8OJ8
 
 | | 60S ribosomal subunit bound to the E3-UFM1 complex - state 1 (native) | | 分子名称: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | | 著者 | Penchev, I, DaRosa, P.A, Becker, T, Beckmann, R, Kopito, R. | | 登録日 | 2023-03-24 | | 公開日 | 2024-02-21 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | UFM1 E3 ligase promotes recycling of 60S ribosomal subunits from the ER.
Nature, 627, 2024
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8OJ0
 | | 60S ribosomal subunit bound to the E3-UFM1 complex - state 2 (native) | | 分子名称: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | | 著者 | Penchev, I, DaRosa, P.A, Becker, T, Beckmann, R, Kopito, R. | | 登録日 | 2023-03-23 | | 公開日 | 2024-02-21 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | UFM1 E3 ligase promotes recycling of 60S ribosomal subunits from the ER.
Nature, 627, 2024
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7XHB
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5GAE
 | | RNC in complex with a translocating SecYEG | | 分子名称: | 23S rRNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ... | | 著者 | Jomaa, A, Boehringer, D, Leibundgut, M, Ban, N. | | 登録日 | 2015-11-25 | | 公開日 | 2016-01-27 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3.33 Å) | | 主引用文献 | Structures of the E. coli translating ribosome with SRP and its receptor and with the translocon.
Nat Commun, 7, 2016
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7XHA
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8DNW
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6ITC
 | | Structure of a substrate engaged SecA-SecY protein translocation machine | | 分子名称: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ... | | 著者 | Ma, C.Y, Wu, X.F, Sun, D.J, Park, E.Y, Rapoport, T.A, Gao, N, Long, L. | | 登録日 | 2018-11-21 | | 公開日 | 2019-06-12 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | | 主引用文献 | Structure of the substrate-engaged SecA-SecY protein translocation machine.
Nat Commun, 10, 2019
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2YXQ
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8BTK
 | | Structure of the TRAP complex with the Sec translocon and a translating ribosome | | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | | 著者 | Jaskolowski, M, Jomaa, A, Gamerdinger, M, Shrestha, S, Leibundgut, M, Deuerling, E, Ban, N. | | 登録日 | 2022-11-29 | | 公開日 | 2023-05-24 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Molecular basis of the TRAP complex function in ER protein biogenesis.
Nat.Struct.Mol.Biol., 30, 2023
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1RHZ
 | | The structure of a protein conducting channel | | 分子名称: | Preprotein translocase secE subunit, Preprotein translocase secY subunit, SecBeta | | 著者 | van den Berg, B, Clemons Jr, W.M, Collinson, I, Modis, Y, Hartmann, E, Harrison, S.C, Rapoport, T.A. | | 登録日 | 2003-11-15 | | 公開日 | 2004-01-06 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | X-ray structure of a protein-conducting channel.
Nature, 427, 2004
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2YXR
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3JC2
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5CH4
 | | Peptide-Bound State of Thermus thermophilus SecYEG | | 分子名称: | Protein translocase subunit SecE, Protein translocase subunit SecY, Putative preprotein translocase, ... | | 著者 | Tanaka, Y, Sugano, Y, Takemoto, M, Kusakizako, T, Kumazaki, K, Ishitani, R, Nureki, O, Tsukazaki, T. | | 登録日 | 2015-07-10 | | 公開日 | 2015-11-25 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.64 Å) | | 主引用文献 | Crystal Structures of SecYEG in Lipidic Cubic Phase Elucidate a Precise Resting and a Peptide-Bound State.
Cell Rep, 13, 2015
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6N3Q
 | | Cryo-EM structure of the yeast Sec complex | | 分子名称: | Protein translocation protein SEC63, Protein transport protein SBH1, Protein transport protein SEC61, ... | | 著者 | Park, E, Itskanov, S. | | 登録日 | 2018-11-16 | | 公開日 | 2018-12-19 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.68 Å) | | 主引用文献 | Structure of the posttranslational Sec protein-translocation channel complex from yeast.
Science, 363, 2019
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5EUL
 | | Structure of the SecA-SecY complex with a translocating polypeptide substrate | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, AYC08, BERYLLIUM TRIFLUORIDE ION, ... | | 著者 | Li, L, Park, E, Ling, J, Ingram, J, Ploegh, H, Rapoport, T.A. | | 登録日 | 2015-11-18 | | 公開日 | 2016-03-09 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | | 主引用文献 | Crystal structure of a substrate-engaged SecY protein-translocation channel.
Nature, 531, 2016
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7KB5
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6W6L
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7TUT
 | | Structure of the rabbit 80S ribosome stalled on a 4-TMD Rhodopsin intermediate in complex with the multipass translocon | | 分子名称: | 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | | 著者 | Kim, M.K, Lewis, A.J.O, Keenan, R.J, Hegde, R.S. | | 登録日 | 2022-02-03 | | 公開日 | 2022-10-19 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.88 Å) | | 主引用文献 | Mechanism of an intramembrane chaperone for multipass membrane proteins.
Nature, 611, 2022
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7KAS
 | | Cryo-EM structure of the Sec complex from S. cerevisiae, Sec63 FN3 mutant, class with Sec62 | | 分子名称: | Protein translocation protein SEC63, Protein transport protein SBH1, Protein transport protein SEC61, ... | | 著者 | Itskanov, S, Park, E. | | 登録日 | 2020-10-01 | | 公開日 | 2021-01-06 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Stepwise gating of the Sec61 protein-conducting channel by Sec63 and Sec62.
Nat.Struct.Mol.Biol., 28, 2021
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6R7Q
 | | Structure of XBP1u-paused ribosome nascent chain complex with Sec61. | | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | | 著者 | Shanmuganathan, V, Cheng, J, Braunger, K, Berninghausen, O, Beatrix, B, Beckmann, R. | | 登録日 | 2019-03-29 | | 公開日 | 2019-07-10 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structural and mutational analysis of the ribosome-arresting human XBP1u.
Elife, 8, 2019
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3J7R
 | | Structure of the translating mammalian ribosome-Sec61 complex | | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ... | | 著者 | Voorhees, R.M, Fernandez, I.S, Scheres, S.H.W, Hegde, R.S. | | 登録日 | 2014-08-01 | | 公開日 | 2014-09-03 | | 最終更新日 | 2019-10-30 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution.
Cell(Cambridge,Mass.), 157, 2014
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7KAO
 | | Cryo-EM structure of the Sec complex from S. cerevisiae, Sec61 pore mutant, class without Sec62 | | 分子名称: | Protein translocation protein SEC63, Protein transport protein SBH1, Protein transport protein SEC61, ... | | 著者 | Itskanov, S, Park, E. | | 登録日 | 2020-10-01 | | 公開日 | 2021-02-03 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Stepwise gating of the Sec61 protein-conducting channel by Sec63 and Sec62.
Nat.Struct.Mol.Biol., 28, 2021
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7KAQ
 | | Cryo-EM structure of the Sec complex from S. cerevisiae, Sec61 pore mutant, class with Sec62, conformation 2 (C2) | | 分子名称: | Protein translocation protein SEC63, Protein transport protein SBH1, Protein transport protein SEC61, ... | | 著者 | Itskanov, S, Park, E. | | 登録日 | 2020-10-01 | | 公開日 | 2021-01-06 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Stepwise gating of the Sec61 protein-conducting channel by Sec63 and Sec62.
Nat.Struct.Mol.Biol., 28, 2021
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7KAR
 | | Cryo-EM structure of the Sec complex from S. cerevisiae, Sec63 FN3 mutant, class without Sec62 | | 分子名称: | Protein translocation protein SEC63, Protein transport protein SBH1, Protein transport protein SEC61, ... | | 著者 | Itskanov, S, Park, E. | | 登録日 | 2020-10-01 | | 公開日 | 2021-01-06 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Stepwise gating of the Sec61 protein-conducting channel by Sec63 and Sec62.
Nat.Struct.Mol.Biol., 28, 2021
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7KAU
 | | Cryo-EM structure of the Sec complex from S. cerevisiae, Sec61 pore ring and Sec63 FN3 double mutant, class with Sec62 | | 分子名称: | Protein translocation protein SEC63, Protein transport protein SBH1, Protein transport protein SEC61, ... | | 著者 | Itskanov, S, Park, E. | | 登録日 | 2020-10-01 | | 公開日 | 2021-01-06 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Stepwise gating of the Sec61 protein-conducting channel by Sec63 and Sec62.
Nat.Struct.Mol.Biol., 28, 2021
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