PDB: 112 件ウェブページステータス検索Chemie searchBIRD

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6LC1	Structural basis of NR4A1 bound to the human pituitary proopiomelanocortin gene promoter 分子名称: DNA, DNA (25-MER), Nuclear receptor subfamily 4 group A member 1, ... 著者 Jiang, L, Chen, Y. 登録日 2019-11-16 公開日 2019-12-18 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.12 Å) 主引用文献 Structural basis of NR4A1 bound to the human pituitary proopiomelanocortin gene promoter. Biochem.Biophys.Res.Commun., 523, 2020
5VA0	Glucocorticoid Receptor DNA Binding Domain in complex with AP-1 response element from VCAM-1 Promoter 分子名称: DNA (5'-D(*CP*GP*GP*CP*TP*GP*AP*CP*TP*CP*AP*TP*CP*AP*AP*G)-3'), DNA (5'-D(*CP*TP*TP*GP*AP*TP*GP*AP*GP*TP*CP*AP*GP*CP*CP*G)-3'), Glucocorticoid receptor, ... 著者 Weikum, E.R, Ortlund, E.A. 登録日 2017-03-24 公開日 2017-08-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.295 Å) 主引用文献 Tethering not required: the glucocorticoid receptor binds directly to activator protein-1 recognition motifs to repress inflammatory genes. Nucleic Acids Res., 45, 2017
6FBQ	Crystal Structure of the Human Retinoid X Receptor DNA-Binding Domain Bound to the Human MEp DR1 Response Element, pH 7.0 分子名称: 3[N-MORPHOLINO]PROPANE SULFONIC ACID, DNA (5'-D(*CP*TP*GP*GP*GP*TP*CP*AP*AP*AP*GP*TP*TP*CP*AP*TP*C)-3'), DNA (5'-D(*GP*AP*TP*GP*AP*AP*CP*TP*TP*TP*GP*AP*CP*CP*CP*AP*G)-3'), ... 著者 McEwen, A.G, Poussin-Courmontagne, P, Osz, J, Rochel, N. 登録日 2017-12-19 公開日 2018-12-05 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Modulation of RXR-DNA complex assembly by DNA context. Mol. Cell. Endocrinol., 481, 2019
6FBR	Crystal Structure of the Human Retinoid X Receptor DNA-Binding Domain Bound to the Human MEp DR1 Response Element, pH 4.2 分子名称: DI(HYDROXYETHYL)ETHER, DNA (5'-D(*CP*TP*GP*GP*GP*TP*CP*AP*AP*AP*GP*TP*TP*CP*AP*TP*C)-3'), DNA (5'-D(*GP*AP*TP*GP*AP*AP*CP*TP*TP*TP*GP*AP*CP*CP*CP*AP*G)-3'), ... 著者 McEwen, A.G, Poussin-Courmontagne, P, Osz, J, Rochel, N. 登録日 2017-12-19 公開日 2018-12-05 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Modulation of RXR-DNA complex assembly by DNA context. Mol. Cell. Endocrinol., 481, 2019
5VA7	Glucocorticoid Receptor DNA Binding Domain - IL11 AP-1 recognition element Complex 分子名称: DNA (5'-D(*AP*GP*GP*GP*TP*GP*AP*GP*TP*CP*AP*GP*GP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*CP*CP*TP*GP*AP*CP*TP*CP*AP*CP*CP*CP*T)-3'), Glucocorticoid receptor, ... 著者 Weikum, E.R, Ortlund, E.A. 登録日 2017-03-24 公開日 2017-08-09 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.153 Å) 主引用文献 Tethering not required: the glucocorticoid receptor binds directly to activator protein-1 recognition motifs to repress inflammatory genes. Nucleic Acids Res., 45, 2017
8HBM	Structural basis of the farnesoid X receptor/retinoid X receptor heterodimer on inverted repeat DNA 分子名称: Bile acid receptor, DNA (5'-D(P*CP*CP*GP*AP*GP*GP*TP*CP*AP*AP*TP*GP*AP*CP*CP*TP*CP*G)-3'), DNA (5'-D(P*CP*CP*GP*AP*GP*GP*TP*CP*AP*TP*TP*GP*AP*CP*CP*TP*CP*G)-3'), ... 著者 Jiang, L, Chen, Y. 登録日 2022-10-29 公開日 2023-06-14 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structural basis of the farnesoid X receptor/retinoid X receptor heterodimer on inverted repeat DNA. Comput Struct Biotechnol J, 21, 2023
6XWG	Crystal Structure of the Human RXR/RAR DNA-Binding Domain Heterodimer Bound to the Human RARb2 DR5 Response Element 分子名称: CHLORIDE ION, GLYCEROL, RARb2 DR5 Response Element, ... 著者 McEwen, A.G, Poussin-Courmontagne, P, Peluso-Iltis, C, Rochel, N. 登録日 2020-01-23 公開日 2020-09-09 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural basis for DNA recognition and allosteric control of the retinoic acid receptors RAR-RXR. Nucleic Acids Res., 48, 2020
6XWH	Crystal Structure of the Human RXR DNA-Binding Domain Homodimer Bound to the Human Hoxb13 DR0 Response Element 分子名称: Hoxb13 DR0 Response Element, 3'-5' strand, 5'-3' strand, ... 著者 McEwen, A.G, Poussin-Courmontagne, P, Peluso-Iltis, C, Rochel, N. 登録日 2020-01-23 公開日 2020-09-09 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural basis for DNA recognition and allosteric control of the retinoic acid receptors RAR-RXR. Nucleic Acids Res., 48, 2020
6X6E	Glucocorticoid Receptor DNA binding domain in complex with methylated precursor for a modern recognition element (methylated pre-GBS) 分子名称: DNA (5'-D(*CP*CP*AP*GP*AP*AP*CP*GP*GP*AP*GP*(5CM)P*GP*TP*TP*CP*TP*G)-3'), DNA (5'-D(*TP*CP*AP*GP*AP*AP*CP*GP*CP*TP*CP*(5CM)P*GP*TP*TP*CP*TP*G)-3'), Glucocorticoid receptor, ... 著者 Liu, X, Ortlund, E.A. 登録日 2020-05-28 公開日 2021-06-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis for glucocorticoid receptor recognition of both unmodified and methylated binding sites, precursors of a modern recognition element. Nucleic Acids Res., 49, 2021
6X6D	Glucocorticoid Receptor DNA binding domain in complex with unmodified precursor for a modern recognition element (pre-GBS) 分子名称: CACODYLATE ION, DNA (5'-D(*CP*CP*AP*GP*AP*AP*CP*GP*GP*AP*GP*CP*GP*TP*TP*CP*TP*G)-3'), DNA (5'-D(*TP*CP*AP*GP*AP*AP*CP*GP*CP*TP*CP*CP*GP*TP*TP*CP*TP*G)-3'), ... 著者 Liu, X, Ortlund, E.A. 登録日 2020-05-28 公開日 2021-06-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 Structural basis for glucocorticoid receptor recognition of both unmodified and methylated binding sites, precursors of a modern recognition element. Nucleic Acids Res., 49, 2021
4CN2	Crystal Structure of the Human Retinoid X Receptor DNA-Binding Domain Bound to the Human Ramp2 Response Element 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5'-D(*AP*TP*TP*GP*AP*CP*CP*CP*TP*TP*GP*AP*AP*DC *TP*CP*AP)-3', 5'-D(*TP*GP*AP*GP*TP*TP*CP*AP*AP*GP*GP*GP*TP*DC *AP*AP*TP)-3', ... 著者 McEwen, A.G, Poussin-Courmontagne, P, Osz, J, Rochel, N. 登録日 2014-01-21 公開日 2015-02-18 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.069 Å) 主引用文献 Structural Basis of Natural Promoter Recognition by the Retinoid X Nuclear Receptor. Sci.Rep., 5, 2015
4CN7	Crystal Structure of the Human Retinoid X Receptor DNA-Binding Domain Bound to an idealized DR1 Response Element 分子名称: 5'-D(*CP*TP*AP*GP*GP*TP*CP*AP*AP*AP*GP*GP*TP*CP *AP*GP)-3', 5'-D(*CP*TP*GP*AP*CP*CP*TP*TP*TP*GP*AP*CP*CP*TP *AP*GP)-3', CHLORIDE ION, ... 著者 McEwen, A.G, Poussin-Courmontagne, P, Osz, J, Rochel, N. 登録日 2014-01-21 公開日 2015-02-18 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Structural Basis of Natural Promoter Recognition by the Retinoid X Nuclear Receptor. Sci.Rep., 5, 2015
4CN3	Crystal Structure of the Human Retinoid X Receptor DNA-Binding Domain Bound to the Human Gde1SpA Response Element 分子名称: 5'-D(*CP*TP*AP*GP*TP*TP*CP*AP*AP*AP*GP*TP*TP*CP *AP*CP*A)-3', 5'-D(*TP*GP*TP*GP*AP*AP*CP*TP*TP*TP*GP*AP*AP*CP *TP*AP*G)-3', RETINOIC ACID RECEPTOR RXR-ALPHA, ... 著者 McEwen, A.G, Poussin-Courmontagne, P, Osz, J, Rochel, N. 登録日 2014-01-21 公開日 2015-02-18 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structural Basis of Natural Promoter Recognition by the Retinoid X Nuclear Receptor. Sci.Rep., 5, 2015
6BQU	Human GR (418-507) in complex with monomeric DNA binding site 分子名称: DNA (5'-D(P*AP*AP*GP*CP*TP*AP*GP*TP*AP*CP*AP*TP*TP*TP*GP*C)-3'), DNA (5'-D(P*TP*GP*CP*AP*AP*AP*TP*GP*TP*AP*CP*TP*AP*GP*CP*T)-3'), Glucocorticoid receptor, ... 著者 Pufall, M.A. 登録日 2017-11-28 公開日 2018-12-05 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 General and sequence-specific roles for DNA in glucocorticoid receptor DNA-binding stoichiometry To Be Published
6BSF	Human GR (418-507) in complex with monomeric DNA binding site 分子名称: DNA (5'-D(P*AP*AP*GP*CP*TP*AP*GP*TP*AP*CP*AP*TP*TP*TP*GP*C)-3'), DNA (5'-D(P*TP*GP*CP*AP*AP*AP*TP*GP*TP*AP*CP*TP*AP*GP*CP*T)-3'), Glucocorticoid receptor, ... 著者 Pufall, M.A. 登録日 2017-12-02 公開日 2018-12-05 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 General and sequence-specific roles for DNA in glucocorticoid receptor DNA-binding stoichiometry To Be Published
1A6Y	REVERBA ORPHAN NUCLEAR RECEPTOR/DNA COMPLEX 分子名称: DNA (5'-D(*CP*AP*AP*CP*TP*AP*GP*GP*TP*CP*AP*CP*(5IT)P*AP*GP*GP*TP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*AP*CP*CP*TP*AP*GP*TP*GP*AP*CP*CP*TP*AP*GP*TP*TP*G)-3'), ORPHAN NUCLEAR RECEPTOR NR1D1, ... 著者 Zhao, Q, Khorasanizadeh, S, Rastinejad, F. 登録日 1998-03-04 公開日 1998-10-21 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural elements of an orphan nuclear receptor-DNA complex. Mol.Cell, 1, 1998
6CFN	Crystal Structure of the DNA-free Glucocorticoid Receptor DNA Binding Domain 分子名称: Glucocorticoid receptor, ZINC ION 著者 Frank, F, Okafor, C.D, Ortlund, E.A. 登録日 2018-02-15 公開日 2018-09-26 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The first crystal structure of a DNA-free nuclear receptor DNA binding domain sheds light on DNA-driven allostery in the glucocorticoid receptor. Sci Rep, 8, 2018
2C7A	STRUCTURE OF THE PROGESTERONE RECEPTOR-DNA COMPLEX 分子名称: 5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*AP*AP *CP*TP*GP*TP*TP*CP*TP*G)-3', 5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*GP*TP *TP*TP*GP*TP*TP*CP*TP*G)-3', PROGESTERONE RECEPTOR, ... 著者 Roemer, S.C, Donham, D.C, Sherman, L, Pon, V.H, Edwards, D.P, Churchill, M.E.A. 登録日 2005-11-19 公開日 2006-08-30 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of the Progesterone Receptor-Deoxyribonucleic Acid Complex: Novel Interactions Required for Binding to Half-Site Response Elements. Mol.Endocrinol., 20, 2006
1CIT	DNA-BINDING MECHANISM OF THE MONOMERIC ORPHAN NUCLEAR RECEPTOR NGFI-B 分子名称: DNA (5'-D(*CP*CP*GP*AP*AP*AP*AP*GP*GP*TP*CP*AP*TP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*AP*TP*GP*AP*CP*CP*TP*TP*TP*TP*CP*GP*G)-3'), PROTEIN (ORPHAN NUCLEAR RECEPTOR NGFI-B), ... 著者 Meinke, G, Sigler, P.B. 登録日 1999-04-05 公開日 1999-05-03 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 DNA-binding mechanism of the monomeric orphan nuclear receptor NGFI-B. Nat.Struct.Biol., 6, 1999
2ENV	Solution structure of the C4-type zinc finger domain from human Peroxisome proliferator-activated receptor delta 分子名称: Peroxisome proliferator-activated receptor delta, ZINC ION 著者 Nagashima, T, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-03-28 公開日 2008-04-08 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Solution structure of the C4-type zinc finger domain from human Peroxisome proliferator-activated receptor delta To be Published
1BY4	STRUCTURE AND MECHANISM OF THE HOMODIMERIC ASSEMBLY OF THE RXR ON DNA 分子名称: DNA (5'-D(*C*TP*AP*GP*GP*TP*CP*AP*AP*AP*GP*GP*TP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*AP*CP*CP*TP*TP*TP*GP*AP*CP*CP*TP*A)-3'), PROTEIN (RETINOIC ACID RECEPTOR RXR-ALPHA), ... 著者 Zhao, Q, Chasse, S.A, Devarakonda, S, Sierk, M.L, Ahvazi, B, Sigler, P.B, Rastinejad, F. 登録日 1998-10-22 公開日 2000-01-12 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural basis of RXR-DNA interactions. J.Mol.Biol., 296, 2000
4CN5	Crystal Structure of the Human Retinoid X Receptor DNA-Binding Domain Bound to the Human Nr1d1 Response Element 分子名称: 5'-D(*AP*TP*TP*GP*AP*AP*CP*TP*CP*TP*GP*AP*CP*CP *CP*CP*AP)-3', 5'-D(*TP*GP*GP*GP*GP*TP*CP*AP*GP*AP*GP*TP*TP*CP *AP*AP*TP)-3', CHLORIDE ION, ... 著者 McEwen, A.G, Poussin-Courmontagne, P, Osz, J, Rochel, N. 登録日 2014-01-21 公開日 2015-02-18 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Basis of Natural Promoter Recognition by the Retinoid X Nuclear Receptor. Sci.Rep., 5, 2015
6BSE	Glucocorticoid receptor bound to high cooperativity monomer sequence 分子名称: DNA (5'-D(P*AP*CP*CP*AP*CP*GP*TP*GP*TP*AP*CP*TP*TP*TP*TP*T)-3'), DNA (5'-D(P*TP*AP*AP*AP*AP*AP*GP*TP*AP*CP*AP*CP*GP*TP*GP*G)-3'), Glucocorticoid receptor, ... 著者 Pufall, M.A. 登録日 2017-12-02 公開日 2018-12-05 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 General and sequence-specific roles for DNA in glucocorticoid receptor DNA-binding stoichiometry To Be Published
1DSZ	STRUCTURE OF THE RXR/RAR DNA-BINDING DOMAIN HETERODIMER IN COMPLEX WITH THE RETINOIC ACID RESPONSE ELEMENT DR1 分子名称: DNA (5'-D(*CP*AP*GP*GP*TP*CP*AP*AP*AP*GP*GP*TP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*AP*CP*CP*TP*TP*TP*GP*AP*CP*CP*TP*G)-3'), RETINOIC ACID RECEPTOR ALPHA, ... 著者 Rastinejad, F, Wagner, T, Zhao, Q, Khorasanizadeh, S. 登録日 2000-01-10 公開日 2000-07-10 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structure of the RXR-RAR DNA-binding complex on the retinoic acid response element DR1. EMBO J., 19, 2000
2EBL	Solution structure of the Zinc finger, C4-type domain of human COUP transcription factor 1 分子名称: COUP transcription factor 1, ZINC ION 著者 Yoneyama, M, Koshiba, S, Watabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-02-09 公開日 2008-02-19 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the Zinc finger, C4-type domain of human COUP transcription factor 1 To be Published

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