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3M5B
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BU of 3m5b by Molmil
Crystal structure of the BTB domain from FAZF/ZBTB32
分子名称: Zinc finger and BTB domain-containing protein 32
著者Stogios, P.J, Pomroy, N.C, Prive, G.G.
登録日2010-03-12
公開日2010-06-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Insights into Strand Exchange in BTB Domain Dimers from the Crystal Structures of FAZF and Miz1.
J.Mol.Biol., 400, 2010
3M52
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BU of 3m52 by Molmil
Crystal structure of the BTB domain from the Miz-1/ZBTB17 transcription regulator
分子名称: ACETATE ION, ZINC ION, Zinc finger and BTB domain-containing protein 17
著者Stogios, P.J, Cuesta-Seijo, J.A, Chen, L, Prive, G.G.
登録日2010-03-12
公開日2010-06-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Insights into Strand Exchange in BTB Domain Dimers from the Crystal Structures of FAZF and Miz1.
J.Mol.Biol., 400, 2010
3M8V
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BU of 3m8v by Molmil
Crystal structure of the BTB domain from Kaiso/ZBTB33, form II
分子名称: Transcriptional regulator Kaiso
著者Nielsen, T.K, Stogios, P.J, Prive, G.G.
登録日2010-03-19
公開日2011-03-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of the BTB domain from Kaiso/ZBTB33, form II
TO BE PUBLISHED
3M4T
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BU of 3m4t by Molmil
Crystal structure of the BTB domain from Kaiso/ZBTB33, form I
分子名称: SULFATE ION, Transcriptional regulator Kaiso
著者Stogios, P.J, Chen, L, Prive, G.G.
登録日2010-03-11
公開日2011-04-27
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal structure of the BTB domain from Kaiso/ZBTB33, form I
TO BE PUBLISHED
3OHU
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BU of 3ohu by Molmil
Crystal structure of the human Bach2 POZ domain, form I
分子名称: Transcription regulator protein BACH2
著者Rosbrook, G.O, Stead, M.A, Carr, S.B, Wright, S.C.
登録日2010-08-18
公開日2011-11-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The structure of the Bach2 POZ-domain dimer reveals an intersubunit disulfide bond.
Acta Crystallogr.,Sect.D, 68, 2012
3OHV
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Crystal structure of the human Bach2 POZ domain, form II
分子名称: Transcription regulator protein BACH2
著者Rosbrook, G.O, Stead, M.A, Carr, S.B, Wright, S.C.
登録日2010-08-18
公開日2011-11-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The structure of the Bach2 POZ-domain dimer reveals an intersubunit disulfide bond.
Acta Crystallogr.,Sect.D, 68, 2012
4APF
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BU of 4apf by Molmil
Crystal structure of the human KLHL11-Cul3 complex at 3.1A resolution
分子名称: CULLIN 3, KELCH-LIKE PROTEIN 11
著者Canning, P, Cooper, C.D.O, Krojer, T, Vollmar, M, Ugochukwu, E, Muniz, J.R.C, Ayinampudi, V, Savitsky, P, Arrowsmith, C.H, Edwards, A.M, Bountra, C, von Delft, F, Bullock, A.N, Structural Genomics Consortium (SGC)
登録日2012-04-02
公開日2012-05-09
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural Basis for Cul3 Assembly with the Btb-Kelch Family of E3 Ubiquitin Ligases.
J.Biol.Chem., 288, 2013
4AP2
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Crystal structure of the human KLHL11-Cul3 complex at 2.8A resolution
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, CULLIN-3, ...
著者Canning, P, Cooper, C.D.O, Krojer, T, Filippakopoulos, P, Ayinampudi, V, Arrowsmith, C.H, Edwards, A.M, Bountra, C, von Delft, F, Bullock, A.N, Structural Genomics Consortium (SGC)
登録日2012-03-30
公開日2012-05-09
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Basis for Cul3 Assembly with the Btb-Kelch Family of E3 Ubiquitin Ligases.
J.Biol.Chem., 288, 2013
4EOZ
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Crystal structure of the SPOP BTB domain complexed with the Cul3 N-terminal domain
分子名称: Cullin-3, Speckle-type POZ protein
著者Prive, G.G, Errington, W.J.
登録日2012-04-16
公開日2012-05-30
最終更新日2013-01-09
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Adaptor protein self-assembly drives the control of a cullin-RING ubiquitin ligase.
Structure, 20, 2012
4HXI
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BU of 4hxi by Molmil
Crystal structure of KLHL3/Cul3 complex
分子名称: Cullin-3, Kelch-like protein 3
著者Ji, A.X, Prive, G.G.
登録日2012-11-10
公開日2013-03-13
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.513 Å)
主引用文献Crystal structure of KLHL3 in complex with Cullin3.
Plos One, 8, 2013
4J8Z
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Crystal Structure of the Human SPOP BTB Domain
分子名称: Speckle-type POZ protein
著者Stead, M.A, Wright, S.C.
登録日2013-02-15
公開日2013-09-11
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Structural basis of high-order oligomerization of the cullin-3 adaptor SPOP
Acta Crystallogr.,Sect.D, 69, 2013
4CP3
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BU of 4cp3 by Molmil
The structure of BCL6 BTB (POZ) domain in complex with the ansamycin antibiotic rifabutin.
分子名称: B-CELL LYMPHOMA 6 PROTEIN, RIFABUTIN
著者Evans, S.E, Fairall, L, Goult, B.T, Jamieson, A.G, Ferrigno, P.K, Ford, R, Wagner, S.D, Schwabe, J.W.R.
登録日2014-01-31
公開日2014-03-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Ansamycin Antibiotic, Rifamycin Sv, Inhibits Bcl6 Transcriptional Repression and Forms a Complex with the Bcl6-Btb/Poz Domain.
Plos One, 9, 2014
4CXI
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BTB domain of KEAP1
分子名称: KELCH-LIKE ECH-ASSOCIATED PROTEIN 1
著者Cleasby, A, Yon, J, Day, P.J, Richardson, C, Tickle, I.J, Williams, P.A, Callahan, J.F, Carr, R, Concha, N, Kerns, J.K, Qi, H, Sweitzer, T, Ward, P, Davies, T.G.
登録日2014-04-07
公開日2014-06-18
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structure of the Btb Domain of Keap1 and its Interaction with the Triterpenoid Antagonist Cddo.
Plos One, 9, 2014
4CXJ
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BTB domain of KEAP1 C151W mutant
分子名称: KELCH-LIKE ECH-ASSOCIATED PROTEIN 1
著者Cleasby, A, Yon, J, Day, P.J, Richardson, C, Tickle, I.J, Williams, P.A, Callahan, J.F, Carr, R, Concha, N, Kerns, J.K, Qi, H, Sweitzer, T, Ward, P, Davies, T.G.
登録日2014-04-07
公開日2014-06-18
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of the Btb Domain of Keap1 and its Interaction with the Triterpenoid Antagonist Cddo.
Plos One, 9, 2014
4CXT
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BU of 4cxt by Molmil
BTB domain of KEAP1 in complex with CDDO
分子名称: (13alpha,18alpha)-2-cyano-3-hydroxy-12-oxooleana-2,9(11)-dien-28-oic acid, KELCH-LIKE ECH-ASSOCIATED PROTEIN 1
著者Cleasby, A, Yon, J, Day, P.J, Richardson, C, Tickle, I.J, Williams, P.A, Callahan, J.F, Carr, R, Concha, N, Kerns, J.K, Qi, H, Sweitzer, T, Ward, P, Davies, T.G.
登録日2014-04-08
公開日2014-06-18
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献Structure of the Btb Domain of Keap1 and its Interaction with the Triterpenoid Antagonist Cddo.
Plos One, 9, 2014
4U77
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BTB domain from Drosophila CP190
分子名称: Centrosome-associated zinc finger protein CP190, DIMETHYL SULFOXIDE, GLYCEROL
著者Allemand, F, Cohen-Gonsaud, M, Labesse, G, Nollmann, M.
登録日2014-07-30
公開日2014-08-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Chromatin Insulator Factors Involved in Long-Range DNA Interactions and Their Role in the Folding of the Drosophila Genome.
Plos Genet., 10, 2014
4UYI
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BU of 4uyi by Molmil
Crystal structure of the BTB domain of human SLX4 (BTBD12)
分子名称: STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT SLX4
著者Pinkas, D.M, Sanvitale, C.E, Strain-Damerell, C, Fairhead, M, Wang, D, Tallant, C, Cooper, C.D.O, Sorrell, F.J, Kopec, J, Chaikuad, A, Fitzpatrick, F, Pike, A.C.W, Hozjan, V, Ying, Z, Roos, A.K, Savitsky, P, Bradley, A, Nowak, R, Filippakopoulos, P, Krojer, T, Burgess-Brown, N.A, Marsden, B.D, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.
登録日2014-09-01
公開日2014-10-01
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Crystal Structure of the Btb Domain of Human Slx4 (Btbd12)
To be Published
4U2N
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Crystal structure of a complex of the Miz1- and Nac1 POZ domains.
分子名称: Zinc finger and BTB domain-containing protein 17,Nucleus accumbens-associated protein 1
著者Stead, M.A, Wright, S.C.
登録日2014-07-17
公開日2014-12-10
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structures of heterodimeric POZ domains of Miz1/BCL6 and Miz1/NAC1.
Acta Crystallogr.,Sect.F, 70, 2014
4U2M
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Crystal structure of a complex of the Miz1- and BCL6 POZ domains.
分子名称: Zinc finger and BTB domain-containing protein 17,B-cell lymphoma 6 protein
著者Stead, M.A, Wright, S.C.
登録日2014-07-17
公開日2014-12-10
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Structures of heterodimeric POZ domains of Miz1/BCL6 and Miz1/NAC1.
Acta Crystallogr.,Sect.F, 70, 2014
5EUP
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BU of 5eup by Molmil
Structure of the Drosophila melanogaster CP190 BTB domain
分子名称: Centrosome-associated zinc finger protein CP190
著者Plevock, K.M, Galletta, B.J, Slep, K.C, Rusan, N.M.
登録日2015-11-19
公開日2015-12-23
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Newly Characterized Region of CP190 Associates with Microtubules and Mediates Proper Spindle Morphology in Drosophila Stem Cells.
Plos One, 10, 2015
4ZOU
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Crystal structure of the BTB domain of SLX4
分子名称: Structure-specific endonuclease subunit SLX4
著者Wan, B, Chen, Y, Wu, J, Liu, Y, Lei, M.
登録日2015-05-07
公開日2016-05-04
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The BTB domain is both a structural and functional pivot of the SLX4-nuclease complex
to be published
5DAF
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BU of 5daf by Molmil
Crystal Structure of Human KEAP1 BTB Domain in Complex with Small Molecule TX64063
分子名称: (5aS,6S,9aS)-7-hydroxy-2,6,9a-trimethyl-3-(pyridin-3-yl)-4,5,5a,6,9,9a-hexahydro-2H-benzo[g]indazole-8-carbonitrile, Kelch-like ECH-associated protein 1
著者Huerta, C, Jiang, X, Trevino, I, Bender, C.F, Swinger, K.K, Stoll, V.S, Ferguson, D.A, Thomas, P.J, Probst, B, Dulubova, I, Visnick, M, Wigley, W.C.
登録日2015-08-19
公開日2016-08-10
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Characterization of novel small-molecule NRF2 activators: Structural and biochemical validation of stereospecific KEAP1 binding.
Biochim.Biophys.Acta, 1860, 2016
5DAD
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BU of 5dad by Molmil
Crystal Structure of Human KEAP1 BTB Domain in Complex with Small Molecule TX64014
分子名称: (6aS,7S,10aS)-8-hydroxy-4-methoxy-2,7,10a-trimethyl-5,6,6a,7,10,10a-hexahydrobenzo[h]quinazoline-9-carbonitrile, Kelch-like ECH-associated protein 1
著者Huerta, C, Jiang, X, Trevino, I, Bender, C.F, Swinger, K.K, Stoll, V.S, Ferguson, D.A, Thomas, P.J, Probst, B, Dulubova, I, Visnick, M, Wigley, W.C.
登録日2015-08-19
公開日2016-08-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Characterization of novel small-molecule NRF2 activators: Structural and biochemical validation of stereospecific KEAP1 binding.
Biochim.Biophys.Acta, 1860, 2016
5H7G
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Crystal structure of the BCL6 BTB domain in complex with F1324
分子名称: B-cell lymphoma 6 protein, F1324 peptide, SULFATE ION
著者Sogabe, S, Ida, K, Lane, W, Snell, G.
登録日2016-11-18
公開日2016-12-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Discovery of high-affinity BCL6-binding peptide and its structure-activity relationship.
Biochem. Biophys. Res. Commun., 482, 2017
5H7H
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Crystal structure of the BCL6 BTB domain in complex with F1324(10-13)
分子名称: 1,2-ETHANEDIOL, B-cell lymphoma 6 protein, F1324 peptide residues 10-13
著者Sogabe, S, Ida, K, Lane, W, Snell, G.
登録日2016-11-18
公開日2016-12-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Discovery of high-affinity BCL6-binding peptide and its structure-activity relationship.
Biochem. Biophys. Res. Commun., 482, 2017

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