2W2E

1.15 Angstrom crystal structure of P.pastoris aquaporin, Aqy1, in a closed conformation at pH 3.5

Summary for 2W2E

Related2W1P
DescriptorAQUAPORIN PIP2-7 7, B-OCTYLGLUCOSIDE, CHLORIDE ION, ... (4 entities in total)
Functional Keywordsyeast, gating, membrane protein
Biological sourceKOMAGATAELLA PASTORIS
Total number of polymer chains1
Total molecular weight31793.01
Authors
Fischer, G.,Kosinska-Eriksson, U.,Aponte-Santamaria, C.,Palmgren, M.,Geijer, C.,Hedfalk, K.,Hohmann, S.,de Groot, B.L.,Neutze, R.,Lindkvist-Petersson, K. (deposition date: 2008-10-29, release date: 2009-06-16, Last modification date: 2019-05-22)
Primary citation
Fischer, G.,Kosinska-Eriksson, U.,Aponte-Santamaria, C.,Palmgren, M.,Geijer, C.,Hedfalk, K.,Hohmann, S.,De Groot, B.L.,Neutze, R.,Lindkvist-Petersson, K.
Crystal Structure of a Yeast Aquaporin at 1.15 A Reveals a Novel Gating Mechanism.1.15 A
Plos Biol., 7:E130-, 2009
PubMed: 19529756 (PDB entries with the same primary citation)
DOI: 10.1371/JOURNAL.PBIO.1000130
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.15 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.15930 3.1% 1.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report