PDB: 38 件ウェブページステータス検索Chemie searchBIRD

---

1E2K	Kinetics and crystal structure of the wild-type and the engineered Y101F mutant of Herpes simplex virus type 1 thymidine kinase interacting with (North)-methanocarba-thymidine 分子名称: 1-[4-HYDROXY-5-(HYDROXYMETHYL)BICYCLO[3.1.0]HEX-2-YL]-5-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE, SULFATE ION, THYMIDINE KINASE 著者 Vogt, J, Scapozza, L, Schulz, G.E. 登録日 2000-05-23 公開日 2000-08-19 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Kinetics and Crystal Structure of the Wild-Type and the Engineered Y101F Mutant of Herpes Simplex Virus Type 1 Thymidine Kinase Interacting with (North)-Methanocarba-Thymidine Biochemistry, 39, 2000
1E2J	The nucleoside binding site of Herpes simplex type 1 thymidine kinase analyzed by X-ray crystallography 分子名称: SULFATE ION, THYMIDINE, THYMIDINE KINASE 著者 Vogt, J, Scapozza, L, Schulz, G.E. 登録日 2000-05-23 公開日 2000-11-06 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Nucleoside Binding Site of Herpes Simplex Type 1 Thymidine Kinase Analyzed by X-Ray Crystallography Proteins: Struct.,Funct., Genet., 41, 2000
1E2H	The nucleoside binding site of Herpes simplex type 1 thymidine kinase analyzed by X-ray crystallography 分子名称: SULFATE ION, THYMIDINE KINASE 著者 Vogt, J, Scapozza, L, Schulz, G.E. 登録日 2000-05-23 公開日 2000-11-06 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Nucleoside Binding Site of Herpes Simplex Type 1 Thymidine Kinase Analyzed by X-Ray Crystallography Proteins: Struct.,Funct., Genet., 41, 2000
1E2N	HPT + HMTT 分子名称: 6-{[4-(HYDROXYMETHYL)-5-METHYL-2,6-DIOXOHEXAHYDROPYRIMIDIN-5-YL]METHYL}-5-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE, SULFATE ION, THYMIDINE KINASE 著者 Vogt, J, Scapozza, L, Schulz, G.E. 登録日 2000-05-23 公開日 2001-03-31 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The Effect of Substrate Binding on the Conformation and Structural Stability of Herpes Simplex Virus Type 1 Thymidine Kinase Protein Sci., 10, 2001
1E2P	Thymidine kinase, DHBT 分子名称: 6-[3-HYDROXY-2-(HYDROXYMETHYL)PROPYL]-5-METHYL-2,4(1H,3H)-PYRIMIDINEDIONE, SULFATE ION, THYMIDINE KINASE 著者 Schulz, G.E, Kessler, U. 登録日 2000-05-23 公開日 2001-04-26 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The Effect of Substrate Binding on the Conformation and Structural Stability of Herpes Simplex Virus Type 1 Thymidine Kinase Protein Sci., 10, 2001
1P73	Crystal structure of EHV4-TK complexed with TP4A 分子名称: P1-(5'-ADENOSYL)P4-(5'-(2'-DEOXY-THYMIDYL))TETRAPHOSPHATE, SULFATE ION, Thymidine kinase 著者 Gardberg, A, Shuvalova, L, Monnerjahn, C, Konrad, M, Lavie, A. 登録日 2003-04-30 公開日 2003-11-04 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis for the dual thymidine and thymidylate kinase activity of herpes thymidine kinases. Structure, 11, 2003
1P72	Crystal structure of EHV4-TK complexed with Thy and ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, SULFATE ION, THYMIDINE, ... 著者 Gardberg, A, Shuvalova, L, Monnerjahn, C, Konrad, M, Lavie, A. 登録日 2003-04-30 公開日 2003-11-04 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural basis for the dual thymidine and thymidylate kinase activity of herpes thymidine kinases. Structure, 11, 2003
1P75	Crystal structure of EHV4-TK complexed with TP5A 分子名称: P1-(5'-ADENOSYL)P5-(5'-THYMIDYL)PENTAPHOSPHATE, SULFATE ION, Thymidine kinase 著者 Gardberg, A, Shuvalova, L, Monnerjahn, C, Konrad, M, Lavie, A. 登録日 2003-04-30 公開日 2003-11-04 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (3.02 Å) 主引用文献 Structural basis for the dual thymidine and thymidylate kinase activity of herpes thymidine kinases. Structure, 11, 2003
1P7C	Crystal Structure of HSV1-TK complexed with TP5A 分子名称: P1-(5'-ADENOSYL)P5-(5'-THYMIDYL)PENTAPHOSPHATE, SULFATE ION, THYMIDINE, ... 著者 Gardberg, A, Shuvalova, L, Monnerjahn, C, Konrad, M, Lavie, A. 登録日 2003-05-01 公開日 2003-11-04 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural basis for the dual thymidine and thymidylate kinase activity of herpes thymidine kinases. Structure, 11, 2003
1OSN	Crystal structure of Varicella zoster virus thymidine kinase in complex with BVDU-MP and ADP 分子名称: (E)-5-(2-BROMOVINYL)-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, Thymidine kinase 著者 Bird, L.E, Ren, J, Wright, A, Leslie, K.D, Degreve, B, Balzarini, J, Stammers, D.K. 登録日 2003-03-20 公開日 2003-06-10 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Crystal structure of varicella zoster virus thymidine kinase J.Biol.Chem., 278, 2003
1E2L	Kinetics and crystal structure of the wild-type and the engineered Y101F mutant of Herpes simplex virus type 1 thymidine kinase interacting with (North)-methanocarba-thymidine 分子名称: 1-[4-HYDROXY-5-(HYDROXYMETHYL)BICYCLO[3.1.0]HEX-2-YL]-5-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE, SULFATE ION, THYMIDINE KINASE 著者 Vogt, J, Scapozza, L, Schulz, G.E. 登録日 2000-05-23 公開日 2000-08-18 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Kinetics and Crystal Structure of the Wild-Type and the Engineered Y101F Mutant of Herpes Simplex Virus Type 1 Thymidine Kinase Interacting with (North)-Methanocarba-Thymidine Biochemistry, 39, 2000
1E2M	HPT + HMTT 分子名称: 6-HYDROXYPROPYLTHYMINE, SULFATE ION, THYMIDINE KINASE 著者 Vogt, J, Scapozza, L, Schulz, G.E. 登録日 2000-05-23 公開日 2001-03-31 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The Effect of Substrate Binding on the Conformation and Structural Stability of Herpes Simplex Virus Type 1 Thymidine Kinase Protein Sci., 10, 2001
1QHI	HERPES SIMPLEX VIRUS TYPE-I THYMIDINE KINASE COMPLEXED WITH A NOVEL NON-SUBSTRATE INHIBITOR, 9-(4-HYDROXYBUTYL)-N2-PHENYLGUANINE 分子名称: 9-(4-HYDROXYBUTYL)-N2-PHENYLGUANINE, PROTEIN (THYMIDINE KINASE), SULFATE ION 著者 Bennett, M.S, Wien, F, Champness, J.N, Batuwangala, T, Rutherford, T, Summers, W.C, Sun, H, Wright, G, Sanderson, M.R. 登録日 1999-05-12 公開日 1999-07-09 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure to 1.9 A resolution of a complex with herpes simplex virus type-1 thymidine kinase of a novel, non-substrate inhibitor: X-ray crystallographic comparison with binding of aciclovir. FEBS Lett., 443, 1999

<12