6XWH

Crystal Structure of the Human RXR DNA-Binding Domain Homodimer Bound to the Human Hoxb13 DR0 Response Element

Summary for 6XWH

Entry DOI	10.2210/pdb6xwh/pdb
Descriptor	Hoxb13 DR0 Response Element, 5'-3' strand, Hoxb13 DR0 Response Element, 3'-5' strand, Retinoic acid receptor RXR-alpha, ... (5 entities in total)
Functional Keywords	protein-dna complex, nuclear receptor, transcription
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	30584.86
Authors	McEwen, A.G.,Poussin-Courmontagne, P.,Peluso-Iltis, C.,Rochel, N. (deposition date: 2020-01-23, release date: 2020-09-09, Last modification date: 2024-01-24)
Primary citation	Osz, J.,McEwen, A.G.,Bourguet, M.,Przybilla, F.,Peluso-Iltis, C.,Poussin-Courmontagne, P.,Mely, Y.,Cianferani, S.,Jeffries, C.M.,Svergun, D.I.,Rochel, N. Structural basis for DNA recognition and allosteric control of the retinoic acid receptors RAR-RXR. Nucleic Acids Res., 48:9969-9985, 2020 Cited by PubMed: 32974652 DOI: 10.1093/nar/gkaa697 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation