PDB: 57 件ウェブページステータス検索Chemie searchBIRD

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4OFS	Crystal structure of a truncated catalytic core of the 2-oxoacid dehydrogenase multienzyme complex from Thermoplasma acidophilum 分子名称: Probable lipoamide acyltransferase 著者 Marrot, N.L, Marshall, J.J.T, Svergun, D.I, Crennell, S.J, Hough, D.W, van den Elsen, J.M.H, Danson, M.J. 登録日 2014-01-15 公開日 2014-12-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (4.1 Å) 主引用文献 Why are the 2-oxoacid dehydrogenase complexes so large? Generation of an active trimeric complex. Biochem.J., 463, 2014
6CT0	Atomic Structure of the E2 Inner Core of Human Pyruvate Dehydrogenase Complex 分子名称: Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial 著者 Jiang, J, Baiesc, F.L, Hiromasa, Y, Yu, X, Hui, W.H, Dai, X, Roche, T.E, Zhou, Z.H. 登録日 2018-03-21 公開日 2018-04-18 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Atomic Structure of the E2 Inner Core of Human Pyruvate Dehydrogenase Complex. Biochemistry, 57, 2018
6H05	Cryo-electron microscopic structure of the dihydrolipoamide succinyltransferase (E2) component of the human alpha-ketoglutarate (2-oxoglutarate) dehydrogenase complex [residues 218-453] 分子名称: Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial 著者 Nagy, B, Zambo, Z, Hubert, A, Polak, M, Nemeria, N.S, Novacek, J, Jordan, F, Adam-Vizi, V, Ambrus, A. 登録日 2018-07-06 公開日 2020-01-22 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structure of the dihydrolipoamide succinyltransferase (E2) component of the human alpha-ketoglutarate dehydrogenase complex (hKGDHc) revealed by cryo-EM and cross-linking mass spectrometry: Implications for the overall hKGDHc structure. Biochim Biophys Acta Gen Subj, 1865, 2021
6H55	core of the human pyruvate dehydrogenase (E2) 分子名称: Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial 著者 Haselbach, D, Prajapati, S, Tittmann, K, Stark, H. 登録日 2018-07-23 公開日 2019-06-05 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (6 Å) 主引用文献 Structural and Functional Analyses of the Human PDH Complex Suggest a "Division-of-Labor" Mechanism by Local E1 and E3 Clusters. Structure, 27, 2019
6H60	pseudo-atomic structural model of the E3BP component of the human pyruvate dehydrogenase multienzyme complex 分子名称: Pyruvate dehydrogenase protein X component, mitochondrial 著者 Haselbach, D, Prajapati, S, Tittmann, K, Stark, H. 登録日 2018-07-25 公開日 2019-06-05 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (6 Å) 主引用文献 Structural and Functional Analyses of the Human PDH Complex Suggest a "Division-of-Labor" Mechanism by Local E1 and E3 Clusters. Structure, 27, 2019
6PBR	Catalytic domain of E.coli dihydrolipoamide succinyltransferase in I4 space group 分子名称: Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, SODIUM ION 著者 Andi, B, Soares, A.S, Shi, W, Fuchs, M.R, McSweeney, S, Liu, Q. 登録日 2019-06-14 公開日 2019-06-26 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure of the dihydrolipoamide succinyltransferase catalytic domain from Escherichia coli in a novel crystal form: a tale of a common protein crystallization contaminant. Acta Crystallogr.,Sect.F, 75, 2019
6ZLM	Dihydrolipoyllysine-residue acetyltransferase component of fungal pyruvate dehydrogenase complex with protein X bound 分子名称: Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial, Pyruvate dehydrogenase X component 著者 Forsberg, B.O, Aibara, S, Howard, R.J, Mortezaei, N, Lindahl, E. 登録日 2020-06-30 公開日 2020-09-23 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Arrangement and symmetry of the fungal E3BP-containing core of the pyruvate dehydrogenase complex. Nat Commun, 11, 2020
6ZLO	E2 core of the fungal Pyruvate dehydrogenase complex with asymmetric interior PX30 component 分子名称: Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial 著者 Forsberg, B.O, Howard, R.J, Aibara, S, Mortesaei, N, Lindahl, E. 登録日 2020-06-30 公開日 2020-09-23 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Arrangement and symmetry of the fungal E3BP-containing core of the pyruvate dehydrogenase complex. Nat Commun, 11, 2020
6ZZN	Crystal structure of the cubic catalytic core of the Mycobacterium tuberculosis branched-chain alphaketoacid acyltransferase component (E2b). 分子名称: ACETATE ION, Dihydrolipoyllysine-residue acyltransferase component of branched-chain alpha-ketoacid dehydrogenase complex, IMIDAZOLE 著者 Vilela, P, Bellinzoni, M. 登録日 2020-08-04 公開日 2021-08-18 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Actinobacteria challenge the paradigm: A unique protein architecture for a well-known, central metabolic complex. Proc.Natl.Acad.Sci.USA, 118, 2021
6ZZJ	Crystal structure of the catalytic domain of Corynebacterium glutamicum acetyltransferase AceF (E2p) in complex with oxidized CoA. 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, OXIDIZED COENZYME A 著者 Bruch, E.M, Lexa-Sapart, N, Bellinzoni, M. 登録日 2020-08-04 公開日 2021-08-18 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Actinobacteria challenge the paradigm: A unique protein architecture for a well-known, central metabolic complex. Proc.Natl.Acad.Sci.USA, 118, 2021
6ZZL	Crystal structure of the catalytic domain plus N-terminal linker of the acetyltransferase AceF (E2p) from Corynebacterium glutamicum. 分子名称: Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, GLYCEROL, PHOSPHATE ION 著者 Yang, L, Bellinzoni, M. 登録日 2020-08-04 公開日 2021-08-18 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.229 Å) 主引用文献 Actinobacteria challenge the paradigm: A unique protein architecture for a well-known, central metabolic complex. Proc.Natl.Acad.Sci.USA, 118, 2021
6ZZI	Crystal structure of the catalyic domain of Corynebacterium glutamicum acetyltransferase AceF (E2p). 分子名称: Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex 著者 Bruch, E.M, Lexa-Sapart, N, Bellinzoni, M. 登録日 2020-08-04 公開日 2021-08-18 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.932 Å) 主引用文献 Actinobacteria challenge the paradigm: A unique protein architecture for a well-known, central metabolic complex. Proc.Natl.Acad.Sci.USA, 118, 2021
6ZZM	Crystal structure of the catalytic domain of Corynebacterium mustelae predicted acetyltransferase AceF (E2p). 分子名称: COENZYME A, Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex 著者 Bruch, E.M, Bellinzoni, M. 登録日 2020-08-04 公開日 2021-08-18 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Actinobacteria challenge the paradigm: A unique protein architecture for a well-known, central metabolic complex. Proc.Natl.Acad.Sci.USA, 118, 2021
6ZZK	Crystal structure of the catalytic domain of C. glutamicum AceF (E2p) in ternary complex with CoA and dihydrolipoamide. 分子名称: 6,8-DIMERCAPTO-OCTANOIC ACID AMIDE, COENZYME A, Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex 著者 Bruch, E.M, Bellinzoni, M. 登録日 2020-08-04 公開日 2021-08-18 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Actinobacteria challenge the paradigm: A unique protein architecture for a well-known, central metabolic complex. Proc.Natl.Acad.Sci.USA, 118, 2021
7B9K	Cryo-EM structure of the dihydrolipoyl transacetylase cubic core of the E. coli pyruvate dehydrogenase complex including lipoyl domains 分子名称: Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex 著者 Skerlova, J, Stenmark, P. 登録日 2020-12-14 公開日 2021-08-11 最終更新日 2021-10-06 実験手法 ELECTRON MICROSCOPY (3.16 Å) 主引用文献 Structure of the native pyruvate dehydrogenase complex reveals the mechanism of substrate insertion. Nat Commun, 12, 2021
7BGJ	C. thermophilum Pyruvate Dehydrogenase Complex Core 分子名称: Acetyltransferase component of pyruvate dehydrogenase complex 著者 Tueting, C, Kastritis, P.L. 登録日 2021-01-07 公開日 2021-02-10 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (6.9 Å) 主引用文献 Integrative structure of a 10-megadalton eukaryotic pyruvate dehydrogenase complex from native cell extracts. Cell Rep, 34, 2021
7OTT	Metabolon-embedded pyruvate dehydrogenase complex E2 core at near-atomic resolution 分子名称: Acetyltransferase component of pyruvate dehydrogenase complex 著者 Tueting, C, Kastritis, P.L. 登録日 2021-06-10 公開日 2021-12-01 最終更新日 2021-12-08 実験手法 ELECTRON MICROSCOPY (3.84 Å) 主引用文献 Cryo-EM snapshots of a native lysate provide structural insights into a metabolon-embedded transacetylase reaction. Nat Commun, 12, 2021
7Q5R	Protein community member pyruvate dehydrogenase complex E2 core from C. thermophilum 分子名称: Acetyltransferase component of pyruvate dehydrogenase complex 著者 Chojnowski, G, Skalidis, I, Kyrilis, F.L, Tueting, C, Hamdi, F, Kastritis, P.L. 登録日 2021-11-04 公開日 2022-02-02 最終更新日 2023-12-13 実験手法 ELECTRON MICROSCOPY (3.84 Å) 主引用文献 Cryo-EM and artificial intelligence visualize endogenous protein community members. Structure, 30, 2022
7Q5Q	Protein community member oxoglutarate dehydrogenase complex E2 core from C. thermophilum 分子名称: Dihydrolipoyllysine-residue succinyltransferase 著者 Chojnowski, G, Skalidis, I, Kyrilis, F.L, Tueting, C, Hamdi, F, Kastritis, P.L. 登録日 2021-11-04 公開日 2022-02-02 最終更新日 2023-12-13 実験手法 ELECTRON MICROSCOPY (4.38 Å) 主引用文献 Cryo-EM and artificial intelligence visualize endogenous protein community members. Structure, 30, 2022
7R5M	Core-binding domain of fungal E3-binding domain bound to the pyruvate dehydrogenase E2 core 分子名称: Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial, Pyruvate dehydrogenase X component 著者 Forsberg, B.O. 登録日 2022-02-11 公開日 2023-01-18 最終更新日 2023-05-24 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 The structure and evolutionary diversity of the fungal E3-binding protein. Commun Biol, 6, 2023
7UOL	Endogenous dihydrolipoamide succinyltransferase (E2) core of 2-oxoglutarate dehydrogenase complex from bovine kidney 分子名称: Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial 著者 Liu, S, Xia, X, Zhen, J, Li, Z.H, Zhou, Z.H. 登録日 2022-04-13 公開日 2022-11-30 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structures and comparison of endogenous 2-oxoglutarate and pyruvate dehydrogenase complexes from bovine kidney. Cell Discov, 8, 2022
8OHS	Core-binding domain of fungal E3-binding domain bound to the native pyruvate dehydrogenase E2 core 分子名称: Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial, Pyruvate dehydrogenase X component 著者 Forsberg, B.O. 登録日 2023-03-21 公開日 2023-04-26 最終更新日 2023-05-24 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 The structure and evolutionary diversity of the fungal E3-binding protein. Commun Biol, 6, 2023
8OIU	Cryo-EM reconstruction of the native 24-mer E2o core of the 2-oxoglutarate dehydrogenase complex of C. thermophilum at 3.35 A resolution 分子名称: Dihydrolipoyllysine-residue succinyltransferase 著者 Skalidis, I, Tueting, C, Kyrilis, F.L, Hamdi, F, Kastritis, P.L. 登録日 2023-03-23 公開日 2023-05-31 実験手法 ELECTRON MICROSCOPY (3.35 Å) 主引用文献 Structural analysis of an endogenous 4-megadalton succinyl-CoA-generating metabolon. Commun Biol, 6, 2023
8ORB	24-meric catalytic domain of dihydrolipoamide acetyltransferase (E2) of the E. coli pyruvate dehydrogenase complex. 分子名称: Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex 著者 Zdanowicz, R, Meinhold, S, Glockshuber, R. 登録日 2023-04-13 公開日 2024-02-07 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (3.25 Å) 主引用文献 Dimerization of a 5-kDa domain defines the architecture of the 5-MDa gammaproteobacterial pyruvate dehydrogenase complex. Sci Adv, 10, 2024
8OSY	Trimeric catalytic domain of the E. coli Dihydrolipoamide Acetyltransferase (E2) of the pyruvate dehydrogenase complex 分子名称: Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex 著者 Meinhold, S, Zdanowicz, R, Glockshuber, R. 登録日 2023-04-20 公開日 2024-02-07 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Dimerization of a 5-kDa domain defines the architecture of the 5-MDa gammaproteobacterial pyruvate dehydrogenase complex. Sci Adv, 10, 2024

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