-3,7-dihydro-1H-purine-2,6-dione, CHLORIDE ION, GLUTAMINE SYNTHETASE 1 | 著者 | Nilsson, M.T, Krajewski, W.W, Jones, T.A, Mowbray, S.L. | 登録日 | 2009-04-27 | 公開日 | 2009-09-01 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Structural Basis for the Inhibition of Mycobacterium Tuberculosis Glutamine Synthetase by Novel ATP-Competitive Inhibitors. J.Mol.Biol., 393, 2009
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2QC8
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![BU of 2qc8 by Molmil](/molmil-images/mine/2qc8) | Crystal structure of human glutamine synthetase in complex with ADP and methionine sulfoximine phosphate | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Glutamine synthetase, ... | 著者 | Karlberg, T, Lehtio, L, Arrowsmith, C.H, Berglund, H, Busam, R.D, Collins, R, Dahlgren, L.G, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hogbom, M, Johansson, I, Kallas, A, Kotenyova, T, Moche, M, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Sundstrom, M, Thorsell, A.G, Van Den Berg, S, Weigelt, J, Holmberg-Schiavone, L, Structural Genomics Consortium (SGC) | 登録日 | 2007-06-19 | 公開日 | 2007-07-03 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structures of mammalian glutamine synthetases illustrate substrate-induced conformational changes and provide opportunities for drug and herbicide design. J.Mol.Biol., 375, 2008
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2D3B
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![BU of 2d3b by Molmil](/molmil-images/mine/2d3b) | Crystal Structure of the Maize Glutamine Synthetase complexed with AMPPNP and Methionine sulfoximine | 分子名称: | (2S)-2-AMINO-4-(METHYLSULFONIMIDOYL)BUTANOIC ACID, MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Unno, H, Uchida, T, Sugawara, H, Kurisu, G, Sugiyama, T, Yamaya, T, Sakakibara, H, Hase, T, Kusunoki, M. | 登録日 | 2005-09-26 | 公開日 | 2006-07-18 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Atomic Structure of Plant Glutamine Synthetase: A KEY ENZYME FOR PLANT PRODUCTIVITY J.Biol.Chem., 281, 2006
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2D3A
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![BU of 2d3a by Molmil](/molmil-images/mine/2d3a) | Crystal Structure of the Maize Glutamine Synthetase complexed with ADP and Methionine sulfoximine Phosphate | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, L-METHIONINE-S-SULFOXIMINE PHOSPHATE, MANGANESE (II) ION, ... | 著者 | Unno, H, Uchida, T, Sugawara, H, Kurisu, G, Sugiyama, T, Yamaya, T, Sakakibara, H, Hase, T, Kusunoki, M. | 登録日 | 2005-09-26 | 公開日 | 2006-07-18 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | 主引用文献 | Atomic Structure of Plant Glutamine Synthetase: A KEY ENZYME FOR PLANT PRODUCTIVITY J.Biol.Chem., 281, 2006
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2D3C
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![BU of 2d3c by Molmil](/molmil-images/mine/2d3c) | Crystal Structure of the Maize Glutamine Synthetase complexed with ADP and Phosphinothricin Phosphate | 分子名称: | (2S)-2-AMINO-4-[METHYL(PHOSPHONOOXY)PHOSPHORYL]BUTANOIC ACID, ADENOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ... | 著者 | Unno, H, Uchida, T, Sugawara, H, Kurisu, G, Sugiyama, T, Yamaya, T, Sakakibara, H, Hase, T, Kusunoki, M. | 登録日 | 2005-09-26 | 公開日 | 2006-07-18 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (3.81 Å) | 主引用文献 | Atomic Structure of Plant Glutamine Synthetase: A KEY ENZYME FOR PLANT PRODUCTIVITY J.Biol.Chem., 281, 2006
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2BVC
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![BU of 2bvc by Molmil](/molmil-images/mine/2bvc) | Crystal structure of Mycobacterium tuberculosis glutamine synthetase in complex with a transition state mimic | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, GLUTAMINE SYNTHETASE 1, ... | 著者 | Krajewski, W.W, Jones, T.A, Mowbray, S.L. | 登録日 | 2005-06-23 | 公開日 | 2005-07-07 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure of Mycobacterium Tuberculosis Glutamine Synthetase in Complex with a Transition-State Mimic Provides Functional Insights. Proc.Natl.Acad.Sci.USA, 102, 2005
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8OOX
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![BU of 8oox by Molmil](/molmil-images/mine/8oox) | Glutamine synthetase from Methermicoccus shengliensis at a resolution of 3.09 A | 分子名称: | CITRIC ACID, GLYCEROL, Glutamine synthetase, ... | 著者 | Mueller, M.-C, Lemaire, O.N, Wagner, T. | 登録日 | 2023-04-06 | 公開日 | 2024-01-24 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.09 Å) | 主引用文献 | Differences in regulation mechanisms of glutamine synthetases from methanogenic archaea unveiled by structural investigations. Commun Biol, 7, 2024
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8OOW
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![BU of 8oow by Molmil](/molmil-images/mine/8oow) | Glutamine synthetase from Methermicoccus shengliensis at a resolution of 2.64 A | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Glutamine synthetase, ... | 著者 | Mueller, M.-C, Lemaire, O.N, Wagner, T. | 登録日 | 2023-04-06 | 公開日 | 2024-01-24 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | 主引用文献 | Differences in regulation mechanisms of glutamine synthetases from methanogenic archaea unveiled by structural investigations. Commun Biol, 7, 2024
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8OOZ
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![BU of 8ooz by Molmil](/molmil-images/mine/8ooz) | Glutamine synthetase from Methermicoccus shengliensis in complex with MgATP at 2.7 A resolution | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, FORMIC ACID, GLYCEROL, ... | 著者 | Mueller, M.-C, Lemaire, O.N, Wagner, T. | 登録日 | 2023-04-06 | 公開日 | 2024-01-24 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Differences in regulation mechanisms of glutamine synthetases from methanogenic archaea unveiled by structural investigations. Commun Biol, 7, 2024
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8PVG
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![BU of 8pvg by Molmil](/molmil-images/mine/8pvg) | Structure of E. coli glutamine synthetase determined by cryoEM at 100 keV | 分子名称: | Glutamine synthetase | 著者 | McMullan, G, Naydenova, K, Mihaylov, D, Peet, M.J, Wilson, H, Yamashita, K, Dickerson, J.L, Chen, S, Cannone, G, Lee, Y, Hutchings, K.A, Gittins, O, Sobhy, M, Wells, T, El-Gomati, M.M, Dalby, J, Meffert, M, Schulze-Briese, C, Henderson, R, Russo, C.J. | 登録日 | 2023-07-17 | 公開日 | 2023-11-29 | 最終更新日 | 2023-12-06 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structure determination by cryoEM at 100 keV. Proc.Natl.Acad.Sci.USA, 120, 2023
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8TFK
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![BU of 8tfk by Molmil](/molmil-images/mine/8tfk) | |
8UFJ
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![BU of 8ufj by Molmil](/molmil-images/mine/8ufj) | Structure of M. mazei GS(R167L-A168G) apo form | 分子名称: | Glutamine synthetase, MAGNESIUM ION | 著者 | Schumacher, M.A. | 登録日 | 2023-10-04 | 公開日 | 2023-11-15 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | M. mazei glutamine synthetase and glutamine synthetase-GlnK1 structures reveal enzyme regulation by oligomer modulation. Nat Commun, 14, 2023
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8TFC
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![BU of 8tfc by Molmil](/molmil-images/mine/8tfc) | |
8TGE
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![BU of 8tge by Molmil](/molmil-images/mine/8tge) | |
8TFB
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![BU of 8tfb by Molmil](/molmil-images/mine/8tfb) | |
7V4K
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![BU of 7v4k by Molmil](/molmil-images/mine/7v4k) | |
7V4J
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![BU of 7v4j by Molmil](/molmil-images/mine/7v4j) | |
7V4I
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![BU of 7v4i by Molmil](/molmil-images/mine/7v4i) | |
7V4L
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![BU of 7v4l by Molmil](/molmil-images/mine/7v4l) | |
7W85
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![BU of 7w85 by Molmil](/molmil-images/mine/7w85) | |
4IS4
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![BU of 4is4 by Molmil](/molmil-images/mine/4is4) | |
4LNF
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![BU of 4lnf by Molmil](/molmil-images/mine/4lnf) | B. subtilis glutamine synthetase structures reveal large active site conformational changes and basis for isoenzyme specific regulation: structure of GS-Q | 分子名称: | GLUTAMINE, Glutamine synthetase, MAGNESIUM ION, ... | 著者 | Schumacher, M.A, Chinnam, N, Tonthat, N, Fisher, S, Wray, L. | 登録日 | 2013-07-11 | 公開日 | 2013-11-13 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.949 Å) | 主引用文献 | Structures of the Bacillus subtilis Glutamine Synthetase Dodecamer Reveal Large Intersubunit Catalytic Conformational Changes Linked to a Unique Feedback Inhibition Mechanism. J.Biol.Chem., 288, 2013
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