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1DS3
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CRYSTAL STRUCTURE OF OMTKY3-CH2-ASP19I
分子名称: OVOMUCOID
著者Bateman, K.S, Huang, K, Anderson, S, Lu, W, Qasim, M.A, Laskowski Jr, M, James, M.N.G.
登録日2000-01-06
公開日2001-01-31
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Contribution of peptide bonds to inhibitor-protease binding: crystal structures of the turkey ovomucoid third domain backbone variants OMTKY3-Pro18I and OMTKY3-psi[COO]-Leu18I in complex with Streptomyces griseus proteinase B (SGPB) and the structure of the free inhibitor, OMTKY-3-psi[CH2NH2+]-Asp19I
J.Mol.Biol., 305, 2001
1TUS
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SOLUTION STRUCTURE OF REACTIVE-SITE HYDROLYZED TURKEY OVOMUCOID THIRD DOMAIN BY NUCLEAR MAGNETIC RESONANCE AND DISTANCE GEOMETRY METHODS
分子名称: OVOMUCOID
著者Walkenhorst, W.F, Krezel, A.M, Rhyu, G.I, Markley, J.L.
登録日1994-07-06
公開日1994-10-15
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Solution structure of reactive-site hydrolyzed turkey ovomucoid third domain by nuclear magnetic resonance and distance geometry methods.
J.Mol.Biol., 242, 1994
1UVF
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Solution Structure of the structured part of the 15th Domain of LEKTI
分子名称: SERINE PROTEINASE INHIBITOR KAZAL TYPE 5
著者Vitzithum, K, Roesch, P, Marx, U.C.
登録日2004-01-20
公開日2005-04-14
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献The Solution Structure of a Chimeric Lekti Domain Reveals a Chameleon Sequence
Biochemistry, 43, 2004
1UVG
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Solution structure of the 15th Domain of LEKTI
分子名称: SERINE PROTEINASE INHIBITOR KAZAL TYPE 5
著者Vitzithum, K, Roesch, P, Marx, U.C.
登録日2004-01-20
公開日2005-04-14
最終更新日2019-10-30
実験手法SOLUTION NMR
主引用文献The Solution Structure of a Chimeric Lekti Domain Reveals a Chameleon Sequence
Biochemistry, 43, 2004
1TUR
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SOLUTION STRUCTURE OF TURKEY OVOMUCOID THIRD DOMAIN AS DETERMINED FROM NUCLEAR MAGNETIC RESONANCE DATA
分子名称: OVOMUCOID
著者Krezel, A.M, Darba, P, Robertson, A.D, Fejzo, J, Macura, S, Markley, J.L.
登録日1994-07-06
公開日1994-10-15
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Solution structure of turkey ovomucoid third domain as determined from nuclear magnetic resonance data.
J.Mol.Biol., 242, 1994
6KBR
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Crystal structure of Human KLK4 and SPINK2 derived KLK4 inhibitor complex
分子名称: GLYCEROL, K41043, Kallikrein-4
著者Kawaguchi, Y, Nishimiya, D.
登録日2019-06-26
公開日2019-07-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A protein scaffold, engineered SPINK2, for generation of inhibitors with high affinity and specificity against target proteases.
Sci Rep, 9, 2019
7E50
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Crystal structure of human microplasmin in complex with kazal-type inhibitor AaTI
分子名称: AAEL006007-PA, GLYCEROL, Plasminogen, ...
著者Varsha, A.W, Jobichen, C, Mok, Y.K.
登録日2021-02-16
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of Aedes aegypti trypsin inhibitor in complex with mu-plasmin reveals role for scaffold stability in Kazal-type serine protease inhibitor.
Protein Sci., 31, 2022
8IVD
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BU of 8ivd by Molmil
COMPLEX STRUCTURE OF CD93-IGFBP7
分子名称: Insulin-like growth factor-binding protein 7,Complement component C1q receptor
著者Xu, Y.M, Song, G.J.
登録日2023-03-27
公開日2024-01-17
最終更新日2024-08-14
実験手法X-RAY DIFFRACTION (3.24 Å)
主引用文献Structural insight into CD93 recognition by IGFBP7.
Structure, 32, 2024
5DAE
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Kazal type inhibitor from salivary glands of Aedes aegypti mosquito
分子名称: AAEL006007-PA
著者Torquato, R.J.S, Pereira, P.J.B, Tanaka, A.S.
登録日2015-08-19
公開日2016-09-07
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献High-resolution structure of a Kazal-type serine protease inhibitor from the dengue vector Aedes aegypti.
Acta Crystallogr F Struct Biol Commun, 73, 2017
4OVO
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REFINED X-RAY CRYSTAL STRUCTURES OF THE REACTIVE SITE MODIFIED OVOMUCOID INHIBITOR THIRD DOMAINS FROM SILVER PHEASANT (OMSVP3(ASTERISK)) AND FROM JAPANESE QUAIL (OMJPQ3(ASTERISK))
分子名称: OVOMUCOID THIRD DOMAIN CLEAVED RDI
著者Musil, D, Bode, W.
登録日1991-05-13
公開日1993-01-15
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Refined X-ray crystal structures of the reactive site modified ovomucoid inhibitor third domains from silver pheasant (OMSVP3*) and from Japanese quail (OMJPQ3*).
J.Mol.Biol., 220, 1991
7QE8
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Human cationic trypsin (TRY1) complexed with serine protease inhibitor Kazal type 1 (SPINK1)
分子名称: SULFATE ION, Serine protease inhibitor Kazal-type 1, Trypsin-1
著者Nagel, F, Palm, G.J, Delcea, M, Lammers, M.
登録日2021-12-01
公開日2022-03-30
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural and Biophysical Insights into SPINK1 Bound to Human Cationic Trypsin.
Int J Mol Sci, 23, 2022
7QE9
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Human cationic trypsin (TRY1) complexed with serine protease inhibitor Kazal type 1 N34S (SPINK1 N34S)
分子名称: SULFATE ION, Serine protease inhibitor Kazal-type 1, Trypsin-1
著者Nagel, F, Palm, G.J, Delcea, M, Lammers, M.
登録日2021-12-01
公開日2022-03-30
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and Biophysical Insights into SPINK1 Bound to Human Cationic Trypsin.
Int J Mol Sci, 23, 2022
1HJA
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BU of 1hja by Molmil
LYS 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH ALPHA-CHYMOTRYPSIN
分子名称: ALPHA-CHYMOTRYPSIN, OVOMUCOID INHIBITOR
著者Ding, J.-H, James, M.N.G.
登録日1997-07-09
公開日1998-01-14
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of Lys18 Variant of Turkey Ovomucoid Inhibitor Third Domain Complexed with Alpha-Chymotrypsin at 2.3 A
To be Published
2BUS
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SOLUTION CONFORMATION OF PROTEINASE INHIBITOR IIA FROM BULL SEMINAL PLASMA BY 1H NUCLEAR MAGNETIC RESONANCE AND DISTANCE GEOMETRY
分子名称: PROTEINASE INHIBITOR IIA
著者Guntert, P, Williamson, M.P, Havel, T.F, Wuthrich, K.
登録日1990-05-14
公開日1991-04-15
最終更新日2019-12-25
実験手法SOLUTION NMR
主引用文献Solution conformation of proteinase inhibitor IIA from bull seminal plasma by 1H nuclear magnetic resonance and distance geometry.
J.Mol.Biol., 182, 1985
1YU6
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Crystal Structure of the Subtilisin Carlsberg:OMTKY3 Complex
分子名称: CALCIUM ION, Ovomucoid, Subtilisin Carlsberg
著者Maynes, J.T, Cherney, M.M, Qasim, M.A, Laskowski Jr, M, James, M.N.G.
登録日2005-02-11
公開日2005-05-03
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structure of the subtilisin Carlsberg-OMTKY3 complex reveals two different ovomucoid conformations.
Acta Crystallogr.,Sect.D, 61, 2005
2F3C
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BU of 2f3c by Molmil
Crystal structure of infestin 1, a Kazal-type serineprotease inhibitor, in complex with trypsin
分子名称: CALCIUM ION, Cationic trypsin, SULFATE ION, ...
著者Campos, I.T.N, Tanaka, A.S, Barbosa, J.A.R.G.
登録日2005-11-20
公開日2006-12-05
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The Kazal-type inhibitors infestins 1 and 4 differ in specificity but are similar in three-dimensional structure.
Acta Crystallogr.,Sect.D, 68, 2012
3SGB
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STRUCTURE OF THE COMPLEX OF STREPTOMYCES GRISEUS PROTEASE B AND THE THIRD DOMAIN OF THE TURKEY OVOMUCOID INHIBITOR AT 1.8 ANGSTROMS RESOLUTION
分子名称: PROTEINASE B (SGPB), TURKEY OVOMUCOID INHIBITOR (OMTKY3)
著者Read, R.J, Fujinaga, M, Sielecki, A.R, James, M.N.G.
登録日1983-01-21
公開日1983-07-12
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of the complex of Streptomyces griseus protease B and the third domain of the turkey ovomucoid inhibitor at 1.8-A resolution.
Biochemistry, 22, 1983
3SGQ
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GLN 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 10.7
分子名称: Ovomucoid, PHOSPHATE ION, Streptogrisin B
著者Huang, K, Lu, W, Anderson, S, Laskowski Jr, M, James, M.N.G.
登録日1999-03-25
公開日2003-08-26
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Recruitment of a Buried K+ Ion to Stabilize the Negative Charge of Ionized P1 in the Hydrophobic Pocket: Crystal Structures of Glu18, Gln18, Asp18 and Asn18 Variants of Turkey Ovomucoid Inhibitor Third Domain Complexed with Streptomyces griseus Protease B at Various pH's
To be Published
3QTL
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Structural Basis for Dual-inhibition Mechanism of a Non-classical Kazal-type Serine Protease Inhibitor from Horseshoe Crab in Complex with Subtilisin
分子名称: Kazal-type serine protease inhibitor SPI-1, Subtilisin-like serin protease
著者Shenoy, R.T, Sivaraman, J.
登録日2011-02-23
公開日2011-06-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for dual-inhibition mechanism of a non-classical kazal-type serine protease inhibitor from horseshoe crab in complex with subtilisin.
Plos One, 6, 2011
3TJQ
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N-domain of HtrA1
分子名称: CHLORIDE ION, GLYCEROL, PLATINUM (II) ION, ...
著者Eigenbrot, C, Ultsch, M.
登録日2011-08-24
公開日2012-05-16
最終更新日2012-06-27
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Structural and Functional Analysis of HtrA1 and Its Subdomains.
Structure, 20, 2012
2SGP
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PRO 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 6.5
分子名称: OVOMUCOID INHIBITOR, PHOSPHATE ION, PROTEINASE B
著者Huang, K, Lu, W, Anderson, S, Laskowski Jr, M, James, M.N.G.
登録日1999-03-25
公開日2001-01-31
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Contribution of peptide bonds to inhibitor-protease binding: crystal structures of the turkey ovomucoid third domain backbone variants OMTKY3-Pro18I and OMTKY3-psi[COO]-Leu18I in complex with Streptomyces griseus proteinase B (SGPB) and the structure of the free inhibitor, OMTKY-3-psi[CH2NH2+]-Asp19I
J.Mol.Biol., 305, 2001
2SGQ
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GLN 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 6.5
分子名称: Ovomucoid, PHOSPHATE ION, Streptogrisin B
著者Huang, K, Lu, W, Anderson, S, Laskowski Jr, M, James, M.N.G.
登録日1999-03-25
公開日2003-08-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Recruitment of a Buried K+ Ion to Stabilize the Negative Charge of Ionized P1 in the Hydrophobic Pocket: Crystal Structures of Glu18, Gln18, Asp18 and Asn18 Variants of Turkey Ovomucoid Inhibitor Third Domain Complexed with Streptomyces griseus Protease B at Various pH's
To be Published
2SGE
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GLU 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 10.7
分子名称: Ovomucoid, PHOSPHATE ION, POTASSIUM ION, ...
著者Huang, K, Lu, W, Anderson, S, Laskowski Jr, M, James, M.N.G.
登録日1999-03-25
公開日2003-08-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Water molecules participate in proteinase-inhibitor interactions: crystal structures of Leu18, Ala18, and Gly18 variants of turkey ovomucoid inhibitor third domain complexed with Streptomyces griseus proteinase B.
Protein Sci., 4, 1995
2SGF
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PHE 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B
分子名称: Ovomucoid, PHOSPHATE ION, Streptogrisin B
著者Huang, K, Lu, W, Anderson, S, Laskowski Jr, M, James, M.N.G.
登録日1999-03-25
公開日2003-08-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Recruitment of a Buried K+ Ion to Stabilize the Negative Charge of Ionized P1 in the Hydrophobic Pocket: Crystal Structures of Glu18, Gln18, Asp18 and Asn18 Variants of Turkey Ovomucoid Inhibitor Third Domain Complexed with Streptomyces griseus Protease B at Various pHs
To be Published
2SGD
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ASP 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 10.7
分子名称: Ovomucoid, PHOSPHATE ION, POTASSIUM ION, ...
著者Huang, K, Lu, W, Anderson, S, Laskowski Jr, M, James, M.N.G.
登録日1999-03-25
公開日2003-08-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Recruitment of a Buried K+ Ion to Stabilize the Negative Charge of Ionized P1 in the Hydrophobic Pocket: Crystal Structures of Glu18, Gln18, Asp18 and Asn18 Variants of Turkey Ovomucoid Inhibitor Third Domain Complexed with Streptomyces griseus Protease B at Various pHs
To be Published

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