PDB: 283 件ウェブページステータス検索Chemie searchBIRD

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4JRR	Crystal structure of disulfide bond oxidoreductase DsbA1 from Legionella pneumophila 分子名称: GLYCEROL, SULFATE ION, Thiol:disulfide interchange protein DsbA 著者 Shumilin, I.A, Jameson-Lee, M, Cymborowski, M, Domagalski, M.J, Chertihin, O, Kpadeh, Z.Z, Yeh, A.J, Hoffman, P.S, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2013-03-21 公開日 2013-04-24 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Crystal structure of disulfide bond oxidoreductase DsbA1 from Legionella pneumophila To be Published
2B3S	structure of the DSBA mutant (P31G-C33A) 分子名称: Thiol:disulfide interchange protein dsbA 著者 Vives, C, Royant, A, Serre, L. 登録日 2005-09-21 公開日 2006-09-05 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Structure of the DSBA mutant (P31G-C33A) To be Published
4K2D	Crystal structure of Burkholderia Pseudomallei DsbA 分子名称: GLYCEROL, Thiol:disulfide interchange protein 著者 McMahon, R.M. 登録日 2013-04-09 公開日 2013-08-14 最終更新日 2014-02-12 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Disarming Burkholderia pseudomallei: Structural and Functional Characterization of a Disulfide Oxidoreductase (DsbA) Required for Virulence In Vivo. Antioxid Redox Signal, 20, 2014
3L9U	Crystal Structure of Salmonella enterica serovar Typhimurium DsbL 分子名称: Disulfide isomerase 著者 Heras, B, Jarrott, R, Shouldice, S.R, Guncar, G. 登録日 2010-01-05 公開日 2010-03-09 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.568 Å) 主引用文献 Structural and functional characterization of three DsbA paralogues from Salmonella enterica serovar typhimurium J.Biol.Chem., 285, 2010
3L9V	Crystal Structure of Salmonella enterica serovar Typhimurium SrgA 分子名称: 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, HEXAETHYLENE GLYCOL, O-ACETALDEHYDYL-HEXAETHYLENE GLYCOL, ... 著者 Heras, B, Jarrott, R, Shouldice, S.R, Guncar, G. 登録日 2010-01-05 公開日 2010-03-09 最終更新日 2017-11-01 実験手法 X-RAY DIFFRACTION (2.151 Å) 主引用文献 Structural and functional characterization of three DsbA paralogues from Salmonella enterica serovar typhimurium J.Biol.Chem., 285, 2010
6XSP	Crystal structure of E.coli DsbA in complex with 2-(2,6-bis(3-methoxyphenyl)benzofuran-3-yl)acetic acid 分子名称: COPPER (II) ION, Thiol:disulfide interchange protein DsbA, [2,6-bis(3-methoxyphenyl)-1-benzofuran-3-yl]acetic acid 著者 Wang, G, Heras, B. 登録日 2020-07-15 公開日 2021-08-11 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Elaboration of a benzofuran scaffold and evaluation of binding affinity and inhibition of Escherichia coli DsbA: A fragment-based drug design approach to novel antivirulence compounds. Bioorg.Med.Chem., 45, 2021
6XSQ	Crystal structure of E.coli DsbA in complex with 2-(6-(3-methoxyphenyl)-2-(4-methoxyphenyl)benzofuran-3-yl)acetic acid 分子名称: COPPER (II) ION, Thiol:disulfide interchange protein DsbA, [6-(3-methoxyphenyl)-2-(4-methoxyphenyl)-1-benzofuran-3-yl]acetic acid 著者 Wang, G, Heras, B. 登録日 2020-07-16 公開日 2021-08-11 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Elaboration of a benzofuran scaffold and evaluation of binding affinity and inhibition of Escherichia coli DsbA: A fragment-based drug design approach to novel antivirulence compounds. Bioorg.Med.Chem., 45, 2021
6XT3	Crystal structure of E.coli DsbA in complex with 3-(3-(carboxymethyl)-6-(3-methoxyphenyl)benzofuran-2-yl)benzoic acid 分子名称: 3-[3-(carboxymethyl)-6-(3-methoxyphenyl)-1-benzofuran-2-yl]benzoic acid, COPPER (II) ION, Thiol:disulfide interchange protein DsbA 著者 Wang, G, Heras, B. 登録日 2020-07-17 公開日 2021-08-11 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Elaboration of a benzofuran scaffold and evaluation of binding affinity and inhibition of Escherichia coli DsbA: A fragment-based drug design approach to novel antivirulence compounds. Bioorg.Med.Chem., 45, 2021
4OCE	Crystal structure of the disulfide oxidoreductase DsbA from Proteus mirabilis 分子名称: MALONATE ION, Thiol:disulfide interchange protein 著者 Kurth, F, Martin, J.L. 登録日 2014-01-09 公開日 2014-05-28 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.768 Å) 主引用文献 Crystal Structure of the Dithiol Oxidase DsbA Enzyme from Proteus Mirabilis Bound Non-covalently to an Active Site Peptide Ligand. J.Biol.Chem., 289, 2014
8U1Y	E.coli DsbA in complex with N-(4-(thiophen-3-yl)benzyl)cyclohexanamine 分子名称: COPPER (II) ION, Thiol:disulfide interchange protein DsbA, ~{N}-[(4-thiophen-3-ylphenyl)methyl]cyclohexanamine 著者 Wang, G, Heras, B. 登録日 2023-09-04 公開日 2024-09-11 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Two-mode inhibition of DsbA: combination of two site-specific inhibitors enhances virulence inhibition in Salmonella enterica serovar Typhimurium To Be Published
8U59	EcDsbA soaked with N-(2-fluorophenyl)-5-methylisoxazole-3-carboxamide and N-(4-(thiophen-3-yl)benzyl)cyclohexanamine 分子名称: COPPER (II) ION, N-(2-fluorophenyl)-5-methyl-1,2-oxazole-3-carboxamide, Thiol:disulfide interchange protein DsbA, ... 著者 Wang, G, Heras, B. 登録日 2023-09-12 公開日 2024-09-25 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Two-mode inhibition of DsbA: combination of two site-specific inhibitors enhances virulence inhibition in Salmonella enterica serovar Typhimurium To Be Published
8UBQ	EcDsbA soaked with N-(2-fluorophenyl)-5-methylisoxazole-3-carboxamide and 2-benzyl-4-phenylthiazole-5-carboxylic acid 分子名称: 2-benzyl-4-phenyl-1,3-thiazole-5-carboxylic acid, COPPER (II) ION, N-(2-fluorophenyl)-5-methyl-1,2-oxazole-3-carboxamide, ... 著者 Wang, G, Heras, B. 登録日 2023-09-24 公開日 2024-09-25 実験手法 X-RAY DIFFRACTION (2.001 Å) 主引用文献 Two-mode inhibition of DsbA: combination of two site-specific inhibitors enhances virulence inhibition in Salmonella enterica serovar Typhimurium To Be Published
3L9S	Crystal Structure of Salmonella enterica serovar Typhimurium DsbA 分子名称: Thiol:disulfide interchange protein 著者 Heras, B, Jarrott, R, Shouldice, S.R, Guncar, G. 登録日 2010-01-05 公開日 2010-03-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Structural and functional characterization of three DsbA paralogues from Salmonella enterica serovar typhimurium J.Biol.Chem., 285, 2010
4OCF	Crystal structure of the disulfide oxidoreductase DsbA (S30XXC33) active site mutant from Proteus mirabilis 分子名称: THIOCYANATE ION, Thiol:disulfide interchange protein 著者 Kurth, F, Martin, J.L. 登録日 2014-01-09 公開日 2014-05-28 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.979 Å) 主引用文献 Crystal Structure of the Dithiol Oxidase DsbA Enzyme from Proteus Mirabilis Bound Non-covalently to an Active Site Peptide Ligand. J.Biol.Chem., 289, 2014
1FVJ	THE 2.06 ANGSTROM STRUCTURE OF THE H32Y MUTANT OF THE DISULFIDE BOND FORMATION PROTEIN (DSBA) 分子名称: DISULFIDE BOND FORMATION PROTEIN 著者 Martin, J.L, Guddat, L.W. 登録日 1996-08-28 公開日 1997-05-15 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 Structural analysis of three His32 mutants of DsbA: support for an electrostatic role of His32 in DsbA stability. Protein Sci., 6, 1997
1FVK	THE 1.7 ANGSTROM STRUCTURE OF WILD TYPE DISULFIDE BOND FORMATION PROTEIN (DSBA) 分子名称: DISULFIDE BOND FORMATION PROTEIN 著者 Martin, J.L, Guddat, L.W. 登録日 1996-08-28 公開日 1997-08-20 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural analysis of three His32 mutants of DsbA: support for an electrostatic role of His32 in DsbA stability. Protein Sci., 6, 1997
4OD7	Complex structure of Proteus mirablis DsbA (C30S) with a non-covalently bound peptide PWATCDS 分子名称: (ACE)PWATCDS(NH2) Peptide, THIOCYANATE ION, Thiol:disulfide interchange protein 著者 Kurth, F, Premkumar, L, Martin, J.L. 登録日 2014-01-10 公開日 2014-05-28 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.597 Å) 主引用文献 Crystal Structure of the Dithiol Oxidase DsbA Enzyme from Proteus Mirabilis Bound Non-covalently to an Active Site Peptide Ligand. J.Biol.Chem., 289, 2014
1DSB	CRYSTAL STRUCTURE OF THE DSBA PROTEIN REQUIRED FOR DISULPHIDE BOND FORMATION IN VIVO 分子名称: DSBA 著者 Martin, J.L, Bardwell, J.C.A, Kuriyan, J. 登録日 1993-05-24 公開日 1994-01-31 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of the DsbA protein required for disulphide bond formation in vivo. Nature, 365, 1993
4WET	Crystal structure of E.Coli DsbA in complex with compound 16 分子名称: 1,2-ETHANEDIOL, N-({4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}carbonyl)-L-tyrosine, SODIUM ION, ... 著者 Ilyichova, O.V, Scanlon, M.J. 登録日 2014-09-11 公開日 2015-01-21 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Application of Fragment-Based Screening to the Design of Inhibitors of Escherichia coli DsbA. Angew.Chem.Int.Ed.Engl., 54, 2015
1R4W	Crystal structure of Mitochondrial class kappa glutathione transferase 分子名称: GLUTATHIONE, Glutathione S-transferase, mitochondrial 著者 Ladner, J.E, Parsons, J.F, Rife, C.L, Gilliland, G.L, Armstrong, R.N. 登録日 2003-10-08 公開日 2004-02-03 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Parallel Evolutionary Pathways for Glutathione Transferases: Structure and Mechanism of the Mitochondrial Class Kappa Enzyme rGSTK1-1 Biochemistry, 43, 2004
4WF5	Crystal structure of E.Coli DsbA soaked with compound 4 分子名称: 1,2-ETHANEDIOL, 4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxylic acid, COPPER (II) ION, ... 著者 Adams, L.A, Sharma, P, Mohanty, B, Ilyichova, O.V, Mulcair, M.D, Williams, M.L, Gleeson, E.C, Totsika, M, Doak, B.C, Caria, S, Rimmer, K, Shouldice, S.R, Vazirani, M, Headey, S.J, Plumb, B.R, Martin, J.L, Heras, B, Simpson, J.S, Scanlon, M.J. 登録日 2014-09-12 公開日 2015-01-21 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Application of Fragment-Based Screening to the Design of Inhibitors of Escherichia coli DsbA. Angew.Chem.Int.Ed.Engl., 54, 2015
4WEY	Crystal structure of E.Coli DsbA in complex with compound 17 分子名称: 1,2-ETHANEDIOL, N-({4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}carbonyl)-L-serine, Thiol:disulfide interchange protein 著者 Adams, L.A, Sharma, P, Mohanty, B, Ilyichova, O.V, Mulcair, M.D, Williams, M.L, Gleeson, E.C, Totsika, M, Doak, B.C, Caria, S, Rimmer, K, Shouldice, S.R, Vazirani, M, Headey, S.J, Plumb, B.R, Martin, J.L, Heras, B, Simpson, J.S, Scanlon, M.J. 登録日 2014-09-11 公開日 2015-01-21 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Application of Fragment-Based Screening to the Design of Inhibitors of Escherichia coli DsbA. Angew.Chem.Int.Ed.Engl., 54, 2015
4WF4	Crystal structure of E.Coli DsbA co-crystallised in complex with compound 4 分子名称: 1,2-ETHANEDIOL, 4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxylic acid, Thiol:disulfide interchange protein 著者 Adams, L.A, Sharma, P, Mohanty, B, Ilyichova, O.V, Mulcair, M.D, Williams, M.L, Gleeson, E.C, Totsika, M, Doak, B.C, Caria, S, Rimmer, K, Shouldice, S.R, Vazirani, M, Headey, S.J, Plumb, B.R, Martin, J.L, Heras, B, Simpson, J.S, Scanlon, M.J. 登録日 2014-09-12 公開日 2015-01-21 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Application of Fragment-Based Screening to the Design of Inhibitors of Escherichia coli DsbA. Angew.Chem.Int.Ed.Engl., 54, 2015
2MBT	NMR study of PaDsbA 分子名称: Thiol:disulfide interchange protein DsbA 著者 Rimmer, K, Mohanty, B, Scanlon, M.J. 登録日 2013-08-03 公開日 2014-11-12 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Fragment library screening identifies hits that bind to the non-catalytic surface of Pseudomonas aeruginosa DsbA1. PLoS ONE, 12, 2017
3DKS	DsbA substrate complex 分子名称: Thiol:disulfide interchange protein dsbA, siga peptide 著者 Paxman, J.J, Borg, N.A, Horne, J, Rossjohn, J, Thompson, P.E, Piek, S, Kahler, C.M, Sakellaris, H, Scanlon, M.J. 登録日 2008-06-25 公開日 2009-05-12 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The structure of the bacterial oxidoreductase enzyme DsbA in complex with a peptide reveals a basis for substrate specificity in the catalytic cycle of DsbA enzymes J.Biol.Chem., 284, 2009

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