Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

3RBF
DownloadVisualize
BU of 3rbf by Molmil
Crystal structure of Human aromatic L-amino acid decarboxylase (AADC) in the apo form
分子名称: Aromatic-L-amino-acid decarboxylase, CHLORIDE ION, PYRIDOXAL-5'-PHOSPHATE
著者Giardina, G, Montioli, R, Gianni, S, Cellini, B, Paiardini, A, Borri Voltattorni, C, Cutruzzola, F.
登録日2011-03-29
公開日2011-10-19
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Open conformation of human DOPA decarboxylase reveals the mechanism of PLP addition to Group II decarboxylases.
Proc.Natl.Acad.Sci.USA, 108, 2011
4E1O
DownloadVisualize
BU of 4e1o by Molmil
Human histidine decarboxylase complex with Histidine methyl ester (HME)
分子名称: HISTIDINE-METHYL-ESTER, Histidine decarboxylase, PYRIDOXAL-5'-PHOSPHATE
著者Komori, H, Nitta, Y, Ueno, H, Higuchi, Y.
登録日2012-03-06
公開日2012-07-18
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural study reveals that Ser-354 determines substrate specificity on human histidine decarboxylase
J.Biol.Chem., 287, 2012
3VP6
DownloadVisualize
BU of 3vp6 by Molmil
Structural characterization of Glutamic Acid Decarboxylase; insights into the mechanism of autoinactivation
分子名称: 4-oxo-4H-pyran-2,6-dicarboxylic acid, GLYCEROL, Glutamate decarboxylase 1
著者Langendorf, C.G, Tuck, K.L, Key, T.L.G, Rosado, C.J, Wong, A.S.M, Fenalti, G, Buckle, A.M, Law, R.H.P, Whisstock, J.C.
登録日2012-02-27
公開日2013-01-16
最終更新日2013-08-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural characterization of the mechanism through which human glutamic acid decarboxylase auto-activates
Biosci.Rep., 33, 2013
4Q6R
DownloadVisualize
BU of 4q6r by Molmil
Crystal structure of human sphingosine-1-phosphate lyase in complex with inhibitor 6-[(2R)-4-(4-benzyl-7-chlorophthalazin-1-yl)-2-methylpiperazin-1-yl]pyridine-3-carbonitrile
分子名称: 6-[(2R)-4-(4-benzyl-7-chlorophthalazin-1-yl)-2-methylpiperazin-1-yl]pyridine-3-carbonitrile, GLYCEROL, PHOSPHATE ION, ...
著者Srinivas, H.
登録日2014-04-23
公開日2014-05-21
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Orally Active 7-Substituted (4-Benzylphthalazin-1-yl)-2-methylpiperazin-1-yl]nicotinonitriles as Active-Site Inhibitors of Sphingosine 1-Phosphate Lyase for the Treatment of Multiple Sclerosis.
J.Med.Chem., 57, 2014
4RIT
DownloadVisualize
BU of 4rit by Molmil
The yellow crystal structure of pyridoxal-dependent decarboxylase from sphaerobacter thermophilus dsm 20745
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, GLYCEROL, ...
著者Wu, R, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2014-10-07
公開日2014-10-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The yellow crystal structure of pyridoxal-dependent decarboxylase from sphaerobacter thermophilus dsm 20745
To be Published
4OBU
DownloadVisualize
BU of 4obu by Molmil
Ruminococcus gnavus tryptophan decarboxylase RUMGNA_01526 (apo)
分子名称: PYRIDOXAL-5'-PHOSPHATE, Pyridoxal-dependent decarboxylase domain protein
著者Van Benschoten, A.H, Fraser, J.S.
登録日2014-01-07
公開日2014-10-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.804 Å)
主引用文献Discovery and Characterization of Gut Microbiota Decarboxylases that Can Produce the Neurotransmitter Tryptamine.
Cell Host Microbe, 16, 2014
4RLG
DownloadVisualize
BU of 4rlg by Molmil
The clear crystal structure of pyridoxal-dependent decarboxylase from sphaerobacter thermophilus dsm 20745
分子名称: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, GAMMA-AMINO-BUTANOIC ACID, GLYCEROL, ...
著者Wu, R, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2014-10-16
公開日2014-10-29
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.901 Å)
主引用文献The clear crystal structure of pyridoxal-dependent decarboxylase from sphaerobacter thermophilus dsm 20745
TO BE PUBLISHED
4OBV
DownloadVisualize
BU of 4obv by Molmil
Ruminococcus gnavus tryptophan decarboxylase RUMGNA_01526 (alpha-FMT)
分子名称: Pyridoxal-dependent decarboxylase domain protein, alpha-(fluoromethyl)-D-tryptophan, {5-hydroxy-4-[(1E)-4-(1H-indol-3-yl)-3-oxobut-1-en-1-yl]-6-methylpyridin-3-yl}methyl dihydrogen phosphate
著者Fraser, J.S, Van Benschoten, A.H.
登録日2014-01-07
公開日2014-10-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献Discovery and Characterization of Gut Microbiota Decarboxylases that Can Produce the Neurotransmitter Tryptamine.
Cell Host Microbe, 16, 2014
4W8I
DownloadVisualize
BU of 4w8i by Molmil
Crystal structure of LpSPL/Lpp2128, Legionella pneumophila sphingosine-1 phosphate lyase
分子名称: Probable sphingosine-1-phosphate lyase
著者Stogios, P.J, Daniels, C, Skarina, T, Cuff, M, Di Leo, R, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2014-08-24
公開日2014-11-05
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Legionella pneumophila S1P-lyase targets host sphingolipid metabolism and restrains autophagy.
Proc.Natl.Acad.Sci.USA, 113, 2016
4RM1
DownloadVisualize
BU of 4rm1 by Molmil
The crystal structure of Y333Q mutant pyridoxal-dependent decarboxylase from Sphaerobacter thermophilus DSM 20745
分子名称: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, CHLORIDE ION, GLYCEROL, ...
著者Wu, R, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2014-10-18
公開日2014-11-12
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献The crystal structure of Y333Q mutant pyridoxal-dependent decarboxylase from Sphaerobacter thermophilus DSM 20745
To be Published
4RIZ
DownloadVisualize
BU of 4riz by Molmil
The crystal structure of Y333Q mutant pyridoxal-dependent decarboxylase from Sphaerobacter thermophilus dsm 20745
分子名称: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, GLYCEROL, Pyridoxal-dependent decarboxylase, ...
著者Wu, R, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2014-10-07
公開日2014-11-12
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The crystal structure of y333q mutant pyridoxal-dependent decarboxylase from sphaerobacter thermophilus dsm 20745
To be Published
4RJ0
DownloadVisualize
BU of 4rj0 by Molmil
The crystal structure of Y333N mutant pyridoxal-dependent decarboxylase from Sphaerobacter thermophilus dsm 20745
分子名称: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, GLYCEROL, PHOSPHATE ION, ...
著者Wu, R, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2014-10-07
公開日2014-11-12
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The crystal structure of Y333N mutant pyridoxal-dependent decarboxylase from Sphaerobacter thermophilus dsm 20745
To be Published
5EUE
DownloadVisualize
BU of 5eue by Molmil
S1P Lyase Bacterial Surrogate bound to N-(2-((4-methoxy-2,5-dimethylbenzyl)amino)-1-phenylethyl)-5-methylisoxazole-3-carboxamide
分子名称: PHOSPHATE ION, Putative sphingosine-1-phosphate lyase, ~{N}-[(1~{S})-2-[(4-methoxy-2,5-dimethyl-phenyl)methylamino]-1-phenyl-ethyl]-5-methyl-1,2-oxazole-3-carboxamide
著者Argiriadi, M.A, Banach, D, Radziejewska, E, Marchie, S, DiMauro, J, Dinges, J, Dominguez, E, Hutchins, C, Judge, R.A, Queeney, K, Wallace, G, Harris, C.M.
登録日2015-11-18
公開日2016-03-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.83 Å)
主引用文献Creation of a S1P Lyase bacterial surrogate for structure-based drug design.
Bioorg.Med.Chem.Lett., 26, 2016
5EUD
DownloadVisualize
BU of 5eud by Molmil
S1P Lyase Bacterial Surrogate bound to N-(1-(4-(3-hydroxyprop-1-yn-1-yl)phenyl)-2-((4-methoxy-2,5-dimethylbenzyl)amino)ethyl)-5-methylisoxazole-3-carboxamide
分子名称: PHOSPHATE ION, Putative sphingosine-1-phosphate lyase, ~{N}-[(1~{S})-2-[(4-methoxy-2,5-dimethyl-phenyl)methylamino]-1-[4-(3-oxidanylprop-1-ynyl)phenyl]ethyl]-5-methyl-1,2-oxazole-3-carboxamide
著者Argiriadi, M.A, Banach, D, Radziejewska, E, Marchie, S, DiMauro, J, Dinges, J, Dominguez, E, Hutchins, C, Judge, R.A, Queeney, K, Wallace, G, Harris, C.M.
登録日2015-11-18
公開日2016-03-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Creation of a S1P Lyase bacterial surrogate for structure-based drug design.
Bioorg.Med.Chem.Lett., 26, 2016
5HSJ
DownloadVisualize
BU of 5hsj by Molmil
Structure of tyrosine decarboxylase complex with PLP at 1.9 Angstroms resolution
分子名称: PYRIDOXAL-5'-PHOSPHATE, Putative decarboxylase
著者Ni, Y, Zhou, J, Zhu, H, Zhang, K.
登録日2016-01-25
公開日2016-09-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of tyrosine decarboxylase and identification of key residues involved in conformational swing and substrate binding
Sci Rep, 6, 2016
5HSI
DownloadVisualize
BU of 5hsi by Molmil
Crystal structure of tyrosine decarboxylase at 1.73 Angstroms resolution
分子名称: MAGNESIUM ION, Putative decarboxylase
著者Ni, Y, Zhou, J, Zhu, H, Zhang, K.
登録日2016-01-25
公開日2016-09-21
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.732 Å)
主引用文献Crystal structure of tyrosine decarboxylase and identification of key residues involved in conformational swing and substrate binding
Sci Rep, 6, 2016
5K1R
DownloadVisualize
BU of 5k1r by Molmil
Structure of Burkholderia pseudomallei K96243 sphingosine-1-phosphate lyase Bpss2021
分子名称: Burkholderia pseudomallei sphingosine-1-phosphate lyase Bpss2021, PYRIDOXAL-5'-PHOSPHATE
著者Mclean, C.J, Campopiano, D.J, Marles-Wright, J.
登録日2016-05-18
公開日2016-11-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.104 Å)
主引用文献Characterization of homologous sphingosine-1-phosphate lyase isoforms in the bacterial pathogen Burkholderia pseudomallei.
J. Lipid Res., 58, 2017
5GP4
DownloadVisualize
BU of 5gp4 by Molmil
Lactobacillus brevis CGMCC 1306 Glutamate decarboxylase
分子名称: Glutamate decarboxylase, PYRIDOXAL-5'-PHOSPHATE
著者Mei, L, Huang, J.
登録日2016-07-31
公開日2017-08-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Lactobacillus brevis CGMCC 1306 glutamate decarboxylase: Crystal structure and functional analysis.
Biochem. Biophys. Res. Commun., 503, 2018
6ENZ
DownloadVisualize
BU of 6enz by Molmil
Crystal structure of mouse GADL1
分子名称: Acidic amino acid decarboxylase GADL1, PYRIDOXAL-5'-PHOSPHATE
著者Raasakka, A, Mahootchi, E, Winge, I, Luan, W, Kursula, P, Haavik, J.
登録日2017-10-07
公開日2018-01-03
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of the mouse acidic amino acid decarboxylase GADL1.
Acta Crystallogr F Struct Biol Commun, 74, 2018
5O5C
DownloadVisualize
BU of 5o5c by Molmil
The crystal structure of DfoJ, the desferrioxamine biosynthetic pathway lysine decarboxylase from the fire blight disease pathogen Erwinia amylovora
分子名称: PYRIDOXAL-5'-PHOSPHATE, Putative decarboxylase involved in desferrioxamine biosynthesis
著者Salomone-Stagni, M, Bartho, J.D, Polsinelli, I, Bellini, D, Walsh, M.A, Demitri, N, Benini, S.
登録日2017-06-01
公開日2018-02-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A complete structural characterization of the desferrioxamine E biosynthetic pathway from the fire blight pathogen Erwinia amylovora.
J. Struct. Biol., 202, 2018
6EEM
DownloadVisualize
BU of 6eem by Molmil
Crystal structure of Papaver somniferum tyrosine decarboxylase in complex with L-tyrosine
分子名称: N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)-L-tyrosine, SULFATE ION, TYROSINE, ...
著者Torrens-Spence, M.P, Chiang, Y, Smith, T, Vicent, M.A, Wang, Y, Weng, J.K.
登録日2018-08-14
公開日2018-09-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.61000657 Å)
主引用文献Structural basis for divergent and convergent evolution of catalytic machineries in plant aromatic amino acid decarboxylase proteins.
Proc.Natl.Acad.Sci.USA, 117, 2020
6EEQ
DownloadVisualize
BU of 6eeq by Molmil
Crystal structure of Rhodiola rosea 4-hydroxyphenylacetaldehyde synthase
分子名称: 4-hydroxyphenylacetaldehyde synthase
著者Torrens-Spence, M.P, Chiang, Y, Smith, T, Vicent, M.A, Wang, Y, Weng, J.K.
登録日2018-08-15
公開日2018-09-19
最終更新日2020-06-03
実験手法X-RAY DIFFRACTION (2.600086 Å)
主引用文献Structural basis for divergent and convergent evolution of catalytic machineries in plant aromatic amino acid decarboxylase proteins.
Proc.Natl.Acad.Sci.USA, 117, 2020
6EEI
DownloadVisualize
BU of 6eei by Molmil
Crystal structure of Arabidopsis thaliana phenylacetaldehyde synthase in complex with L-phenylalanine
分子名称: PHENYLALANINE, SULFATE ION, Tyrosine decarboxylase 1
著者Torrens-Spence, M.P, Chiang, Y, Smith, T, Vicent, M.A, Wang, Y, Weng, J.K.
登録日2018-08-14
公開日2018-09-19
最終更新日2020-06-03
実験手法X-RAY DIFFRACTION (1.99001348 Å)
主引用文献Structural basis for divergent and convergent evolution of catalytic machineries in plant aromatic amino acid decarboxylase proteins.
Proc.Natl.Acad.Sci.USA, 117, 2020
6EEW
DownloadVisualize
BU of 6eew by Molmil
Crystal structure of Catharanthus roseus tryptophan decarboxylase in complex with L-tryptophan
分子名称: Aromatic-L-amino-acid decarboxylase, CALCIUM ION, TRYPTOPHAN
著者Torrens-Spence, M.P, Chiang, Y, Smith, T, Vicent, M.A, Wang, Y, Weng, J.K.
登録日2018-08-15
公開日2018-09-19
最終更新日2020-06-03
実験手法X-RAY DIFFRACTION (2.05002069 Å)
主引用文献Structural basis for divergent and convergent evolution of catalytic machineries in plant aromatic amino acid decarboxylase proteins.
Proc.Natl.Acad.Sci.USA, 117, 2020
6EBN
DownloadVisualize
BU of 6ebn by Molmil
Crystal structure of Psilocybe cubensis noncanonical aromatic amino acid decarboxylase
分子名称: FORMIC ACID, GLYCEROL, SODIUM ION, ...
著者Torrens-Spence, M.P, Chun-Ting, L, Pluskal, T, Chung, Y.K, Weng, J.K.
登録日2018-08-06
公開日2018-12-12
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9663111 Å)
主引用文献Monoamine Biosynthesis via a Noncanonical Calcium-Activatable Aromatic Amino Acid Decarboxylase in Psilocybin Mushroom.
ACS Chem. Biol., 13, 2018

221051

件を2024-06-12に公開中

PDB statisticsPDBj update infoContact PDBjnumon