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7UZE
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Erythrocyte ankyrin-1 complex class 2 local refinement of AQP1 (C4 symmetry applied)
分子名称: Aquaporin-1, CHOLESTEROL
著者Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B.
登録日2022-05-09
公開日2022-07-20
最終更新日2022-07-27
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Architecture of the human erythrocyte ankyrin-1 complex.
Nat.Struct.Mol.Biol., 29, 2022
2W2E
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1.15 Angstrom crystal structure of P.pastoris aquaporin, Aqy1, in a closed conformation at pH 3.5
分子名称: AQUAPORIN PIP2-7 7, CHLORIDE ION, octyl beta-D-glucopyranoside
著者Fischer, G, Kosinska-Eriksson, U, Aponte-Santamaria, C, Palmgren, M, Geijer, C, Hedfalk, K, Hohmann, S, de Groot, B.L, Neutze, R, Lindkvist-Petersson, K.
登録日2008-10-29
公開日2009-06-16
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Crystal Structure of a Yeast Aquaporin at 1.15 A Reveals a Novel Gating Mechanism.1.15 A
Plos Biol., 7, 2009
1RC2
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2.5 Angstrom Resolution X-ray Structure of Aquaporin Z
分子名称: 2-O-octyl-beta-D-glucopyranose, Aquaporin Z
著者Savage, D.F, Egea, P.F, Robles, Y.C, O'Connell III, J.D, Stroud, R.M.
登録日2003-11-03
公開日2003-11-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Architecture and selectivity in aquaporins: 2.5 a X-ray structure of aquaporin Z
Plos Biol., 1, 2003
5DYE
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CRYSTAL STRUCTURE OF THE FULL LENGTH S156E MUTANT OF HUMAN AQUAPORIN 5
分子名称: Aquaporin-5, O-[(S)-{[(2S)-2-(hexanoyloxy)-3-(tetradecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-D-serine
著者Kitchen, P, Oeberg, F, Sjoehamn, J, Hedfalk, K, Bill, R.M, Conner, A.C, Conner, M.T, Toernroth-Horsefield, S.
登録日2015-09-24
公開日2015-12-02
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Plasma Membrane Abundance of Human Aquaporin 5 Is Dynamically Regulated by Multiple Pathways.
Plos One, 10, 2015
2W1P
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1.4 Angstrom crystal structure of P.pastoris aquaporin, Aqy1, in a closed conformation at pH 8.0
分子名称: AQUAPORIN PIP2-7 7;, CHLORIDE ION, octyl beta-D-glucopyranoside
著者Fischer, G, Kosinska-Eriksson, U, Aponte-Santamaria, C, Palmgren, M, Geijer, C, Hedfalk, K, Hohmann, S, de Groot, B.L, Neutze, R, Lindkvist-Petersson, K.
登録日2008-10-20
公開日2009-06-16
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal Structure of a Yeast Aquaporin at 1.15 A Reveals a Novel Gating Mechanism
Plos Biol., 7, 2009
5C5X
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CRYSTAL STRUCTURE OF THE S156E MUTANT OF HUMAN AQUAPORIN 5
分子名称: Aquaporin-5, O-[(S)-{[(2S)-2-(hexanoyloxy)-3-(tetradecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-D-serine
著者Kitchen, P, Oeberg, F, Sjoehamn, J, Hedfalk, K, Bill, R.M, Conner, A.C, Conner, M.T, Toernroth-Horsefield, S.
登録日2015-06-22
公開日2015-12-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Plasma Membrane Abundance of Human Aquaporin 5 Is Dynamically Regulated by Multiple Pathways.
Plos One, 10, 2015
3IYZ
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Structure of Aquaporin-4 S180D mutant at 10.0 A resolution from electron micrograph
分子名称: Aquaporin-4
著者Mitsuma, T, Tani, K, Hiroaki, Y, Kamegawa, A, Suzuki, H, Hibino, H, Kurachi, Y, Fujiyoshi, Y.
登録日2010-07-24
公開日2010-08-25
最終更新日2023-09-06
実験手法ELECTRON CRYSTALLOGRAPHY (10 Å)
主引用文献Influence of the cytoplasmic domains of aquaporin-4 on water conduction and array formation.
J.Mol.Biol., 402, 2010
1FQY
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STRUCTURE OF AQUAPORIN-1 AT 3.8 A RESOLUTION BY ELECTRON CRYSTALLOGRAPHY
分子名称: AQUAPORIN-1
著者Murata, K, Mitsuoka, K, Hirai, T, Walz, T, Agre, P, Heymann, J.B, Engel, A, Fujiyoshi, Y.
登録日2000-09-07
公開日2000-10-18
最終更新日2024-04-17
実験手法ELECTRON CRYSTALLOGRAPHY (3.8 Å)
主引用文献Structural determinants of water permeation through aquaporin-1.
Nature, 407, 2000
1FX8
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CRYSTAL STRUCTURE OF THE E. COLI GLYCEROL FACILITATOR (GLPF) WITH SUBSTRATE GLYCEROL
分子名称: GLYCEROL, GLYCEROL UPTAKE FACILITATOR PROTEIN, octyl beta-D-glucopyranoside
著者Fu, D, Libson, A, Miercke, L.J.W, Weitzman, C, Nollert, P, Stroud, R.M.
登録日2000-09-25
公開日2000-11-01
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of a glycerol-conducting channel and the basis for its selectivity.
Science, 290, 2000
8GCL
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Cryo-EM structure of hAQP2 in DDM
分子名称: Aquaporin-2
著者Kamegawa, A, Suzuki, S, Nishikawa, K, Numoto, N, Suzuki, H, Fujiyoshi, Y.
登録日2023-03-02
公開日2023-06-21
最終更新日2023-07-05
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural analysis of the water channel AQP2 by single-particle cryo-EM.
J.Struct.Biol., 215, 2023
8H1D
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Solid-state NMR Structure of Aquaporin Z in its Native Cellular Membranes
分子名称: Aquaporin Z
著者Xie, H, Zhao, Y, Zhao, W, Chen, Y, Liu, M, Yang, J.
登録日2022-10-02
公開日2022-11-09
最終更新日2024-05-15
実験手法SOLID-STATE NMR
主引用文献Solid-state NMR structure determination of a membrane protein in E. coli cellular inner membrane.
Sci Adv, 9, 2023
8GHJ
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Crystal structure of human AQP2 T125M mutant
分子名称: Aquaporin-2, CADMIUM ION
著者Horsefield, S, Hagstroemer, C.J.
登録日2023-03-10
公開日2023-09-20
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Structural and functional analysis of aquaporin-2 mutants involved in nephrogenic diabetes insipidus.
Sci Rep, 13, 2023
1Z98
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Crystal structure of the spinach aquaporin SoPIP2;1 in a closed conformation
分子名称: CADMIUM ION, aquaporin
著者Tornroth-Horsefield, S, Hedfalk, K, Johanson, U, Karlsson, M, Neutze, R, Kjellbom, P.
登録日2005-04-01
公開日2005-12-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural mechanism of plant aquaporin gating
Nature, 439, 2006
1H6I
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A REFINED STRUCTURE OF HUMAN AQUAPORIN 1
分子名称: AQUAPORIN-1
著者De Groot, B.L, Engel, A, Grubmuller, H.
登録日2001-06-15
公開日2001-12-13
最終更新日2024-05-01
実験手法ELECTRON CRYSTALLOGRAPHY (3.54 Å)
主引用文献A Refined Structure of Human Aquaporin 1
FEBS Lett., 504, 2001
1YMG
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The Channel Architecture of Aquaporin O at 2.2 Angstrom Resolution
分子名称: Lens fiber major intrinsic protein, nonyl beta-D-glucopyranoside
著者Harries, W.E.C, Akhavan, D, Miercke, L.J.W, Khademi, S, Stroud, R.M.
登録日2005-01-20
公開日2005-02-08
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献The Channel Architecture of Aquaporin 0 at a 2.2-A Resolution
Proc.Natl.Acad.Sci.USA, 101, 2004
2ABM
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Crystal Structure of Aquaporin Z Tetramer Reveals both Open and Closed Water-conducting Channels
分子名称: (1S)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PENTANOYLOXY)METHYL]ETHYL OCTANOATE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-O-octyl-beta-D-glucopyranose, ...
著者Jiang, J, Daniels, B.V, Fu, D.
登録日2005-07-15
公開日2005-09-20
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal Structure of AqpZ Tetramer Reveals Two Distinct Arg-189 Conformations Associated with Water Permeation through the Narrowest Constriction of the Water-conducting Channel.
J.Biol.Chem., 281, 2006
8JY6
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Structure of TbAQP2 in complex with anti-trypanosomatid drug melarsoprol
分子名称: Aquaglyceroporin 2, [(4~{R})-2-[4-[[4,6-bis(azanyl)-1,3,5-triazin-2-yl]amino]phenyl]-1,3,2-dithiarsolan-4-yl]methanol
著者Chen, W, Wang, C.
登録日2023-07-03
公開日2024-05-29
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Structural insights into drug transport by an aquaglyceroporin.
Nat Commun, 15, 2024
8JY8
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Structure of TbAQP2 in complex with anti-trypanosomatid drug pentamidine
分子名称: 1,5-BIS(4-AMIDINOPHENOXY)PENTANE, Aquaglyceroporin 2
著者Chen, W, Wang, C.
登録日2023-07-03
公開日2024-05-29
実験手法ELECTRON MICROSCOPY (2.45 Å)
主引用文献Structural insights into drug transport by an aquaglyceroporin.
Nat Commun, 15, 2024
8JY7
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Structure of the TbAQP2 in the apo conformation
分子名称: Aquaglyceroporin 2
著者Chen, W, Wang, C.
登録日2023-07-03
公開日2024-05-29
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural insights into drug transport by an aquaglyceroporin.
Nat Commun, 15, 2024
2O9D
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Crystal Structure of AqpZ mutant T183C.
分子名称: Aquaporin Z, octyl alpha-L-altropyranoside, octyl beta-D-galactopyranoside
著者Savage, D.F, Stroud, R.M, Center for Structures of Membrane Proteins (CSMP)
登録日2006-12-13
公開日2007-02-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis of aquaporin inhibition by mercury.
J.Mol.Biol., 368, 2007
8OEE
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Crystal structure of human AQP2 T126M mutant
分子名称: Aquaporin-2, CADMIUM ION
著者Horsefield, S, Hagstroemer, C.J.
登録日2023-03-10
公開日2023-09-20
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Structural and functional analysis of aquaporin-2 mutants involved in nephrogenic diabetes insipidus.
Sci Rep, 13, 2023
2O9G
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Crystal Structure of AqpZ mutant L170C complexed with mercury.
分子名称: Aquaporin Z, MERCURY (II) ION, octyl beta-D-glucopyranoside
著者Savage, D.F, Stroud, R.M, Center for Structures of Membrane Proteins (CSMP)
登録日2006-12-13
公開日2007-02-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis of aquaporin inhibition by mercury.
J.Mol.Biol., 368, 2007
2O9E
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Crystal Structure of AqpZ mutant T183C complexed with mercury
分子名称: Aquaporin Z, MERCURY (II) ION
著者Savage, D.F, Stroud, R.M, Center for Structures of Membrane Proteins (CSMP)
登録日2006-12-13
公開日2007-02-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis of aquaporin inhibition by mercury.
J.Mol.Biol., 368, 2007
2O9F
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Crystal Structure of AqpZ mutant L170C
分子名称: Aquaporin Z
著者Savage, D.F, Stroud, R.M, Center for Structures of Membrane Proteins (CSMP)
登録日2006-12-13
公開日2007-02-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structural basis of aquaporin inhibition by mercury.
J.Mol.Biol., 368, 2007
1J4N
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Crystal Structure of the AQP1 water channel
分子名称: AQUAPORIN 1, nonyl beta-D-glucopyranoside
著者Sui, H, Han, B.-G, Lee, J.K, Walian, P, Jap, B.K.
登録日2001-10-19
公開日2002-03-27
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis of water-specific transport through the AQP1 water channel.
Nature, 414, 2001

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