7EFJ
 
 | | Crystal Structure Analysis of human PIN1 | | 分子名称: | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, 8-(2-chloroacetyl)-4-(furan-2-ylmethyl)-1-thia-4,8-diazaspiro[4.5]decan-3-one, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | | 著者 | Liu, L, Li, J. | | 登録日 | 2021-03-21 | | 公開日 | 2022-02-16 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.992 Å) | | 主引用文献 | Computational and Structure-Based Development of High Potent Cell-Active Covalent Inhibitor Targeting the Peptidyl-Prolyl Isomerase NIMA-Interacting-1 (Pin1).
J.Med.Chem., 65, 2022
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7BQG
 | | Complex structure of SAV1 and Dendrin | | 分子名称: | POTASSIUM ION, Protein salvador homolog 1,Dendrin | | 著者 | Lin, Z, Zhang, M. | | 登録日 | 2020-03-24 | | 公開日 | 2020-09-23 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.55010867 Å) | | 主引用文献 | A WW Tandem-Mediated Dimerization Mode of SAV1 Essential for Hippo Signaling.
Cell Rep, 32, 2020
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7BQF
 | | Dimerization of SAV1 WW tandem | | 分子名称: | 1,4-DIETHYLENE DIOXIDE, Protein salvador homolog 1 | | 著者 | Lin, Z, Zhang, M. | | 登録日 | 2020-03-24 | | 公開日 | 2020-09-23 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.70037615 Å) | | 主引用文献 | A WW Tandem-Mediated Dimerization Mode of SAV1 Essential for Hippo Signaling.
Cell Rep, 32, 2020
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7ABG
 | | Human pre-Bact-1 spliceosome | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, Cell division cycle 5-like protein, ... | | 著者 | Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. | | 登録日 | 2020-09-07 | | 公開日 | 2020-12-23 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (7.8 Å) | | 主引用文献 | Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation.
Science, 370, 2020
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7ABF
 | | Human pre-Bact-1 spliceosome core structure | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | | 著者 | Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. | | 登録日 | 2020-09-07 | | 公開日 | 2020-12-09 | | 最終更新日 | 2020-12-30 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation.
Science, 370, 2020
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6VAJ
 | | Crystal Structure Analysis of human PIN1 | | 分子名称: | 2-chloro-N-(2,2-dimethylpropyl)-N-[(3R)-1,1-dioxo-1lambda~6~-thiolan-3-yl]acetamide, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, SULFATE ION, ... | | 著者 | Seo, H.-S, Dhe-Paganon, S. | | 登録日 | 2019-12-17 | | 公開日 | 2020-12-30 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | | 主引用文献 | Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo.
Nat.Chem.Biol., 17, 2021
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6SVH
 | | Protein allostery of the WW domain at atomic resolution: FFpSPR bound structure | | 分子名称: | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | | 著者 | Strotz, D, Orts, J, Friedmann, M, Guntert, P, Vogeli, B, Riek, R. | | 登録日 | 2019-09-18 | | 公開日 | 2020-09-30 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Protein Allostery at Atomic Resolution.
Angew.Chem.Int.Ed.Engl., 59, 2020
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6SVE
 | | Protein allostery of the WW domain at atomic resolution: pCdc25C bound structure | | 分子名称: | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | | 著者 | Strotz, D, Orts, J, Friedmann, M, Guntert, P, Vogeli, B, Riek, R. | | 登録日 | 2019-09-18 | | 公開日 | 2020-10-07 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Protein Allostery at Atomic Resolution.
Angew.Chem.Int.Ed.Engl., 59, 2020
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6SVC
 | | Protein allostery of the WW domain at atomic resolution: apo structure | | 分子名称: | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | | 著者 | Strotz, D, Orts, J, Friedmann, M, Guntert, P, Vogeli, B, Riek, R. | | 登録日 | 2019-09-18 | | 公開日 | 2020-09-30 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Protein Allostery at Atomic Resolution.
Angew.Chem.Int.Ed.Engl., 59, 2020
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6RSS
 | | Solution structure of the fourth WW domain of WWP2 with GB1-tag | | 分子名称: | NEDD4-like E3 ubiquitin-protein ligase WWP2 | | 著者 | Wahl, L.C, Watt, J.E, Tolchard, J, Blumenschein, T.M.A, Chantry, A. | | 登録日 | 2019-05-22 | | 公開日 | 2019-10-09 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Smad7 Binds Differently to Individual and Tandem WW3 and WW4 Domains of WWP2 Ubiquitin Ligase Isoforms.
Int J Mol Sci, 20, 2019
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6PX3
 | | Set2 bound to nucleosome | | 分子名称: | DNA (145-MER), Histone H2B 1.1, Histone H3, ... | | 著者 | Halic, M, Bilokapic, S. | | 登録日 | 2019-07-24 | | 公開日 | 2019-08-28 | | 最終更新日 | 2019-09-04 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Nucleosome and ubiquitin position Set2 to methylate H3K36.
Nat Commun, 10, 2019
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6O34
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6O33
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6NZO
 | | Set2 bound to nucleosome | | 分子名称: | DNA (149-MER), Histone H2B 1.1, Histone H3, ... | | 著者 | Halic, M, Bilokapic, S. | | 登録日 | 2019-02-14 | | 公開日 | 2019-08-28 | | 最終更新日 | 2019-09-04 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Nucleosome and ubiquitin position Set2 to methylate H3K36.
Nat Commun, 10, 2019
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6N7P
 | | S. cerevisiae spliceosomal E complex (UBC4) | | 分子名称: | 56 kDa U1 small nuclear ribonucleoprotein component, Nuclear cap-binding protein complex subunit 1, Nuclear cap-binding protein subunit 2, ... | | 著者 | Liu, S, Li, X, Zhou, Z.H, Zhao, R. | | 登録日 | 2018-11-27 | | 公開日 | 2019-09-18 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | A unified mechanism for intron and exon definition and back-splicing.
Nature, 573, 2019
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6KKG
 | | Crystal structure of MAGI2-Dendrin complex | | 分子名称: | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2, Peptide from Dendrin | | 著者 | Zhu, J.W, Zhang, H.J, Lin, L, Zhang, R.G. | | 登録日 | 2019-07-25 | | 公開日 | 2020-07-29 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Phase separation of MAGI2-mediated complex underlies formation of slit diaphragm complex in glomerular filtration barrier
To Be Published
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6JK1
 | | Crystal Structure of YAP1 and Dendrin complex 2 | | 分子名称: | Dendrin,Transcriptional coactivator YAP1 | | 著者 | Lin, Z, Yang, Z, Ji, Z, Zhang, M. | | 登録日 | 2019-02-27 | | 公開日 | 2019-09-25 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Decoding WW domain tandem-mediated target recognitions in tissue growth and cell polarity.
Elife, 8, 2019
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6JK0
 | | Crystal Structure of YAP1 and Dendrin complex | | 分子名称: | CALCIUM ION, Transcriptional coactivator YAP1,Dendrin | | 著者 | Lin, Z, Yang, Z, Ji, Z, Zhang, M. | | 登録日 | 2019-02-27 | | 公開日 | 2019-09-25 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Decoding WW domain tandem-mediated target recognitions in tissue growth and cell polarity.
Elife, 8, 2019
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6JJZ
 | | Crystal Structure of MAGI2 and Dendrin complex | | 分子名称: | ACETATE ION, Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2, ... | | 著者 | Lin, Z, Zhang, H, Yang, Z, Ji, Z, Zhang, M, Zhu, J. | | 登録日 | 2019-02-27 | | 公開日 | 2019-09-25 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Decoding WW domain tandem-mediated target recognitions in tissue growth and cell polarity.
Elife, 8, 2019
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6JJY
 | | Crystal Structure of KIBRA and beta-Dystroglycan | | 分子名称: | Peptide from Dystroglycan, Protein KIBRA, SULFATE ION | | 著者 | Lin, Z, Yang, Z, Ji, Z, Zhang, M. | | 登録日 | 2019-02-27 | | 公開日 | 2019-09-25 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.298 Å) | | 主引用文献 | Decoding WW domain tandem-mediated target recognitions in tissue growth and cell polarity.
Elife, 8, 2019
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6JJX
 | | Crystal Structure of KIBRA and Angiomotin complex | | 分子名称: | Peptide from Angiomotin, Protein KIBRA | | 著者 | Lin, Z, Yang, Z, Ji, Z, Zhang, M. | | 登録日 | 2019-02-27 | | 公開日 | 2019-09-25 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Decoding WW domain tandem-mediated target recognitions in tissue growth and cell polarity.
Elife, 8, 2019
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6JJW
 | | Crystal Structure of KIBRA and PTPN14 complex | | 分子名称: | CHLORIDE ION, FORMIC ACID, GLYCEROL, ... | | 著者 | Lin, Z, Yang, Z, Ji, Z, Zhang, M. | | 登録日 | 2019-02-27 | | 公開日 | 2019-09-25 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Decoding WW domain tandem-mediated target recognitions in tissue growth and cell polarity.
Elife, 8, 2019
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6J69
 | | Structure of KIBRA and Dendrin Complex | | 分子名称: | Peptide from Dendrin, Protein KIBRA | | 著者 | Lin, Z, Yang, Z, Ji, Z, Zhang, M. | | 登録日 | 2019-01-14 | | 公開日 | 2019-03-20 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.753 Å) | | 主引用文献 | Kibra Modulates Learning and Memory via Binding to Dendrin.
Cell Rep, 26, 2019
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6J68
 | | Structure of KIBRA and LATS1 Complex | | 分子名称: | Peptide from Serine/threonine-protein kinase LATS1, Protein KIBRA | | 著者 | Lin, Z, Yang, Z, Ji, Z, Zhang, M. | | 登録日 | 2019-01-14 | | 公開日 | 2019-09-25 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.495 Å) | | 主引用文献 | Decoding WW domain tandem-mediated target recognitions in tissue growth and cell polarity.
Elife, 8, 2019
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6J1Z
 | | WWP2 semi-open conformation | | 分子名称: | NEDD4-like E3 ubiquitin-protein ligase WWP2 | | 著者 | Liu, Z.H. | | 登録日 | 2018-12-30 | | 公開日 | 2019-07-24 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | A multi-lock inhibitory mechanism for fine-tuning enzyme activities of the HECT family E3 ligases.
Nat Commun, 10, 2019
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